16 results on '"Pita, Manuel"'
Search Results
2. Evaluation of Celiac Disease by Minimally Invasive Biomarkers in a Spanish Pediatric Population.
- Author
-
Cabo del Riego, Julia María, Núñez Iglesias, María Jesús, García-Plata González, Carmen, Paz Carreira, José, Álvarez Fernández, Tamara, Dorado Díaz, Ana, Villar Mallo, Noa, Penedo Pita, Manuel, Novío Mallón, Silvia, Máiz Suárez, Lola, and Freire-Garabal Núñez, Manuel
- Published
- 2022
- Full Text
- View/download PDF
3. Digital Nomads and the Covid-19 Pandemic: Narratives About Relocation in a Time of Lockdowns and Reduced Mobility.
- Author
-
Ehn, Karine, Jorge, Ana, and Marques-Pita, Manuel
- Published
- 2022
- Full Text
- View/download PDF
4. PTPARL-D: an annotated corpus of forty-four years of Portuguese parliamentary debates.
- Author
-
Almeida, Paulo, Marques-Pita, Manuel, and Gonçalves-Sá, Joana
- Subjects
CORPORA ,PUBLIC officers ,LEGISLATIVE bodies - Abstract
In a representative democracy, some decide in the name of the rest. These elected officials are commonly gathered in public assemblies, such as parliaments, where they discuss policies, legislate, and vote on fundamental initiatives. A core aspect of such democratic processes are the plenary debates, where important public discussions take place. Many parliaments around the world are increasingly keeping the transcripts of such debates and other parliamentary data in digital formats that are accessible to the public. This is meant to increase transparency and accountability, but these records are often only provided as raw text or even as images, with little, if any, annotation and in inconsistent formats, making them difficult to analyse. Here, we present ptarl-d, an annotated corpus of debates in the Portuguese Parliament, covering the years 1976 to 2019 and representing the entire period of Portuguese democracy. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
5. Learning improvement of equipment operation by low‐cost personalized simulators to particular industrial installations.
- Author
-
Costa, Ángel M., Bouzón, Rebeca, Vergara, Diego, and Pita, Manuel
- Subjects
INSTALLATION of industrial equipment ,MARINE engineers ,MARINE engineering ,SOFTWARE engineers ,THERMODYNAMIC cycles - Abstract
Although there are different types of software resources—which in many cases favor a reduction in learning time—there are not too many options to develop a training simulator designed according to some particular real equipment. The case of the Engineering Equation Software is an effective tool that improves the learning of thermodynamics and the understanding of real thermodynamic cycles. In the present paper, an original programming procedure to improve the learning process of Marine Engineering students at the University of A Coruña (UDC) is shown. In particular, to test this learning procedure, an Operator Training Simulator is done by 117 students by the fusion of the contents of two subjects of the "Degree in Marine Technologies" of the UDC. The main advantage that this personalized simulator presents is confronting problems derived from equipment operation, thereby proving the necessary knowledge in operation based on the thermodynamic phenomena. The results showed that students who were trained with simulators showed a better understanding of the knowledge obtained. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
6. Media Literacy and Civic Cultures.
- Author
-
Pita, Manuel, Brites, Maria José, Quico, Célia, and Sousa, Carla
- Subjects
- *
MEDIA literacy , *INTEGRITY , *YOUNG adults , *EQUALITY , *PARTICIPATION , *INTERNET forums , *PSYCHOLOGY of students , *POLITICAL participation , *PUBLIC sphere , *VIRTUAL communities , *DIGITAL footprint - Published
- 2022
7. Diseño y plan de implementación para el montaje de una Oficina de Gestión de Proyectos (OGP) en MYV Consultores Asociados S.A.
- Author
-
Fernando Jiménez, José, Alejandro León, David, Sebastián Mahecha, Juan, Mauricio Manco, Jhon, and Guillermo Pita, Manuel
- Subjects
PROJECT management offices ,CORPORATE culture ,PROJECT management ,ORGANIZATIONAL structure ,COMPETITIVE advantage in business - Abstract
Copyright of Obras y Proyectos is the property of Universidad Catolica de la Santisima Concepcion and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 2019
