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This study aims to analyse a single-centre cohort series of patients who underwent parotidectomy for primary malignant parotid tumours. A retrospective chart review of 64 consecutive patients treated from November 2010 to March 2022 was performed. Outcomes were analysed by Kaplan-Meier curves. Sixty-four patients with a primary parotid malignancy were included in the study, with one bilateral case in this cohort. Patients were classified as stage I–II in 39 cases and stage III–IV in 26 cases. The five-year overall survival (OS), disease-specific survival (DSS), local relapse-free survival (LRFS), and distant metastasis-free survival (DMFS) rates were 78.4%, 89%, 92.5%, and 87.1%, respectively. Univariate analysis showed that high-risk histology, stage IV disease, lymphovascular invasion, perineural invasion, node metastasis, skin involvement, facial nerve involvement, and positive or close margins were risk factors associated with poorer outcomes. At present, the best evidence suggests that radical surgery should be the standard approach, and adjuvant therapy, in terms of radiotherapy/chemoradiotherapy, is recommended in patients with risk factors.

This study aims to analyse a single-centre cohort series of patients who underwent parotidectomy for primary malignant parotid tumours. A retrospective chart review of 64 consecutive patients treated from November 2010 to March 2022 was performed. Outcomes were analysed by Kaplan-Meier curves. Sixty-four patients with a primary parotid malignancy were included in the study, with one bilateral case in this cohort. Patients were classified as stage I–II in 39 cases and stage III–IV in 26 cases. The five-year overall survival (OS), disease-specific survival (DSS), local relapse-free survival (LRFS), and distant metastasis-free survival (DMFS) rates were 78.4%, 89%, 92.5%, and 87.1%, respectively. Univariate analysis showed that high-risk histology, stage IV disease, lymphovascular invasion, perineural invasion, node metastasis, skin involvement, facial nerve involvement, and positive or close margins were risk factors associated with poorer outcomes. At present, the best evidence suggests that radical surgery should be the standard approach, and adjuvant therapy, in terms of radiotherapy/chemoradiotherapy, is recommended in patients with risk factors. [ABSTRACT FROM AUTHOR]

Pleomorphic adenomas account for the majority of parotid masses, typically arising in the tail of the gland and enlarging slowly. Most are 2 to 6 cm in size when resected. We report the resection of a benign mixed tumour of the left parotid gland with a history of bleeding. The resected tumour measured 21 cm in diameter, weighed 1.81 kg, and on pathologic examination was a benign mixed tumour without malignant degeneration. The implications of this unusual case for the management of mixed tumours are discussed with a review of the literature

Low-grade fibromyxoid sarcoma (LGFMS) is a rare slow-growing malignant tumour with a deceptively benign histologic appearance. It typically involves young or middle-aged adults. These tumours usually occur in the proximal extremities and trunk. Sporadically they may be found in unusual locations leading to diagnostic dilemma. We report a 5year old boy that presented with painless right parotid swelling of 6 weeks duration. There was a 12-week presentation-to-diagnosis delay, due to the initial misdiagnosis as Burkitt's lymphoma that was entertained because of the region involved, rate of progression and endcmicity of Burkitt's in our setting. Compromise of the acrodigcstivc tract was a major challenge, in addition to early recurrence and metastasis. We advocate for high index of suspicion, prompt tissue diagnosis and multidisciplinary intervention for better outcome. [ABSTRACT FROM AUTHOR]

A previously healthy 17-year-old male presented with sudden onset of painful right parotid swelling. It was sudden in onset without any history of trauma. The patient developed deviation of the angle of mouth to the opposite side after 2 days of presentation. A diagnostic aspiration revealed low-flow blood which provided a direction to the final diagnosis of a venous malformation of the right parotid gland. Percutaneous sclerosant embolization with STS under ultrasound guidance was performed and the facial asymmetry with the parotid mass resolved completely within 6 weeks. [ABSTRACT FROM AUTHOR]

