247 results on '"Protheroe, Andrew"'
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2. Genomic landscape of adult testicular germ cell tumours in the 100,000 Genomes Project
- Author
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Ní Leathlobhair, Máire, Frangou, Anna, Kinnersley, Ben, Cornish, Alex J., Chubb, Daniel, Lakatos, Eszter, Arumugam, Prabhu, Gruber, Andreas J., Law, Philip, Tapinos, Avraam, Jakobsdottir, G. Maria, Peneva, Iliana, Sahli, Atef, Smyth, Evie M., Ball, Richard Y., Sylva, Rushan, Benes, Ksenija, Stark, Dan, Young, Robin J., Lee, Alexander T. J., Wolverson, Vincent, Houlston, Richard S., Sosinsky, Alona, Protheroe, Andrew, Murray, Matthew J., Wedge, David C., and Verrill, Clare
- Published
- 2024
- Full Text
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3. Multi-ancestry genome-wide association study of kidney cancer identifies 63 susceptibility regions
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Purdue, Mark P., Dutta, Diptavo, Machiela, Mitchell J., Gorman, Bryan R., Winter, Timothy, Okuhara, Dayne, Cleland, Sara, Ferreiro-Iglesias, Aida, Scheet, Paul, Liu, Aoxing, Wu, Chao, Antwi, Samuel O., Larkin, James, Zequi, Stênio C., Sun, Maxine, Hikino, Keiko, Hajiran, Ali, Lawson, Keith A., Cárcano, Flavio, Blanchet, Odile, Shuch, Brian, Nepple, Kenneth G., Margue, Gaëlle, Sundi, Debasish, Diver, W. Ryan, Folgueira, Maria A. A. K., van Bokhoven, Adrie, Neffa, Florencia, Brown, Kevin M., Hofmann, Jonathan N., Rhee, Jongeun, Yeager, Meredith, Cole, Nathan R., Hicks, Belynda D., Manning, Michelle R., Hutchinson, Amy A., Rothman, Nathaniel, Huang, Wen-Yi, Linehan, W. Marston, Lori, Adriana, Ferragu, Matthieu, Zidane-Marinnes, Merzouka, Serrano, Sérgio V., Magnabosco, Wesley J., Vilas, Ana, Decia, Ricardo, Carusso, Florencia, Graham, Laura S., Anderson, Kyra, Bilen, Mehmet A., Arciero, Cletus, Pellegrin, Isabelle, Ricard, Solène, Scelo, Ghislaine, Banks, Rosamonde E., Vasudev, Naveen S., Soomro, Naeem, Stewart, Grant D., Adeyoju, Adebanji, Bromage, Stephen, Hrouda, David, Gibbons, Norma, Patel, Poulam, Sullivan, Mark, Protheroe, Andrew, Nugent, Francesca I., Fournier, Michelle J., Zhang, Xiaoyu, Martin, Lisa J., Komisarenko, Maria, Eisen, Timothy, Cunningham, Sonia A., Connolly, Denise C., Uzzo, Robert G., Zaridze, David, Mukeria, Anush, Holcatova, Ivana, Hornakova, Anna, Foretova, Lenka, Janout, Vladimir, Mates, Dana, Jinga, Viorel, Rascu, Stefan, Mijuskovic, Mirjana, Savic, Slavisa, Milosavljevic, Sasa, Gaborieau, Valérie, Abedi-Ardekani, Behnoush, McKay, James, Johansson, Mattias, Phouthavongsy, Larry, Hayman, Lindsay, Li, Jason, Lungu, Ilinca, Bezerra, Stephania M., Souza, Aline G., Sares, Claudia T. G., Reis, Rodolfo B., Gallucci, Fabio P., Cordeiro, Mauricio D., Pomerantz, Mark, Lee, Gwo-Shu M., Freedman, Matthew L., Jeong, Anhyo, Greenberg, Samantha E., Sanchez, Alejandro, Thompson, R. Houston, Sharma, Vidit, Thiel, David D., Ball, Colleen T., Abreu, Diego, Lam, Elaine T., Nahas, William C., Master, Viraj A., Patel, Alpa V., Bernhard, Jean-Christophe, Freedman, Neal D., Bigot, Pierre, Reis, Rui M., Colli, Leandro M., Finelli, Antonio, Manley, Brandon J., Terao, Chikashi, Choueiri, Toni K., Carraro, Dirce M., Houlston, Richard, Eckel-Passow, Jeanette E., Abbosh, Philip H., Ganna, Andrea, Brennan, Paul, Gu, Jian, and Chanock, Stephen J.
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- 2024
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4. Transcriptome- and proteome-wide association studies identify genes associated with renal cell carcinoma
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Purdue, Mark P., Dutta, Diptavo, Machiela, Mitchell J., Gorman, Bryan R., Winter, Timothy, Okuhara, Dayne, Cleland, Sara, Ferreiro-Iglesias, Aida, Scheet, Paul, Liu, Aoxing, Wu, Chao, Antwi, Samuel O., Larkin, James, Zequi, Stênio C., Sun, Maxine, Hikino, Keiko, Hajiran, Ali, Lawson, Keith A., Cárcano, Flavio, Blanchet, Odile, Shuch, Brian, Nepple, Kenneth G., Margue, Gaëlle, Sundi, Debasish, Diver, W. Ryan, Folgueira, Maria A.A.K., van Bokhoven, Adrie, Neffa, Florencia, Brown, Kevin M., Hofmann, Jonathan N., Rhee, Jongeun, Yeager, Meredith, Cole, Nathan R., Hicks, Belynda D., Manning, Michelle R., Hutchinson, Amy A., Rothman, Nathaniel, Huang, Wen-Yi, Linehan, W. Marston, Lori, Adriana, Ferragu, Matthieu, Zidane-Marinnes, Merzouka, Serrano, Sérgio, Magnabosco, Wesley J., BioBank Japan Project Consortium, Vilas, Ana, Decia, Ricardo, Carusso, Florencia, Graham, Laura S., Anderson, Kyra, Bilen, Mehmet A., Arciero, Cletus, Pellegrin, Isabelle, Ricard, Solène, FinnGen, Scelo, Ghislaine, Banks, Rosamonde E., Vasudev, Naveen S., Soomro, Naeem, Stewart, Grant D., Adeyoju, Adebanji, Bromage, Stephen, Hrouda, David, Gibbons, Norma, Patel, Poulam, Sullivan, Mark, Protheroe, Andrew, Nugent, Francesca I., Fournier, Michelle J., Zhang, Xiaoyu, Martin, Lisa J., Komisarenko, Maria, Eisen, Timothy, Cunningham, Sonia A., Connolly, Denise C., Uzzo, Robert G., Zaridze, David, Mukeria, Anush, Holcatova, Ivana, Hornakova, Anna, Foretova, Lenka, Janout, Vladimir, Mates, Dana, Jinga, Viorel, Rascu, Stefan, Mijuskovic, Mirjana, Savic, Slavisa, Milosavljevic, Sasa, Gaborieau, Valérie, Abedi-Ardekani, Behnoush, McKay, James, Johansson, Mattias, Phouthavongsy, Larry, Hayman, Lindsay, Li, Jason, Lungu, Ilinca, Bezerra, Stephania M., de Souza, Aline G., Sares, Claudia T.G., Reis, Rodolfo B., Gallucci, Fabio P., Cordeiro, Mauricio D., Pomerantz, Mark, Lee, Gwo-Shu M., Freedman, Matthew L., Jeong, Anhyo, Greenberg, Samantha E., Sanchez, Alejandro, Thompson, R. Houston, Sharma, Vidit, Thiel, David D., Ball, Colleen T., Abreu, Diego, Lam, Elaine T., Nahas, William C., Master, Viraj A., Patel, Alpa V., Bernhard, Jean-Christophe, Freedman, Neal D., Bigot, Pierre, Reis, Rui M., Colli, Leandro M., Finelli, Antonio, Manley, Brandon J., Terao, Chikashi, Choueiri, Toni K., Carraro, Dirce M., Houlston, Richard, Eckel-Passow, Jeanette E., Abbosh, Philip H., Ganna, Andrea, Brennan, Paul, Gu, Jian, Chanock, Stephen J., Guo, Xinyu, Winter, Timothy D., Jahagirdar, Om, Ha, Eunji, and Susztak, Katalin
- Published
- 2024
- Full Text
- View/download PDF
5. Adding 6 months of androgen deprivation therapy to postoperative radiotherapy for prostate cancer: a comparison of short-course versus no androgen deprivation therapy in the RADICALS-HD randomised controlled trial
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Amos, Claire, Beaney, Katherine, Bellenger, Katharine, Brawley, Chris, Chung, Christina, Cook, Adrian, Embleton, Andrew, Forcat, Silvia, Goldstein, Cindy, Grabey, Jenna, Hague, Dominic, Herasimtschuk, Anna, Islam, Zaheer, Jovic, Gordana, Maniatis, Christos, Masters, Lindsey, Mohamed, Fatima, Morgan, Rachel, Murphy, Claire, Noor, Dipa, Parmar, Max, Patterson, Paul, Pickering, Holly, Pugh, Cheryl, Rauchenberger, Mary, Ribeiro, Helena, Roach, Carol, Seray-Wurie, Fatimah, Shaji, Preetha, Sims, Hannah, Spittle, Ben, Sydes, Matthew, Tappenden, Nancy, Tsang, Lilian, Uscinska, Barbara, Brown, Teddy, Casey, Sue, Davidson, Cathy, Dellar, Conor, Fletcher, Mandy, Meyer, Ralph, Murphy, Karen, Parulekar, Wendy, Richardson, Harriet, Richardson, Karen, Whelan, Kate, Bissett, Donald, Bonner-Shand, Shelagh, Grant, Judith, Lynch, Rory, MacDonald, Graham, McWilliam, Marie, Moir, Rachel, Rodwell, Sue, Shearer, Kirsty, Smith, Margaret, Binns, Louise, Briggs, Maxine, Brown, Simon, Casanova, Nathalie, Clark, Katy, Hartley, Jasmine, Henry, Ann, Henson, Helen, Hill, Pipa, Jeyasanger, Ganesan, McAlister, Judy, Parkinson, Sharron, Shaw, Alison, Alcock, Christopher, Brady, Joanne, Camilleri, Philip, Carpenter, Janice, Hogbin, Emma, Hyde, Katherine, Kavanagh, Roisin, Ngumo, Alice, Padilla-Harris, Cheryl, Panakis, Niki, Pwint, Thinn, Sabharwal, Ami, Stammers, Tracey, Stone, Helena, Varley, Gail, Weaver, Andrew, Wynn, Hazel, Allan, Elaine, Ansari, Jawaher, Cannon, Philip, Carruthers, Ross, Coubrough, Claudia, Cowan, Chloe, Glen, Hilary, Graham, Janet, Hardie, Maryon, Love, Clare, Macleod, Nicholas, Mahmood, Rana, McClements, Jane, McGlynn, Brian, McKernan, Margaret, Mcleod, Nick, Othman, Aqilah, Ross, Kristy, Roxburgh, Patricia, Templeton, Maureen, Tufail, Aisha, Turley, Claudia, Wilson, Mark, Ali, Zulfiqer, Andrews, Kelly, Burns, Rebecca, Butterworth, Caryl, Coventry, Thomas, Evans, Angela, Jones, Gareth, Lewis, Sion, Oommen, Nikhil, Owen, Susan, Saxton, Wendy, Tapping, Sister Hayley, Thomas, Dianne, Thomas, Rachel, Walker, Beth, Williams, Rachel, Collard, Susan, Ford, Victoria, Goodhind, Frances, Holbrook, Becky, Kershaw, Elizabeth, Ley, Samantha, Martinez, Maria, McCormack, Anne, Sheehan, Denise, Toy, Elizabeth, Van-Koutrik, Lynne, Varughese, Mohini, Aitken, Katherine, Barlow, David, Beattie, Louise, Bownie-Mukumbu, Godfrey, Bryan, Rachel, Corner, Victoria, Edwards, Abigail, Fazekasne Fulep, Adrienn, Guerrero-Urbano, Teresa, Gwilt, Julie, Happle, Liz, Jackman, Dee, Krysta, Beata, Paisey, Sangeeta, Shaffer, Richard, Smith, Jackie, Westley, Rosalyne, Yusof, Hilawati, Appleby, Rowan, Avis, Joanne, Beresford, Mark, Brydon-Hill, Ruth, Cox, Christine, Curtis, Samantha, Elwell, Christine, Frim, Olivera, Hamilton, Beatrice, Hudson, Zoe, Jenner, Abigail, Mantle, Mark, Mason, Jessica, Masson, Susan, McFarlane, Jonathan, Newman, Hugh, Pocock, Abigail, Robertson, Bryony, Tomlinson, Eve, Wassall, Rebecca, Williams (Née Allen), Sister Tania, Brown, Grace, Clarke, Peter, Cole, Aiden, Cousins, Jane, Gilchrist, Gail, Hagan, Chris, Hanna, Emma, Harney, Jackie, Hetherington, Stacey, Houghton, Fionnuala, Hynds, Sharon, Jain, Suneil, Johnston, Ruth, Keane, Patrick, Lyons, Ciara, McAleese, Jonathan, McAllister, Jo, McKenna, Karen, Mitchell, Darren, Murray, Stacey, O'Sullivan, Joe, Rajan, Nambi, Shum, Poh Lin, Stewart, David, Stranex, Stephen, Totten, Grace, Chandrashekara, Madhura, Drew, Ellen, Drew, Mary (Ellen), Fletcher, Julie, Gamble, Tina, Lokes, Rachel, Schumacher, Ann, Shetty, Kavitha, Sohanpal, Sundip, Whitehouse, James, Zarkar, Anjali, Ford, Daniel, Glaholm, John, Lenton, Daniel, O'Beney, Rachael, Taylor, Helen, Thomas, Helen, Chetiyawardana, Samantha, Doherty, A, El-Modir, Ahmed, Gunn, Melanie, James, Nicholas, Kedge, Liz, Mannan, Aliyah, Marange, Josephine, Morrison, Andrew, Okubanjo, Maryanne, Olaniyi-Oduntan, Darlletta, Peterkin, Zhane, Preece, George, Qureshi, Zayn, Ross, Liliam, Samra, Tarandip, Southgate, Elizabeth, Stephens, Rebekah, Stevenson, Robert, Watson-Jones, Phillip, Abdulwahid, Danya, Ainsworth, Sarah, Ashworth, Sue, Beard, Karen, Charnley, Natalie, Desai, Parth, Fielding, Bethany, Flaherty, Jan, Forrest, Diane, Frankland, Helen, Haidar, Imran, Hargreaves, Jeanette, Henry, Joanne, Hugill, Angela, Jewers, Karen, Keith, Sarah, Kilroy, Stephen, King, Jennifer, Parikh, Omi, Riley, Karen, Ryan-Smith, Janet, Thomas, Jacqueline, Thompson, Catherine, Tickle, Vivienne, Waring, Lynsey, Wise, Marcus, Dawson, Louise, Ditchfield, Julie, Al-Samarraie, Amir, Bolger, Annette, Davies, Llinos, Flavin, Aileen, Heron, Jane, Hughes, Faye, Jackson, Kim, Lewis, Joanne, Manley, Rachel, Rutter, Charley-Anne, Smith, Nick, Srinivasan, Vaiku, Stockport, Jane, Thomas, Heather, Toussi, H, Wood, Cathryn, Archer, Simon, Fletcher, Joanne, Ginnelly, Helen, Kirkby, Amy, Knight (n. Sherburn), Victoria, Lawrence nee Palmer, Tara, Mashegede, Beverley, Metcalf, Karen, Panades, Miguel, Sreenivasan, Thiagarajan, Szymiczek, Kinga, Thomas, Isobel, Young, Anita, Broadley, Eve, Brock, Sue, Davies, Joseph, Jones, Stephanie, McCully, Ruby, Naraine, Nicky, Preece, Kate, Purandare, Laura, Rabbi, Taslima, Savage, Sarah, Vamplew, Luke, Bamford, Linda, Benton, Richard, Cotterill, Lauren, Inman, Hayley, Karsera, Louise, Kay, Anne Marie, Kenyon, Lucille, Lazarte, Jannika, McNulty, Dawn, Moore, Eleanor, Nallathambi, Chandran, Naylor, Deirdre, Owen, Lisa, Parikh, Shefali, Pendrill, Amy, Price, Joanne, Robertshaw, Helen, Rodda, Sree, Sewell, Jane, Teo, Mark, Waldron, Eleanor, Bloomfield, David, Blythe, Tracy, Brown, Joanne, Carr, Philippa, Chambers, Carla, Dlodlo, Jessica, Frattaroli, Paul, Gilbert, Duncan, Hart, Andrew, Hodges, Samantha, Hooper, Simon, Hunter, Catherine, Lactao, Ranee, Leitao, Madalena, McKinna, Fiona, Nikapota, Ashok, Peterson, Jane, Robinson, Angus, Tremlett, Jean, Webb, Andrew, Wilkins, Marie, Young, Bobbie, Bahl, Amit, Baxter, Matt, Bowers, Dawn, Challipalli, Amarnath, Coe, Marc, Cowley, Sue, Gillatt, David, Griffiths, Dorothy, Henson (nee Savidge), Verity, Hilman, Serena, Hollister, Robert, Kisanga, Mary, Lee, Vivienne, Lowe, Amelia, Macefield, Rhiannon, Pegler, Ruth, Robertson, Peter, Saldanha, Helen, Simmonds, Mary, Sims, Laura, Wheeler, Lucie, Wilson, Paula, Woods, Martin, Yarrow, Sue, Zelley, Sarah, Abd