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This study aimed to automatically classify physical fitness and cardiometabolic risk in a Chilean adolescent using self-organizing maps. This cross-sectional study analysed a nationally representative database from the Physical Education Quality Measurement System (n = 7197). Physical fitness and cardiometabolic risk variables were derived from anthropometric indicators. Self-Organizing maps (SOM) were employed to identify participant profiles based on an unsupervised predictive model. After implementing and training the SOM, a detailed analysis of the generated maps was conducted to interpret the revealed relationships and clusters. The analysis resulted in three classification groups, categorizing the sample into low, moderate, and high-risk levels. Students with better physical fitness exhibited lower cardiometabolic risk levels and a lower body mass index. SOM, through an unsupervised model, is a reliable tool for classifying cardiometabolic risk and physical fitness in adolescents. [ABSTRACT FROM AUTHOR]

In the complex and dynamic landscape of cyber threats, organizations require sophisticated strategies for managing Cybersecurity Operations Centers and deploying Security Information and Event Management systems. Our study enhances these strategies by integrating the precision of well-known biomimetic optimization algorithms—namely Particle Swarm Optimization, the Bat Algorithm, the Gray Wolf Optimizer, and the Orca Predator Algorithm—with the adaptability of Deep Q-Learning, a reinforcement learning technique that leverages deep neural networks to teach algorithms optimal actions through trial and error in complex environments. This hybrid methodology targets the efficient allocation and deployment of network intrusion detection sensors while balancing cost-effectiveness with essential network security imperatives. Comprehensive computational tests show that versions enhanced with Deep Q-Learning significantly outperform their native counterparts, especially in complex infrastructures. These results highlight the efficacy of integrating metaheuristics with reinforcement learning to tackle complex optimization challenges, underscoring Deep Q-Learning's potential to boost cybersecurity measures in rapidly evolving threat environments. [ABSTRACT FROM AUTHOR]

One of the significant challenges in scaling agile software development is organizing software development teams to ensure effective communication among members while equipping them with the capabilities to deliver business value independently. A formal approach to address this challenge involves modeling it as an optimization problem: given a professional staff, how can they be organized to optimize the number of communication channels, considering both intra-team and inter-team channels? In this article, we propose applying a set of bio-inspired algorithms to solve this problem. We introduce an enhancement that incorporates ensemble learning into the resolution process to achieve nearly optimal results. Ensemble learning integrates multiple machine-learning strategies with diverse characteristics to boost optimizer performance. Furthermore, the studied metaheuristics offer an excellent opportunity to explore their linear convergence, contingent on the exploration and exploitation phases. The results produce more precise definitions for team sizes, aligning with industry standards. Our approach demonstrates superior performance compared to the traditional versions of these algorithms. [ABSTRACT FROM AUTHOR]

Stagnation at local optima represents a significant challenge in bio-inspired optimization algorithms, often leading to suboptimal solutions. This paper addresses this issue by proposing a hybrid model that combines the Orca predator algorithm with deep Q-learning. The Orca predator algorithm is an optimization technique that mimics the hunting behavior of orcas. It solves complex optimization problems by exploring and exploiting search spaces efficiently. Deep Q-learning is a reinforcement learning technique that combines Q-learning with deep neural networks. This integration aims to turn the stagnation problem into an opportunity for more focused and effective exploitation, enhancing the optimization technique's performance and accuracy. The proposed hybrid model leverages the biomimetic strengths of the Orca predator algorithm to identify promising regions nearby in the search space, complemented by the fine-tuning capabilities of deep Q-learning to navigate these areas precisely. The practical application of this approach is evaluated using the high-dimensional Heartbeat Categorization Dataset, focusing on the feature selection problem. This dataset, comprising complex electrocardiogram signals, provided a robust platform for testing the feature selection capabilities of our hybrid model. Our experimental results are encouraging, showcasing the hybrid strategy's capability to identify relevant features without significantly compromising the performance metrics of machine learning models. This analysis was performed by comparing the improved method of the Orca predator algorithm against its native version and a set of state-of-the-art algorithms. [ABSTRACT FROM AUTHOR]