- Full Text
- View/download PDF
8. Early and Real-Time Detection of Seasonal Influenza Onset.
- Author
-
Won, Miguel, Marques-Pita, Manuel, Louro, Carlota, and Gonçalves-Sá, Joana
- Subjects
- *
INFLUENZA statistics , *INFLUENZA diagnosis , *PREVENTION of epidemics , *MEDICAL care , *SEASONAL variations of diseases - Abstract
Every year, influenza epidemics affect millions of people and place a strong burden on health care services. A timely knowledge of the onset of the epidemic could allow these services to prepare for the peak. We present a method that can reliably identify and signal the influenza outbreak. By combining official Influenza-Like Illness (ILI) incidence rates, searches for ILI-related terms on Google, and an on-call triage phone service, Saúde 24, we were able to identify the beginning of the flu season in 8 European countries, anticipating current official alerts by several weeks. This work shows that it is possible to detect and consistently anticipate the onset of the flu season, in real-time, regardless of the amplitude of the epidemic, with obvious advantages for health care authorities. We also show that the method is not limited to one country, specific region or language, and that it provides a simple and reliable signal that can be used in early detection of other seasonal diseases. [ABSTRACT FROM AUTHOR]
- Published
- 2017
- Full Text
- View/download PDF
9. Community identities under perturbation: COVID-19 and the r/digitalnomad subreddit.
- Author
-
Pita, Manuel, Ehn, Karine, and dos Santos, Thiago
- Subjects
GROUP identity ,IDENTITY (Psychology) ,TELEMATICS ,COVID-19 ,TRAVEL restrictions ,COMMUNITIES - Abstract
Digital nomads (DNs) are hyper-mobile, location-independent workers whose practices blur traditional boundaries between labour, leisure, home and travel. They rely on digital tools to work and on computer-mediated communication to share knowledge and resources. Their resource-sharing culture is vital for self-efficacy and self-actualisation -- two fundamental values that define the DN identity. Community identity is a constant social-semiotic construct mutually determined by (micro) interactions and the (macro) influence of collectively shared meanings and symbols. However, most of our understanding of community identity comes from structural and synchronic properties that often assume identity "exists" as an entity, separate from underlying collective dynamics. In this paper, we approach community identity diachronically, by introducing a quantitative typology that projects conversational timelines on two dimensions relevant to understanding the process of community identity construction: (a) the temporal orientation to the community core (or peripheral) conversation topics, and (b) interaction pattern anomalies. We cast three years of r/digitalnomad threads as a set of conversation topics, describing the interaction dynamics on these topics using the proposed typology. The central questions asked by this paper are whether there was a pre-pandemic stable community expression, and if so, how the COVID-19 pandemic may have perturbed it. Since lockdowns and travel restrictions impinged on fundamental DN values, the nature of the topics and interaction patterns that characterise the r/digitalnomad subreddit could have changed its character. We found a stable pre-pandemic balanced expression of core and peripheral conversation topics with regular interaction patterns. This identity expression was perturbed temporarily in the middle of the lockdown period when the community shifted focus to interactions about visa issues. As many countries began to re-open their borders around May 2021, a record-breaking number of interactions disrupted identity expression more profoundly. First, we observed constant interaction anomalies. Second, the community orientation revealed multi-factorial emergent issues, most of which revolved around conversations about what it means to be a DN, resource sharing and restrictions. We hypothesise that an influx of outsiders may have caused a clash of social norms and triggered a transformation of the DN identity that was still ongoing at the end of the studied period, in December 2021. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
10. Adaptive developmental plasticity: Compartmentalized responses to environmental cues and to corresponding internal signals provide phenotypic flexibility.
- Author
-
Mateus, Ana Rita A, Marques-Pita, Manuel, Oostra, Vicencio, Lafuente, Elvira, Brakefield, Paul M, Zwaan, Bas J, and Beldade, Patrícia
- Abstract
Background: The environmental regulation of development can result in the production of distinct phenotypes from the same genotype and provide the means for organisms to cope with environmental heterogeneity. The effect of the environment on developmental outcomes is typically mediated by hormonal signals which convey information about external cues to the developing tissues. While such plasticity is a wide-spread property of development, not all developing tissues are equally plastic. To understand how organisms integrate environmental input into coherent adult phenotypes, we must know how different body parts respond, independently or in concert, to external cues and to the corresponding internal signals. Results: We quantified the effect of temperature and ecdysone hormone manipulations on post-growth tissue patterning in an experimental model of adaptive developmental plasticity, the butterfly Bicyclus anynana. Following a suite of traits evolving by natural or sexual selection, we found that different groups of cells within the same tissue have sensitivities and patterns of response that are surprisingly distinct for the external environmental cue and for the internal hormonal signal. All but those wing traits presumably involved in mate choice responded to developmental temperature and, of those, all but the wing traits not exposed to predators responded to hormone manipulations. On the other hand, while patterns of significant response to temperature contrasted traits on autonomously-developing wings, significant response to hormone manipulations contrasted neighboring groups of cells with distinct color fates. We also showed that the spatial compartmentalization of these responses cannot be explained by the spatial or temporal compartmentalization of the hormone receptor protein. Conclusions: Our results unravel the integration of different aspects of the adult phenotype into developmental and functional units which both reflect and impact evolutionary change. Importantly, our findings underscore the complexity of the interactions between environment and physiology in shaping the development of different body parts. [ABSTRACT FROM AUTHOR]
- Published
- 2014
- Full Text
- View/download PDF
11. Canalization and Control in Automata Networks: Body Segmentation in Drosophila melanogaster.
- Author
-
Marques-Pita, Manuel and Rocha, Luis M.