Objectives: Sialocele and salivary fistula are not serious but troublesome complications after parotidectomy. Various modalities have been introduced to prevent postoperative saliva‐related complications. However, clinical trials assessing the prophylactic use of botulinum toxin (BTX) for parotidectomy have not been conducted yet. Herein, we report a pilot study investigating the safety and efficacy of intraoperative BTX (iBTX) injection in partial superficial parotidectomy (PSP). Participants: Patients with benign parotid tumour were prospectively recruited for this clinical trial from 2017 to 2019. The study participants underwent PSP with iBTX injection. We retrospectively reviewed the clinical information of all the consecutive patients who underwent PSP without iBTX from 2013 to 2019. These patients were divided into two groups: the iBTX group (n = 36) and the control group (n = 54). Results: Permanent facial palsy was not observed in either group. Two patients (3.7%) had transient marginal palsy in the control group but none had it in the iBTX group. The incidence of sialocele was significantly lower in the iBTX group than in the control group (2.8% vs. 20.4%, P <.05). Although the incidence of salivary fistula was lower in the iBTX group than in the control group (0% vs. 7.4%), no significant difference was determined between the two groups (P =.147). Total drainage volume was significantly lower in the iBTX group than in the control group (55.0 mL vs. 116.6 mL, P <.001). Conclusions: iBTX injection may be safe and effective in reducing sialocele and postoperative drainage in PSP. It might be a useful option to prevent saliva‐related complications after PSP. [ABSTRACT FROM AUTHOR]

The object of this paper was to explore the feasibility and advantages of endoscope-assisted parotid tumour resection. Three databases (PubMed, Web of Science, and Cochrane) were used to search for all related randomised controlled trials or controlled trials (up to November 2019). The key parameters for assessment included 'Endoscope', 'Endoscopes', 'Cancer of Parotid', and 'Parotid Cancer'. To evaluate the feasibility and advantages of endoscope-assisted resection of parotid tumours, the data for each parameter were pooled, based on patients who received endoscope-assisted surgery and those who received conventional surgery. This meta-analysis included seven studies, involving 170 patients in the endoscopy group and 270 patients in the control group. The analysis using the pooled data showed that there were no significant differences in the operating times between the two groups; however, the endoscopy group had significantly shorter incisions and less intraoperative bleeding. In addition, the patients who received endoscope-assisted surgery had lower incidences of temporary facial paralysis and Frey's syndrome after surgery. Patients in the endoscopy group had greater postoperative satisfaction. Endoscope-assisted parotid tumour resection results in only a small, concealed incision wound and fewer postoperative complications. Therefore, it is promising for the surgical treatment of parotid tumours. [ABSTRACT FROM AUTHOR]

Background The facial nerve plays a crucial role in innervating the motor supply of facial muscles, enabling essential facial expressions that facilitate human communication. Defects or damages to this nerve can have significant consequences, leading to functional, emotional, and social difficulties caused by the immobility of facial muscles. Patients suffering from irreversible facial nerve palsy often experience functional symptoms such as eyelid closure defects, mouth deviation, and limited movement. Methods This study aims to address these challenges and offer potential solutions for patients with irreversible facial nerve palsy. In this study, 18 patients (three males and 15 females) underwent temporalis transfer with an intraoral approach in the cranio-orbito-palpebral unity. Preoperative facial reanimation planning involved evaluating the smile's appearance on the unaffected side. Photographs were captured in various positions, and facial expressions were examined. Following this, botulinum toxin was injected into the normal side of the face seven days before the procedure to address the hyperactive condition of the mimic muscles. Results Temporalis transfer with an intraoral approach for oral commissure reanimation in the context of irreversible facial nerve palsy was performed. The surgical procedure combined coronal and orbital approaches and achieved the desired outcomes. Postoperative complications observed included hematomas and ossification. Functional outcomes, assessed using the House-Brackmann grading system, indicated a mean improvement of 2.5, signifying moderate dysfunction with normal tone and facial symmetry. Conclusion This intervention represents an alternative approach to actual techniques of facial palsy reanimation, especially in selected patients who can benefit from the absence of visible scars, such as young patients and those prone to hypertrophic and keloid scarring, as well as patients with non-prominent nasolabial folds., Competing Interests: The authors have declared that no competing interests exist., (Copyright © 2023, Krastinova et al.)