In the optimization field, the ability to efficiently tackle complex and high-dimensional problems remains a persistent challenge. Metaheuristic algorithms, with a particular emphasis on their autonomous variants, are emerging as promising tools to overcome this challenge. The term "autonomous" refers to these variants' ability to dynamically adjust certain parameters based on their own outcomes, without external intervention. The objective is to leverage the advantages and characteristics of an unsupervised machine learning clustering technique to configure the population parameter with autonomous behavior, and emphasize how we incorporate the characteristics of search space clustering to enhance the intensification and diversification of the metaheuristic. This allows dynamic adjustments based on its own outcomes, whether by increasing or decreasing the population in response to the need for diversification or intensification of solutions. In this manner, it aims to imbue the metaheuristic with features for a broader search of solutions that can yield superior results. This study provides an in-depth examination of autonomous metaheuristic algorithms, including Autonomous Particle Swarm Optimization, Autonomous Cuckoo Search Algorithm, and Autonomous Bat Algorithm. We submit these algorithms to a thorough evaluation against their original counterparts using high-density functions from the well-known CEC LSGO benchmark suite. Quantitative results revealed performance enhancements in the autonomous versions, with Autonomous Particle Swarm Optimization consistently outperforming its peers in achieving optimal minimum values. Autonomous Cuckoo Search Algorithm and Autonomous Bat Algorithm also demonstrated noteworthy advancements over their traditional counterparts. A salient feature of these algorithms is the continuous nature of their population, which significantly bolsters their capability to navigate complex and high-dimensional search spaces. However, like all methodologies, there were challenges in ensuring consistent performance across all test scenarios. The intrinsic adaptability and autonomous decision making embedded within these algorithms herald a new era of optimization tools suited for complex real-world challenges. In sum, this research accentuates the potential of autonomous metaheuristics in the optimization arena, laying the groundwork for their expanded application across diverse challenges and domains. We recommend further explorations and adaptations of these autonomous algorithms to fully harness their potential. [ABSTRACT FROM AUTHOR]

This paper presents a set of adaptive parameter control methods through reinforcement learning for the particle swarm algorithm. The aim is to adjust the algorithm's parameters during the run, to provide the metaheuristics with the ability to learn and adapt dynamically to the problem and its context. The proposal integrates Q–Learning into the optimization algorithm for parameter control. The applied strategies include a shared Q–table, separate tables per parameter, and flexible state representation. The study was evaluated through various instances of the multidimensional knapsack problem belonging to the NP -hard class. It can be formulated as a mathematical combinatorial problem involving a set of items with multiple attributes or dimensions, aiming to maximize the total value or utility while respecting constraints on the total capacity or available resources. Experimental and statistical tests were carried out to compare the results obtained by each of these hybridizations, concluding that they can significantly improve the quality of the solutions found compared to the native version of the algorithm. [ABSTRACT FROM AUTHOR]

The Thebes Limestone Formation of Lower Eocene age is one of the most extensive rock units in Egypt. It is of importance to the apogee of the ancient Egyptian civilization, particularly in Luxor (South-Central Egypt), where the rock formation hosts the Theban Necropolis, a group of funerary chambers and temples from the New Kingdom Egyptian era (3500–3000 BP). In this work, we investigated the petrophysical and rock mechanical properties (e.g., rock strength, critical crack stress thresholds) through laboratory tests on eleven rock blocks collected from one area within the Theban Necropolis known as the Valley of the Kings (KV). The blocks belong to Member I of the Thebes Limestone Formation, including six blocks of marly limestone, three blocks of micritic limestone, one block of argillaceous limestone from the Upper Esna Shale Formation, and one block of silicified limestone of unknown origin. Special attention was given to the orientation of bedding planes in the samples: tests were conducted in parallel (PA) and perpendicular (PE) configurations with respect to bedding planes. We found that the marly limestone had an average unconfined compressive strength (UCS) of 30 MPa and 39 MPa for the PA and PE tests, respectively. Similarly, the micritic limestone tests showed an average UCS of 24 MPa for the PA orientation and 58 MPa for the PE orientation. The critical crack thresholds were the first ever reported for Member I, as measured with strain gauge readings. The average crack initiation (CI) stress thresholds for the marly limestone (PA: 14 MPa) and the micritic limestone (PA: 11 MPa; PE: 24 MPa) fall within the typical ratio of CI to UCS (0.36–0.52). The micritic limestone had an average Young's modulus (E) of 19.5 GPa and 10.3 GPa for PA and PE, respectively. The Poisson's ratios were 0.2 for PA and 0.1 for PE on average. Both marly and micritic limestone can be characterised by a transverse isotropic strength behaviour with respect to bedding planes. The failure strength for intact anisotropic rocks depends on the orientation of the applied force, which must be considered when assessing the stability of tombs and cliffs in the KV and will be used to understand and improve the preservation of this UNESCO World Heritage site. [ABSTRACT FROM AUTHOR]

