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210 results on '"Rosti, Giovanni"'

3. Recommendations for surveillance and follow-up of men with testicular germ cell tumors: a multidisciplinary consensus conference by the Italian Germ cell cancer Group and the Associazione Italiana di Oncologia Medica

Author

Banna, Giuseppe Luigi, Nicolai, Nicola, Palmieri, Giovannella, Ottaviano, Margaret, Balzarini, Luca, Barone, Domenico, Basso, Umberto, Bavila, Alessandro, Bertoni, Filippo, Calliada, Fabrizio, Cai, Tommaso, Carrafiello, Gianpaolo, Condello, Caterina, Da Pozzo, Luigi, Di Nardo, Domenico, Fornarini, Giuseppe, Prayer Galetti, Tommaso, Garolla, Andrea, Giannatempo, Patrizia, Guerra, Luca, La Spina, Sonia, Malatino, Lorenzo, Marchiano', Alfonso, Monti, Mirko, Morbiato, Francesco Filippo, Morelli, Franco, Nole', Franco, Palazzi, Silvia, Procopio, Giuseppe, Rosti, Giovanni, Sacco, Cosimo, Salvetti, Andrea, Salvioni, Roberto, Sava, Teodoro, Secondino, Simona, Serpentini, Samantha, Spreafico, Carlo, Tavolini, Ivan Matteo, Valcamonico, Francesca, Verri, Elena, Zucali, Paolo, and De Giorgi, Ugo

Published
2019
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4. Hyperthyroidism in non-seminomatous testicular germ cell tumors: two case reports and literature review.

Author

Favero, Diletta, Oing, Christoph, Seidel, Christoph, Rescigno, Pasquale, Catalano, Fabio, Cremante, Malvina, Rebuzzi, Sara Elena, Gatto, Federico, Rosti, Giovanni, Ferone, Diego, Fornarini, Giuseppe, and Cocchiara, Francesco

Subjects
LITERATURE reviews, GERM cell tumors, HYPERTHYROIDISM, CHORIONIC gonadotropins, SYMPTOMS, HORMONE receptors
Abstract

Background: Human chorionic gonadotropin (hCG)-induced hyperthyroidism is a rare paraneoplastic syndrome observed in non-seminomatous testicular germ cell tumors, due to a cross-reaction between the b-subunit of hCG with the thyroid-stimulating hormone receptor. The precise prevalence of this paraneoplastic phenomenon is unclear as, in the majority of cases, hyperthyroidism remains subclinical. Case presentation: Here, we present two cases of advanced metastatic nonseminomatous testicular germ cell tumors where patients exhibited signs and symptoms of thyrotoxicosis at primary diagnosis due to excessive serum b-hCG elevation, with complete remission of symptomatology after the start of oncological treatments and no signs of relapse at the time of publication of this report. Additionally, we provide a comprehensive review of the existing literature concerning this uncommon occurrence. Conclusion: Despite being a rare event, the presence of hyperthyroidism or thyrotoxicosis without clear etiology in a young man should lead to consider less frequent causes such as testicular tumors. Even if patients typically have mild symptoms that resolve after chemotherapy, in rare cases, it can be a life-threatening condition that requires prompt recognition and specific intervention. [ABSTRACT FROM AUTHOR]

Published
2024
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5. Salvage High-Dose Chemotherapy for Relapsed Pure Seminoma in the Last 10 Years: Results From the European Society for Blood and Marrow Transplantation Series 2002-2012

Author

Necchi, Andrea, Lo Vullo, Salvatore, Bregni, Marco, Rosti, Giovanni, Mariani, Luigi, Raggi, Daniele, Giannatempo, Patrizia, Secondino, Simona, Schumacher, Kathrin, Massard, Christophe, Kanfer, Edward, Oechsle, Karin, Laszlo, Daniele, Michieli, Mariagrazia, Ifrah, Norbert, Mercier, Melanie, Crysandt, Martina, Wuchter, Patrick, Nagler, Arnon, Wahlin, Anders, Martino, Massimo, Badoglio, Manuela, Pedrazzoli, Paolo, and Lanza, Francesco

Published
2017
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6. Comparison of the Tolerability Profile of Controlled-Release Oral Morphine and Oxycodone for Cancer Pain Treatment. An Open-Label Randomized Controlled Trial

Author

Zecca, Ernesto, Brunelli, Cinzia, Bracchi, Paola, Biancofiore, Giuseppe, De Sangro, Carlo, Bortolussi, Roberto, Montanari, Luigi, Maltoni, Marco, Moro, Cecilia, Colonna, Ugo, Finco, Gabriele, Roy, Maria Teresa, Ferrari, Vittorio, Alabiso, Oscar, Rosti, Giovanni, Kaasa, Stein, and Caraceni, Augusto