Salivary gland tumor comprises of approximately 3 to 10% of neoplasms of the head and neck region. Parotid gland is the most commonly involved salivary gland with an incidence of 62% followed by submandibular gland and other minor salivary gland tumors. However clinical course of benign and malignant tumors resemble each other in clinical findings, we require histopatholocal or cytological diagnosis for planning of management. To analyze parotid tumors retrospectively with following objectives. (1) Demographic distribution of parotid tumors. (2) To evaluate cytological and histopathological findings of parotid tumors. (3) Correlation of cytological and histopathological findings of parotid tumors. It was a retrospective observational study involving 31 patients who presented with parotid region swelling. Pre operative FNAC (fine needle aspiration cytology) and post operative histopathology were correlated. Surgical management depended on nature of disease. Correlation of FNAC and Histopathology: among 27 cases pre operative FNAC and post operative histopathology was same and in only 3 cases reports differed. One FNAC was inconclusive. In present study, Sensitivity of FNAC is 81.81%, Specificity is 94.73% and accuracy is 90%. FNAC is usually the first investigative modality, as it is a minimally invasive, cheap, OPD procedure that can differentiate benign from malignant tumors. Knowing preoperative pathological nature of disease can help in planning of surgical process. [ABSTRACT FROM AUTHOR]

Most salivary gland tumors arise in the parotid glands, but tumors of the submandibular or other minor salivary glands can also occur. Most tumors are treated with surgery, followed by postoperative radiotherapy when risk of local recurrence is high. Retrospective series suggest the addition of radiotherapy can reduce local recurrence rates from 30 per cent to 10 per cent but there is no effect on overall survival. Radiotherapy treatment can only produce good effects if it is delivered in an appropriate clinical context. Modern radiotherapy planning requires a comprehensive knowledge of cross sectional anatomy and the ability to visualize structures in three dimensions. IMRT is a new technology in radiation oncology that delivers radiation more precisely to the tumor while relatively sparing the surrounding normal tissues.

Highlights • We performed NMR metabolomics analysis of saliva of patients affected by parotid tumor (PT). • We determined the metabolomics profile of saliva of PT patients. • We performed gender based identification of metabolic fingerprints in saliva of PT patients. Abstract Cancers affecting the salivary glands have been an increasing incidence. Salivary gland cancer is not detected until it reaches an advanced stage, which would generally result in a poor prognosis and survival rate. Therefore, early detection as well as the screening of high risk populations with precancerous lesions remains an unmet medical need. In the present work, we present a NMR-based metabolomic study of the saliva of patients suffering from salivary gland tumours. Analysis of data was done using a combined approach based on PRICONA quantitative analysis and statistical multivariate analysis. Interestingly, both the analytical methods indicate that individuals affected by parotid tumour have a characteristic metabolomic profile characterized by abnormalities in the concentration of several aminoacids. Among these the most significant are those relative to Alanine and Leucine suggestive of an alteration in the metabolic pathways of glycogenic aminoacids and ketone bodies. Our data, describing the preliminary metabolomics fingerprint of parotid tumour, are consistent with the recent view that oncogenic signalling corresponds to alteration in the metabolism of nutrient pull (Vander Heiden et al., 2009), rather than to a single metabolite. [ABSTRACT FROM AUTHOR]

Abstract The aims of this study were to evaluate the efficacy of partial parotidectomy using retrograde dissection of the marginal mandibular branch of the facial nerve for benign tumours of the parotid gland and to establish the indications for its use. We examined 106 consecutive patients with previously untreated benign tumours in the lower portion of the parotid gland who were treated by parotidectomy. The first group (anterograde group, n=52) consisted of those who had standard anterograde parotidectomy. The remaining patients, who underwent retrograde parotidectomy, were further divided into two groups: those in whom the upper edge of the tumour was located below the mastoid tip (below mastoid group, n=46) or those in whom it was above the mastoid tip (above mastoid group, n=8). The operating time was significantly shorter in the below mastoid group (141.2, 127.5, and 98.1 minutes, respectively) as was intraoperative blood loss (41.1, 53.0, and 24.4 ml, respectively), compared with the other two groups. There was a higher incidence of facial nerve dysfunction in the above mastoid group postoperatively (4/8) than in the other two groups. The results suggested that the presence of a tumour of any size located below the mastoid tip is a good indication for parotidectomy using retrograde dissection of the marginal mandibular branch of the facial nerve. [ABSTRACT FROM AUTHOR]