Nature–inspired computing is a promising field of artificial intelligence. This area is mainly devoted to designing computational models based on natural phenomena to address complex problems. Nature provides a rich source of inspiration for designing smart procedures capable of becoming powerful algorithms. Many of these procedures have been successfully developed to treat optimization problems, with impressive results. Nonetheless, for these algorithms to reach their maximum performance, a proper balance between the intensification and the diversification phases is required. The intensification generates a local solution around the best solution by exploiting a promising region. Diversification is responsible for finding new solutions when the main procedure is trapped in a local region. This procedure is usually carryout by non-deterministic fundamentals that do not necessarily provide the expected results. Here, we encounter the stagnation problem, which describes a scenario where the search for the optimum solution stalls before discovering a globally optimal solution. In this work, we propose an efficient technique for detecting and leaving local optimum regions based on Shannon entropy. This component can measure the uncertainty level of the observations taken from random variables. We employ this principle on three well–known population–based bio–inspired optimization algorithms: particle swarm optimization, bat optimization, and black hole algorithm. The proposal's performance is evidenced by solving twenty of the most challenging instances of the multidimensional knapsack problem. Computational results show that the proposed exploration approach is a legitimate alternative to manage the diversification of solutions since the improved techniques can generate a better distribution of the optimal values found. The best results are with the bat method, where in all instances, the enhanced solver with the Shannon exploration strategy works better than its native version. For the other two bio-inspired algorithms, the proposal operates significantly better in over 70% of instances. [ABSTRACT FROM AUTHOR]

Osteoporosis is still a worldwide problem, particularly due to associated fragility fractures. Patients at risk of fracture are currently detected using the X-Ray gold standard dual-energy X-ray absorptiometry (DXA), based on a calibrated 2-D image. Different alternatives, such as 3-D X-rays, magnetic resonance imaging (MRI) or ultrasound, have been proposed, the latter having advantages of being portable and sensitive to mechanical and geometrical properties. Bidirectional axial transmission (BDAT) has been used to classify between patients with or without nontraumatic fractures using “classical” ultrasonic parameters, such as velocities, as well as cortical thickness and porosity, obtained from an inverse problems. Recently, complementary parameters acquired with structural and textural analysis of guided wave spectrum images (GWSIs) have been introduced. These parameters are not limited by solution ambiguities, as for inverse problem. The aim of the study is to improve the patient classification using a feature selection strategy for all available ultrasound features completed by clinical parameters. To this end, three classical feature ranking methods were considered: analysis of variance (ANOVA), recursive feature elimination (RFE), and extreme gradient boosting importance feature (XGBI). In order to evaluate the performance of the feature selection techniques, three classical classification methods were used: logistic regression (LR), support vector machine (SVM), and extreme gradient boosting (XGB). The database was obtained from a previous clinical study [Minonzio et al., 2019]. Results indicate that the best accuracy of 71 [66–76]% was achieved by using RFE and SVM with 22 (out of 43) ultrasonic and clinical features. This value outperformed the accuracy of 68 [64–73]% reached with 2 (out of 6) DXA and clinical features. These values open promising perspectives toward improved and generalizable classification of patients at risk of fracture. [ABSTRACT FROM AUTHOR]

