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Start Over Author "Pagano N" Publication Type Academic Journals
286 results on '"Pagano N"'

17. Endorectal endoscopic ultrasound for the locoregional staging of rectal mucosal lesions: retrospective multicenter analysis.

Author

Mauriello, A., Fimiano, F., Degan, M., Borsato, A., Caneglias, A., Staiano, M. T., Dall'Amico, E., Pagano, N., Sacco, M., and De Angelis, C.

Subjects
ENDOSCOPIC ultrasonography, ENDORECTAL ultrasonography, RETROSPECTIVE studies, MAGNETIC resonance imaging, RECTAL cancer, SURGICAL pathology
Abstract

This article, published in the journal Endoscopy, discusses the role of transrectal endoscopic ultrasound (TREUS) in the locoregional staging of rectal mucosal lesions (mRL). The study, conducted at two medical centers in Italy, aimed to determine the ability of TREUS to differentiate early stages (T0-T1) from advanced stages (T2-T3) of colorectal cancer (CRC). The results showed that TREUS is a reliable method for staging early mRL, allowing for the selection of appropriate treatment options. The diagnostic accuracy of TREUS was found to be 89.6%, with some cases being both over-staged and under-staged. The study suggests that TREUS can be beneficial in guiding effective and minimally invasive local treatments for early stages of CRC. [Extracted from the article]

Published
2024
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26. Endoscopic submucosal dissection for superficial premalignant and malignant epithelial neoplasms of the digestive tract: a real-life experience in Italy.

Author

PAGANO, N., FRAZZONI, L., LA PORTA, M., FUCCIO, L., BAZZOLI, F., and ZAGARI, R. M.

Abstract

OBJECTIVE: Endoscopic submucosal dissection (ESD) is a technique for en bloc resection of neoplastic lesions of the digestive tract. Endoscopic submucosal dissection was developed in Asia, and data from Western countries are scarce. Our study aimed to assess the efficacy and safety of ESD for resection of superficial premalignant and malignant epithelial neoplasms in a tertiary center in Italy. PATIENTS AND METHODS: All patients with gastrointestinal lesions who underwent ESD between January 2013 and December 2018 in our center were retrospectively evaluated. Technical success, en bloc, R0, curative resection, and complication rates were assessed. RESULTS: A total of 107 lesions (stomach, no.=41; rectum, no.=32; colon, no.=28; esophagus, no.=5; duodenum, no.=1) were resected by ESD in 93 patients. Endoscopic submucosal dissection was technically successful in 99.1% (106/107) of lesions. Among the 90 superficial premalignant and malignant epithelial neoplasms, en bloc, and R0 resection rates were 97.8% (no.=88) and 75.6% (no.=68), respectively. Major complications occurred in 9.3% (10/107) of cases: 4 (3.7%) were perforations and 6 (5.6%) were major bleedings. All complications, but two which needed surgery, were managed endoscopically. CONCLUSIONS: Our study shows that ESD is a feasible, effective, and safe technique in a Western country. [ABSTRACT FROM AUTHOR]

Published
2019

44. Balanced Propofol Sedation in Patients Undergoing EUS-FNA: A Pilot Study to Assess Feasibility and Safety.

Author

Pagano, N., Arosio, M., Romeo, F., Rando, G., Del Conte, G., Carlino, A., Strangio, G., Vitetta, E., Malesci, A., and Repici, A.

Subjects
*ENDOSCOPIC surgery, *ENDOSCOPIC ultrasonography, *ASPIRATORS, *DIAGNOSTIC ultrasonic imaging, *FEASIBILITY studies, *MIDAZOLAM
Abstract

Introduction and aims. Balanced propofol sedation (BPS) administered by gastroenterologists has gained popularity in endoscopic procedures. Few studies exist about the safety of this approach during endosonography with fine needle aspiration (EUS-FNA). We assessed the safety of BPS in EUS-FNA. Materials and methods. 112 consecutive patients, referred to our unit to perform EUSFNA, from February 2008 to December 2009, were sedated with BPS. A second gastroenterologist administered the drugs and monitorized the patient. Results. All the 112 patients (62 males, mean age 58.35) completed the examination. The mean dose of midazolam and propofol was, respectively, of 2.1 mg (range 1-4mg) and 350 mg (range 180-400). All patients received oxygen with amean flux of 4 liter/minute (range 2-6 liters/minute). Themean recovery time after procedure was 25minutes (range 18-45 minutes). No major complications related to sedation were registered during all procedures. The oxygen saturation of all patients never reduced to less than 85%. Blood systolic pressure during and after the procedure never reduced to less than 100mmHg. Conclusions. In our experience BPS administered by non-anaesthesiologists provided safe and successful sedation in patients undergoing EUS-FNA. [ABSTRACT FROM AUTHOR]

Published
2011
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