Published
2016
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7. Secondary malignancies after high-dose chemotherapy in germ cell tumor patients: a 34-year retrospective study of the European Society for Blood and Marrow Transplantation (EBMT)

Author

Necchi, Andrea, Lo Vullo, Salvatore, Secondino, Simona, Rosti, Giovanni, Badoglio, Manuela, Giannatempo, Patrizia, Raggi, Daniele, Lanza, Francesco, Chabannon, Christian, Bonini, Chiara, Mariani, Luigi, Pedrazzoli, Paolo, and on behalf of the European Society for Blood and Marrow Transplantation, Cellular Therapy & Immunobiology Working Party – Solid Tumor sub-committee

Published
2018
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8. High-Dose Chemotherapy and Autologous Hematopoietic Stem Cell Transplantation as Adjuvant Treatment in High-Risk Breast Cancer: Data from the European Group for Blood and Marrow Transplantation Registry

Author

Martino, Massimo, Lanza, Francesco, Pavesi, Lorenzo, Öztürk, Mustafa, Blaise, Didier, Leno Núñez, Rubén, Schouten, Harry C., Bosi, Alberto, De Giorgi, Ugo, Generali, Daniele, Rosti, Giovanni, Necchi, Andrea, Ravelli, Andrea, Bengala, Carmelo, Badoglio, Manuela, Pedrazzoli, Paolo, and Bregni, Marco

Published
2016
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12. Standard vs Adapted Sunitinib Regimen in Elderly Patients With Metastatic Renal Cell Cancer: Results From a Large Retrospective Analysis

Author

De Giorgi, Ugo, Scarpi, Emanuela, Sacco, Cosimo, Aieta, Michele, Lo Re, Giovanni, Sava, Teodoro, Masini, Cristina, De Vincenzo, Fabio, Baldazzi, Valentina, Camerini, Andrea, Fornarini, Giuseppe, Burattini, Luciano, Rosti, Giovanni, Ferrari, Vittorio, Moscetti, Luca, Chiuri, Vincenzo Emanuele, Luzi Fedeli, Stefano, Amadori, Dino, and Basso, Umberto

Published
2014
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13. Adjuvant High-Dose Chemotherapy with Autologous Hematopoietic Stem Cell Support for High-Risk Primary Breast Cancer: Results from the Italian National Registry

Author

Pedrazzoli, Paolo, Martinelli, Giovanni, Gianni, Alessandro Massimo, Da Prada, Gian Antonio, Ballestrero, Alberto, Rosti, Giovanni, Frassineti, Giovanni Luca, Aieta, Michele, Secondino, Simona, Cinieri, Saverio, Fedele, Roberta, Bengala, Carmelo, Bregni, Marco, Grasso, Donatella, De Giorgi, Ugo, Lanza, Francesco, Castagna, Luca, Bruno, Barbara, and Martino, Massimo

Published
2014
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14. Lymphopenia and clinical outcome of elderly patients treated with sunitinib for metastatic renal cell cancer

Author

De Giorgi, Ugo, Rihawi, Karim, Aieta, Michele, Lo Re, Giovanni, Sava, Teodoro, Masini, Cristina, Baldazzi, Valentina, De Vincenzo, Fabio, Camerini, Andrea, Fornarini, Giuseppe, Burattini, Luciano, Rosti, Giovanni, Moscetti, Luca, Chiuri, Vincenzo E., Luzi Fedeli, Stefano, Ferrari, Vittorio, Scarpi, Emanuela, Amadori, Dino, and Basso, Umberto

Published
2014
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17. Spermatocytic Tumor: A Review.

Author

Secondino, Simona, Viglio, Alessandra, Neri, Giuseppe, Galli, Giulia, Faverio, Carlotta, Mascaro, Federica, Naspro, Richard, Rosti, Giovanni, and Pedrazzoli, Paolo

Subjects
GERM cell tumors, TESTICULAR cancer, TUMORS, DATA libraries, SEMINOMA
Abstract

Spermatocytic tumor (ST) is a very rare disease, accounting for approximately 1% of testicular cancers. Previously classified as spermatocytic seminoma, it is currently classified within the non-germ neoplasia in-situ-derived tumors and has different clinical-pathologic features when compared with other forms of germ cell tumors (GCTs). A web-based search of MEDLINE/PubMed library data was performed in order to identify pertinent articles. In the vast majority of cases, STs are diagnosed at stage I and carry a very good prognosis. The treatment of choice is orchiectomy alone. Nevertheless, there are two rare variants of STs having very aggressive behavior, namely anaplastic ST and ST with sarcomatous transformation, that are resistant to systemic treatments and their prognosis is very poor. We have summarized all the epidemiological, pathological and clinical features available in the literature regarding STs that have to be considered as a specific entity compared to other germ GCTs, including seminoma. With the aim of improving the knowledge of this rare disease, an international registry is required. [ABSTRACT FROM AUTHOR]

Published
2023
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21. Testicular tumors in the “elderly” population.