An influence game is a simple game represented over an influence graph (i.e., a labeled, weighted graph) on which the influence spread phenomenon is exerted. Influence games allow applying different properties and parameters coming from cooperative game theory to the contexts of social network analysis, decision-systems, voting systems, and collective behavior. The exact calculation of several of these properties and parameters is computationally hard, even for a small number of players. Two examples of these parameters are the length and the width of a game. The length of a game is the size of its smaller winning coalition, while the width of a game is the size of its larger losing coalition. Both parameters are relevant to know the levels of difficulty in reaching agreements in collective decision-making systems. Despite the above, new bio-inspired metaheuristic algorithms have recently been developed to solve the NP-hard influence maximization problem in an efficient and approximate way, being able to find small winning coalitions that maximize the influence spread within an influence graph. In this article, we apply some variations of this solution to find extreme winning and losing coalitions, and thus efficient approximate solutions for the length and the width of influence games. As a case study, we consider two real social networks, one formed by the 58 members of the European Union Council under nice voting rules, and the other formed by the 705 members of the European Parliament, connected by political affinity. Results are promising and show that it is feasible to generate approximate solutions for the length and width parameters of influence games, in reduced solving time. [ABSTRACT FROM AUTHOR]

Human behavior is manly addressed by emotions. One of the most accepted models that represent emotions is known as the circumplex model. This model organizes emotions into points on a bidimensional plane: valence and arousal. Despite the importance of the emotion recognition, there are limited initiatives that seek to classify emotions easily in an uncontrolled environment. In this work, we present the architecture and the design of an extensible software which allows recognizing and classifying emotions by using a low-cost EEG. The proposed software implements an emotion classifier although a support vector machines (SVM) are boosted with an autonomous bio-inspired approach. The contribution was experimentally evaluated by taking a set of well-known validated EEG Databases for Emotion Recognition. Computational experiments show promising results. Using our proposal for EEG emotion classification, we reach an accuracy close to 95%. The results obtained confirm that our approach is able to overcome to a commonly used SVM classifier and that the proposed software can be useful in real environments. [ABSTRACT FROM AUTHOR]

During the last years, highly-recognized computational intelligence techniques have been proposed to treat classification problems. These automatic learning approaches lead to the most recent researches because they exhibit outstanding results. Nevertheless, to achieve this performance, artificial learning methods firstly require fine tuning of their parameters and then they need to work with the best-generated model. This process usually needs an expert user for supervising the algorithm's performance. In this paper, we propose an optimized Extreme Learning Machine by using the Bat Algorithm, which boosts the training phase of the machine learning method to increase the accuracy, and decreasing or keeping the loss in the learning phase. To evaluate our proposal, we use the Parkinson's Disease audio dataset taken from UCI Machine Learning Repository. Parkinson's disease is a neurodegenerative disorder that affects over 10 million people. Although its diagnosis is through motor symptoms, it is possible to evidence the disorder through variations in the speech using machine learning techniques. Results suggest that using the bio-inspired optimization algorithm for adjusting the parameters of the Extreme Learning Machine is a real alternative for improving its performance. During the validation phase, the classification process for Parkinson's Disease achieves a maximum accuracy of 96.74% and a minimum loss of 3.27%. [ABSTRACT FROM AUTHOR]

Brain network analysis using functional magnetic resonance imaging (fMRI) is a widely used technique. The first step of brain network analysis in fMRI is to detect regions of interest (ROIs). The signals from these ROIs are then used to evaluate neural networks and quantify neuronal dynamics. The two main methods to identify ROIs are based on brain atlas registration and clustering. This work proposes a bioinspired method that combines both paradigms. The method, dubbed HAnt, consists of an anatomical clustering of the signal followed by an ant clustering step. The method is evaluated empirically in both in silico and in vivo experiments. The results show a significantly better performance of the proposed approach compared to other brain parcellations obtained using purely clustering-based strategies or atlas-based parcellations. [ABSTRACT FROM AUTHOR]

This investigation intends to describe some of the influences that revolutionary notions had on the Catholic Church, as can observed in the analysis of the pastoral letters of the Bishop's Conference between 1960 and 1975. In order to do this, we have elaborated a theoretical framework that allows the portrayal of the concept of revolution through the thought of José de Ortega y Gasset, and of other authors that complement his views. Then we apply it to the Chilean situation in the second half of the 20th century. It was during this period that there came to power a government that had a program which, in essence, contained all those elements which, according to our framework, can be called revolutionary. It was also accompanied by political parties which, in their conventions proposed great institutional, economic and social transformation. Finally, we analyze the changes experienced by the Catholic Church during the 1960's, as it is expressed in pastoral letters, in order to point out the manner in which revolutionary thought and action influenced its pronouncements on the country's socio-political reality and also of its own structure. [ABSTRACT FROM AUTHOR]