Alazeez, Mohamed, Alderton, Kate, Brain, Carol, Chilcott, Helen, Clarke, Samantha, Cobos-Arrivabene, Marta, Corderoy, Helen, Cousins, Rebecca, Garner, Victoria, Herbert, Chris, Johnson, Lyndsey, Jones, Kathryn, Kemp, Gail, Kirkby, Sarah, Kirkpatrick, Suriya, Koupparis, Anthony, Manning, Courtney, Oxley, Jon, Perry, Emily, Persad, Raj, Phipps, Charlotte, Richmond-Russell, Kerry, Rowe, Edward, Shelton, Luke, Shiridzinomwa, Constance, Smith, Carolyn, Treasure, Ann, Wyatt, Clare, Beesley, Katherine, Benson, Richard, Couch, Ellie, Foxwell, Sue, Goss, Vanessa, Harnwell, Juliette, Hughes-Davies, Luke, Joslin, Vicky, Laubscher, Angelique, Mazhar, Danish, Patterson, Helen, Raj, Sanjay, Ramanujachar, Ramya, Rimmer, Yvonne, Robinson, Nicola, Russell, Simon, Stone, Matthew, Thomas, Robert, Treeby, Jo, Vickery, Kathryn, Woodward, Cathryn, Ahmed, Ilyas, Appleby, Bonny, Brulinski, Patryk, Buckley, Julie, Catt, Natalie, Coppins, Helen, Crawford, Sister Denise, Davies, Julie-Ann, Drakeley, Susan, Edwards, Albert, Evans, Clary, Galante, Joao, Gladwell, Louise, Gough, Jessica, Hargreaves, Carolyn, Hegarty, Gemma, Kehoe, Laura, Larkins, Rachel, Lipsham, Margaret, Little, Jessica, Malde, Rohit, Middleton, Sharon, Mikropoulos, Christos, Mirza, Arafat, Mithal, Natasha, Nathan, Kannon, Raman, Rakesh, Rendall, Alice, Robinson, Karen, Ryan, Rachel, Sim, Van, Swann, Michelle, Tasker, Lorraine, Taylor, Katy, Thomas, Carys, Trigonis, Ioannis, Walker, Karen, Williams, Joanne, Williamson, Elizabeth, Wood, Marian, Wood, Pauline, Zurakovsky, Hilary, Bois (nee Harris), Elizabeth, Chan, Hin Fan, Chikopela, Loveness, Clark, Helen, Clements, Colette, Holliday, Samantha, Hughes, Owen, Jones, Clare, Kynaston, Howard, Mason, Malcolm, Narahari, Krishna, Pearse, Kevin, Staffurth, John, Austin, Mandy, Barnett, Christian, Camburn, Sister Tracey, Dawson, Elizabeth, Gibson, Sian, Hamid, Abdel, Kancherla, Kiran, Leone, Priscilla, Perkins, Lauren, Ramsay, Valerie, Singizi, Bryan, Allen, Julie, Anderson, Susan, Andrews (nee Moore), Eleanor, Bakawala, Rehana, Beazer, Sarah, Binks, Colin, Bowen, Jo, Broomfield, Barbara, Cook, Audrey, Crossley, Lin, Ford, Chris, Forkes, Janet, Hall, Julia, Healey-Mariano, Jennifer, Jenkins, Peter, Johnson, Nigel, Jonnada, Sai, Owen, Roger, Pratten, Elaine, Sayers, Rachel, Shimell, Chris, Skelton, Amy, Tan, Matthew, Trigg-Hogarth, Kate, Wronski, Sue, Aldous, Mary, Archer, Denise, Eccleson, Helen, Gallimore, Elizabeth, Green, Sue, Ibrahim, Azman, Jones, Carys, Prince, Jude, Chrystal, Melanie, Din, Omar, Firth, Alexandra, Ford, Nicky, Kirkbride, Peter, Martindale, John, Redfearn, Alison, Smedley (nee McCabe), Janine, Smith, Lucy, Sorice, Vittoria, Stevenson, Lesley, Toms, Julie, Wood, Sister Kim, Barke, Nyssa, Basu, Devy, Dewar, Lorna, Driscoll, Celine, Hunting, Liz, Kumar, Muthar, Mabelin, Louies, Sizer, Bruce, Thorogood, Lucy, Askew, Sarah, Beech, Darren, Broom, Jane, Duley, Emma, Firth, Elizabeth, Gould, Aaron, Hocking, Christopher, Johns, Louise, Kent, Emma, Madine, John, Partridge, Kerena, Penhaligon, Corrine, Pentecost, Catherine, Pollard, Kay, Poultney, Melissa, Pynsent, William, Skewes, Johanna, Steele, Anita, Thomson, Alastair H, Topps, Alice, Townley, Luke, Wheatley, Duncan, Brown, Maggie, Chan, Andrew, Connor, Marie, Elwell, Sue, Geraghty, Kerry, Griffiths, Theresa, Hayward, Lesley, Humber, Caroline, Khan, Yakhub, Lake, Sister Judith, Laverick, Rosaleen, Mansell, Gemma, Mislang, Albert, Ngwenya, Su, Panesar, Pritpal, Sanders, Kay, Simmons, Elaine, Sinfield, Melanie, Stanley, Laura, Steventon, Emily, Stockdale, Andrew, Sunny, Manju, Thind, Manreet, Tranter, Fiona, Tsalic, Medy, Worlding, Jane, Adamson, Vanessa, Bennion, Carole, Butler-Barnes, Jenny, Hough, Adele, Hough, Chris, Hughes, Joanne, Irwin, P, Javle, P, Logue, John, Mansfield, Carolyn, Smith, Rachel, Sumner, Lesley, Tomlinson, Annabel, Tran, Anna, Walker, Caroline, Wylie, James, Chakraborti, Prabir, Das, Prantik, Ennis, Dawn, Marriott, Sue, Muthukumar, Dakshinamoorthy, Pattu, Pugazhenthi, Ward, Colin, Alzouebi, Mymoona, Burlace, Barbara, Ferguson, Catherine, Hooton, Georgia, Jeffcutt, Nicole, Neal, Amy, Pezaro, Carmel, Sivoglo, Virgil, Taylor, Jennifer, Wilkinson, Nicola, Afzal, Naveed, Anderson, Beverley, Andrews, Stephen, Bakker, Piet, Breakspear, Sally, Cornaby, Andrew, Crellin, Perric, Gibbins, Andrew, Gibbins, Jackie, Glen, Tracy, Goodsell, Josie, Horton, Sarah, Love, Sally, Masters, Benjamin, Rees, Andrew, Sharpe, Simon, Taylor, Kate, Wignall, Suzy, Harrow, Sister Kath, Jones, Lesley, Kanyi, Karen, Keng-Koh, Pek, McGarry, Karen, Ramachandra, Prakash, Watts, Angela, Baumber, Shelley, Howard, Joanna, Jones-Skipper, Kay, Manetta, Caroline, McCrisken, Lauren, Taylor, Jo-Anne, Williams, Amanda, Clark, Alison, Clarke, Maria, Egan, Lisa, Fiddes, Kathleen, Forman, Susan, Gardiner, Fiona, Jeffrey, David, Mariappan, Param, Mayne, Barbara, McLaren, Duncan, Rogers, Brian, Woods, Catherine, Young, Douglas, Anderson, John, Baines, Kizzy, Crundwell, M, Davey, Elizabeth, Lawless, Theresa, Matkins, Ellen, McGinley, Shannon, McGrath, John, Piper, Jane, Roantree, Alison, Seath, Ingrid, Srinivasan, Rajaguru, Stott, Mark, Timmings, Katie, Webb, Claire, Al-hasso, Abdulla, Barwell, Lorraine, Dodds, David, Finnegan, Niall, Griffen, Ailsa, Jones, Rob, Lawless, Claire, MacMillan, Antonia, Russell, Martin, Sadozye, Azmat, Shirley, Sian, Sidek, Norma, Wallace, Jan, Akhtar, Naeem, Bell, Karen, Humpreys, Louise, McWilliam, Donna, Moody, Emma, O'Neil, Rebecca, Peck, Suzannah, Auladin, Raidah, Bird, Stephanie, Bissa, Caterina, Dabbs, Marianne, Di Maria, Fabio, Goh, Chee, Harding, Joshua, Jamieson, Ceri, Jones, Jules, Khaksar, Sara, Laing, Robert, Matthews, Laura, Medisetti, Aruna, Molony-Oates, Barbara, Money-Kyrle, Julian, Nobes, Jenny, Rabsztyn, Weronika, Sidi, Frances, Smale, Daisy May, Stone, Sarah, Tindall, Annie, Woods, Jane, Wu, Min, Daniel, Amelia, Holmes, Evelyn, Kellaway, Joanne, Lewis, Amanda, Light, Teresa, Melcher, Lucinda, Robinson, Lily, Staines, Nikki, Carini, Serrafina, Cooper, Sophie, Evans, Melanie, Follows, Josh, Grant, Warren, Hedges, Andy, Hughes, Claire, Jones (Birch), Janine, King, Lisa, Lees, Laura, Mercer, Lily, Myles, Sophie, Roberts, Zara, Williamson, Nicola, Abbassi, Sara, Alonzi, Roberto, Anyamene, Nicola, Bici, Julia, Collins, Lucy, Dickson, Jeanette, Garrido-Perez, Sandra, Hoskin, Peter, Hughes, Robert, Jenkins, Suzanne, Kowalewska, Paulina, Milner, Jessica, Mitchell, Lesley, Ostler, Peter, Rashid, Aamna, Stapleton, Stephanie, Bashir, Faheem, Bone, Linzi, Clark, Diane, Dixit, Sanjay, Horne, Rhian, Jones, Dawn, Palmer, Sarah, Plowman, Kristian, Rawlings, Julie, Simms, Matthew, Addison, Anglise, Arnott, Seonaid, Borgaonkar, Sudhir, Brown, Sandra, Campbell, Audrey, Colligan, Steve, Cormack, Margaret, Doughty, Victoria, Kelly, Kay, Lister, Debbie, Macdonald, Alison, Macgregor, Carol, Mackay, Rachel, Madeleine, Jude, McNally, Morag, McPhail, Neil, Neville, Sean, Nicholls, Alison, Papakostidi, Aristoula, Simpson, Georgina, Sinclair, Glenda, Skene, Anna, Telfer, Sheena, Urquhart, Zoe, Whillis, David, Etheridge, Charlotte, Ford, Amanda, Ridley, Paul, Scrase, Christopher, Upson, Susan, Venkitaraman, Ramachandran, Capaldi, Lisa, Churn, Mark, Higgins, Linda, Knott, Helen, Stringer (pr. Davis), Sally, Taylor, Jacob, Tranter, Helen, Wollaston, Julie, Brogan (nee Roddie), Stephanie, Erskine, Susan, Hamill, Maureen, Prentice, Lynn, Symon, Lesley, Teahan, Seamus, Todd, Anne, Tweedle, James, Young, Sally, Austin (nee Glover), Gemma, Boon, Ian, Bottomley, David, Breckin, Edmund, Clarke, Jude, Coyle, Catherine, Davies, Emily, Goulding, James, Kiltie, Anne, Loughrey, Carmel, Murad, Fatima, Pratt, Claire, Shuttleworth, Pam, Smith, Beccy, Smith, Gill, Branson (née Dineen), Amy, Christmas, Sallyanne, Cooke, Jill, Griffiths, Leyshon, Kent, Christopher, King, Amy, Kockelbergh, Roger, Potterton, Janet, Speed, Lesley, Vasanthan, Subramanian, Walker, Julia, Baria, Karin, Bateman, Samantha, Coombs, Sarah, Cunningham, Amy, Dahar, Nazeer, Daruwala, Pallon, Francis, Olesya, Hall, Jane, Hoare, Kathryn, Key, Claire, Lockwood, Carol, Mark, Ian, Newton, Rachel, Sloan, Andrew, Bermingham, Nicola, Dean, Lynsey, Malik, Zafar, Pilkington, Pauline, Robson, Peter, Rogers, Heather, Rogers, Thomas, Treherne, Katy, Bourke, Amie, Chikkamuniyappa, Bindu, Dalton-Short, Ross, Edwards, Steve, Falconer, Alison, Ford, Amy, Harinarayanan, Sathish, Hassan, Nebah, Hornzee, Gillian, Magwaro, Sophia, McInerney, Sue, Pratap, Bhavesh, Rezkallah, Sarah, Sadare (Olaleye), Ibiyemi, Stancliffe, May, Stewart, Simon, Thoi, Anne-Maree, Westrop, Anna, Ahamadali, Sheefa, Arsanious, Nasr, Balogun, Shaki, Batish, Cheryl, Campbell, Yvonne, Crowley, Claire, Dunne, Emma, Ferreira, Miguel, Haldeos, Anne, Hijab, Adham, Huddart, Robert, John, Babbin, Michaelidou, Andriana, Nawrozzadeh, Mohammed, Pach, Jackie, Patel, Priyanka, Payne, Ann, Perry, Matthew, Serra, Maria, Springall, Christine, Thompson, Jane, Thomson, Sister Jane, Tree, Alison, Aya, Viviana, Beaney, Ronald, Bower, Lorna, Conway, Lisa-Jane, Donaghey, Sally, Gordon, Hussain, Grau, Isabel, Harris, Sarah, Hogan, Vesna, Hore, Brendan, Hughes, Simon, Jones, Katie, Kuenzig, Greg, Morris, Stephen, Nunney, Dawn, Rashid, Jessica, Reynolds, Philip, Rooprai, Bali, Mangar, Stephen, Azirar, Hanna, Caumont, Tom, Gupta, Nishi, Hill, Judy, Karp, Stephen, Kullane, Sagal, Macavoy, Tina, Neave, Farhad, Newby, Jackie, Van Someren, Chloe, Anderson, Naomi, Annan, Lynda, Cooke, Juniebel, Douch, Emma, Fawcitt, Sara, Gore, Alexandra, Grieve, Sylvia, Jarvis, Claire, McCadden, Angela, Needleman, Sarah, Pigott, Katherine, Powell, Hannah, Ramtohul, Kaliyanee, Rosenfelder, Nicola, Vilarino-Varela, Maria, Ali, Jennyfa, Ali, Maryam, Banda, Laillah-Crystal, Bott, Trevor, Brown, Emmanuel, Bryant, Hanna, Carlino, Giulia, Grant, Cordelia, Hogan, Holly, Khoo, Vincent, Mojidra, Chintan, Montebello, Joseph, Morrison, Jennifer, Olabanji, Matthew, Pillai, Sijy, Siu, Bernard, Stafferton, Ruth, Storrs, Sarah, Townsend-Thorn, Debra, Van As, Nicholas, Vijayakumar, Vijitha, Welsh, Liam, Dearnaley, David, Gao, Annie, Horwich, Alan, Lewington, Val, Marshall, John, Murphy, Louise, Parker, Chris, Beaton, Kirsty, Bech-Nielsen, Nanette, Bolton, Olivia, Conibear, John, Dekaj, Fatjon, Hillman, Paul, Jayachandran, Resmi, Kaliski, Alexandre, Kiff, Janet, Nicholson, Alastair, Nixon, Jude, Oladimeji, Janet, Riches, Oscar, Smith, Dan, Tipples, Karen, Wells, Paula, Anderson, Chris, Daly, Deirdre, Dover, Serena, Gilmartin, Claire, Golden, Sophie, Gregg, Jane, Issa, Rami, Oni, Titilayo, Patel, Chandni, Quarrell, Mark, Rolfe, Debbie, Tighe, Helen, Toledo, Jesusa, Tuazon, Juel, Varro, Robert, Bohra, Vikram, Caballes, Mark, Custins, Laura, Ivie, Stephanie, Joshi, Manisha, Liau, Joy, Naim, Farhan, Patel, Anup, Pathmanathan, Byiravey, Russell, Emily, Tippins, Anna, Agdiran, Didem, Aggarwal, Ajay, Amoaten, Thomas, Aslam, Natasha, Bonsu, Nicole, Butt, Zainab, Danaswamy, Patricia, Davda, Reena, Gillesen, Annelies, Goel, Roshni, Khong, Rachel, Lowi, Suzy, Merrick, Richard, Mitra, Anita, Payne, Heather, Teh, Jonathan, Whinn, Samantha, Woolf, David, Zilkha, Helene, Dawson-Athey, Linda, Foster, Emma, Gillian, Andrew, Green, James, Hines, John, Holden, Simon, Kazingizi, Memory, O'Neill, John, Olaoni, Thompson, Peters, John, Philp, Timothy, Zaidi, Sadaf, Adeyoju, Adebanji, Adinkra, Victoria, Brough, Richard, Brown, Stephen CW, Collins, Gerald, Hardstaff, Lisa, Hill, Pippa, Kujawa, Magda, McCurrie, Marilyn, Townley, Barbara, Woodhouse, Iain, Zafar, Waheed, Beesley, Sharon, Breen, Vivienne, Burrage, Su, Calvert, Clare, Davison, Alison, Dias, Heather, Fossey, Gavin, Hotine, Jodie, Jones, Ifan, Jope, Carmel, Lines, Yvonne, Martins, Sarah, Mercier, Barbara, Murray, Jane, Neshiri, Innocent, Pamphlett, Ian, Phillips, Ann, Rai, Pavnish, Roberts, Verity, Taylor, Henry, Tribe, Lisa, Bottomley, Ian, Buchan, Jonathan, Carpio, Viviana, Choudhury, Ananya, Conroy, Ruth, Cowan, Richard, Davison, Sue, Duncan, Ian, Elliott, Tony, Fair, Kim, Fallaize, Adrian, Flanagan, Laura, Green, Sarah, Harris, Catherine, Hart, Amber, Jones, Cathryn, Livsey, Jacqueline, McCaul, Damian, Nazari, Roonak, Newbery, Carol, O'Connor, Kate, O'Dwyer, Sister Jackie, Oliver, Joanne, Onoge, Ekugbe, Petsa, Maria, Redshaw, Catherine, Smith, Sarah-Ellen, Spoor, Willemijn, Thomas, Sister Viv, White, Holly, Worsley, Lucy, Bailey, Linda, Bennett, Molly, Corless, Rebecca, Duffy, Annie, Fellows, Kathryn, Gipson, Anna, Haydock, Helen, Knox, WF, Liptrott, Sarah, McCarth, Fiona, McCartin, Fiona, Mistry, Heena, Mthethwa, Thobekile, Partington, Lillian, Piper, Lindsay, Ramani, Vijay, Sahin, Sarah, Sangar, Vijay, Slevin, Kathryn, Tuck, Jonathan, Atkinson, Lorraine, Barnbrooke, Sarah, Barnes, Alison, Brownless, Caroline, Chadwick, David, Hardman, John, Harland, Keith, Long, Carol, McAuliffe, Sarah, McBride, Julia, McClurey, Sister