Author

Secondino, Simona, Rosti, Giovanni, Tralongo, Antonino C., Nolè, Franco, Alaimo, Domiziana, Carminati, Ornella, John Naspro, Richard Lawrence, and Pedrazzoli, Paolo

Subjects
TESTICULAR cancer, GERM cell tumors, OLDER people, PINEAL gland, TUMORS, SEMINOMA
Abstract

Germ cell tumors arise in childhood but peak at around 30 years of age. They are the most common cancers in males under the age of 35. Over 95% arise in the testes while a minority originate in extragonadal sites such as the anterior mediastinum, or mainly in childhood the pineal gland or the sacrococcygeal area. These tumors show an extraordinary sensitivity to chemotherapy (and for seminoma, also to radiation) and cure rates are relatively high even in second or subsequent relapses. Very few data are present in the literature regarding patients diagnosed after 50 years and no specific trials have been conducted in this setting. Nearly all patients reported in the literature had testicular cancers, with occasional reports of extragonadal tumors. Despite the fact that > 50 years may be considered an “elderly” population, these patients are treated with the same cisplatin containing combinations as their younger counterparts with consequent higher toxicity. In this review we will present epidemiological and clinical data from this rare population of patients with testicular cancer. [ABSTRACT FROM AUTHOR]

Published
2022
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23. European Consensus Conference on Diagnosis and Treatment of Germ Cell Cancer: A Report of the Second Meeting of the European Germ Cell Cancer Consensus group (EGCCCG): Part I

Author

Krege, Susanne, Beyer, Jörg, Souchon, Rainer, Albers, Peter, Albrecht, Walter, Algaba, Ferran, Bamberg, Michael, Bodrogi, István, Bokemeyer, Carsten, Cavallin-Ståhl, Eva, Classen, Johannes, Clemm, Christoph, Cohn-Cedermark, Gabriella, Culine, Stéphane, Daugaard, Gedske, De Mulder, Pieter H.M., De Santis, Maria, de Wit, Maike, de Wit, Ronald, Derigs, Hans Günter, Dieckmann, Klaus-Peter, Dieing, Annette, Droz, Jean-Pierre, Fenner, Martin, Fizazi, Karim, Flechon, Aude, Fosså, Sophie D., Garcia del Muro, Xavier, Gauler, Thomas, Geczi, Lajos, Gerl, Arthur, Germa-Lluch, Jose Ramon, Gillessen, Silke, Hartmann, Jörg T., Hartmann, Michael, Heidenreich, Axel, Hoeltl, Wolfgang, Horwich, Alan, Huddart, Robert, Jewett, Michael, Joffe, Johnathan, Jones, William G., Kisbenedek, László, Klepp, Olbjørn, Kliesch, Sabine, Koehrmann, Kai Uwe, Kollmannsberger, Christian, Kuczyk, Markus, Laguna, Pilar, Leiva Galvis, Oscar, Loy, Volker, Mason, Malcolm D., Mead, Graham M., Mueller, Rolf, Nichols, Craig, Nicolai, Nicola, Oliver, Tim, Ondrus, Dalibor, Oosterhof, Gosse O.N., Paz Ares, Luis, Pizzocaro, Giorgio, Pont, Jörg, Pottek, Tobias, Powles, Tom, Rick, Oliver, Rosti, Giovanni, Salvioni, Roberto, Scheiderbauer, Jutta, Schmelz, Hans-Ulrich, Schmidberger, Heinz, Schmoll, Hans-Joachim, Schrader, Mark, Sedlmayer, Felix, Skakkebaek, Niels E., Sohaib, Aslam, Tjulandin, Sergei, Warde, Padraig, Weinknecht, Stefan, Weissbach, Lothar, Wittekind, Christian, Winter, Eva, Wood, Lori, and von der Maase, Hans

Published
2008
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25. ☆Corrigendum to “Recommendations for surveillance and follow-up of men with testicular germ cell tumors: A multidisciplinary consensus conference by the Italian Germ cell cancer Group and the Associazione Italiana di Oncologia Medica” [Crit. Rev. Oncol. Hematol. 137 (2019) (May) 154–164]