- Subjects
- *
DROSOPHILA as laboratory animals , *CELLULAR signal transduction , *COMPUTATIONAL biology , *SYSTEMS biology , *CELL differentiation , *GENETIC regulation , *STOCHASTIC analysis , *MACHINE theory - Abstract
We present schema redescription as a methodology to characterize canalization in automata networks used to model biochemical regulation and signalling. In our formulation, canalization becomes synonymous with redundancy present in the logic of automata. This results in straightforward measures to quantify canalization in an automaton (micro-level), which is in turn integrated into a highly scalable framework to characterize the collective dynamics of large-scale automata networks (macro-level). This way, our approach provides a method to link micro- to macro-level dynamics – a crux of complexity. Several new results ensue from this methodology: uncovering of dynamical modularity (modules in the dynamics rather than in the structure of networks), identification of minimal conditions and critical nodes to control the convergence to attractors, simulation of dynamical behaviour from incomplete information about initial conditions, and measures of macro-level canalization and robustness to perturbations. We exemplify our methodology with a well-known model of the intra- and inter cellular genetic regulation of body segmentation in Drosophila melanogaster. We use this model to show that our analysis does not contradict any previous findings. But we also obtain new knowledge about its behaviour: a better understanding of the size of its wild-type attractor basin (larger than previously thought), the identification of novel minimal conditions and critical nodes that control wild-type behaviour, and the resilience of these to stochastic interventions. Our methodology is applicable to any complex network that can be modelled using automata, but we focus on biochemical regulation and signalling, towards a better understanding of the (decentralized) control that orchestrates cellular activity – with the ultimate goal of explaining how do cells and tissues ‘compute’. [ABSTRACT FROM AUTHOR]
- Published
- 2013
- Full Text
- View/download PDF
12. Canalization and Control in Automata Networks: Body Segmentation in Drosophila melanogaster.
- Author
-
Marques-Pita, Manuel and Rocha, Luis M.
- Subjects
DROSOPHILA as laboratory animals ,CELLULAR signal transduction ,COMPUTATIONAL biology ,SYSTEMS biology ,CELL differentiation ,GENETIC regulation ,STOCHASTIC analysis ,MACHINE theory - Abstract
We present schema redescription as a methodology to characterize canalization in automata networks used to model biochemical regulation and signalling. In our formulation, canalization becomes synonymous with redundancy present in the logic of automata. This results in straightforward measures to quantify canalization in an automaton (micro-level), which is in turn integrated into a highly scalable framework to characterize the collective dynamics of large-scale automata networks (macro-level). This way, our approach provides a method to link micro- to macro-level dynamics – a crux of complexity. Several new results ensue from this methodology: uncovering of dynamical modularity (modules in the dynamics rather than in the structure of networks), identification of minimal conditions and critical nodes to control the convergence to attractors, simulation of dynamical behaviour from incomplete information about initial conditions, and measures of macro-level canalization and robustness to perturbations. We exemplify our methodology with a well-known model of the intra- and inter cellular genetic regulation of body segmentation in Drosophila melanogaster. We use this model to show that our analysis does not contradict any previous findings. But we also obtain new knowledge about its behaviour: a better understanding of the size of its wild-type attractor basin (larger than previously thought), the identification of novel minimal conditions and critical nodes that control wild-type behaviour, and the resilience of these to stochastic interventions. Our methodology is applicable to any complex network that can be modelled using automata, but we focus on biochemical regulation and signalling, towards a better understanding of the (decentralized) control that orchestrates cellular activity – with the ultimate goal of explaining how do cells and tissues ‘compute’. [ABSTRACT FROM AUTHOR]
- Published
- 2013
- Full Text
- View/download PDF
13. Increased serum levels of interleukin-2 and soluble interleukin-2 receptor in celiac disease.
- Author
-
Penedo-Pita, Manuel, Peteiro-Cartelle, Javier, Penedo-Pita, M, and Peteiro-Cartelle, J