Metaheuristics are multi-purpose problem solvers devoted to particularly tackle large instances of complex optimization problems. However, in spite of the relevance of metaheuristics in the optimization world, their proper design and implementation to reach optimal solutions is not a simple task. Metaheuristics require an initial parameter configuration, which is dramatically relevant for the efficient exploration and exploitation of the search space, and therefore to the effective finding of high-quality solutions. In this paper, the authors propose a variation of the water cycle inspired metaheuristic capable of automatically adjusting its parameter by using the autonomous search paradigm. The goal of our proposal is to explore and to exploit promising regions of the search space to rapidly converge to optimal solutions. To validate the proposal, we tested 160 instances of the manufacturing cell design problem, which is a relevant problem for the industry, whose objective is to minimize the number of movements and exchanges of parts between organizational elements called cells. As a result of the experimental analysis, the authors checked that the proposal performs similarly to the default approach, but without being specifically configured for solving the problem. [ABSTRACT FROM AUTHOR]

Health facilities are care centers that receive patients with different requirements. The management of patients falls to the clinical staff trained for this activity. However, given the demands of the population, the task of managing beds is sometimes too complicated when carried out manually. In this work, we propose the design and implementation of a technological platform that provides an improved optimization approach. It manages the patient-bed allocation efficiently, by considering hospital resources given the number of units and patient diagnosis. This tool was deployed in hospitals of the Atacama regional health service in Chile, boosting the work of the clinical staff of the health facility. [ABSTRACT FROM AUTHOR]

Using the approximate algorithms, we are faced with the problem of determining the appropriate values of their input parameters, which is always a complex task and is considered an optimization problem. In this context, incorporating online control parameters is a very interesting issue. The aim is to vary the parameters during the run so that the studied algorithm can provide the best convergence rate and, thus, achieve the best performance. In this paper, we compare the performance of a self-adaptive approach for the biogeography-based optimization algorithm using the mutation rate parameter with respect to its original version and other heuristics. This work proposes altering some parameters of the metaheuristic according to its exhibited efficiency. To test this approach, we solve the set covering problem, which is a classical optimization benchmark with many industrial applications such as line balancing production, crew scheduling, service installation, databases, among several others. We illustrate encouraging experimental results, where the proposed approach is capable of reaching various global optimums for a well-known instance set taken from the Beasleys OR-Library, and sometimes, it improves the results obtained by the original version of the algorithm. [ABSTRACT FROM AUTHOR]

In this research, we present a Binary Cat Swarm Optimization for solving the Manufacturing Cell Design Problem (MCDP). This problem divides an industrial production plant into a certain number of cells. Each cell contains machines with similar types of processes or part families. The goal is to identify a cell organization in such a way that the transportation of the different parts between cells is minimized. The organization of these cells is performed through Cat Swarm Optimization, which is a recent swarm metaheuristic technique based on the behavior of cats. In that technique, cats have two modes of behavior: seeking mode and tracing mode, selected from a mixture ratio. For experimental purposes, a version of the Autonomous Search algorithm was developed with dynamic mixture ratios. The experimental results for both normal Binary Cat Swarm Optimization (BCSO) and Autonomous Search BCSO reach all global optimums, both for a set of 90 instances with known optima, and for a set of 35 new instances with 13 known optima. [ABSTRACT FROM AUTHOR]

Emotions are a critical aspect of human behavior. One widely used technique for research in emotion measurement is based on the use of EEG signals. In general terms, the first step of signal processing is the elimination of noise, which can be done in manual or automatic terms. The next step is determining the feature vector using, for example, entropy calculation and its variations to generate a classification model. It is possible to use this approach to classify theoretical models such as the Circumplex model. This model proposes that emotions are distributed in a two-dimensional circular space. However, methods to determine the feature vector are highly susceptible to noise that may exist in the signal. In this article, a new method to adjust the classifier is proposed using metaheuristics based on the black hole algorithm. The method is aimed at obtaining results similar to those obtained with manual noise elimination methods. In order to evaluate the proposed method, the MAHNOB HCI Tagging Database was used. Results show that using the black hole algorithm to optimize the feature vector of the Support Vector Machine we obtained an accuracy of 92.56% over 30 executions. [ABSTRACT FROM AUTHOR]

