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Objective In this study, we present the results of a comparative research carried out on three cohorts of university students in the context of a pandemic. Several research indicate that the anxiety level of populations has increased significantly. Method In this article, we present the results of a comparative study of three cohorts study conducted on 1674 Quebec students. Participants were recruited at three separate time points, in the summer of 2020 (cohort 1; N = 398), in the fall of 2020 (cohort 2; N = 621) and in the winter of 2021 (cohort 3; N = 655). Anxiety was measured using Beck's anxiety inventory and several sociodemographic variables were tested. Results Results from cohort 1 indicate that being younger and having a mental health diagnosis may be vulnerability factors for anxiety. For cohort 2, the interaction of gender x diagnosis x program of study had a significant effect. Age and family income were predictive of significant anxiety in cohort 3. Limitations and perspectives of the study are explored. Conclusion The study recommends that the results be considered in developing preventive and intervention programs in the post-pandemic period.

Introduction: The coronavirus disease (COVID-19) pandemic has caused a major health crisis and the quarantine of most of the planet's population. During confinement, anxiety symptoms may appear. The pandemic dramatically changes the lives of individuals by becoming a concrete manifestation of the threat. Constant exposure to information about the virus can increase anxiety, especially since the information may be erroneous or contradictory. This article examines the factors that predict student anxiety in the context of a pandemic., Method: The quantitative study involves a sample of 445 students from the University of Quebec in Abitibi-Témiscamingue. Anxiety was measured using the Beck Anxiety Inventory, and several sociodemographic variables were tested., Results: The results demonstrated the effects of certain variables on anxiety, especially for women and non-binary people, were more marked than for men. Having dependent children has proven to be a protective factor., Conclusion: The study suggests that this variability is now considered when proposing intervention measures in a containment context. The limitations and perspectives of the study are presented and analyzed., (Copyright © 2021 L'Encéphale, Paris. Published by Elsevier Masson SAS. All rights reserved.)

Introduction: It is extremely rare that an inflammatory rheumatism reveals a hyperthyroidism. Only six observations have been described. We report a case of rheumatismal hyperthyroidism successfully treated with carbimazole and propranolol., Observation: A 52 year-old woman presented with inflammatory rheumatismal pain predominating at the waist for the past six months and resistant to synthetic anti-inflammatories. Thyroid hormone analysis permitted diagnosis of hyperthyroidism. Initiation of treatment with carbimazole led to the rapid regression of the rheumatismal manifestations., Comments: Hyperthyroidism is classically manifested by signs of hypercatabolism. Osteoarticular manifestations are dominated by humeroscapular periarthrosis. Rheumatismal hyperthyroidism is characterised by inflammatory rheumatismal pain evoking, as in our patient, a rhizomelic pseudo-polyarthritis. The outcome, whatever the anti-thyroid treatment, is always good. The physiopathological mechanisms are unknown. They may be due to an attack of the antibodies against the synovial and/or cartilage structures, or to the effect of propranolol., Conclusion: It is important to underline the interest of thyroid hormone assay in cases of dubious etiological inflammatory rheumatism and/or resistant to classical treatments.

Background: Pulmonary hypertension is an uncommon feature of Whipple's disease and the underlying pathophysiological mechanism remains a subject of debate., Case Report: A 57-year-old woman was hospitalized for exploration of migrating joint pain that had developed for 5 years. Histologically proven Whipple's disease was diagnosed on duodenal biopsies. The lung angiogram performed to explore signs of right heart failure demonstrated pulmonary hypertension and ruled out pulmonary embolism. Abundant pericardial effusion developed progressively. Antibiotic therapy using sulfamethoxazole-trimethoprime led to a systemic Jarisch Herxheilmer reaction. The pulmonary hypertension resolved rapidly, the pericardial effusion more slowly., Discussion: The pulmonary hypertension in this patient appeared to be directly related to Whipple's disease, probably via vascular infiltration by Tropheryma whippeli.

We report the case of a 52-year-old woman who presented hypoparathyroidism and sarcoidosis. The hypoparathyroidism developed 8 years after the diagnosis of sarcoidosis. No element in favor of an autoimmune disease of the parathyroid could be evidenced. Pathology and immunology blood tests were equally noncontributive. Another pathophysiological mechanism, possibly sarcoidic granulomatous infiltration of the parathyroid glands, was suspected. The patient also presented apparently coincidental vitiligo.

Background: Vitamin B1 deficiency (beriberi) is very uncommon in France. It leads to high output cardiac failure totally different from the situation observed in alcoholic patients. We report a typical case of cardiac beriberi., Case Report: The patient was referred for dyspnea with high output cardiac failure. Echocardiography evidenced severe pulmonary hypertension and high cardiac output. The more common causes of heart failure were ruled out. The dietary habits of the patient (suggested beriberi which was confirmed by the low serum thiamin and therapeutic test with vitamin B1., Discussion: High output cardiac failure should suggest possible Shoshin beriberi, particularly in subjects with imported dietary habits living in a precarious socioeconomic situation.