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Wear on the surface of the femoral head increases the risk of hip and femur fractures. Biomechanical experiments conducted on the femur are based on its bending and torsional rigidities. Studies regarding the deflection of the femur bone when the femoral head is coated with microfilms composed of durable and compatible biomaterials are poor. This study aimed to investigate the effects of different biomaterial microfilm coatings over the femoral head on the deflection of the human femur. We utilized 2023 R1 finite element analysis (FEA) software to model the directional deformation on the femoral head and examine the femur's deflection with varying microfilm thicknesses. The deflection of the femur bone was reported when the femoral head was uncoated and coated with titanium, stainless steel, and pure gold microfilms of different thicknesses (namely, 50, 75, and 100 μm). Our results show that the femur's minimum and maximum deflection occurred for stainless steel and gold, respectively. The deformation of the femur was lower when the femoral head was coated with a 50-micrometer microfilm of stainless steel, compared to the deformation obtained with gold and titanium. When the thickness of the microfilm for each of the materials was increased, the deformation continued to decrease. The minimum deformation of the femur occurred for a thickness of 100 μm with stainless steel, followed by titanium and gold. The difference in the directional deformation of the femur between the materials was more significant when the coating was 100 μm, compared to the thicknesses of 50 and 75 μm. The findings of this study are expected to significantly contribute to the development of advanced medical techniques to enhance the quality of life for patients with femur bone-related issues. This information can be used to develop more resilient coatings that can withstand wear and tear. [ABSTRACT FROM AUTHOR]

Lymphoid interstitial pneumonia (LIP) is a rare form of interstitial pulmonary disease, which has been described in association with a wide range of autoimmune disorders. Although the association of this entity with Sjogren's syndrome is well known, only a few cases are reported in relation to systemic lupus erythematosus (SLE). The aim of this paper is to review the cases reported in literature to date, as well as to describe the characteristics of these patients including the new case presented herein. We will be focusing on the case of a 36-year-old female patient diagnosed with SLE on hydroxychloroquine treatment who develops pleuritic chest pain and progressive dyspnea after 3 years of follow-up. The chest CT scan showed pleural thickening and both multiple and bilateral micronodules. A lung biopsy was also performed, revealing an infiltration of lymphocytes, plasma cells, and histiocytes in the alveolar septa suggestive of LIP. After conducting a review of the literature, we identified seven other cases describing SLE in association with LIP. The majority of them were young women, and LIP tends to appear early in the course of the disease, even as a form of initial presentation in some cases. Symptoms included cough, dyspnea, and pleuritic pain, with the exception of one case which was asymptomatic. It is noteworthy that half of the patients were positive for anti-SSA/anti-SSB autoantibodies, and some of them also met criteria for Sjogren's syndrome. Treatment with steroids and other immunosuppressive agents improved symptoms in all of them. [ABSTRACT FROM AUTHOR]

This work aims to contribute to studies on the geometric optimization of thermoelectric generators (T E G s) through a combination of the reduced variables technique and supervised machine learning. The architecture of the thermoelectric generators studied, one conventional and the other segmented, was determined by calculating the cross-sectional area and length of the legs, and applying reduced variables approximation. With the help of a supervised machine learning algorithm, the values of the thermoelectric properties were predicted, as were those of the maximum electrical power for the other temperature values. This characteristic was an advantage that allowed us to obtain approximate results for the electrical power, adjusting the design of the T E G s when experimental values were not known. The proposed method also made it possible to determine the optimal values of various parameters of the legs, which were the ratio of the cross-sectional areas (A p / A n) , the length of the legs (l) , and the space between the legs (H) . Aspects such as temperature-dependent thermoelectric properties (Seebeck coefficient, electrical resistivity, and thermal conductivity) and the metallic bridge that connects the legs were considered in the calculations for the design of the T E G s , obtaining more realistic models. In the training phase, the algorithm received the parameter (H) and an operating temperature value as input data, to predict the corresponding value of the maximum power produced. This calculation was performed for conventional and segmented systems. Recent advances have opened up the possibility of applying an algorithm for designing conventional and segmented thermocouples based on the reduced variables approach and incorporating a supervised machine learning computational technique. [ABSTRACT FROM AUTHOR]