Basal cell adenocarcinoma (BCAC) is a rare tumour entity. Despite its tendency to be infiltrative and destructive tumour with propensity to recur, it rarely metastasizes and long-term outcome following surgery is favourable. This paper presents a 42-year-old male with residual BCAC of parotid gland that had extended into infratemporal fossa and intracranial. The important aspect of this case is the rarity occurrence of BCAC of parotid with intracranial extension and its surgical approaches to achieve tumour clearance. [ABSTRACT FROM AUTHOR]

Lipoblastomas arising within the parotid gland and extending into the infratemporal fossa are very rare. They are common in children

Lipoblastomas arising within the parotid gland and extending into the infratemporal fossa are very rare. They are common in children < 3 years of age. Access to the tumour requires careful planning and interpretation of imaging studies. Lipoblastomas tend to recur. Meticulous dissection of the tumour is needed to prevent recurrence. By adopting the appropriate approach, complete removal is possible with minimal morbidity.

Objectives We determined the correlation between saliva and serum for CA125 and leptin, and evaluated their clinical screening potential for parotid tumours. Subjects and Methods Serum, acid-stimulated bilateral parotid saliva and chewing-stimulated whole saliva were collected and measured the levels of CA125 and leptin with electrochemiluminescence immunoassay and enzyme-linked immunosorbent assay for healthy controls and patients with unilateral parotid tumour. Intra- and intergroup comparisons were made among them. Correlations and receiver operating curve analyses were also conducted. Results There was no correlation between salivary and serum CA125 ( r = −0.157-0.265, P > 0.05), while significant correlation was found for leptin ( r = 0.219-0.761, P < 0.05). Leptin levels in tumour parotid saliva and CA125 levels in whole saliva were elevated significantly ( P < 0.001) and showed screening potential for parotid tumours. Salivary and serum leptin levels were significantly higher in women than in men ( P < 0.001). Conclusions Salivary CA125 might originate primarily from salivary gland and tumour rather than from blood, while salivary leptin might originate from both blood and salivary gland. Multiple sources might contribute to the significantly elevated CA125 in whole saliva. Whole saliva CA125 and parotid saliva leptin reflected the occurrence of parotid tumours, while serum CA125 and leptin did not. Salivary CA125 and leptin could not distinguish malignant parotid tumours. When detecting leptin level, the influence of subjects' sex must be considered. [ABSTRACT FROM AUTHOR]

Neurogenic neoplasms presenting as parotid gland tumors are extremely uncommon. We present the case of a solitary neurofibroma of the facial nerve within the parotid gland occurring in a 36-year-old male who presented with a painless enlargement in the right-side region of the parotid gland over a period of 1 year with normal facial nerve function. Magnetic resonance imaging revealed a well-demarcated round mass within the right parotid. At surgery, a tumor was found involving the main trunk of the facial nerve, histopathologically representing a neurofibroma. [ABSTRACT FROM AUTHOR]

Objective The pathology of the salivary glands focuses on that of the parotid gland. The purpose of this study is to clarify and explain the epidemiological features of parotid tumors in a Senegalese context, to highlight the importance of clinical examination when access to complementary investigations is limited, to discuss respective indications and finally to describe certain aspects of treatment in our context. Materials and methods This retrospective study of 114 cases of parotidectomy spans 16 years, from 1992 to 2007. It was performed in the ENT department of University Hospital of Fann, Senegal. All patients operated on for chronic mass of the parotid region for whom histological results were available when initially included. Benign swellings were subsequently excluded. The study parameters were epidemiological, clinical, paraclinical and surgical. Results The 114 parotidectomies showed a predominance of benign tumours: 63 procedures (55.26%) essentially concerned pleomorphic adenoma; 30 cases (26.31%) concerned malignant tumours, mainly parotid adenocarcinoma. There were 21 cases of benign swelling (18.4%). The study focused on the series of 93 cases of benign and malignant tumours of the parotid gland. Both sexes were affected similarly. All age groups were concerned, from 5 to 89 years. A total of 97% of patients underwent surgery: conservative total parotidectomy in 75.51% of cases. Conclusion Although there are features specific to the local context, the epidemiological profile of parotid tumours is well-known. Indications for complementary investigations are discussed, as availability in Senegal is restricted, highlighting the important role of clinical examination in the management of parotid tumours. [ABSTRACT FROM AUTHOR]

