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• MSJC and Canadian codes provide unsafe shear strength predictions for PG-RM walls. • A modified MSJC equation is proposed to improve shear strength predictions. • A normalized shear demand parameter is a better damage indicator than story-drift ratio. • Bond-beam PG-RM walls present lower deformation capacity than bed-joint PG-RM walls. This paper presents a study on the in-plane shear response of partially-grouted reinforced masonry walls with bond-beam reinforcement. A database of 95 tests on partially-grouted walls made of concrete hollow blocks was compiled from experimental studies reported in the literature to characterize the capacity and damageability of walls subjected to in-plane lateral loading. The database has been used to evaluate the accuracy of existing design shear strength equations for partially-grouted walls. It is concluded that the shear strength expressions in the Masonry Standards Joint Committee (MSJC) code and Canadian standard are unconservative for partially-grouted walls. A modified equation based on the MSJC expression is proposed which better estimates the shear strength of this type of walls. Seismic fragility functions are also derived based on the experimental database to calculate the probability of experiencing moderate and severe damage in a partially-grouted wall for a given story-drift ratio deformation or normalized shear force demand. The resulting fragility functions show that the normalized shear demand is better correlated with the level of damage than the story-drift ratio. [ABSTRACT FROM AUTHOR]