1. Extraskeletal osteosarcoma of the breast in an adolescent girl.
- Author
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Zils K, Ebner F, Ott M, Müller J, Baumhoer D, Greulich M, Rehnitz D, Rempen A, Schaetzle S, Wilhelm M, and Bielack S
- Subjects
- Adolescent, Bone Neoplasms drug therapy, Breast Neoplasms drug therapy, Chemotherapy, Adjuvant, Chondroblastoma drug therapy, Cisplatin administration & dosage, Doxorubicin administration & dosage, Female, Humans, Ifosfamide administration & dosage, Methotrexate administration & dosage, Neoplasm Grading, Osteosarcoma drug therapy, Treatment Outcome, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Bone Neoplasms secondary, Breast Neoplasms pathology, Chondroblastoma secondary, Osteosarcoma secondary
- Abstract
Extraskeletal osteosarcoma (ESOS) is a rare malignancy, usually arising in older adults. We were unable to find reports of children or adolescents affected by an ESOS of the breast. Here, we present the case of a high-grade osteosarcoma arising in the breast of a 16-year-old girl. The tumor was treated with breast-conserving resections and adjuvant multiagent chemotherapy, based on a regimen of doxorubicin, high-dose methotrexate, cisplatin, and ifosfamide. At last follow-up, the patient was in first complete remission, 29 months after initial diagnosis.
- Published
- 2012
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