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Background: Spasticity is a frequent symptom of multiple sclerosis (MS), which may negatively influence daily living activities (ADL). Objectives: To (1) explore the feasibility to conduct a structured interview by specialist nurses about limitations in ADL; (2) determine the percentage of people with MS (PwMS) with limitations in ADL related to spasticity; (3) to assess the knowledge about spasticity and describe its clinical features. Design: Observational, cross‐sectional, multicentre study in 16 MS units of Catalonia (Spain). Participants were recruited from the outpatient facility and day‐care hospital between July 2018 and June 2019 and met the following criteria: (1) age 18 or older, (2) diagnosis of MS according to McDonald criteria 2010 and (3) no clinical relapse in previous 30 days. Methods: Specialist nurses conducted a structured interview divided in two parts: the assessment of (1) limitations in the ADL and (2) the presence of spasticity and associated symptoms. The usefulness of this intervention was requested. This study met the STROBE reporting guidelines checklist for observational studies. Results: Three hundred sixty eight pwMS (244 women) with a mean age of 46 years and a median Expanded Disability Status Scale score of 2.5 (range, 0–8.5) were included. 262 (71%) pwMS had limitations in the ADL, and spasticity was reported as the most limiting symptom in 59 (23%). As a result of the interview, spasticity was observed in 199 (76%) participants; 47 (24%) of them were unaware that they had spasticity and 102 (51%) would not have reported it spontaneously. The level of the interview satisfaction was high (90%). Conclusions: Spasticity is a complex and limiting symptom in MS. The structured interview conducted by specialist nurses is feasible and has good acceptance. Patient contribution Specialist nurses can be proactive in MS clinical assessment, which may help to detect symptoms with negative impact on quality of life. [ABSTRACT FROM AUTHOR]

Copyright of Artnodes is the property of Universitat Oberta de Catalunya and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

A thermoelectric generator (TEG) is studied by considering different leg structures of hollow/filled legs, using new cooling nanofluids, and analyzing the segmentation effect. TEG performance is characterized by power output, conversion efficiency, and exergy efficiency. This study shows the impact of different cooling nanofluids (TiO2, graphene, and Al2O3) on the performance of the thermoelectric generator. Furthermore, in the comparative analysis of nanofluid cooling enhancement for TEG, different hollow/filled thermoelectric legs recently proposed in the literature are considered. Likewise, three segmentation types are used, 2n-2p, 1n-2p, and 2n-1p, thus will be compared with the results of the unsegmented legs. This study calculates the performance of thermoelectric leg structures through a validated numerical simulation on the ANSYS Workbench (modeling, design, and simulation). In addition, the optimal working conditions are evaluated. This study found that quenching of nanofluids can improve TEG performance by up to 17% compared to distilled water. However, the performance improvement of the TEG for each nanofluid is small between them. Furthermore, segmentation of n-type thermocouples improves efficiency and exergy, whereas segmentation of p-type thermocouples improves output power. The segmentation enhances performance by up to twice that of non-segmented leg structures; hollow structures are better performers. In the results, it is reported that the 2n-1p segmentation is the one with the best performance, reaching a maximum energy efficiency of 38%. The triangular leg structure improves performance by up to 75% compared to the rectangular and square leg structures. Likewise, using TiO2 is the best cooling option with nanofluids since it improves performance by 17% compared to distilled water. Furthermore, the results of cooling nanofluids for TEG performance are useful for the design of thermoelectric leg structures and stimulate further research. [ABSTRACT FROM AUTHOR]

Roof runoff is collected rainwater from a roof using a rainwater harvesting system (RWHS). The construction of an efficient RWHS requires a thorough analysis of the rainwater quality and the appropriate treatment process for its intended use. In line with this, a bibliometric and comprehensive review of studies related to roof rainwater harvesting was conducted. A corpus of 1123 articles was downloaded from the Scopus database and parsed through the CorText Manager to determine the relationships between keywords, journals, and topics related to rainwater harvesting. A comprehensive analysis was also conducted to determine the different designs of RWHS, the quality of harvested rainwater from roof catchments, the efficiency of the system for specific purposes, and its sustainability in terms of economic, environmental, and social aspects. Results show that the effectiveness of a RWHS heavily depends on its installation site, the physicochemical characteristics of the harvested rainwater, and the acceptability of the end users. An effective water treatment process is essential for achieving better water quality for harvested rainwater. Moreover, assessing the financial viability and return on investment of an RWHS is necessary. [ABSTRACT FROM AUTHOR]

Copyright of Ecosistemas y Recursos Agropecuarios is the property of Universidad Juarez Autonoma de Tabasco and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Terra Latinoamericana is the property of Sociedad Mexicana de la Ciencia del Suelo A.C. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Terra Latinoamericana is the property of Sociedad Mexicana de la Ciencia del Suelo A.C. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Gaceta Médica de Caracas is the property of Academia Nacional de Medicina and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)