Patricia, Mohan, Rita, Naylor, Lynne, Peedell, Clive, Robson, Paula, Shakespeare, Devadasan, Thompson, Emma, Van der Voet, Hans, Wilson, David, Barron, Chris, Frew, John, Lambert, Katy, McMenemin, Rhona, Pedley, Ian, Riseborough, Danielle, Roberts, Trevor, Stockley, Emma, Stoddart, Jonathan, Tate, Janine, Walker, Jayashree, Workman, Bridget, Barnett, Debra, Carter, Adam, Cox, Adam, Davey, Alison, Davies, Kirstin, Gilby, Lisa, Hodge, Simon, Kearney, S, Lavender, Helene, Marty, Janet, Nash, Maxine, Rahman, Syhed, Richards, Jayne, Simpson, Julie, Wall, Elaine, Webb, Paula, Wild, Karen, Wilson, Jim, Branagan, Jenny, Dell, Gillian, Foo, Maxine, Goyena, Ruby, Jones, Andrea, McBain, Hazel, McGrath, Katherine, O'Callaghan, Jane, Ramanathan, Dorai, Tee, Elizabeth, Thominson, Bronwen, Tighe (nee Bussey), Rachel, Beety, Jane, Birch, Richard, Bloomfield, Mark, Callam, Sara, Cooper, Adele, Darby, Helen, Healey, Gail, Heasley, Karen, Kapur, Guarav, London, Clare, Oosterom, Katrien, Ostrowski, Joe, Shobrook, Bridget, Turner, Sarah, Wade, Rob, Walker, Suzanne, Walton, Sharon, Websdale, Cheryl, White, Joanna, Alder, Leanne, Chivers, Rachael, Gooch, Carol, Howard, Lucy, Hutchinson, Camille, Jevons, Cody, Kumar, Daniel, Marley, Hazel, Mills, Jamie, Purves, Hanna, Sayers, Ian, Sundar, Santhanam, Szolin-Jones, Jacob, Walker, Georgina, Wood, Catherine, Cook, Wendy, Gill, Lisa, Johnson, Joanne, Johnstone, Dawn, Jones, Richard, Mistry, Leena, Scarratt, Lyndsay, Aiku, Abimbola, Ajzensztejn, Daniel, Al-Chamali, Hiba, Andrade, Gerard, Barber, Dave, Bekulart, Sylwia, Bhatnagar, Gagan, Boutflower, Jane, Brewster, Simon, Butterfield, Anne, Carroll, Weronika, Cole, David J, Coutts, Tim, Doyle, Kerrie, Durrant, Lisa, Green, Trish, Jampana, Raj, Jastrzebska, Patrycja, Kyffin, Phillippa, Langridge, Nicole, Lawrey, Sarah, Markus, Sarah, Marston, Kerrie, Mooney, Matthew, Mukkath, Sandra, Murphy, Ann, Owens, Rob, Ruane, Sarah, Sabbagh, Ahmad, Samkange, Grace, Sankighatta, Naveen, Skwarski, Michael, Stuart, Robert, Wellman, Sandie, Wilson, Jo, Cavanagh, Kerrie, Hollingdale, Abigail, Allen, Susan, Barter, Elisa, Gregory, Debbie, Ingle, Charlotte, Lawrence, Steph, Rooney, Paula-Joanne, Bishop, Emma, Brennan, Maria, Cogley, Lyn, Hammonds, John Christopher, McInerney, Paul, McLarty, Esther, Natale, Salvatore, Pascoe, Sarah, Purcell, Keith, Sells, Henry, Tyner, Sharah, yates, Victoria, Beamish, Neal, Blaney, Hilary, Clapp, Felicity, Clarke, Elizabeth, Coffin, Teresa, Davies, Joe, Downs, Nichola, Gillespie, Sally, Heckford, Louise, Iskender, Amanda, Orford, Sara, Pressdee, Sandy, Rix, Sophie, Wheelwright, Roger, Woodward, Elizabeth, Wright, Seonaid, Blight, Kathy, Dobson, Tracey, Hale, Jennifer, Harris-Burland, Angie, Khoury, Ghassan, Madhava, Kudingila, Meadows, Lorna, Nagar, Yoodhvir, Roca, Mila, Stacey, Wendy, Stephenson, Anna, Uherek, Maja, Virgo, Azarel, Watkinson, Catrin, Birtle, Alison, Chauhan, Zainab, Cornthwaite, Stephanie, Curtis, Sandra, Ellard, Rose, Fish, Nathan, Hefferon, Billy, Searle, Claire, Spickett, Helen, Walmsley, Catherine, Atkinson, Jane, Brown, Richard B, Cartwright, Debbie, Coomber, Kristy, Hunt, Allison, Kowalczyk-Williams, Wioletta, Lewis, Christina, Parr, Stephen, Purdon, Helen, Rogers, Paul, Vowell, Emma, Featherstone, Wendy, Hamilton, Joanna, Harrison, Alison, Hindle, Margaret, Hodson, Hayley, Isaew, Andrea, Knapp, Jeanette, Moss, Sarah, Gibbs, Stephanie, Gujral, Sandeep, Jannapureddy, Revanth, Kelkar, Anand, Martinou, Maria, Mills-Baldock, Tina, O'Brien, Neale, Subramaniam, Ramachandran, Tahir, Saad, Vandal, Mohammad Tanvir, Vu, Thi, Allen, Rachael, Betts, Chris, Bowmer, Amanda, Clarke, Noel, Cordwell, Amanda, Dharmaprasad, Soney, Duncan (nee Keatley), Claire, Farnworth, Christine, Farrell, Helen, George, Siny, Goulden, Kay, Harter, Leah, Kaushal, Malan, Kirk, Sister Sarah, Lau, Maurice, Lydon, Anne Marie, O'Flynn, Kieran, Platt, Danielle, Shackley, David, Stevenson, Garry, Taylor, Sister Melanie, Thompson, Chloe-Anne, Vinod, Cellins, Wadsworth, Oliver, Youd, Sister Jill, Attlee, Julie, Bhatnagar, Adityanarayan, Bunn, Sarah, Campbell, Allister, El-Saghir, Mohammed, Fennelly, Ruth, Guy, Peter, Mattocks, Lehentha, Mcintosh, Gregor, Murphy, Brenda, Reed, Catherine, Strong-Sheldrake, Sophia, Tedd, Gemma, Dent, Kathleen, Hood, Marion, Martin, Karen, Pearson, Sandra, Potoczna, Dorota, Spencer, Sue, Towse, Jo, Whotton, Nikita, Bowen, Katie, Clark, Su, Clarke, Rachael, Gibbins, Kate, Martin, Jackie, Smith, Suzanne, Spalton, Catherine, Tay, Jessica, Adams, Marion, Bates, Emma, Chennattukungu, Indukala, Clancy, Joanna, Cross, Vanessa, Hughes, Hayley, Jose, Sanal, Kurian-Downer, Sunita, Michael, Elena, Moore, Sister Helen, Nicholas, Karen, Pope, Suzanne, Potts, Sally, Prashant, Ravi, Singh, Harpreet, Smith, Sandra, Srihari, Narayanan, Weaver, Emma, Abbas, Ali, Barnes, Nicky, Dallas, Nicola, Jackson, Sister Ann, Kader, Nicole, Karim, Omer, Laniado, M, Litchfield, Jayne, Mahmood, Sana, O'Donnell, Helen, Robinson, Victoria, Sears, Alison, Sharif, Shahid, Sierra Pala, Ana, Sinclair, Julie-Ann, Smith, Sister Catherine, Ashcroft, Jan, Boardman, John, Bowes-Cavanagh, Jeanette, Brown, Rebecca, Chedham, Alison, Darch, Flora, Farrar, Michelle, Foot, Jayne, Goldsworthy, Simon, Graham, John, Gray, Emma, Green, Sara, Jelski, Joseph, Kalejaiye, Odunayo, Keni, Manjusha, Locke, Angela, Mahoney, Sue, McMeekin, Faith, Periasamy, Manivannan, Russell, Tamlyn, Ruszala, Elizabeth, Segaran, Surayne, Tighe, Mary, Wallbutton, Rebecca, Webster, Christine, Whitcher, Alison, Wiggins, Sarah, Wrigley, Martha, Zietz, Maria, Abab, Julie, Cumming, Kirsty, Galloway, Lucy, Ganabady, Malavika, Haskell, Annelise, Heath, Catherine, James, Naomi, Kennedy, Julie, McFarlane, Victoria, Morales-Azofra, Fabiola, Morton, Susan, Mundy, Carina, Noble, Mark, Paschalis, Alec, Patrick, Julie, Reader, Leanne, Taylor, Lisa, Wakefield, Shauna, Ahmed, Imtiaz, Bowman, Sue, Chan, Olivia, Cyriac, Abby, Davies, Tracey, Maitland, Katrina, Prejbisz, Jan, Reece, Sheila, Shires, Heather, Tsang, David, Anscombe, Eleanor, Brough, WA, Clitheroe, Pat, Cocks, Tracie, Connolly nee McKenna, Sarah, Corcoran, Sam, Coughlan, Tricia, Gilmour, Christina, Goodwin, Emma, Graham, Susan, Hatimy, Umi, Hodgkinson, Sheila, Kilmartin, John, Orrell, Lucy, Rotherham, Carol, Smallwood, Sarah, Taylor, Jill, Wiss, Elliott, Adab, Fawzi, Bhana, Rajanee, Dhinakaran, Kathirvelu, Evans, Marion, Myatt, Alison, Parkinson, Katrina, Peake, Angela, Sellars, Elizabeth, Smith, Rowena, Storer, Julie, Thomasson, Georgia, Vengalil, Salil, Walton, Jenny, Ward, Angela, Boam, Samantha, Burgoyne, Jamie-Rae, Chadwick, Eliot, Gill, Shafiq, Haigh, Steve, Hollis, Keri, Lim, Jun, McCabe, Alastair, Munson, Lyndsey, Nash, Dominic, Saunders, Daniel, Smith, Susan, Wade, Lynne, Evans, Elizabeth, Franklin, Alex, Harris (n. Marchant), Emily, Johnstone, Maria, Jones, Lewis, Lemon, Nicola, Phan, Mau-Don, Pudney, Delia, Spence, Rachael, Stretch, Alison, Tait, Ellen, Williams, Bethan, Belcher, Rebecca, De Silva-Minor, Shiroma, Dodge, Sister Jan, Grayland, Sarah, Jones, Ania, Khan, Omar, Owen, Tim, Palmer, Debbie, Parajes, Cerila, Pegler, Suzannah, Poole, Abbie, Sargent, Sister Tracey, Starling, Ellen, Taylor, Becky, Winter, Sister Helen, Zinyemba, Vivian, Allison, Michele, Blundell, Martyn, Brookman, Catherine, Buckley, Jon, Chamberlain, Shelley, Cuffe, Donna, Davies, Stacey, Fairfax, Claire, Greedus, Helen, Griffin, Hannah, Koehler, Ingrid, Lydon, Anna, Michels, Jorg, Pym, Julia, Roberts, Fiona, Thornton, Lorraine, Vandecandalaere, Elaine, Watts, Erica, Welsh, Linda, Anderson, Jim, Anderson, Juliette, Ball, Julie, Benton, Louise, Bowers, Richard, Chahal, Rohit, Dickinson, Peter, Fosker, Chris, Heeley, Janine, Kanaga-Sundaram, Subramanian, Littler, Stephen, Slack, Jonathan, Sundaram, Subramanian Kanaga, Taylor, Beverley, Weston, Philip, Chettle, Judith, Hartwell, Lyn, Johnson-Rollings, Ashley, Jones, Julia, Millage, Helen, O'Neill, Eilish, Walsh, Donna, Webb, Kerrie, Williams, Jo, Dymond, Harvey, Eleftheriadis, Symeon, Lloyd-Jones, Hugh, Wells, Tom, Bennett, Sarah, Dunn, Sharon, Fildes, Diane, Hassall, Alison, Herbert, Gaynor, Hughes, Kathryn, Innes, Helen, Kelly, Alison, Littler, John, Lomax, Laurie, Miller, Nikki, Nutman, Chris, Stott, Matthew, Syndikus, Isabel, Tolan, Shaun, Weston, Alison, Baker, Ivanna, Carter, Vanda, Chatfield, Jenny, Cooke, Peter, Grant, Anna, Homer, David, Kirk, Christine, Lomas, Claire, McCormick, Marian, Mohseeni, Arizoo, Pawaroo, Renita, Radford, Liz, Rogers, Jason, Samanci, Ali, Sharman, Emma, Spencer, Hazel, Spruce, Debbie, Worthington, Hannah, Bak, Dagmara, Cleary, Kristy, Davies, Sue, Gauntlett, Monica, Gupta, Kamalnayan, Holdsworth, Amanda, Ledger, Kate, Morrow, Hugh, Perry, Heather, Rimell, Patricia, Rosoman, Alison, Tyler, Jayne, White, Ann, Crowe (nee Hughes), Dawn, Flynn-Batham, Marian, Folkes, Linda, Funnell, Sarah, Gilbert, Jeanette, Gomez-Marcos, Raquel, Gonzalez, Celia, Hoskins, Chloe, Moore, Sally, Plataniotis, George, Rippin, Sarah, Smith, Matthew, Tsawayo, Tan, Turner, Nikki, Wakelen, Paula, Cserbane, Anita, Fernandez, Claire, Kurup, Rahul, Manyangadze, Sarah, McLain-Smith, Susan, Protheroe, Andrew, Trewsmith, Neil, Allison, Joanna, Barron, Claire, Beaumont, Erica, Beer, Nigel, Beesley, Kate, Donaldson, David, Duckett, Tracey, Fox, Shirley, Kotze, Michelle, Kumar, Shiyam, Macrory, Joanne, Perry, Jess, Pippard, Lucy, Porter, Tim, Rennie, Kerry, Sparrow, Geoffrey, Williams-Yesson, Barbara, Balderson, Jane, Bowling, Lorna, Brittain, Paul, Brookes, Claire, Campbell, Hilary, Campos, Monica, Conway, Rachel, Davies, Flor, Donnison, Michelle, Elliott, Mark, Evans, Richard, Fallah, Fereshteh, Fearnley, Mark, Giddings, Emma, Gollapothu, Srilakshmi, Harvey, Sally, Holbrook, Andy, Ingham, Jo, Jakeman, Christine, Joseph, Joji, Mole, Lisa, Musunuru, Hima Bindu, Pashley, Sarah, Saleem, Shamila, Stower, Michael, Strider, Paula, Taylor, Carol, Thackray, Louis, Todd, Joanna, Wightman, John, Wilson, Russ, Youngs, Nora, Byrne, Mary Marg, Deenihan, Emma, Durkan, Garret, Jennings, Marian, Mahoney, Catriona, Martin, Joseph, McInerney, Veronica, Raftery, Liz, Rogers, Eamonn, Spillane, Maria, Sullivan, Frank, Teh, Chiaw Woon, Wright, Ann, Harving, Niels, Hejlesen, Finn, Kempel, Mette Moe, Steffensen, Kirsten, Bentzen, Lise, Borre, Michael, Buus, Simon, Fode, Kirsten, Kaa Bach, Birgit, Lassen, Yasmin, Laursen, Vibeke, Lemng Kruse, Helle, Lucakova, Slavka, Nørmark Iversen, Helle, Brasso, Klaus, Christensen, Anne Juel, Gruschy, Lisa, Klovgaard, Karina, Lunau, Anne Sofie, Meidhal Petersen, Peter, Moller Christensen, Trine, Poder, Lone Lund, Ribers, Kristine, Stilling, Sine, Thim, Stine, Torin Lehmann, Anna, Vandborg, Maria, Christensen, Tine, Kokholm, Kathrine Friser, Lindberg, Henriette, Nybom, Kirstine, Rønnengart, Eva, Saxe, Charlotte, Baird, Noelle, Braun, Michael W, Cheung, Arthur, Fourt, Monica, Jackson, Cathy, Jepson, Debbie, Johnson, Arlissa, Karvat, Anand, Kwan, Winkle, McIndoe, Sue, Mitchell, Donna, Sandhu, Sandeep, Serpanchy, Rosanne, Wu, Helen, Beausoleil, Rachelle, Crawford, Melanie, DiMarco, Christine, Ding, Ian, Gladwish, Adam, MacIsaac, Patricia, MarshGray, Kimberley, Morton, Gerard, Murphy, Cara, Pascoe, Caitlin, Pokhrel, Sujata, Stevens, Christiaan, Yoon, Frederick, Yu, Jason, Dubey, Arbind, Sivananthan, Gokulan, Bahary, JeanPaul, Barkati, Maroie, Beauchemin, MarieClaude, Benth, Silvine, Carbonaro, Adriana, Delouya, Guila, ElSokhn, Nidale, Frazzi, Alexandra, Lambert, Carole, Lavertu, Sophie, Menard, Cynthia, Pan, Siew Siew, Rousseau, Pierre, Saad, Fred, Taussky, Daniel, Trudel, Diane, Amanie, John Oliver, Batz, Margaret, Borynec, Carol, Danielson, Brita, Garcia, Leni Santiago, Gramlich, Colin, Lang, Monika, Larson, Beverly, Mallett, Debbie, McCrudden, Sylvia, Murtha, Albert, Parker, Shelley, Parliament, Matthew B, Patel, Samir, Pearcey, Robert, Pervez, Nadeem, Rose, Jim, Shewchuk, Caroline, Smith, Carlie, Usmani, Nawaid, Williams, Candra, Yee, Don, AlRashdan, Abdulla, Avery, Alison, Beaton, Heather, Bond, Brittany, BrucePayne, Kim, Burbridge, Susan, Bursey, Kara, Carvery, Lane, Dill, Kendra, Dugas, Stevie, Harding, Claudia, Hodder, June, Hollenhorst, Helmut, Hubley, Lynn, Joseph, Paul K, Little, Erin, MacDonald, Angela, MacIsaac, Kathy, MacVicar, Jennifer, McCracken, Jillian, Moffatt, Emily, Nieforth, Joan, Patil, Nikhilesh, Rijt, Kelsey van der, Roberts, Victoria, Rose, Tina, Rutledge, Robert DH, Salyzyn, Camryn, Simpson, Robin, Sutherland, Donna, Walker, Heather, Wilke, Derek, Yeo, Tanya, Yunace, Lorrie, Zinck, Connie, Bier, Bianca, Bucci, Catherine, Corbett, Thomas B, Dayes, Ian S, Eady, Robin, Gudelis, Susan O, Hill, Elaine, Kinrade, Yvonne, Laughlin, Anne, Lukka, Himu, Makepeace, Barbara, Marshall, Lynn, Nielsen, Linda, Oliverio, Carmela, Patel, Malti