Abstract: Radical treatment of parotid neoplasms may lead to complex parotid defects that present functional and aesthetic reconstructive challenges. We report our experience using the lateral thoracic wall as a single donor site. Between 2003 and 2009, four patients with malignant tumours in the parotid gland underwent radical parotidectomy and simultaneous reconstruction using a perforator latissimus dorsi cutaneous free flap (de-epithelialized and entire skin paddle in two cases each). A thoracodorsal nerve graft was used in all cases to replace the intraglandular branches of the facial nerve. Costal grafts were used for mandibular reconstruction in two patients. All patients underwent postoperative physiotherapy. No donor-site complication occurred and all treatments achieved good aesthetic results. All patients recovered nearly complete symmetry at rest and partial facial mimetic function. The lateral thoracic wall is a good donor site for the reconstruction of complex parotid defects. [Copyright &y& Elsevier]

Summary: Introduction: The role of fine-needle aspiration cytology (FNAC) in the management of parotid tumours is still the subject of controversy. The purpose of this study was to determine the diagnostic value of FNAC in our institution in order to define its place in the diagnostic strategy. Patients and methods: This retrospective study was based on 249 patients who had undergone preoperative FNAC before being operated in our institution between 2001 and 2008. All examinations were performed and interpreted by the same experienced pathologist. Results: Among the 249 patients included in this study, 187 (75%) had a benign tumour and 62 (25%) had a malignant tumour. No complications of FNAC were observed. Cytological findings were non-contributory in 47 patients (18%). The sensitivity of FNAC for the diagnosis of malignancy was 80% with a specificity of 89.5%. Among the 11 false-negative results, lymphomas and low-grade mucoepidermoid carcinomas were the most common histological types. Among the 16 false-positive results, Warthin''s tumours, pleomorphic adenomas and lymphoepithelial lesions were the most common histological types. Accurate histological classification of the tumour was reported in 79.5% of cases (86% for benign tumours and 44% for malignant tumours). Conclusion: FNAC is a reliable examination providing important information to the surgeon in the preoperative diagnostic assessment. [Copyright &y& Elsevier]

Abstract: Introduction: Pilomatricomas greater than 5cm in dimension (i.e. “giant” pilomatricomas) are uncommon, especially in the cheek. A brief review of the literature is presented. Case report: We report a rare case of a giant pilomatricoma of the right cheek immediately overlying and involving the lateral lobe of the parotid gland. The tumour was removed with preservation of the facial nerve. A cervicofacial fasciocutaneous advancement flap was used to reconstruct the surgical defect. Conclusion: Pilomatricoma should be considered in the differential diagnosis of large cheek tumours. Giant pilomatricomas involving the parotid gland can be excised without sacrificing the facial nerve and the resultant surgical defect reconstructed with excellent cosmesis in a single-stage procedure. [Copyright &y& Elsevier]

Objective: This is a case report to discuss regarding the rarity of lipoma arising from parotid gland. We are also highlighting the importance of imaging as diagnostic tool and surgical management in our centre. Design: Retrospective case note analysis and follow up of the case. Materials and Methods: Review of the patient's case note, follow up photos and investigation result was made. Results: A patient presented with 3 years history of slow progressive painless right parotid gland swelling measuring 3.0 cm X 3.0 cm, which clinically suggestive of a benign lesion likely a Warthin's tumour. The lesion was surgically excised and noted to be clinically intraparotid lipomatous lesion. Histopathology study revealed it to be a lipoma. Conclusion: Intraparotid lipoma is a rare benign parotid tumour which is best to diagnose retrospectively before proper surgical management is planned. Clinical diagnostic approach alone might not be sufficient while FNAC was noticeably less accurate. Advanced diagnostic imaging has the potential to play a key role in obtaining accurate pre operative diagnosis. Surgical approaches open to superficial parotidectomy or extracapsular dissection (enucleation) depending on tumour size, tumour location and its relation to parotid gland to achieve complete tumour resection and facial nerve preservation. The incidence of tumour recurrence is rare. [ABSTRACT FROM AUTHOR]