A case report of a 65-year-old female with a history of right total hip arthroplasty (THA) in 2007 and left THA in 2009 was presented. She consulted with our institution for the first time, on December 2013, for right hip pain and fistula on the THA incision. It was managed as a chronic infection, so a two-stage revision was performed. First-time intraoperative cultures were positive for Staphylococcus aureus (3/5) and Proteus mirabilis (2/5). Three weeks after the second half of the review, it evolved with acute fever and pain in relation to right hip. No antibiotics were used, arthrocentesis was performed, and a coagulase-negative staphylococci multisensible was isolated at the 5th day. Since the germ was different from the first revision, it was decided to perform a one-stage revision. One year after the first review, the patient has no local signs of infection and presents ESV and RPC in normal limits. The indication and management of periprosthetic infections are discussed. [ABSTRACT FROM AUTHOR]

The immunohistochemical (IHC) evaluation of epidermal growth factor 2 (HER2) for the diagnosis of breast cancer is still qualitative with a high degree of inter-observer variability, and thus requires the incorporation of complementary techniques such as fluorescent in situ hybridization (FISH) to resolve the diagnosis. Implementing automatic algorithms to classify IHC biomarkers is crucial for typifying the tumor and deciding on therapy for each patient with better performance. The present study aims to demonstrate that, using an explainable Machine Learning (ML) model for the classification of HER2 photomicrographs, it is possible to determine criteria to improve the value of IHC analysis. We trained a logistic regression-based supervised ML model with 393 IHC microscopy images from 131 patients, to discriminate between upregulated and normal expression of the HER2 protein. Pathologists' diagnoses (IHC only) vs. the final diagnosis complemented with FISH (IHC + FISH) were used as training outputs. Basic performance metrics and receiver operating characteristic curve analysis were used together with an explainability algorithm based on Shapley Additive exPlanations (SHAP) values to understand training differences. The model could discriminate amplified IHC from normal expression with better performance when the training output was the IHC + FISH final diagnosis (IHC vs. IHC + FISH: area under the curve, 0.94 vs. 0.81). This may be explained by the increased analytical impact of the membrane distribution criteria over the global intensity of the signal, according to SHAP value interpretation. The classification model improved its performance when the training input was the final diagnosis, downplaying the weighting of the intensity of the IHC signal, suggesting that to improve pathological diagnosis before FISH consultation, it is necessary to emphasize subcellular patterns of staining. [ABSTRACT FROM AUTHOR]

In the world of optimization, especially concerning metaheuristics, solving complex problems represented by applying big data and constraint instances can be difficult. This is mainly due to the difficulty of implementing efficient solutions that can solve complex optimization problems in adequate time, which do exist in different industries. Big data has demonstrated its efficiency in solving different concerns in information management. In this paper, an approach based on multiprocessing is proposed wherein clusterization and parallelism are used together to improve the search process of metaheuristics when solving large instances of complex optimization problems, incorporating collaborative elements that enhance the quality of the solution. The proposal deals with machine learning algorithms to improve the segmentation of the search space. Particularly, two different clustering methods belonging to automatic learning techniques, are implemented on bio-inspired algorithms to smartly initialize their solution population, and then organize the resolution from the beginning of the search. The results show that this approach is competitive with other techniques in solving a large set of cases of a well-known NP-hard problem without incorporating too much additional complexity into the metaheuristic algorithms. [ABSTRACT FROM AUTHOR]