Behn, Tsakirdis, Thedoros, Wong, Jason W T, Allen, Kirsten, Bachand, Francois, Carefoot, Layton, Cotts, Shannon, Creelman, Brianna, Crook, Juanita, GeorgeChayka, Danielle, Halperin, Ross, Hartt, Nancy, Hayes, Jill A, Kim, David, Kim, TuongVan, Kronstal, Flo, Lee, Bernard, Lew, Tanya, McClelland, Marie, Opitz, Debbie, Overend, Aldyn, Reed, Melanie, Watson, Michaella, Wilkie, Karen, Winn, Carol, Yanchuk, Janet, Bonner, Scott, Brander, Mike, Brundage, Michael, Carlson, Cindy, Edwards, Jackie, ElKerdawy, Hala, Harpell, Rhonda, Hartman, Carrie, Kalyvas, Maria, KirbyBello, Denise, Kumar, Vikaash, Leach, Deborah, MacVicar, Karen, Mahmud, Aamer, Maize, Christine, Moelker, Yvonne, Murano, Abby, Paul, Nancy, Ross, Ashley, RossSmith, Marleen, Shenfield, Carey, Spencer, Craig, Tennant, Virginia, Vermette, Tracy, Willing, Stephanie, Zaza, Khaled O, Zeltser, Fred, Gearing, Jennifer, Girolametto, Carla, Gopaul, Darindra, Hamilton, Ronald, Hendel, Debra, Janke, Susan, Knackstedt, Jochen, Kuk, Joda, Morrison, MaryBeth, Mumin, Anissa, Nemirov, Stephanie, Rachakonda, Ramana, Shantz, Brenda S, Siddiqui, Atif, Thallury, Sheeba, Ahmad, Belal, Bailey, Laura, Bauman, Glenn, Camara, Mary Jane, Corkery, Danylle, DSouza, David, DiLullo, Elenor, Eichenberger, Lois, Francis, Peggy, Grant, Susan, Gratton, Albert, Gurzanski, Christina, Hare, Jennifer A, Johnson, Craig, Kenny, Shannon, Lock, Michael I, Loughlin, Kate, Mardell, Stephen, Mayer, Heather, Rodrigues, George B, Sax, Lori, Sebborn, Kes, Sexton, Tracy, Venkatesan, Varagur M, tenHaaf, Darlene, Chatelain, AnneMarie, Fortin, Jacqueline, Houle, Stefanie, Khaouam, Nader, Lachance, Nicole, Laliberte, Benoit, Lemaire, Celine, Nguyen, David H A, Sylvestre, Alma, Vavassis, Peter, Yassa, Michael, Adnaan, Jamila, Briand, Wayne, Casey, Linda, Chipman, Penny, Corwin, Charlotte, Duclos, Marie, Faria, Sergio Luiz, Ghoul, Mokhtar, Joncas, MarieClaude, Koulouris, Zoe, Larocque, Stephanie, Lee, Brenda, Olha, Carolynna, Robert, MarieFrance, Sharma, Rajesh, Shenouda, George, Souhami, Luis, Albrecht, Virginia, Froese, Jane, Froude, Nancy, Howitt, Pamela, Iqbal, Fawaad, Kift, Shannon, Koll, Wayne, Li, Audrey, MacGregor, Barbara, Manganaro, Aileen, McKee, Dianne, Mendoza, Edeliza, Mui, Jimmy, Myrehaug, Sten, Singson, Angelina, Slessor, Janet, Somasiri, Ashane, Stevens, Nicole, Berghout, Koralee, Bourque, JeanMarc, Carkner, Amy, E, Choan, Eapen, Libni, Eze, Nancy, Fish, Matt, Haddad, Alain, Hicks, Kimberly, Iordanidi, Elina, Kanji, Femina, Kendal, Wayne S, MacMullin, Lisa, MacRae, Robert M, Malone, Shawn, Morgan, Scott, Nguyen, Julie, OBrien, Anna, Page, Nancy, Perry, Gad A, Reeves, MarieClaude, Roach, Joanne, Sanchez, Maria, Spearman, Mary, Spencer, Patti, Tikoo, Archana, Turriff, Lisa, Wright, Natalie, Bedoya, Luis Diaz de, Cossette, Danielle, Cusan, Leonello, Desrosiers, Isabelle, Dufour, Nathalie, Foster, William, Gomez, JoseLuis, Hathout, Lara, Lajoie, MarieAndree, Martin, AndreGuy, Pouliot, Sophie, Vigneault, Eric, Bouchard, Myriam, Bujold, Rachel, Carmel, Michel, Cote, Genevieve, Dion, Helene, Ebacher, Annie, Gauthier, Isabelle C, Ladouceur, Cynthia, Lamoureux, Alexandra, Larouche, Julie, Marquis, Tania, Nabid, Abdenour, Pearson, Diane, Sabbagh, Robert, TetreaultLaflamme, Audrey, Baker, Erin, Blackwood, Geoffrey, Galway, Denise, Greenland, Jonathan, Hannaford, Zeta, Hoskins, Ashley, House, Gail, Kamran, Asim, Manning, Kimberley, Nelder, Matthew, Noel, Lorilee, Norman, Alia, ODea, Jamie, Pinnell, Erin, Pochini, Craig, Putt, Dawne, Rahman, Arifur, Rickert, Lauren, Sathya, Jinka R, Teasdale, Breanne, Thoms, John, Whiteway, Chrystal, Whittle, Stacy, Cheung, Patrick CF, Chu, William, Chung, Hans T, Commisso, Angela, Danjoux, Cyril, Escueta, Vivette, Klotz, Laurence, Leung, Michael, Liu, Stanley, Loblaw, Douglas Andrew, Malek, Leila, Nam, Robert K, Szumacher, Ewa, Tseng, Eric Chia Lin, Vesprini, Danny, Abed, Jessy, Ang, Daniel, Bayley, Andrew J, Berlin, Alejandro, Bristow, Robert, Catton, Charles, Chan, Heidi, Chui, Amadeus, Chung, 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6. Duration of androgen deprivation therapy with postoperative radiotherapy for prostate cancer: a comparison of long-course versus short-course androgen deprivation therapy in the RADICALS-HD randomised trial
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Fatjon, Hillman, Paul, Jayachandran, Resmi, Kaliski, Alexandre, Kiff, Janet, Nicholson, Alastair, Nixon, Jude, Oladimeji, Janet, Riches, Oscar, Smith, Dan, Tipples, Karen, Wells, Paula, Anderson, Chris, Daly, Deirdre, Dover, Serena, Gilmartin, Claire, Golden, Sophie, Gregg, Jane, Issa, Rami, Oni, Titilayo, Patel, Chandni, Quarrell, Mark, Rolfe, Debbie, Tighe, Helen, Toledo, Jesusa, Tuazon, Juel, Varro, Robert, Bohra, Vikram, Caballes, Mark, Custins, Laura, Ivie, Stephanie, Joshi, Manisha, Liau, Joy, Naim, Farhan, Patel, Anup, Pathmanathan, Byiravey, Russell, Emily, Tippins, Anna, Agdiran, Didem, Aggarwal, Ajay, Amoaten, Thomas, Aslam, Natasha, Bonsu, Nicole, Butt, Zainab, Danaswamy, Patricia, Davda, Reena, Gillesen, Annelies, Goel, Roshni, Khong, Rachel, Lowi, Suzy, Merrick, Richard, Mitra, Anita, Payne, Heather, Teh, Jonathan, Whinn, Samantha, Woolf, David, Zilkha, Helene, Dawson-Athey, Linda, Foster, Emma, Gillian, Andrew, Green, James, Hines, John, Holden, Simon, Kazingizi, Memory, O'Neill, John, Olaoni, Thompson, Peters, John, Philp, Timothy, Zaidi, Sadaf, Adeyoju, Adebanji, Adinkra, Victoria, Brough, Richard, Brown, Stephen CW, Collins, Gerald, Hardstaff, Lisa, Hill, Pippa, Kujawa, Magda, McCurrie, Marilyn, Townley, Barbara, Woodhouse, Iain, Zafar, Waheed, Beesley, Sharon, Breen, Vivienne, Burrage, Su, Calvert, Clare, Davison, Alison, Dias, Heather, Fossey, Gavin, Hotine, Jodie, Jones, Ifan, Jope, Carmel, Lines, Yvonne, Martins, Sarah, Mercier, Barbara, Murray, Jane, Neshiri, Innocent, Pamphlett, Ian, Phillips, Ann, Rai, Pavnish, Roberts, Verity, Taylor, Henry, Tribe, Lisa, Bottomley, Ian, Buchan, Jonathan, Carpio, Viviana, Choudhury, Ananya, Conroy, Ruth, Cowan, Richard, Davison, Sue, Duncan, Ian, Elliott, Tony, Fair, Kim, Fallaize, Adrian, Flanagan, Laura, Green, Sarah, Harris, Catherine, Hart, Amber, Jones, Cathryn, Livsey, Jacqueline, McCaul, Damian, Nazari, Roonak, Newbery, Carol, O'Connor, Kate, O'Dwyer, Sister Jackie, Oliver, Joanne, Onoge, Ekugbe, Petsa, Maria, Redshaw, Catherine, Smith, Sarah-Ellen, Spoor, Willemijn, Thomas, Sister Viv, White, Holly, Worsley, Lucy, Bailey, Linda, Bennett, Molly, Corless, Rebecca, Duffy, Annie, Fellows, Kathryn, Gipson, Anna, Haydock, Helen, Knox, WF, Liptrott, Sarah, McCarth, Fiona, McCartin, Fiona, Mistry, Heena, Mthethwa, Thobekile, Partington, Lillian, Piper, Lindsay, Ramani, Vijay, Sahin, Sarah, Sangar, Vijay, Slevin, Kathryn, Tuck, Jonathan, Atkinson, Lorraine, Barnbrooke, Sarah, Barnes, Alison, Brownless, Caroline, Chadwick, David, Hardman, John, Harland, Keith, Long, Carol, McAuliffe, Sarah, McBride, Julia, McClurey, Sister Patricia, Mohan, Rita, Naylor, Lynne, Peedell, Clive, Robson, Paula, Shakespeare, Devadasan, Thompson, Emma, Van der Voet, Hans, Wilson, David, Barron, Chris, Frew, John, Lambert, Katy, McMenemin, Rhona, Pedley, Ian, Riseborough, Danielle, Roberts, Trevor, Stockley, Emma, Stoddart, Jonathan, Tate, Janine, Walker, Jayashree, Workman, Bridget, Barnett, Debra, Carter, Adam, Cox, Adam, Davey, Alison, Davies, Kirstin, Gilby, Lisa, Hodge, Simon, Kearney, S, Lavender, Helene, Marty, Janet, Nash, Maxine, Rahman, Syhed, Richards, Jayne, Simpson, Julie, Wall, Elaine, Webb, Paula, Wild, Karen, Wilson, Jim, Branagan, Jenny, Dell, Gillian, Foo, Maxine, Goyena, Ruby, Jones, Andrea, McBain, Hazel, McGrath, Katherine, O'Callaghan, Jane, Ramanathan, Dorai, Tee, Elizabeth, Thominson, Bronwen, Tighe (nee Bussey), Rachel, Beety, Jane, Birch, Richard, Bloomfield, Mark, Callam, Sara, Cooper, Adele, Darby, Helen, Healey, Gail, Heasley, Karen, Kapur, Guarav, London, Clare, Oosterom, Katrien, Ostrowski, Joe, Shobrook, Bridget, Turner, Sarah, Wade, Rob, Walker, Suzanne, Walton, Sharon, Websdale, Cheryl, White, Joanna, Alder, Leanne, Chivers, Rachael, Gooch, Carol, Howard, Lucy, Hutchinson, Camille, Jevons, Cody, Kumar, Daniel, Marley, Hazel, Mills, Jamie, Purves, Hanna, Sayers, Ian, Sundar, Santhanam, Szolin-Jones, Jacob, Walker, Georgina, Wood, Catherine, Cook, Wendy, Gill, Lisa, Johnson, Joanne, Johnstone, Dawn, Jones, Richard, Mistry, Leena, Scarratt, Lyndsay, Aiku, Abimbola, Ajzensztejn, Daniel, Al-Chamali, Hiba, Andrade, Gerard, Barber, Dave, Bekulart, Sylwia, Bhatnagar, Gagan, Boutflower, Jane, Brewster, Simon, Butterfield, Anne, Carroll, Weronika, Cole, David J, Coutts, Tim, Doyle, Kerrie, Durrant, Lisa, Green, Trish, Jampana, Raj, Jastrzebska, Patrycja, Kyffin, Phillippa, Langridge, Nicole, Lawrey, Sarah, Markus, Sarah, Marston, Kerrie, Mooney, Matthew, Mukkath, Sandra, Murphy, Ann, Owens, Rob, Ruane, Sarah, Sabbagh, Ahmad, Samkange, Grace, Sankighatta, Naveen, Skwarski, Michael, Stuart, Robert, Wellman, Sandie, Wilson, Jo, Cavanagh, Kerrie, Hollingdale, Abigail, Allen, Susan, Barter, Elisa, Gregory, Debbie, Ingle, Charlotte, Lawrence, Steph, Rooney, Paula-Joanne, Bishop, Emma, Brennan, Maria, Cogley, Lyn, Hammonds, John Christopher, McInerney, Paul, McLarty, Esther, Natale, Salvatore, Pascoe, Sarah, Purcell, Keith, Sells, Henry, Tyner, Sharah, yates, Victoria, Beamish, Neal, Blaney, Hilary, Clapp, Felicity, Clarke, Elizabeth, Coffin, Teresa, Davies, Joe, Downs, Nichola, Gillespie, Sally, Heckford, Louise, Iskender, Amanda, Orford, Sara, Pressdee, Sandy, Rix, Sophie, Wheelwright, Roger, Woodward, Elizabeth, Wright, Seonaid, Blight, Kathy, Dobson, Tracey, Hale, Jennifer, Harris-Burland, Angie, Khoury, Ghassan, Madhava, Kudingila, Meadows, Lorna, Nagar, Yoodhvir, Roca, Mila, Stacey, Wendy, Stephenson, Anna, Uherek, Maja, Virgo, Azarel, Watkinson, Catrin, Birtle, Alison, Chauhan, Zainab, Cornthwaite, Stephanie, Curtis, Sandra, Ellard, Rose, Fish, Nathan, Hefferon, Billy, Searle, Claire, Spickett, Helen, Walmsley, Catherine, Atkinson, Jane, Brown, Richard B, Cartwright, Debbie, Coomber, Kristy, Hunt, Allison, Kowalczyk-Williams, Wioletta, Lewis, Christina, Parr, Stephen, Purdon, Helen, Rogers, Paul, Vowell, Emma, Featherstone, Wendy, Hamilton, Joanna, Harrison, Alison, Hindle, Margaret, Hodson, Hayley, Isaew, Andrea, Knapp, Jeanette, Moss, Sarah, Gibbs, Stephanie, Gujral, Sandeep, Jannapureddy, Revanth, Kelkar, Anand, Martinou, Maria, Mills-Baldock, Tina, O'Brien, Neale, Subramaniam, Ramachandran, Tahir, Saad, Vandal, Mohammad Tanvir, Vu, Thi, Allen, Rachael, Betts, Chris, Bowmer, Amanda, Clarke, Noel, Cordwell, Amanda, Dharmaprasad, Soney, Duncan (nee Keatley), Claire, Farnworth, Christine, Farrell, Helen, George, Siny, Goulden, Kay, Harter, Leah, Kaushal, Malan, Kirk, Sister Sarah, Lau, Maurice, Lydon, Anne Marie, O'Flynn, Kieran, Platt, Danielle, Shackley, David, Stevenson, Garry, Taylor, Sister Melanie, Thompson, Chloe-Anne, Vinod, Cellins, Wadsworth, Oliver, Youd, Sister Jill, Attlee, Julie, Bhatnagar, Adityanarayan, Bunn, Sarah, Campbell, Allister, El-Saghir, Mohammed, Fennelly, Ruth, Guy, Peter, Mattocks, Lehentha, Mcintosh, Gregor, Murphy, Brenda, Reed, Catherine, Strong-Sheldrake, Sophia, Tedd, Gemma, Dent, Kathleen, Hood, Marion, Martin, Karen, Pearson, Sandra, Potoczna, Dorota, Spencer, Sue, Towse, Jo, Whotton, Nikita, Bowen, Katie, Clark, Su, Clarke, Rachael, Gibbins, Kate, Martin, Jackie, Smith, Suzanne, Spalton, Catherine, Tay, Jessica, Adams, Marion, Bates, Emma, Chennattukungu, Indukala, Clancy, Joanna, Cross, Vanessa, Hughes, Hayley, Jose, Sanal, Kurian-Downer, Sunita, Michael, Elena, Moore, Sister Helen, Nicholas, Karen, Pope, Suzanne, Potts, Sally, Prashant, Ravi, Singh, Harpreet, Smith, Sandra, Srihari, Narayanan, Weaver, Emma, Abbas, Ali, Barnes, Nicky, Dallas, Nicola, Jackson, Sister Ann, Kader, Nicole, Karim, Omer, Laniado, M, Litchfield, Jayne, Mahmood, Sana, O'Donnell, Helen, Robinson, Victoria, Sears, Alison, Sharif, Shahid, Sierra Pala, Ana, Sinclair, Julie-Ann, Smith, Sister Catherine, Ashcroft, Jan, Boardman, John, Bowes-Cavanagh, Jeanette, Brown, Rebecca, Chedham, Alison, Darch, Flora, Farrar, Michelle, Foot, Jayne, Goldsworthy, Simon, Graham, John, Gray, Emma, Green, Sara, Jelski, Joseph, Kalejaiye, Odunayo, Keni, Manjusha, Locke, Angela, Mahoney, Sue, McMeekin, Faith, Periasamy, Manivannan, Russell, Tamlyn, Ruszala, Elizabeth, Segaran, Surayne, Tighe, Mary, Wallbutton, Rebecca, Webster, Christine, Whitcher, Alison, Wiggins, Sarah, Wrigley, Martha, Zietz, Maria, Abab, Julie, Cumming, Kirsty, Galloway, Lucy, Ganabady, Malavika, Haskell, Annelise, Heath, Catherine, James, Naomi, Kennedy, Julie, McFarlane, Victoria, Morales-Azofra, Fabiola, Morton, Susan, Mundy, Carina, Noble, Mark, Paschalis, Alec, Patrick, Julie, Reader, Leanne, Taylor, Lisa, Wakefield, Shauna, Ahmed, Imtiaz, Bowman, Sue, Chan, Olivia, Cyriac, Abby, Davies, Tracey, Maitland, Katrina, Prejbisz, Jan, Reece, Sheila, Shires, Heather, Tsang, David, Anscombe, Eleanor, Brough, WA, Clitheroe, Pat, Cocks, Tracie, Connolly