Background: The role of fine-needle aspiration (FNA) in salivary gland lesions as a preoperative diagnosis has always been under scrutiny. Several studies have shown that frozen section (FS) is accurate for pathological diagnosis and decision-making during the surgery. This study has been carried out to assess the accuracy of FNA and FS in parotid surgeries. Methods: All parotid lesions removed between July 1998 and June 2003 by the Department of Otolaryngology, Head and Neck unit at Monash Medical Centre were reviewed. FNA, FS and definitive pathology were collected and discrepancies were identified. Results: Eighty-five parotid tumours had been removed. Thirty-three were malignant in which squamous cell carcinoma was the most common. FS was able to differentiate benign tumours from malignant with 100% accuracy (30 cases). FS was able to alter the surgical decisions in six cases. FNA had been carried out in 62 cases, with sensitivity and specificity of 77.2 and 90%, respectively. Conclusion: Frozen section in parotid surgery is accurate, inexpensive and may add important information that alters management and improves the outcome. The use of FS routinely in parotid surgery is recommended. [ABSTRACT FROM AUTHOR]

Background: Most of the recent reports on the surgical management of parotid gland disorders come from specialist divisions of otolaryngology, head and neck, or faciomaxillary surgery. The aim of the present study was to evaluate the outcome of surgery for parotid tumours in a general surgical unit of a teaching hospital. Method: A prospective clinicopathological study was undertaken over a 5-year period for consecutive patients operated on for parotid gland tumours in the King Saud University Unit of Riyadh Medical Complex. Parameters analyzed were demographic details, clinical presentation, diagnostic work-up, type of surgery, and outcome in terms of early and late morbidity. Results: Thirty seven parotid operations were performed on 36 consecutive patients. All patients presented with parotid gland swelling. Mean age was 51.6 years with a male preponderance. Fine-needle aspiration diagnosed the pathology in 33 out of 37 lesions. Pleomorphic adenoma was the commonest pathology observed in 24 patients (64.9%). Warthin's tumour was more common among male patients and was the only pathology with bilateral involvement. Malignant tumour was found in five patients (13.5%). Superficial conservative parotidectomy was the most frequently performed operation (84%). Overall postoperative morbidity was 13.5%. Transient facial nerve palsy was observed in seven cases (19%). There was no recurrence identified in patients with benign diseases during the mean follow up of 38.5 months. Conclusion: Parotid gland surgery can still be performed in a general surgery unit with comparable outcome. However, the operation should be performed in units with special interest and experience in surgery for parotid gland disorders. [ABSTRACT FROM AUTHOR]

Objectives: There is a diversity of opinion regarding the role offine needle aspiration cytology (FNAC) in the pre-operative evaluationof the parotid mass. This study further investigates the role of FNACfrom the standpoint of the clinician attempting to resolve one or moreclinical issues. Methods: A retrospective study conducted at two UKHospitals with no overlap of cytopathologists or surgeons. Patientsundergoing parotidectomy at each institution were identified fromPathology department databases. The definitive histopathologicaldiagnosis was compared with any preoperative FNAC diagnosis. Cytologyresults were classified as suggestive, non-diagnostic, sampling error,or misleading. Setting: The study was conducted in a District GeneralHospital and a University Teaching Hospital providing secondary care foreach community. Results: For the University Teaching Hospital thesensitivity in distinguishing malignant from benign disease was 79% (95%CI 61-97%) with a specificity 84% (95% CI 73-95%). However, three ofeight patients with a primary parotid salivary gland malignancy werereported as having benign disease on FNAC. For the participatingDistrict General Hospital the sensitivity in distinguishing malignantfrom benign disease was 38% (95% CI 13-63%) and specificity 95% (95% CI73-95%). Conclusions: Fine needle aspiration cytology does not reliablydistinguish a benign from a malignant primary salivary gland neoplasm inthe participating institutions. Where clinical teams use FNAC in anattempt to resolve this clinical problem, the results should beinterpreted with caution and an ongoing audit of performance is required [ABSTRACT FROM AUTHOR]

Background: The aim of this study was to evaluate the accuracy of fine-needle aspiration cytology in the diagnosis of parotid tumours. Methods: A retrospective review was conducted to examine the preoperative cytological and final histological results of patients who underwent parotidectomies at our institution. Results: Sensitivity and specificity for diagnosing malignant and benign tumours were 80%, 100%, and 98.5%, 87.5%, respectively, and 85.1% of benign tumours were accurately typed on fine-needle aspiration cytology compared with only 40% in the malignant group. Using the clinical parameters of associated facial nerve palsy or presence of cervical lymphadenopathy to indicate the presence of malignancy, the diagnostic yield was only 30%. Conclusion: Fine-needle aspiration cytology is useful in the preoperative assessment of parotid tumours as it is more reliable than clinical examination to diagnose malignant parotid tumours. Although it may not accurately type the malignant tumours, the diagnosis of malignant tumours preoperatively may allow for appropriate surgical planning by the surgeon. [ABSTRACT FROM AUTHOR]