Metaheuristics are intelligent problem-solvers that have been very efficient in solving huge optimization problems for more than two decades. However, the main drawback of these solvers is the need for problem-dependent and complex parameter setting in order to reach good results. This paper presents a new cuckoo search algorithm able to self-adapt its configuration, particularly its population and the abandon probability. The self-tuning process is governed by using machine learning, where cluster analysis is employed to autonomously and properly compute the number of agents needed at each step of the solving process. The goal is to efficiently explore the space of possible solutions while alleviating human effort in parameter configuration. We illustrate interesting experimental results on the well-known set covering problem, where the proposed approach is able to compete against various state-of-the-art algorithms, achieving better results in one single run versus 20 different configurations. In addition, the result obtained is compared with similar hybrid bio-inspired algorithms illustrating interesting results for this proposal. [ABSTRACT FROM AUTHOR]

Bio-inspired computing is an engaging area of artificial intelligence which studies how natural phenomena provide a rich source of inspiration in the design of smart procedures able to become powerful algorithms. Many of these procedures have been successfully used in classification, prediction, and optimization problems. Swarm intelligence methods are a kind of bio-inspired algorithm that have been shown to be impressive optimization solvers for a long time. However, for these algorithms to reach their maximum performance, the proper setting of the initial parameters by an expert user is required. This task is extremely comprehensive and it must be done in a previous phase of the search process. Different online methods have been developed to support swarm intelligence techniques, however, this issue remains an open challenge. In this paper, we propose a hybrid approach that allows adjusting the parameters based on a state deducted by the swarm intelligence algorithm. The state deduction is determined by the classification of a chain of observations using the hidden Markov model. The results show that our proposal exhibits good performance compared to the original version. [ABSTRACT FROM AUTHOR]

In this paper, we integrate the autonomous search paradigm on a swarm intelligence algorithm in order to incorporate the auto-adjust capability on parameter values during the run. We propose an independent procedure that begins to work when it detects a stagnation in a local optimum, and it can be applied to any population-based algorithms. For that, we employ the autonomous search technique which allows solvers to automatically re-configure its solving parameters for enhancing the process when poor performances are detected. This feature is dramatically crucial when swarm intelligence methods are developed and tested. Finding the best parameter values that generate the best results is known as an optimization problem itself. For that, we evaluate the behavior of the population size to autonomously be adapted and controlled during the solving time according to the requirements of the problem. The proposal is testing on the dolphin echolocation algorithm which is a recent swarm intelligence algorithm based on the dolphin feature to navigate underwater and identify prey. As an optimization problem to solve, we test a machine-part cell formation problem which is a widely used technique for improving production flexibility, efficiency, and cost reduction in the manufacturing industry decomposing a manufacturing plant in a set of clusters called cells. The goal is to design a cell layout in such a way that the need for moving parts from one cell to another is minimized. Using statistical non-parametric tests, we demonstrate that the proposed approach efficiently solves 160 well-known cell manufacturing instances outperforming the classic optimization algorithm as well as other approaches reported in the literature, while keeping excellent robustness levels. [ABSTRACT FROM AUTHOR]

Metaheuristics are smart problem solvers devoted to tackling particularly large optimization problems. During the last 20 years, they have largely been used to solve different problems from the academic as well as from the real-world. However, most of them have originally been designed for operating over real domain variables, being necessary to tailor its internal core, for instance, to be effective in a binary space of solutions. Various works have demonstrated that this internal modification, known as binarization, is not a simple task, since the several existing binarization ways may lead to very different results. This of course forces the user to implement and analyze a large list of binarization schemas for reaching good results. In this paper, we explore two efficient clustering methods, namely KMeans and DBscan to alter a metaheuristic in order to improve it, and thus do not require on the knowledge of an expert user for identifying which binarization strategy works better during the run. Both techniques have widely been applied to solve clustering problems, allowing us to exploit useful information gathered during the search to efficiently control and improve the binarization process. We integrate those techniques to a recent metaheuristic called Crow Search, and we conduct experiments where KMeans and DBscan are contrasted to 32 different binarization methods. The results show that the proposed approaches outperform most of the binarization strategies for a large list of well-known optimization instances. [ABSTRACT FROM AUTHOR]