nee McKenna, Sarah, Corcoran, Sam, Coughlan, Tricia, Gilmour, Christina, Goodwin, Emma, Graham, Susan, Hatimy, Umi, Hodgkinson, Sheila, Kilmartin, John, Orrell, Lucy, Rotherham, Carol, Smallwood, Sarah, Taylor, Jill, Wiss, Elliott, Adab, Fawzi, Bhana, 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Marchant), Emily, Johnstone, Maria, Jones, Lewis, Lemon, Nicola, Phan, Mau-Don, Pudney, Delia, Spence, Rachael, Stretch, Alison, Tait, Ellen, Williams, Bethan, Belcher, Rebecca, De Silva-Minor, Shiroma, Dodge, Sister Jan, Grayland, Sarah, Jones, Ania, Khan, Omar, Owen, Tim, Palmer, Debbie, Parajes, Cerila, Pegler, Suzannah, Poole, Abbie, Sargent, Sister Tracey, Starling, Ellen, Taylor, Becky, Winter, Sister Helen, Zinyemba, Vivian, Allison, Michele, Blundell, Martyn, Brookman, Catherine, Buckley, Jon, Chamberlain, Shelley, Cuffe, Donna, Davies, Stacey, Fairfax, Claire, Greedus, Helen, Griffin, Hannah, Koehler, Ingrid, Lydon, Anna, Michels, Jorg, Pym, Julia, Roberts, Fiona, Thornton, Lorraine, Vandecandalaere, Elaine, Watts, Erica, Welsh, Linda, Anderson, Jim, Anderson, Juliette, Ball, Julie, Benton, Louise, Bowers, Richard, Chahal, Rohit, Dickinson, Peter, Fosker, Chris, Heeley, Janine, Kanaga-Sundaram, Subramanian, Littler, Stephen, Slack, Jonathan, Sundaram, Subramanian Kanaga, Taylor, Beverley, Weston, Philip, Chettle, Judith, Hartwell, Lyn, Johnson-Rollings, Ashley, Jones, Julia, Millage, Helen, O'Neill, Eilish, Walsh, Donna, Webb, Kerrie, Williams, Jo, Dymond, Harvey, Eleftheriadis, Symeon, Lloyd-Jones, Hugh, Wells, Tom, Bennett, Sarah, Dunn, Sharon, Fildes, Diane, Hassall, Alison, Herbert, Gaynor, Hughes, Kathryn, Innes, Helen, Kelly, Alison, Littler, John, Lomax, Laurie, Miller, Nikki, Nutman, Chris, Stott, Matthew, Syndikus, Isabel, Tolan, Shaun, Weston, Alison, Baker, Ivanna, Carter, Vanda, Chatfield, Jenny, Cooke, Peter, Grant, Anna, Homer, David, Kirk, Christine, Lomas, Claire, McCormick, Marian, Mohseeni, Arizoo, Pawaroo, Renita, Radford, Liz, Rogers, Jason, Samanci, Ali, Sharman, Emma, Spencer, Hazel, Spruce, Debbie, Worthington, Hannah, Bak, Dagmara, Cleary, Kristy, Davies, Sue, Gauntlett, Monica, Gupta, Kamalnayan, Holdsworth, Amanda, Ledger, Kate, Morrow, Hugh, Perry, Heather, Rimell, Patricia, Rosoman, Alison, Tyler, Jayne, White, Ann, Crowe (nee Hughes), Dawn, Flynn-Batham, Marian, Folkes, Linda, Funnell, Sarah, Gilbert, Jeanette, Gomez-Marcos, Raquel, Gonzalez, Celia, Hoskins, Chloe, Moore, Sally, Plataniotis, George, Rippin, Sarah, Smith, Matthew, Tsawayo, Tan, Turner, Nikki, Wakelen, Paula, Cserbane, Anita, Fernandez, Claire, Kurup, Rahul, Manyangadze, Sarah, McLain-Smith, Susan, Protheroe, Andrew, Trewsmith, Neil, Allison, Joanna, Barron, Claire, Beaumont, Erica, Beer, Nigel, Beesley, Kate, Donaldson, David, Duckett, Tracey, Fox, Shirley, Kotze, Michelle, Kumar, Shiyam, Macrory, Joanne, Perry, Jess, Pippard, Lucy, Porter, Tim, Rennie, Kerry, Sparrow, Geoffrey, Williams-Yesson, Barbara, Balderson, Jane, Bowling, Lorna, Brittain, Paul, Brookes, Claire, Campbell, Hilary, Campos, Monica, Conway, Rachel, Davies, Flor, Donnison, Michelle, Elliott, Mark, Evans, Richard, Fallah, Fereshteh, Fearnley, Mark, Giddings, Emma, Gollapothu, Srilakshmi, Harvey, Sally, Holbrook, Andy, Ingham, Jo, Jakeman, Christine, Joseph, Joji, Mole, Lisa, Musunuru, Hima Bindu, Pashley, Sarah, Saleem, Shamila, Stower, Michael, Strider, Paula, Taylor, Carol, Thackray, Louis, Todd, Joanna, Wightman, John, Wilson, Russ, Youngs, Nora, Byrne, Mary Marg, Deenihan, Emma, Durkan, Garret, Jennings, Marian, Mahoney, Catriona, Martin, Joseph, McInerney, Veronica, Raftery, Liz, Rogers, Eamonn, Spillane, Maria, Sullivan, Frank, Teh, Chiaw Woon, Wright, Ann, Harving, Niels, Hejlesen, Finn, Kempel, Mette Moe, Steffensen, Kirsten, Bentzen, Lise, Borre, Michael, Buus, Simon, Fode, Kirsten, Kaa Bach, Birgit, Lassen, Yasmin, Laursen, Vibeke, Lemng Kruse, Helle, Lucakova, Slavka, Nørmark Iversen, Helle, Brasso, Klaus, Christensen, Anne Juel, Gruschy, Lisa, Klovgaard, Karina, Lunau, Anne Sofie, Meidhal Petersen, Peter, Moller Christensen, Trine, Poder, Lone Lund, Ribers, Kristine, Stilling, Sine, Thim, Stine, Torin Lehmann, Anna, Vandborg, Maria, Christensen, Tine, Kokholm, Kathrine Friser, Lindberg, Henriette, Nybom, Kirstine, Rønnengart, Eva, Saxe, Charlotte, Baird, Noelle, Braun, Michael W, Cheung, Arthur, Fourt, Monica, Jackson, Cathy, Jepson, Debbie, Johnson, Arlissa, Karvat, Anand, Kwan, Winkle, McIndoe, Sue, Mitchell, Donna, Sandhu, Sandeep, Serpanchy, Rosanne, Wu, Helen, Beausoleil, Rachelle, Crawford, Melanie, DiMarco, Christine, Ding, Ian, Gladwish, Adam, MacIsaac, Patricia, MarshGray, Kimberley, Morton, Gerard, Murphy, Cara, Pascoe, Caitlin, Pokhrel, Sujata, Stevens, Christiaan, Yoon, Frederick, Yu, Jason, Dubey, Arbind, Sivananthan, Gokulan, Bahary, JeanPaul, Barkati, Maroie, Beauchemin, MarieClaude, Benth, Silvine, Carbonaro, Adriana, Delouya, Guila, ElSokhn, Nidale, Frazzi, Alexandra, Lambert, Carole, Lavertu, Sophie, Menard, Cynthia, Pan, Siew Siew, Rousseau, Pierre, Saad, Fred, Taussky, Daniel, Trudel, Diane, Amanie, John Oliver, Batz, Margaret, Borynec, Carol, Danielson, Brita, Garcia, Leni Santiago, Gramlich, Colin, Lang, Monika, Larson, Beverly, Mallett, Debbie, McCrudden, Sylvia, Murtha, Albert, Parker, Shelley, Parliament, Matthew B, Patel, Samir, Pearcey, Robert, Pervez, Nadeem, Rose, Jim, Shewchuk, Caroline, Smith, Carlie, Usmani, Nawaid, Williams, Candra, Yee, Don, AlRashdan, Abdulla, Avery, Alison, Beaton, Heather, Bond, Brittany, BrucePayne, Kim, Burbridge, Susan, Bursey, Kara, Carvery, Lane, Dill, Kendra, Dugas, Stevie, Harding, Claudia, Hodder, June, Hollenhorst, Helmut, Hubley, Lynn, Joseph, Paul K, Little, Erin, MacDonald, Angela, MacIsaac, Kathy, MacVicar, Jennifer, McCracken, Jillian, Moffatt, Emily, Nieforth, Joan, Patil, Nikhilesh, Rijt, Kelsey van der, Roberts, Victoria, Rose, Tina, Rutledge, Robert DH, Salyzyn, Camryn, Simpson, Robin, Sutherland, Donna, Walker, Heather, Wilke, Derek, Yeo, Tanya, Yunace, Lorrie, Zinck, Connie, Bier, Bianca, Bucci, Catherine, Corbett, Thomas B, Dayes, Ian S, Eady, Robin, Gudelis, Susan O, Hill, Elaine, Kinrade, Yvonne, Laughlin, Anne, Lukka, Himu, Makepeace, Barbara, Marshall, Lynn, Nielsen, Linda, Oliverio, Carmela, Patel, Malti Behn, Tsakirdis, Thedoros, Wong, Jason W T, Allen, Kirsten, Bachand, Francois, Carefoot, Layton, Cotts, Shannon, Creelman, Brianna, Crook, Juanita, GeorgeChayka, Danielle, Halperin, Ross, Hartt, Nancy, Hayes, Jill A, Kim, David, Kim, TuongVan, Kronstal, Flo, Lee, Bernard, Lew, Tanya, McClelland, Marie, Opitz, Debbie, Overend, Aldyn, Reed, Melanie, Watson, Michaella, Wilkie, Karen, Winn, Carol, Yanchuk, Janet, Bonner, Scott, Brander, Mike, Brundage, Michael, Carlson, Cindy, Edwards, Jackie, ElKerdawy, Hala, Harpell, Rhonda, Hartman, Carrie, Kalyvas, Maria, KirbyBello, Denise, Kumar, Vikaash, Leach, Deborah, MacVicar, Karen, Mahmud, Aamer, Maize, Christine, Moelker, Yvonne, Murano, Abby, Paul, Nancy, Ross, Ashley, RossSmith, Marleen, Shenfield, Carey, Spencer, Craig, Tennant, Virginia, Vermette, Tracy, Willing, Stephanie, Zaza, Khaled O, Zeltser, Fred, Gearing, Jennifer, Girolametto, Carla, Gopaul, Darindra, Hamilton, Ronald, Hendel, Debra, Janke, Susan, Knackstedt, Jochen, Kuk, Joda, Morrison, MaryBeth, 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Souhami, Luis, Albrecht, Virginia, Froese, Jane, Froude, Nancy, Howitt, Pamela, Iqbal, Fawaad, Kift, Shannon, Koll, Wayne, Li, Audrey, MacGregor, Barbara, Manganaro, Aileen, McKee, Dianne, Mendoza, Edeliza, Mui, Jimmy, Myrehaug, Sten, Singson, Angelina, Slessor, Janet, Somasiri, Ashane, Stevens, Nicole, Berghout, Koralee, Bourque, JeanMarc, Carkner, Amy, E, Choan, Eapen, Libni, Eze, Nancy, Fish, Matt, Haddad, Alain, Hicks, Kimberly, Iordanidi, Elina, Kanji, Femina, Kendal, Wayne S, MacMullin, Lisa, MacRae, Robert M, Malone, Shawn, Morgan, Scott, Nguyen, Julie, OBrien, Anna, Page, Nancy, Perry, Gad A, Reeves, MarieClaude, Roach, Joanne, Sanchez, Maria, Spearman, Mary, Spencer, Patti, Tikoo, Archana, Turriff, Lisa, Wright, Natalie, Bedoya, Luis Diaz de, Cossette, Danielle, Cusan, Leonello, Desrosiers, Isabelle, Dufour, Nathalie, Foster, William, Gomez, JoseLuis, Hathout, Lara, Lajoie, MarieAndree, Martin, AndreGuy, Pouliot, Sophie, Vigneault, Eric, Bouchard, Myriam, Bujold, Rachel, Carmel, Michel, Cote, Genevieve, Dion, Helene, Ebacher, Annie, Gauthier, Isabelle C, Ladouceur, Cynthia, Lamoureux, Alexandra, Larouche, Julie, Marquis, Tania, Nabid, Abdenour, Pearson, Diane, Sabbagh, Robert, TetreaultLaflamme, Audrey, Baker, Erin, Blackwood, Geoffrey, Galway, Denise, Greenland, Jonathan, Hannaford, Zeta, Hoskins, Ashley, House, Gail, Kamran, Asim, Manning, Kimberley, Nelder, Matthew, Noel, Lorilee, Norman, Alia, ODea, Jamie, Pinnell, Erin, Pochini, Craig, Putt, Dawne, Rahman, Arifur, Rickert, Lauren, Sathya, Jinka R, Teasdale, Breanne, Thoms, John, Whiteway, Chrystal, Whittle, Stacy, Cheung, Patrick CF, Chu, William, Chung, Hans T, Commisso, Angela, Danjoux, Cyril, Escueta, Vivette, Klotz, Laurence, Leung, Michael, Liu, Stanley, Loblaw, Douglas Andrew, Malek, Leila, Nam, Robert K, Szumacher, Ewa, Tseng, Eric Chia Lin, Vesprini, Danny, Abed, Jessy, Ang, Daniel, Bayley, Andrew J, Berlin, Alejandro, Bristow, Robert, Catton, Charles, Chan, Heidi, Chui, Amadeus, Chung, Peter, Degendorfer, Sarah, Gospodarowicz, Mary, Gregorcic, Emily, Gumapac, Nicole, Helou, Joelle, Hsien, John, Kong, Vickie, Lalani, Nafisha, Lao, Bernadeth, Lawson, Daeria, Merante, Pat, Milosevic, Michael, Mirmooji, Ramesh, Muraj, Zaynab, Peres, Sarin, Petroff, Avi, Petrovska, Aleksandra, Pineda, Sandra, Quintos, Judy, Raman, Srinivas, Ramotar, Sarah, Ruiz, Maria Jose Gaitan, Sabate, Kathryn, Shukla, Arundhati, Tharahan, Nanthini, Thevarajah, Vaishaali, Tiessen, Kyoko, Topalovich, Aleksandra, Torres, Cynthia, Tse, Karen, Tsuji, Debbie, Velec, Erin, Wallace, Kris, Warde, Padraig, Bisson, MarieEve, Dahmane, Rafika, Gagne, Vanessa, Harvey, Julie, Lebrun, Benoit, Marineau, Line, Montour, Julie, Samson, Julie, Sicard, MarieEve, Thibeault, Andreanne, Vincent, Francois, Vincent, LindaSuzanne, Blood, Paul A, Canavan, Joycelin, Clements, Mia AnnaMaria, Glick, Daniel, Holloway, Caroline, Holwerda, Eleanor, Joe, Howard, Lacey, Cathy, Lam, Jacqueline, Leong, Nelson, Lim, Jan, Lomas, Alia, Pai, Howard H, Priestley, Emilie, Shahid, Negin, Vallieres, Isabelle, Duncan, Graeme, Gleave, Martin E, Goldenberg, S Larry, Karunakaran, Subashini, Keyes, Mira, KimSing, Charmaine, McKenzie, Michael, Morris, William James, Nakashima, Lynne, Peacock, Michael, Pickles, Thomas A, Sibug, Sheena, So, Alan I, Tyldesley, Scott, Zhang, Tina Wanting, Ahmed, Shahida, Ammeter, Barb, Anderson, Leanne, Ann, Taehee, Bakija, Zeljka, Bashir, Bashir, Benjaminson, Patricia, Bergen, Leah, Cadiz, Lovely, Chahine, Jacqueline, Cherepak, Kathy, Chornopyski, Tracy, Chowdhury, Amitava D, Davies, Heather, Dawe, David, Drachenberg, Darrel E, DuMontier, Joelle, Eska, Tiffani, Francisco, Cristina, Gamez, Raquel, Garrett, Gina, Giovannini, Julia, Graham, Jeffrey, Guarino, Robyn, Hunter, William, Johnston, Laurel, Kitkowski, Caitlin, Klapp, Kathi, Koul, Rashmi, Kuzyk, Valerie, Last, Debbie, Li, KuanLin, Long, Heather, Majumdar, Arpita, Marek, Kathleen, McNish, Jennifer, Mills, Laurie, Morales, Maria, Nashed, Maged, Nichol, Rhonda, Ong, Aldrich Dixon, Ouelette, Ashley, Patel, DeepKumar, Pawl, Marilyn, Peak, Lisa, Priebe, Shauna, Quon, Harvey, Rizzuto, Stacey, Rudnicki, Rayleen, Santos, Priscilla, Sharma, Atul, Squires, Mandy, Trakalo, Kathy, Turner, Christy, Vaughn, Jamie, Walker, Lori, Watson, Melanie R, Wei, Joyce, Weir, JoAnn, Woloshyn, Rose, Wood, Allison, Zhang, Hanbo, Zwarych, Darlene, Parker, Chris C, Cook, Adrian D, Clarke, Noel W, Catton, Charles N, Cross, William R, Petersen, Peter M, Persad, Rajendra A, Pugh, Cheryl A, Bower, Lorna C, Bottomley, David M, Chung, Peter W M, Ford, Vicky, Goh, Chee L, Heath, Catherine M, James, Nicholas D, Kim-Sing, Charmaine, Kodavatiganti, Ravi, Malone, Shawn C, Morris, Stephen L, Ong, Aldrich D, Parulekar, Wendy R, Parmar, Mahesh K B, and Sydes, Matthew R
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7. A population-scale temporal case–control evaluation of COVID-19 disease phenotype and related outcome rates in patients with cancer in England (UKCCP)