Breast cancer presenting as parotid tumour is very rare. This is the first reported case in which parotid tumour was the presenting complaint of the patient. Since the patient was estrogen and progesterone receptor positive - was put on hormone therapy and responded well. [ABSTRACT FROM AUTHOR]

We report a case of a 59-year-old man who presented with a preauricular facial lump that was suspected to be a parotid malignancy based on fine needle aspiration. A chest radiograph and a computed tomogram showed a mass in the lungs and several metastases, and caused a diagnostic dilemma as to the origin of the parotid mass, which was later confirmed to be metastatic disease that had arisen from a carcinoma of unknown origin. Infraclavicular metastasis to the parotid is rare but should not be overlooked particularly in patients who present with coexisting conditions, or when cytological findings are atypical. [ABSTRACT FROM AUTHOR]

Objectives: To explore the utility of diffusion tensor imaging (DTI) and acoustic radiation force impulse (ARFI) imaging in the diagnosis of parotid tumours., Methods: 51 patients with parotid tumours were examined with DTI on 3.0-T MRI and ARFI imaging on an ultrasound scanner before surgery. Values of apparent diffusion coefficient (ADC), fractional anisotropy (FA) and shear-wave velocity (SWV) were calculated and analyzed with independent samples Wilcoxon-Mann-Whitney test. Cut-off values, sensitivity and specificity were calculated with receiver-operating characteristic (ROC) curve analysis. The value of combination was calculated through parallel test for the cut-off value of ADC, FA and SWV (combination = 0 or 1); then, ROC analysis was performed with pathological results as the gold standard to calculate the sensitivity and specificity for the combination of the three parameters distinguishing benign and malignant parotid tumours. Pathological diagnosis for every patient was made post-operatively from the tumour tissue taken during operation., Results: There was a significant difference between benign and malignant tumours in the values of ADC, FA and SWV (p = 0.032, p = 0.011 and p < 0.0001); a significant difference in the values was also found between pleomorphic adenoma and malignant tumour (p = 0.0012, p < 0.0001 and p = 0.0002). The diagnosis cut-off points between benign and malignant tumours for ADC, FA and SWV were 1.02 × 10(-3) mm(2) s(-1), 0.24 and 2.76 m s(-1), respectively; the sensitivity for ADC, FA and SWV was 87.50, 62.50 and 68.75%; the specificity was 45.71, 82.86 and 97.14%. Analysis of the combination of the three parameters increased the sensitivity, specificity, Youden index and area under the ROC curve compared with analysis of each parameter alone for distinguishing benign and malignant tumours., Conclusions: The diagnostic value of the combination of the three parameters for distinguishing benign and malignant parotid tumours is the best; SWV is the preferred indicator. Parameters of DTI and ARFI may reflect the histological characteristics of parotid tumours and predict benignancy and malignancy and could provide quantitative information about the tumour. Combination of DTI with ARFI imaging had obvious advantage for the diagnosis of parotid tumours than each alone.

The article presents a case study in which a scratch by a cat led to the growth of a malignant tumor in the right parotid region of a 14-year old girl. She had been suffering from swelling for three weeks without overt symptoms. A recognized cause of lymphademtisisc is the cat scratch disease. Parotid gland excision biopsy is suggested as an effective method of treatment.

Sixty five patients who had undergone surgery for parotid tumours over a period of nine years were studied retrospectively. There were 45 males and 20 females. There were 49 benign and 16 malignant tumours. Age ranged 35-69 years; mean 47 years. Pain (6%) and facial palsy (3%) were unusual features. Size of tumour at presentation varied from 1.5 to 12 cm. Superficial parotidectomy was the commonest operation performed and Total/Radical/Extended parotidectomy was done in selected cases. Postoperative radiotherapy was used in six cases. No recurrences were noted following surgery for benign tumours. However a local recurrence rate of 37% was found for malignancies (6/16 cases). This paper aims to review the experience of managing these tumours in the setting of service hospitals.