Author

Banna, Giuseppe Luigi, Nicolai, Nicola, Palmieri, Giovannella, Ottaviano, Margaret, Balzarini, Luca, Barone, Domenico, Basso, Umberto, Bavila, Alessandro, Bertoni, Filippo, Calliada, Fabrizio, Cai, Tommaso, Carrafiello, Gianpaolo, Condello, Caterina, Da Pozzo, Luigi, Di Nardo, Domenico, Fornarini, Giuseppe, Galetti, Tommaso Prayer, Garolla, Andrea, Giannatempo, Patrizia, Guerra, Luca, La Spina, Sonia, Malatino, Lorenzo, Marchiano', Alfonso, Monti, Mirko, Morbiato, Francesco Filippo, Morelli, Franco, Nole', Franco, Palazzi, Silvia, Procopio, Giuseppe, Rosti, Giovanni, Sacco, Cosimo, Salvetti, Andrea, Salvioni, Roberto, Sava, Teodoro, Secondino, Simona, Serpentini, Samantha, Spreafico, Carlo, Tavolini, Ivan Matteo, Valcamonico, Francesca, Verri, Elena, Zucali, Paolo, and De Giorgi, Ugo

Published
2020
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26. Inflammatory Biomarkers for Outcome Prediction in Patients With Metastatic Testicular Cancer.

Author

Bleve, Sara, Cursano, Maria Concetta, Casadei, Chiara, Schepisi, Giuseppe, Menna, Cecilia, Urbini, Milena, Gianni, Caterina, De Padova, Silvia, Filograna, Alessia, Gallà, Valentina, Rosti, Giovanni, Barone, Domenico, Chovanec, Michal, Mego, Michal, and De Giorgi, Ugo

Subjects
TESTICULAR cancer, METASTASIS, GERM cell tumors, DISEASE relapse, PROGNOSIS, THERAPEUTICS
Abstract

Germ cell tumors are the most common malignant tumors in male young adults. Platinum-based chemotherapy has dramatically improved the outcome of metastatic germ cell tumor patients and overall cure rates now exceed 80%. The choice of medical treatment can be guided by the prognosis estimation which is an important step during the decision-making process. IGCCCG classification plays a pivotal role in the management of advanced disease. However, histological and clinical parameters are the available factors that condition the prognosis, but they do not reflect the tumor's molecular and pathological features and do not predict who will respond to chemotherapy. After first-line chemotherapy 20%-30% of patients relapse and for these patients, the issue of prognostic factors is far more complex. Validated biomarkers and a molecular selection of patients that reflect the pathogenesis are highly needed. The association between cancer-related systemic inflammation, tumorigenesis, and cancer progression has been demonstrated. In the last years, several studies have shown the prognostic utility of immune-inflammation indexes in different tumor types. This review analyzed the prognostic impact of inflammatory markers retrieved from routine blood draws in GCT patients. [ABSTRACT FROM AUTHOR]

Published
2022
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30. Clinical activity and cardiac tolerability of non-pegylated liposomal doxorubicin in breast cancer: a synthetic review

Author

Airoldi, Mario, Amadori, Dino, Barni, Sandro, Cinieri, Saverio, De Placido, Sabino, Di Leo, Angelo, Gennari, Alessandra, Iacobelli, Stefano, Ionta, Maria Teresa, Lorusso, Vito, Lotrionte, Marzia, Marchetti, Paolo, Mattioli, Rodolfo, Minotti, Giorgio, Pronzato, Paolo, Rosti, Giovanni, Tondini, Carlo Alberto, and Veronesi, Andrea

Published
2011
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37. Phase II study of intensive chemotherapy with carboplatin, ifosfamide and etoposide plus recombinant human granulocyte colony-stimulating factor and sequential radiotherapy in locally advanced, unresectable non-small-cell lung cancer

Author

Scagliotti, Giorgio Vittorio, Ricardi, Umberto, Crinó, Lucio, Maranzano, Ernesto, Marinis, Filippo De, Morandi, Maria Grazia, Meacci, Luisa, Marangolo, Maurizio, Emiliani, Ermanno, Rosti, Giovanni, Figoli, Franco, Bolzicco, Gianfranco, Masiero, Paolo, Gentile, Alfonso, and Tonato, Maurizio

Published
1996
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38. Germ-Cell Tumors

Author

De Giorgi, Ugo, Pedrazzoli, Paolo, Rosti, Giovanni, and Osseo, di Midollo

Published
2007

40. Prognostic factors for survival in patients with advanced renal cell carcinoma undergoing nonmyeloablative allogeneic stem cell transplantation

Author

Peccatori, Jacopo, Barkholt, Lisbeth, Demirer, Tanner, Sormani, Maria Pia, Bruzzi, Paolo, Ciceri, Fabio, Zambelli, Alberto, Da Prada, Gian Antonio, Pedrazzoli, Paolo, Siena, Salvatore, Massenkeil, Gero, Martino, Rodrigo, Lenhoff, Stig, Corradini, Paolo, Rosti, Giovanni, Ringden, Olle, Bregni, Marco, and Niederwieser, Dietger

Published
2005
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50. Glaucoma and paclitaxel

Author

De Giorgi, Ugo, Acciarri, Riccardo, Fiorentini, Giammaria, Rosti, Giovanni, and Marangolo, Maurizio

Published
2000

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