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Start Over Descriptor "Riociguat, exercise response" Publication Type Academic Journals
1 results on '"Riociguat, exercise response"'

1. Beneficial effects of riociguat on hemodynamic responses to exercise in CTEPH patients after balloon pulmonary angioplasty – A randomized controlled study

Author

Tatsuo Aoki, Koichiro Sugimura, Yosuke Terui, Shunsuke Tatebe, Shigefumi Fukui, Masanobu Miura, Saori Yamamoto, Nobuhiro Yaoita, Hideaki Suzuki, Haruka Sato, Katsuya Kozu, Ryo Konno, Satoshi Miyata, Kotaro Nochioka, Kimio Satoh, and Hiroaki Shimokawa

Subjects
Chronic thromboembolic pulmonary hypertension, Balloon pulmonary angioplasty, Riociguat, exercise response, Diseases of the circulatory (Cardiovascular) system, RC666-701
Abstract

Background: Although balloon pulmonary angioplasty (BPA) improves symptoms and pulmonary hemodynamics in patients with chronic thromboembolic pulmonary hypertension (CTEPH), the effects of riociguat on hemodynamics and exercise capacity in patients after BPA remain to be elucidated. Methods and Results: This study was a single-center, prospective, randomized, open-label trial. From November 2015 to November 2018, we prospectively examined 21 patients with CTEPH (65 ± 9 years old, M/F 2/19) who showed hemodynamic improvement with mean pulmonary arterial pressure (mPAP)

Published
2020
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