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Starkey, Thomas, Ionescu, Maria C., Tilby, Michael, Little, Martin, Burke, Emma, Fittall, Matthew W., Khan, Sam, Liu, Justin K. H., Platt, James R., Mew, Rosie, Tripathy, Arvind R., Watts, Isabella, Williams, Sophie Therese, Appanna, Nathan, Al-Hajji, Youssra, Barnard, Matthew, Benny, Liza, Burnett, Alexander, Bytyci, Jola, Cattell, Emma L., Cheng, Vinton, Clark, James J., Eastlake, Leonie, Gerrand, Kate, Ghafoor, Qamar, Grumett, Simon, Harper-Wynne, Catherine, Kahn, Rachel, Lee, Alvin J. X., Lomas, Oliver, Lydon, Anna, Mckenzie, Hayley, Panneerselvam, Hari, Pascoe, Jennifer S., Patel, Grisma, Patel, Vijay, Potter, Vanessa A., Randle, Amelia, Rigg, Anne S., Robinson, Tim M., Roylance, Rebecca, Roques, Tom W., Rozmanowski, Stefan, Roux, René L., Shah, Ketan, Sheehan, Remarez, Sintler, Martin, Swarup, Sanskriti, Taylor, Harriet, Tillett, Tania, Tuthill, Mark, Williams, Sarah, Ying, Yuxin, Beggs, Andrew, Iveson, Tim, Lee, Siow Ming, Middleton, Gary, Middleton, Mark, Protheroe, Andrew, Fowler, Tom, Johnson, Peter, and Lee, Lennard Y. W.
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- 2023
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8. Germline and Somatic Genetic Variants in the p53 Pathway Interact to Affect Cancer Risk, Progression, and Drug Responsep53 Pathway SNPs and Mutations Interact to Affect Cancer
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Zhang, Ping, Kitchen-Smith, Isaac, Xiong, Lingyun, Stracquadanio, Giovanni, Brown, Katherine, Richter, Philipp H, Wallace, Marsha D, Bond, Elisabeth, Sahgal, Natasha, Moore, Samantha, Nornes, Svanhild, De Val, Sarah, Surakhy, Mirvat, Sims, David, Wang, Xuting, Bell, Douglas A, Zeron-Medina, Jorge, Jiang, Yanyan, Ryan, Anderson J, Selfe, Joanna L, Shipley, Janet, Kar, Siddhartha, Pharoah, Paul D, Loveday, Chey, Jansen, Rick, Grochola, Lukasz F, Palles, Claire, Protheroe, Andrew, Millar, Val, Ebner, Daniel V, Pagadala, Meghana, Blagden, Sarah P, Maughan, Timothy S, Domingo, Enric, Tomlinson, Ian, Turnbull, Clare, Carter, Hannah, and Bond, Gareth L
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Clinical Research ,Cancer ,Prevention ,Human Genome ,Patient Safety ,Genetics ,Biotechnology ,Digestive Diseases ,2.1 Biological and endogenous factors ,Aetiology ,Animals ,Antineoplastic Agents ,Biomarkers ,Pharmacological ,Carcinogenesis ,Case-Control Studies ,Cell Line ,Tumor ,Disease Progression ,Drug Resistance ,Neoplasm ,Female ,Genetic Predisposition to Disease ,Genome-Wide Association Study ,Germ-Line Mutation ,Humans ,Male ,Mice ,Mice ,Inbred BALB C ,Mice ,Nude ,Mutation ,Missense ,Neoplasms ,Polymorphism ,Single Nucleotide ,Prognosis ,Risk Factors ,Signal Transduction ,Treatment Outcome ,Tumor Suppressor Protein p53 ,Oncology and Carcinogenesis ,Oncology & Carcinogenesis - Abstract
Insights into oncogenesis derived from cancer susceptibility loci (SNP) hold the potential to facilitate better cancer management and treatment through precision oncology. However, therapeutic insights have thus far been limited by our current lack of understanding regarding both interactions of these loci with somatic cancer driver mutations and their influence on tumorigenesis. For example, although both germline and somatic genetic variation to the p53 tumor suppressor pathway are known to promote tumorigenesis, little is known about the extent to which such variants cooperate to alter pathway activity. Here we hypothesize that cancer risk-associated germline variants interact with somatic TP53 mutational status to modify cancer risk, progression, and response to therapy. Focusing on a cancer risk SNP (rs78378222) with a well-documented ability to directly influence p53 activity as well as integration of germline datasets relating to cancer susceptibility with tumor data capturing somatically-acquired genetic variation provided supportive evidence for this hypothesis. Integration of germline and somatic genetic data enabled identification of a novel entry point for therapeutic manipulation of p53 activities. A cluster of cancer risk SNPs resulted in increased expression of prosurvival p53 target gene KITLG and attenuation of p53-mediated responses to genotoxic therapies, which were reversed by pharmacologic inhibition of the prosurvival c-KIT signal. Together, our results offer evidence of how cancer susceptibility SNPs can interact with cancer driver genes to affect cancer progression and identify novel combinatorial therapies. SIGNIFICANCE: These results offer evidence of how cancer susceptibility SNPs can interact with cancer driver genes to affect cancer progression and present novel therapeutic targets.
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- 2021
9. Publisher Correction: Clinical efficacy and biomarker analysis of neoadjuvant atezolizumab in operable urothelial carcinoma in the ABACUS trial
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Powles, Thomas, Kockx, Mark, Rodriguez-Vida, Alejo, Duran, Ignacio, Crabb, Simon J., Van Der Heijden, Michiel S., Szabados, Bernadett, Pous, Albert Font, Gravis, Gwenaelle, Herranz, Urbano Anido, Protheroe, Andrew, Ravaud, Alain, Maillet, Denis, Mendez, Maria Jose, Suarez, Cristina, Linch, Mark, Prendergast, Aaron, van Dam, Pieter-Jan, Stanoeva, Diana, Daelemans, Sofie, Mariathasan, Sanjeev, Tea, Joy S., Mousa, Kelly, Banchereau, Romain, and Castellano, Daniel
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- 2023
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10. Abiraterone acetate plus prednisolone with or without enzalutamide for patients with metastatic prostate cancer starting androgen deprivation therapy: final results from two randomised phase 3 trials of the STAMPEDE platform protocol
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Jones, Elin, Hyde, Katherine, Glen, Hilary, Needleman, Sarah, McGovern, Ursula, Sheehan, Denise, Paisey, Sangeeta, Shaffer, Richard, Beresford, Mark, Malik, Zafar, Zarkar, Anjali, Porfiri, Emilio, Fackrell, David, Lee, Ling, Sreenivasan, Thiagarajan, Brock, Sue, Brown, Simon, Bahl, Amit, Smith-Howell, Mike, Woodward, Cathryn, Phan, Mau-Don, Mazhar, Danish, Narahari, Krishna, Tanguay, Jacob, Douglas, Fiona, Kumar, Anil, Hamid, Abdel, Ibrahim, Azman, Muthukumar, Dakshinamoorthy, Simms, Matthew, Worlding, Jane, Tran, Anna, Kagzi, Mohammed, Das, Prantik, Pezaro, Carmel, Sivoglo, Virgil, Masters, Benjamin, Keng-Koh, Pek, Manetta, Caroline, McLaren, Duncan, Gupta, Nishi, Boussios, Stergios, Taylor, Henry, Graham, John, Perna, Carla, Melcher, Lucinda, Grant, Warren, Sabharwal, Ami, Hofmann, Uschi, Dealey, Robert, McPhail, Neil, Brierly, Robert, Capaldi, Lisa, Sidek, Norma, Whelan, Peter, Robson, Peter, Falconer, Alison, Rudman, Sarah, Vivekanandan, Sindu, Mullessey, Vinod, Vilarino-Varela, Maria, Khoo, Vincent, Tipples, Karen, Afshar, Mehran, Brulinski, Patryk, Sangar, Vijay, Peedell, Clive, Azzabi, Ashraf, Hoskin, Peter, Mullassery, Viwod, Sundar, Santhanam, Khan, Yakhub, Conroy, Ruth, Protheroe, Andrew, Carser, Judith, Rogers, Paul, Tarver, Kathryn, Gibbs, Stephanie, Khan, Mohammad Muneeb, Hingorani, Mohan, Crabb, Simon, Alameddine, Manal, Bhalla, Neeraj, Hughes, Robert, Logue, John, Leaning, Darren, Vengalil, Salil, Ford, Daniel, Walker, Georgina, Shaheen, Ahmed, Khan, Omar, Chan, Andrew, Ahmed, Imtiaz, Hilman, Serena, Sayers, Ian, Nikapota, Ashok, Bloomfield, David, Porter, Tim, Joseph, Joji, Rentsch, Cyrill, Pereira Mestre, Ricardo, Roggero, Enrico, Beyer, Jörg, Borner, Markus, Strebel, Raeto, Berthold, Dominik, Engeler, Daniel, John, Hubert, Popescu, Razvan, Durr, Donat, Attard, Gerhardt, Murphy, Laura, Clarke, Noel W, Sachdeva, Ashwin, Jones, Craig, Hoyle, Alex, Cross, William, Jones, Robert J, Parker, Christopher C, Gillessen, Silke, Cook, Adrian, Brawley, Chris, Gilson, Clare, Rush, Hannah, Abdel-Aty, Hoda, Amos, Claire L, Murphy, Claire, Chowdhury, Simon, Russell, J Martin, Parkar, Nazia, Pugh, Cheryl, Diaz-Montana, Carlos, Saxby, Helen, Pedley, Ian, O'Sullivan, Joe M, Birtle, Alison, Gale, Joanna, Srihari, Narayanan, Thomas, Carys, Wagstaff, John, Gray, Emma, Alzouebi, Mymoona, Parikh, Omi, Robinson, Angus, Montazeri, Amir H, Wylie, James, Cathomas, Richard, Brown, Michael D, Jain, Yatin, Dearnaley, David P, Mason, Malcolm D, Gilbert, Duncan, Langley, Ruth E, Millman, Robin, Matheson, David, Sydes, Matthew R, Brown, Louise C, Parmar, Mahesh K B, and James, Nicholas D
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- 2023
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11. Biomarkers associated with survival in patients with platinum-refractory urothelial carcinoma treated with paclitaxel
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Jackson-Spence, Francesca, Ackerman, Charlotte, Jones, Robert, Toms, Charlotte, Jovaisaite, Agne, Young, Matthew, Hussain, Syed, Protheroe, Andrew, Birtle, Alison, Chakraborti, Prabir, Huddart, Robert, Jagdev, Santinder, Bahl, Amit, Sundar, Santhanam, Crabb, Simon, Powles, Thomas, and Szabados, Bernadett
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- 2024
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12. Final Results of Neoadjuvant Atezolizumab in Cisplatin-ineligible Patients with Muscle-invasive Urothelial Cancer of the Bladder
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Szabados, Bernadett, Kockx, Mark, Assaf, Zoe June, van Dam, Pieter-Jan, Rodriguez-Vida, Alejo, Duran, Ignacio, Crabb, Simon J., Van Der Heijden, Michiel S., Pous, Albert Font, Gravis, Gwenaelle, Herranz, Urbano Anido, Protheroe, Andrew, Ravaud, Alain, Maillet, Denis, Mendez, Maria Jose, Suarez, Cristina, Linch, Mark, Prendergast, Aaron, Tyson, Charlotte, Stanoeva, Diana, Daelemans, Sofie, Rombouts, Miche, Mariathasan, Sanjeev, Tea, Joy S., Mousa, Kelly, Sharma, Shruti, Aleshin, Alexey, Banchereau, Romain, Castellano, Daniel, and Powles, Thomas
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- 2022
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13. Vaccine effectiveness against COVID-19 breakthrough infections in patients with cancer (UKCCEP): a population-based test-negative case-control study
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Kinloch, Emma, Lam, Emily, Murphy, Gillian, Rhodes, Malcolm, Robinson, Kate, Lee, Lennard Y W, Starkey, Thomas, Ionescu, Maria C, Little, Martin, Tilby, Michael, Tripathy, Arvind R, Mckenzie, Hayley S, Al-Hajji, Youssra, Barnard, Matthew, Benny, Liza, Burnett, Alexander, Cattell, Emma L, Charman, Jackie, Clark, James J, Khan, Sam, Ghafoor, Qamar, Illsley, George, Harper-Wynne, Catherine, Hattersley, Rosie J, Lee, Alvin J X, Leonard, Pauline C, Liu, Justin K H, Pang, Matthew, Pascoe, Jennifer S, Platt, James R, Potter, Vanessa A, Randle, Amelia, Rigg, Anne S, Robinson, Tim M, Roques, Tom W, Roux, René L, Rozmanowski, Stefan, Tuthill, Mark H, Watts, Isabella, Williams, Sarah, Iveson, Tim, Lee, Siow Ming, Middleton, Gary, Middleton, Mark, Protheroe, Andrew, Fittall, Matthew W, Fowler, Tom, and Johnson, Peter
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- 2022
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14. Abiraterone acetate and prednisolone with or without enzalutamide for high-risk non-metastatic prostate cancer: a meta-analysis of primary results from two randomised controlled phase 3 trials of the STAMPEDE platform protocol
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Jones, Elin, Hyde, Katherine, Glen, Hilary, Needleman, Sarah, McGovern, Ursula, Sheehan, Denise, Paisey, Sangeeta, Shaffer, Richard, Beresford, Mark, Malik, Zafar, Zarkar, Anjali, Porfiri, Emilio, Fackrell, David, Lee, Ling, Sreenivasan, Thiagarajan, Brock, Sue, Brown, Simon, Bahl, Amit, Smith-Howell, Mike, Woodward, Cathryn, Phan, Mau-Don, Mazhar, Danish, Narahari, Krishna, Tanguay, Jacob, Douglas, Fiona, Kumar, Anil, Hamid, Abdel, Ibrahim, Azman, Muthukumar, Dakshinamoorthy, Simms, Matthew, Worlding, Jane, Tran, Anna, Kagzi, Mohammed, Das, Prantik, Pezaro, Carmel, Sivoglo, Virgil, Masters, Benjamin, Keng-Koh, Pek, Manetta, Caroline, McLaren, Duncan, Gupta, Nishi, Boussios, Stergios, Taylor, Henry, Graham, John, Perna, Carla, Melcher, Lucinda, Grant, Warren, Sabharwal, Ami, Hofmann, Uschi, Dealey, Robert, McPhail, Neil, Brierly, Robert, Capaldi, Lisa, Sidek, Norma, Whelan, Peter, Robson, Peter, Falconer, Alison, Rudman, Sarah, Vivekanandan, Sindu, Mullessey, Vinod, Vilarino-Varela, Maria, Khoo, Vincent, Tipples, Karen, Afshar, Mehran, Brulinski, Patryk, Sangar, Vijay, Peedell, Clive, Azzabi, Ashraf, Hoskin, Peter, Mullassery, Viwod, Sundar, Santhanam, Khan, Yakhub, Conroy, Ruth, Protheroe, Andrew, Carser, Judith, Rogers, Paul, Tarver, Kathryn, Gibbs, Stephanie, Khan, Mohammad Muneeb, Hingorani, Mohan, Crabb, Simon, Alameddine, Manal, Bhalla, Neeraj, Hughes, Robert, Logue, John, Leaning, Darren, Vengalil, Salil, Ford, Daniel, Walker, Georgina, Shaheen, Ahmed, Khan, Omar, Chan, Andrew, Ahmed, Imtiaz, Hilman, Serena, Sayers, Ian, Nikapota, Ashok, Bloomfield, David, Porter, Tim, Joseph, Joji, Rentsch, Cyrill, Pereira Mestre, Ricardo, Roggero, Enrico, Beyer, Jörg, Borner, Markus, Strebel, Raeto, Berthold, Dominik, Engeler, Daniel, John, Hubert, Popescu, Razvan, Durr, Donat, Attard, Gerhardt, Murphy, Laura, Clarke, Noel W, Cross, William, Jones, Robert J, Parker, Christopher C, Gillessen, Silke, Cook, Adrian, Brawley, Chris, Amos, Claire L, Atako, Nafisah, Pugh, Cheryl, Buckner, Michelle, Chowdhury, Simon, Russell, J Martin, Gilson, Clare, Rush, Hannah, Bowen, Jo, Lydon, Anna, Pedley, Ian, O'Sullivan, Joe M, Birtle, Alison, Gale, Joanna, Srihari, Narayanan, Thomas, Carys, Wagstaff, John, Gray, Emma, Alzoueb, Mymoona, Parikh, Omi, Robinson, Angus, Syndikus, Isabel, Wylie, James, Thalmann, George, de Bono, Johann S, Dearnaley, David P, Mason, Malcolm D, Gilbert, Duncan, Langley, Ruth E, Millman, Robin, Matheson, David, Sydes, Matthew R, Brown, Louise C, Parmar, Mahesh K B, and James, Nicholas D