- Published
- 1991
14. IoT and Engagement in the Ubiquitous Museum.
- Author
-
Pierdicca, Roberto, Marques-Pita, Manuel, Paolanti, Marina, and Malinverni, Eva Savina
- Subjects
- *
INTERNET of things , *UBIQUITOUS computing , *SENSOR networks , *PRINCIPAL components analysis , *MUSEUM visitors - Abstract
In increasingly hyper-connected societies, where individuals rely on short and fast online communications to consume information, museums face a significant survival challenge. Collaborations between scientists and museums suggest that the use of the technological framework known as Internet of Things (IoT) will be a key player in tackling this challenge. IoT can be used to gather and analyse visitor generated data, leading to data-driven insights that can fuel novel, adaptive and engaging museum experiences. We used an IoT implementation—a sensor network installed in the physical space of a museum—to look at how single visitors chose to enter and spend time in the different rooms of a curated exhibition. We collected a sparse, non-overlapping dataset of individual visits. Using various statistical analyses, we found that visitor attention span was very short. People visited five out of twenty rooms on average, and spent a median of two minutes in each room. However, the patterns of choice and time spent in rooms were not random. Indeed, they could be described in terms of a set of linearly separable visit patterns we obtained using principal component analysis. These results are encouraging for future interdisciplinary research that seeks to leverage IoT to get numerical proxies for people attention inside the museum, and use this information to fuel the next generation of possible museum interactions. Such interactions will based on rich, non-intrusive and diverse IoT driven conversation, dynamically tailored to visitors. [ABSTRACT FROM AUTHOR]
- Published
- 2019
- Full Text
- View/download PDF
15. Effective connectivity determines the critical dynamics of biochemical networks.
- Author
-
Manicka S, Marques-Pita M, and Rocha LM
- Subjects
- Systems Biology
- Abstract
Living systems comprise interacting biochemical components in very large networks. Given their high connectivity, biochemical dynamics are surprisingly not chaotic but quite robust to perturbations-a feature C.H. Waddington named canalization. Because organisms are also flexible enough to evolve, they arguably operate in a critical dynamical regime between order and chaos. The established theory of criticality is based on networks of interacting automata where Boolean truth values model presence/absence of biochemical molecules. The dynamical regime is predicted using network connectivity and node bias (to be on/off) as tuning parameters. Revising this to account for canalization leads to a significant improvement in dynamical regime prediction. The revision is based on effective connectivity , a measure of dynamical redundancy that buffers automata response to some inputs. In both random and experimentally validated systems biology networks, reducing effective connectivity makes living systems operate in stable or critical regimes even though the structure of their biochemical interaction networks predicts them to be chaotic. This suggests that dynamical redundancy may be naturally selected to maintain living systems near critical dynamics, providing both robustness and evolvability. By identifying how dynamics propagates preferably via effective pathways, our approach helps to identify precise ways to design and control network models of biochemical regulation and signalling.
- Published
- 2022
- Full Text
- View/download PDF
16. Canalization and control in automata networks: body segmentation in Drosophila melanogaster.
- Author
-
Marques-Pita M and Rocha LM
- Subjects
- Animals, Drosophila melanogaster, Body Patterning physiology, Models, Biological
- Abstract
We present schema redescription as a methodology to characterize canalization in automata networks used to model biochemical regulation and signalling. In our formulation, canalization becomes synonymous with redundancy present in the logic of automata. This results in straightforward measures to quantify canalization in an automaton (micro-level), which is in turn integrated into a highly scalable framework to characterize the collective dynamics of large-scale automata networks (macro-level). This way, our approach provides a method to link micro- to macro-level dynamics--a crux of complexity. Several new results ensue from this methodology: uncovering of dynamical modularity (modules in the dynamics rather than in the structure of networks), identification of minimal conditions and critical nodes to control the convergence to attractors, simulation of dynamical behaviour from incomplete information about initial conditions, and measures of macro-level canalization and robustness to perturbations. We exemplify our methodology with a well-known model of the intra- and inter cellular genetic regulation of body segmentation in Drosophila melanogaster. We use this model to show that our analysis does not contradict any previous findings. But we also obtain new knowledge about its behaviour: a better understanding of the size of its wild-type attractor basin (larger than previously thought), the identification of novel minimal conditions and critical nodes that control wild-type behaviour, and the resilience of these to stochastic interventions. Our methodology is applicable to any complex network that can be modelled using automata, but we focus on biochemical regulation and signalling, towards a better understanding of the (decentralized) control that orchestrates cellular activity--with the ultimate goal of explaining how do cells and tissues 'compute'.
- Published
- 2013
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.