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- 2022
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15. Toxicity and Surgical Complication Rates of Neoadjuvant Atezolizumab in Patients with Muscle-invasive Bladder Cancer Undergoing Radical Cystectomy: Updated Safety Results from the ABACUS Trial
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Szabados, Bernadett, Rodriguez-Vida, Alejo, Durán, Ignacio, Crabb, Simon J., Van Der Heijden, Michiel S., Pous, Albert Font, Gravis, Gwenaelle, Herranz, Urbano Anido, Protheroe, Andrew, Ravaud, Alain, Maillet, Denis, Mendez-Vidal, Maria J., Suárez, Cristina, Linch, Mark, Prendergast, Aaron, Tyson, Charlotte, Mousa, Kelly, Castellano, Daniel, and Powles, Thomas
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- 2021
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16. Real world, multicentre patterns of treatment and survival in metastatic renal cell carcinoma with the UK Renal Oncology Collaborative (UK ROC): Is it time to look favourably on first‐line immunotherapy containing combinations in all IMDC groups?
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McGrane, John, Frazer, Ricky, Challapalli, Amarnath, Ratnayake, Gihan, Boh, Zhaung, Clayton, Alison, Chau, Caroline, Sharma, Anand, Elgendy, Manal, Charnley, Natalie, Mohamed, Wael, Kingdon, Sarah, Protheroe, Andrew, Lydon, Anna, Halstead, Anna, Ford, Vicky, Muazzam, Iqtedar, Lee, Dawn, Melendez‐Torres, G. J., and Bahl, Amit
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RENAL cell carcinoma ,PROPORTIONAL hazards models ,IMMUNOTHERAPY ,PROTEIN-tyrosine kinase inhibitors - Abstract
Introduction: Clinical trials show improved progression‐free survival (PFS) and overall survival (OS) in first‐line metastatic renal cell carcinoma (mRCC) patients with immunotherapy containing systemic anti‐cancer therapies (SACT). However, in the favourable international metastatic renal cell cancer database consortium (IMDC) group there is no trial evidence for OS benefit despite clear PFS improvement when comparing anti‐VEGF tyrosine kinase inhibitor (TKI) monotherapy and (immunotherapy and TKI) IO/TKI combinations. Objective: To assess the impact of first‐line SACT choice on the clinical outcomes of PFS and OS in mRCC. To evaluate this impact of initial SACT for allcomers and the favourable IMDC group. Methods: A multicentre retrospective review of patients who started SACT for mRCC (01/01/2018–30/06/2021) at 17 UK NHS trusts. Patient demographics and IMDC group were analysed. Survival data were compared using Kaplan–Meier curves, and the statistical significance of differences in outcome between the groups was assessed with the log‐rank test. Univariable and multivariable Cox proportional hazard modelling estimate the hazard ratios (HRs) for survival outcomes associated with IMDC and treatment subtype. Results: One thousand three hundred and nineteen patients were identified with a median age of 64. 294 (22.3%), 695 (52.7%) and 321 (24.3%) were IMDC group favourable, intermediate and poor, respectively. 311 (23.6%), 197 (14.9%) and 778 (59%) patients received checkpoint inhibitor and anti‐CTLA4 monoclonal antibody (IO/IO), IO/TKI and TKI first‐line SACT across all IMDC groups. Significant PFS improvement favouring IO/TKI versus TKI was demonstrated in allcomers HR = 0.61. In the favourable risk group, Log rank testing demonstrated a significant benefit for IO/TKI over TKI for PFS (HR = 0.60, 95% CI [0.39, 0.91]) and OS (HR = 0.42, 95% CI [0.18, 0.99]). Conclusion: In this real‐world evidence cohort, we have shown OS and PFS benefit with IO/TKI versus TKI in the favourable IMDC risk group. This has not been previously reported from trial outcomes and would support use of front‐line IO/TKI in mRCC favourable risk patients. [ABSTRACT FROM AUTHOR]
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- 2024
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17. The WIRE study a phase II, multi-arm, multi-centre, non-randomised window-of-opportunity clinical trial platform using a Bayesian adaptive design for proof-of-mechanism of novel treatment strategies in operable renal cell cancer – a study protocol
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Ursprung, Stephan, Mossop, Helen, Gallagher, Ferdia A., Sala, Evis, Skells, Richard, Sipple, Jamal A. N., Mitchell, Thomas J., Chhabra, Anita, Fife, Kate, Matakidou, Athena, Young, Gemma, Walker, Amanda, Thomas, Martin G., Ortuzar, Mireia Crispin, Sullivan, Mark, Protheroe, Andrew, Oades, Grenville, Venugopal, Balaji, Warren, Anne Y., Stone, John, Eisen, Tim, Wason, James, Welsh, Sarah J., and Stewart, Grant D.
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- 2021
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18. Immune checkpoint inhibitor-related colitis assessment and prognosis: can IBD scoring point the way?
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Cheung, Vincent Ting Fung, Gupta, Tarun, Olsson-Brown, Anna, Subramanian, Sreedhar, Sasson, Sarah Christina, Heseltine, Jonathan, Fryer, Eve, Collantes, Elena, Sacco, Joseph J., Pirmohamed, Munir, Simmons, Alison, Klenerman, Paul, Tuthill, Mark, Protheroe, Andrew S., Chitnis, Meenali, Fairfax, Benjamin Peter, Payne, Miranda Jane, Middleton, Mark Ross, and Brain, Oliver
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- 2020
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19. DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer
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Mateo, Joaquin, Carreira, Suzanne, Sandhu, Shahneen, Miranda, Susana, Mossop, Helen, Perez-Lopez, Raquel, Nava Rodrigues, Daniel, Robinson, Dan, Omlin, Aurelius, Tunariu, Nina, Boysen, Gunther, Porta, Nuria, Flohr, Penny, Gillman, Alexa, Figueiredo, Ines, Paulding, Claire, Seed, George, Jain, Suneil, Ralph, Christy, Protheroe, Andrew, Hussain, Syed, Jones, Robert, Elliott, Tony, McGovern, Ursula, Bianchini, Diletta, Goodall, Jane, Zafeiriou, Zafeiris, Williamson, Chris T, Ferraldeschi, Roberta, Riisnaes, Ruth, Ebbs, Bernardette, Fowler, Gemma, Roda, Desamparados, Yuan, Wei, Wu, Yi-Mi, Cao, Xuhong, Brough, Rachel, Pemberton, Helen, A'Hern, Roger, Swain, Amanda, Kunju, Lakshmi P, Eeles, Rosalind, Attard, Gerhardt, Lord, Christopher J, Ashworth, Alan, Rubin, Mark A, Knudsen, Karen E, Feng, Felix Y, Chinnaiyan, Arul M, Hall, Emma, and de Bono, Johann S
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Genetics ,Urologic Diseases ,Human Genome ,Prostate Cancer ,Cancer ,Clinical Research ,6.1 Pharmaceuticals ,6.2 Cellular and gene therapies ,Evaluation of treatments and therapeutic interventions ,4.1 Discovery and preclinical testing of markers and technologies ,Detection ,screening and diagnosis ,Adult ,Aged ,Anemia ,Antineoplastic Agents ,Ataxia Telangiectasia Mutated Proteins ,DNA Repair ,Drug Resistance ,Neoplasm ,Enzyme Inhibitors ,Fatigue ,Genes ,BRCA2 ,Genes ,Tumor Suppressor ,Humans ,Male ,Middle Aged ,Mutation ,Neoplasm Metastasis ,Phthalazines ,Piperazines ,Poly(ADP-ribose) Polymerase Inhibitors ,Prostatic Neoplasms ,Medical and Health Sciences ,General & Internal Medicine - Abstract
BackgroundProstate cancer is a heterogeneous disease, but current treatments are not based on molecular stratification. We hypothesized that metastatic, castration-resistant prostate cancers with DNA-repair defects would respond to poly(adenosine diphosphate [ADP]-ribose) polymerase (PARP) inhibition with olaparib.MethodsWe conducted a phase 2 trial in which patients with metastatic, castration-resistant prostate cancer were treated with olaparib tablets at a dose of 400 mg twice a day. The primary end point was the response rate, defined either as an objective response according to Response Evaluation Criteria in Solid Tumors, version 1.1, or as a reduction of at least 50% in the prostate-specific antigen level or a confirmed reduction in the circulating tumor-cell count from 5 or more cells per 7.5 ml of blood to less than 5 cells per 7.5 ml. Targeted next-generation sequencing, exome and transcriptome analysis, and digital polymerase-chain-reaction testing were performed on samples from mandated tumor biopsies.ResultsOverall, 50 patients were enrolled; all had received prior treatment with docetaxel, 49 (98%) had received abiraterone or enzalutamide, and 29 (58%) had received cabazitaxel. Sixteen of 49 patients who could be evaluated had a response (33%; 95% confidence interval, 20 to 48), with 12 patients receiving the study treatment for more than 6 months. Next-generation sequencing identified homozygous deletions, deleterious mutations, or both in DNA-repair genes--including BRCA1/2, ATM, Fanconi's anemia genes, and CHEK2--in 16 of 49 patients who could be evaluated (33%). Of these 16 patients, 14 (88%) had a response to olaparib, including all 7 patients with BRCA2 loss (4 with biallelic somatic loss, and 3 with germline mutations) and 4 of 5 with ATM aberrations. The specificity of the biomarker suite was 94%. Anemia (in 10 of the 50 patients [20%]) and fatigue (in 6 [12%]) were the most common grade 3 or 4 adverse events, findings that are consistent with previous studies of olaparib.ConclusionsTreatment with the PARP inhibitor olaparib in patients whose prostate cancers were no longer responding to standard treatments and who had defects in DNA-repair genes led to a high response rate. (Funded by Cancer Research UK and others; ClinicalTrials.gov number, NCT01682772; Cancer Research UK number, CRUK/11/029.).
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- 2015
20. Abiraterone acetate plus prednisone in patients with newly diagnosed high-risk metastatic castration-sensitive prostate cancer (LATITUDE): final overall survival analysis of a randomised, double-blind, phase 3 trial
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Fizazi, Karim, Tran, NamPhuong, Fein, Luis, Matsubara, Nobuaki, Rodriguez-Antolin, Alfredo, Alekseev, Boris Y, Özgüroğlu, Mustafa, Ye, Dingwei, Feyerabend, Susan, Protheroe, Andrew, Sulur, Giri, Luna, Yesenia, Li, Susan, Mundle, Suneel, and Chi, Kim N
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- 2019
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21. The diagnostic performance of current tumour markers in surveillance for recurrent testicular cancer: A diagnostic test accuracy systematic review
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Nicholson, Brian D., Jones, Nicholas R., Protheroe, Andrew, Joseph, Johnson, Roberts, Nia W., Van den Bruel, Ann, and Fanshawe, Thomas R.
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- 2019
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22. Addition of Docetaxel to First-line Long-term Hormone Therapy in Prostate Cancer (STAMPEDE): Modelling to Estimate Long-term Survival, Quality-adjusted Survival, and Cost-effectiveness
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Woods, Beth S., Sideris, Eleftherios, Sydes, Matthew R., Gannon, Melissa R., Parmar, Mahesh K.B., Alzouebi, Mymoona, Attard, Gerhardt, Birtle, Alison J., Brock, Susannah, Cathomas, Richard, Chakraborti, Prabir R., Cook, Audrey, Cross, William R., Dearnaley, David P., Gale, Joanna, Gibbs, Stephanie, Graham, John D., Hughes, Robert, Jones, Rob J., Laing, Robert, Mason, Malcolm D., Matheson, David, McLaren, Duncan B., Millman, Robin, O'Sullivan, Joe M., Parikh, Omi, Parker, Christopher C., Peedell, Clive, Protheroe, Andrew, Ritchie, Alastair W.S., Robinson, Angus, Russell, J. Martin, Simms, Matthew S., Srihari, Narayanan N., Srinivasan, Rajaguru, Staffurth, John N., Sundar, Santhanam, Thalmann, George N., Tolan, Shaun, Tran, Anna T.H., Tsang, David, Wagstaff, John, James, Nicholas D., and Sculpher, Mark J.
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- 2018
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23. From Clinical Trials to Real-life Clinical Practice: The Role of Immunotherapy with PD-1/PD-L1 Inhibitors in Advanced Urothelial Carcinoma
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Hussain, Syed A., Birtle, Alison, Crabb, Simon, Huddart, Robert, Small, Diane, Summerhayes, Maxwell, Jones, Robert, and Protheroe, Andrew
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- 2018
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24. Changing Practice Evaluation—Stage 1 Seminoma: Outcomes With Adjuvant Treatment Versus Surveillance: Risk Factors for Recurrence and Optimizing Follow-up Protocols—Experience From a Supraregional Center
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Tyrrell, Helen E.J., Church, David N., Joseph, Johnson, Traill, Zoe C., Sullivan, Mark E., Tuthill, Mark H., Verrill, Clare L., Pintus, Elias P., Dallas, Nicola L., Rogers, Paul B., Redgwell, Jacqueline, and Protheroe, Andrew S.
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- 2018
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25. Clinical efficacy and biomarker analysis of neoadjuvant atezolizumab in operable urothelial carcinoma in the ABACUS trial
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Powles, Thomas, Kockx, Mark, Rodriguez-Vida, Alejo, Duran, Ignacio, Crabb, Simon J., Van Der Heijden, Michiel S., Szabados, Bernadett, Pous, Albert Font, Gravis, Gwenaelle, Herranz, Urbano Anido, Protheroe, Andrew, Ravaud, Alain, Maillet, Denis, Mendez, Maria Jose, Suarez, Cristina, Linch, Mark, Prendergast, Aaron, van Dam, Pieter-Jan, Stanoeva, Diana, Daelemans, Sofie, Mariathasan, Sanjeev, Tea, Joy S., Mousa, Kelly, Banchereau, Romain, and Castellano, Daniel
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- 2019
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26. Value of Supraregional Multidisciplinary Review for the Contemporary Management of Testicular Tumors
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Purshouse, Karin, Watson, Robert A., Church, David N., Richardson, Charlotte, Crane, Gemma, Traill, Zoe, Sullivan, Mark, Roberts, Ian, Browning, Lisa, Turner, Gareth, Parameshwaran, Vishnu, Johnson, Joseph, Chitnis, Meenali, Protheroe, Andrew, and Verrill, Clare
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- 2017
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27. Development of a best-practice clinical guideline for the use of bleomycin in the treatment of germ cell tumours in the UK
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Watson, Robert A., De La Peña, Hugo, Tsakok, Maria T., Joseph, Johnson, Stoneham, Sara, Shamash, Jonathan, Joffe, Johnathan, Mazhar, Danish, Traill, Zoe, Ho, Ling-Pei, Brand, Sue, and Protheroe, Andrew S.
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- 2018
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28. Prostatic Artery Embolization (PAE) for Benign Prostatic Hyperplasia (BPH) with Haematuria in the Absence of an Upper Urinary Tract Pathology
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Tapping, Charles R., Macdonald, Andrew, Hadi, Mo, Mortensen, Chloe, Crew, Jeremy, Protheroe, Andrew, Little, Mark W., and Boardman, Phil
- Published
- 2018
- Full Text
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29. Addition of docetaxel, zoledronic acid, or both to first-line long-term hormone therapy in prostate cancer (STAMPEDE): survival results from an adaptive, multiarm, multistage, platform randomised controlled trial
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James, Nicholas D, Sydes, Matthew R, Clarke, Noel W, Mason, Malcolm D, Dearnaley, David P, Spears, Melissa R, Ritchie, Alastair W S, Parker, Christopher C, Russell, J Martin, Attard, Gerhardt, de Bono, Johann, Cross, William, Jones, Rob J, Thalmann, George, Amos, Claire, Matheson, David, Millman, Robin, Alzouebi, Mymoona, Beesley, Sharon, Birtle, Alison J, Brock, Susannah, Cathomas, Richard, Chakraborti, Prabir, Chowdhury, Simon, Cook, Audrey, Elliott, Tony, Gale, Joanna, Gibbs, Stephanie, Graham, John D, Hetherington, John, Hughes, Robert, Laing, Robert, McKinna, Fiona, McLaren, Duncan B, O'Sullivan, Joe M, Parikh, Omi, Peedell, Clive, Protheroe, Andrew, Robinson, Angus J, Srihari, Narayanan, Srinivasan, Rajaguru, Staffurth, John, Sundar, Santhanam, Tolan, Shaun, Tsang, David, Wagstaff, John, and Parmar, Mahesh K B
- Published
- 2016
- Full Text
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30. Everolimus versus sunitinib for patients with metastatic non-clear cell renal cell carcinoma (ASPEN): a multicentre, open-label, randomised phase 2 trial
- Author
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Armstrong, Andrew J, Halabi, Susan, Eisen, Tim, Broderick, Samuel, Stadler, Walter M, Jones, Robert J, Garcia, Jorge A, Vaishampayan, Ulka N, Picus, Joel, Hawkins, Robert E, Hainsworth, John D, Kollmannsberger, Christian K, Logan, Theodore F, Puzanov, Igor, Pickering, Lisa M, Ryan, Christopher W, Protheroe, Andrew, Lusk, Christine M, Oberg, Sadie, and George, Daniel J
- Published
- 2016
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31. Case report of oxalate nephropathy in a patient with pancreatic metastases from renal carcinoma
- Author
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Purshouse, Karin, Chamberlain, Sarah, Soares, Maria, Tuthill, Mark, Protheroe, Andrew, and Mole, David R.
- Published
- 2019
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32. Anti-PD-L1 atezolizumab-Induced Autoimmune Diabetes: a Case Report and Review of the Literature
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Hickmott, Laura, De La Peña, Hugo, Turner, Helen, Ahmed, Fathelrahman, Protheroe, Andrew, Grossman, Ashley, and Gupta, Avinash
- Published
- 2017
- Full Text
- View/download PDF
33. Publisher Correction: Clinical efficacy and biomarker analysis of neoadjuvant atezolizumab in operable urothelial carcinoma in the ABACUS trial
- Author
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Powles, Thomas, Kockx, Mark, Rodriguez-Vida, Alejo, Duran, Ignacio, Crabb, Simon J., Van Der Heijden, Michiel S., Szabados, Bernadett, Pous, Albert Font, Gravis, Gwenaelle, Herranz, Urbano Anido, Protheroe, Andrew, Ravaud, Alain, Maillet, Denis, Mendez, Maria Jose, Suarez, Cristina, Linch, Mark, Prendergast, Aaron, van Dam, Pieter-Jan, Stanoeva, Diana, Daelemans, Sofie, Mariathasan, Sanjeev, Tea, Joy S., Mousa, Kelly, Banchereau, Romain, and Castellano, Daniel
- Published
- 2020
- Full Text
- View/download PDF
34. Activity and safety of ODM-201 in patients with progressive metastatic castration-resistant prostate cancer (ARADES): an open-label phase 1 dose-escalation and randomised phase 2 dose expansion trial
- Author
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Fizazi, Karim, Massard, Christophe, Bono, Petri, Jones, Robert, Kataja, Vesa, James, Nicholas, Garcia, Jorge A, Protheroe, Andrew, Tammela, Teuvo L, Elliott, Tony, Mattila, Leena, Aspegren, John, Vuorela, Annamari, Langmuir, Peter, and Mustonen, Mika
- Published
- 2014
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- View/download PDF
35. Genomic Evolution and Transcriptional Changes in the Evolution of Prostate Cancer into Neuroendocrine and Ductal Carcinoma Types.
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Rao, Srinivasa R., Protheroe, Andrew, Cerundolo, Lucia, Maldonado-Perez, David, Browning, Lisa, Lamb, Alastair D., Bryant, Richard J., Mills, Ian G., Woodcock, Dan J., Hamdy, Freddie C., Tomlinson, Ian P. M., and Verrill, Clare
- Subjects
- *
DUCTAL carcinoma , *NEUROENDOCRINE tumors , *PROSTATE cancer , *SMALL cell carcinoma , *CANCER relapse , *ANDROGEN receptors , *BREAST - Abstract
Prostate cancer is typically of acinar adenocarcinoma type but can occasionally present as neuroendocrine and/or ductal type carcinoma. These are associated with clinically aggressive disease, and the former often arises on a background of androgen deprivation therapy, although it can also arise de novo. Two prostate cancer cases were sequenced by exome capture from archival tissue. Case 1 was de novo small cell neuroendocrine carcinoma and ductal adenocarcinoma with three longitudinal samples over 5 years. Case 2 was a single time point after the development of treatment-related neuroendocrine prostate carcinoma. Case 1 showed whole genome doubling in all samples and focal amplification of AR in all samples except the first time point. Phylogenetic analysis revealed a common ancestry for ductal and small cell carcinoma. Case 2 showed 13q loss (involving RB1) in both adenocarcinoma and small cell carcinoma regions, and 3p gain, 4p loss, and 17p loss (involving TP53) in the latter. By using highly curated samples, we demonstrate for the first time that small-cell neuroendocrine and ductal prostatic carcinoma can have a common ancestry. We highlight whole genome doubling in a patient with prostate cancer relapse, reinforcing its poor prognostic nature. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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36. Dismantling the present and future threats of testicular cancer: a grounded theory of positive and negative adjustment trajectories
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Matheson, Lauren, Boulton, Mary, Lavender, Verna, Protheroe, Andrew, Brand, Sue, Wanat, Marta, and Watson, Eila
- Published
- 2016
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37. PemBla: A Phase 1 study of intravesical pembrolizumab in recurrent non‐muscle‐invasive bladder cancer.
- Author
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Woodcock, Victoria K., Chen, Ji‐Li, Purshouse, Karin, Butcher, Chrissie, Collins, Linda, Haddon, Caroline, Verrall, Gillian, Elhussein, Leena, Roberts, Corran, Tarlton, Andrea, Rei, Margarida, Napolitani, Giorgio, Salio, Mariolina, Middleton, Mark R., Cerundolo, Vincenzo, Crew, Jeremy, and Protheroe, Andrew S.
- Published
- 2023
- Full Text
- View/download PDF
38. Celecoxib plus hormone therapy versus hormone therapy alone for hormone-sensitive prostate cancer: first results from the STAMPEDE multiarm, multistage, randomised controlled trial
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James, Nicholas D, Sydes, Matthew R, Mason, Malcolm D, Clarke, Noel W, Anderson, John, Dearnaley, David P, Dwyer, John, Jovic, Gordana, Ritchie, Alastair WS, Russell, J Martin, Sanders, Karen, Thalmann, George N, Bertelli, Gianfilippo, Birtle, Alison J, O'Sullivan, Joe M, Protheroe, Andrew, Sheehan, Denise, Srihari, Narayanan, and Parmar, Mahesh KB
- Published
- 2012
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39. Cediranib monotherapy in patients with advanced renal cell carcinoma: Results of a randomised phase II study
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Mulders, Peter, Hawkins, Robert, Nathan, Paul, de Jong, Igle, Osanto, Susanne, Porfiri, Emilio, Protheroe, Andrew, van Herpen, Carla M.L., Mookerjee, Bijoyesh, Pike, Laura, Jürgensmeier, Juliane M., and Gore, Martin E.
- Published
- 2012
- Full Text
- View/download PDF
40. An adult Xp11.2 translocation renal carcinoma showing response to treatment with sunitinib
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Pwint, Thinn P., Macaulay, Valentine, Roberts, Ian S.D., Sullivan, Mark, and Protheroe, Andrew
- Published
- 2011
- Full Text
- View/download PDF
41. IMPACT OF PRIOR ENDOCRINE THERAPY ON CLINICAL BENEFIT OF ABIRATERONE ACETATE IN PATIENTS WITH CHEMOTHERAPY-NAÏVE METASTATIC CASTRATION-RESISTANT PROSTATE CANCER: RESULTS FROM COU-AA-302: MP70-11
- Author
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Saad, Fred, Kheoh, Thian, Yu, Margaret K., Smith, Matthew R., Small, Eric J., Mulders, Peter F.A., Fizazi, Karim, Rathkopf, Dana, Oudard, Stéphane, Scher, Howard I., Bellmunt, Joaquim, Taplin, Mary-Ellen, Davis, Ian D., Schrijvers, Dirk, Protheroe, Andrew, Molina, Arturo, Griffin, Thomas W., de Bono, Johann S., and Ryan, Charles J.
- Published
- 2014
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42. The Use of Digital Pathology and Artificial Intelligence in Histopathological Diagnostic Assessment of Prostate Cancer: A Survey of Prostate Cancer UK Supporters.
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Rakovic, Kai, Colling, Richard, Browning, Lisa, Dolton, Monica, Horton, Margaret R., Protheroe, Andrew, Lamb, Alastair D., Bryant, Richard J., Scheffer, Richard, Crofts, James, Stanislaus, Ewart, and Verrill, Clare
- Subjects
PROSTATE cancer ,ARTIFICIAL intelligence ,PATHOLOGY ,HISTOPATHOLOGY ,DATA security - Abstract
There has been particular interest in the deployment of digital pathology (DP) and artificial intelligence (AI) in the diagnosis of prostate cancer, but little is known about the views of the public on their use. Prostate Cancer UK supporters were invited to an online survey which included quantitative and qualitative questions exploring views on the use of DP and AI in histopathological assessment. A total of 1276 responses to the survey were analysed (response rate 12.5%). Most respondents were supportive of DP (87%, 1113/1276) and of testing AI in clinical practice as a diagnostic adjunct (83%, 1058/1276). Respondents saw DP as potentially increasing workflow efficiency, facilitating research, education/training and fostering clinical discussions between clinician and patient. Some respondents raised concerns regarding data security, reliability and the need for human oversight. Among those who were unsure about AI, information was requested regarding its performance and others wanted to defer the decision to use it to an expert. Although most are in favour of its use, some are unsure, and their concerns could be addressed with more information or better communication. A small minority (<1%) are not in favour of the testing of the use of AI in histopathology for reasons which are not easily addressed. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
43. Genomic sequencing in oncology: Considerations for integration in routine cancer care.
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Rahman, Belinda, Lamb, Alastair, Protheroe, Andrew, Shah, Ketan, Solomons, Joyce, Williams, Jonathan, and Ormondroyd, Elizabeth
- Subjects
OCCUPATIONAL roles ,SEQUENCE analysis ,HEALTH services accessibility ,PROFESSIONS ,CONFIDENCE ,HUMAN genome ,GENETIC testing ,NATIONAL health services ,GENOMICS ,HEALTH care teams ,INTEGRATED health care delivery ,CANCER patient medical care - Abstract
The article presents the discussion on integrating genomic sequencing in oncology. Topics include successful implementation of genomic medicine in routine health care identifying the need for practice reform, genomics education, and training; and healthcare professionals' viewing the implementation of genomic sequencing into NHS clinical practice reporting several concerns including lack of preparedness of nongenetics clinicians.
- Published
- 2022
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44. Active surveillance of small renal masses offers short-term oncological efficacy equivalent to radical and partial nephrectomy
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Patel, Nilay, Cranston, David, Akhtar, Zeeshan M., George, Caroline, Jones, Andrew, Leiblich, Aaron, Protheroe, Andrew, and Sullivan, Mark
- Published
- 2012
- Full Text
- View/download PDF
45. CD31 angiogenesis and combined expression of HIF-1α and HIF-2α are prognostic in primary clear-cell renal cell carcinoma (CC-RCC), but HIFα transcriptional products are not: implications for antiangiogenic trials and HIFα biomarker studies in primary CC-RCC
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Biswas, Swethajit, Charlesworth, Philip J.S., Turner, Gareth D.H., Leek, Russell, Thamboo, Paul T., Campo, Leticia, Turley, Helen, Dildey, Petra, Protheroe, Andrew, Cranston, David, Gatter, Kevin C., Pezzella, Francesco, and Harris, Adrian L.
- Published
- 2012
- Full Text
- View/download PDF
46. Accelerated methotrexate, vinblastine, doxorubicin, and cisplatin (AMVAC) as neoadjuvant chemotherapy for patients with muscle-invasive transitional cell carcinoma of the bladder
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Blick, Christopher, Hall, Peter, Pwint, Thinn, Al-Terkait, Faisal, Crew, Jeremy, Powles, Thomas, Macaulay, Valentine, Munro, Nicholas, Douglas, David, Kilbey, Neviana, Protheroe, Andrew, and Chester, John D.
- Published
- 2012
- Full Text
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47. Recent advances in urinary bladder cancer detection
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Bhatt, Jaimin, Cowan, Nigel, Protheroe, Andrew, and Crew, Jeremy
- Published
- 2012
- Full Text
- View/download PDF
48. Blastic plasmacytoid dendritic cell neoplasm presenting as a renal mass
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Prematilleke, Isha, Mohan, Vivek, Roberts, Ian, Protheroe, Andrew, and Gatter, Kevin
- Published
- 2011
- Full Text
- View/download PDF
49. Extracorporeal high intensity focused ultrasound for renal tumours: a 3-year follow-up
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Ritchie, Robert W., Leslie, Tom, Phillips, Rachel, Wu, Feng, Illing, Rowland, ter Haar, Gail, Protheroe, Andrew, and Cranston, David
- Published
- 2010
- Full Text
- View/download PDF
50. Automated uro-oncology data collection: the Cancer Research Uro-Oncology Database
- Author
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Charlesworth, Philip J.S., Kilbey, Neviana, Taylor, Marian, Leek, Russell, Cranston, David, Turner, Gareth, Crew, Jeremy, Harris, Adrian, and Protheroe, Andrew
- Published
- 2010
- Full Text
- View/download PDF
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