Background: The constant increase of factors associated with the presence of resistant strains, makes empirical antibiotic selection a challenge in patients hospitalized for community-acquired urinary tract infection., Aim: We characterized the bacteria and their antimicrobial susceptibility pattern in cultures obtained from adult patients that needed hospitalization for this disease in two tertiary hospitals in Santiago, Chile., Methods: We conducted a prospective cross-sectional study in adults hospitalized for community-acquired urinary tract infection between 2017 and 2022. All patients with positive urine cultures were included in the analysis., Results: A total of 830 patients were included. Escherichia coli was the most frequent infectious agent (68.1%), followed by Klebsiella spp. (17.7%) and Enterococcus faecalis (6.7%). Among Enterobacteriaceae strains, 35.2%, 19.7% and 27.2% were resistant to first, second and third-generation cephalosporin, respectively. 36.9% were resistant to ciprofloxacin and 1.8% to amikacin. Gram-positive bacteria were resistant to oxacillin and ampicillin in 25% and 18%, respectively., Conclusion: We detected a high prevalence of community-acquired urinary tract infections caused by bacteria resistant to commonly used antibiotics in adult patients that need to be hospitalized.

The immunohistochemical (IHC) evaluation of epidermal growth factor 2 (HER2) for the diagnosis of breast cancer is still qualitative with a high degree of inter-observer variability, and thus requires the incorporation of complementary techniques such as fluorescent in situ hybridization (FISH) to resolve the diagnosis. Implementing automatic algorithms to classify IHC biomarkers is crucial for typifying the tumor and deciding on therapy for each patient with better performance. The present study aims to demonstrate that, using an explainable Machine Learning (ML) model for the classification of HER2 photomicrographs, it is possible to determine criteria to improve the value of IHC analysis. We trained a logistic regression-based supervised ML model with 393 IHC microscopy images from 131 patients, to discriminate between upregulated and normal expression of the HER2 protein. Pathologists' diagnoses (IHC only) vs. the final diagnosis complemented with FISH (IHC + FISH) were used as training outputs. Basic performance metrics and receiver operating characteristic curve analysis were used together with an explainability algorithm based on Shapley Additive exPlanations (SHAP) values to understand training differences. The model could discriminate amplified IHC from normal expression with better performance when the training output was the IHC + FISH final diagnosis (IHC vs. IHC + FISH: area under the curve, 0.94 vs. 0.81). This may be explained by the increased analytical impact of the membrane distribution criteria over the global intensity of the signal, according to SHAP value interpretation. The classification model improved its performance when the training input was the final diagnosis, downplaying the weighting of the intensity of the IHC signal, suggesting that to improve pathological diagnosis before FISH consultation, it is necessary to emphasize subcellular patterns of staining., Competing Interests: The authors declare that they have no competing interests., (Copyright: © Cordova et al.)

Purpose: To describe patient-reported outcomes, radiological results, and revision to total hip replacement in patients with hip dysplasia that underwent periacetabular osteotomy as isolated treatment or concomitant with hip arthroscopy., Methods: Case series study. Between 2014 and 2017, patients were included if they complained of hip pain and had a lateral center-edge angle ≤ of 20°. Exclusion criteria included an in-maturate skeleton, age of 40 or older, previous hip surgery, concomitant connective tissue related disease, and Tönnis osteoarthritis grade ≥ 1. All patients were studied before surgery with an anteroposterior pelvis radiograph, false-profile radiograph, and magnetic resonance imaging. Magnetic resonance imaging was used to assess intraarticular lesions, and if a labral or chondral injury was found, concomitant hip arthroscopy was performed. The non-parametric median test for paired data was used to compare radiological measures (anterior and lateral center-edge angle, Tönnis angle, and extrusion index) after and before surgery. Survival analysis was performed using revision to total hip arthroplasty as a failure. Kaplan Meier curve was estimated. The data were processed using Stata., Results: A total of 15 consecutive patients were included; 14 (93%) were female patients. The median follow-up was 3.5 years (range, 2 to 8 years). The median age was 20 (range 13 to 32). Lateral center-edge angle, Tönnis angle, and extrusion index correction achieved statistical significance. Seven patients (47%) underwent concomitant hip arthroscopy; three of them (47%) were bilateral (10 hips). The labrum was repaired in six cases (60%). Three patients (15%) required revision with hip arthroplasty, and no hip arthroscopy-related complications are reported in this series., Conclusion: To perform a hip arthroscopy concomitant with periacetabular osteotomy did not affect the acetabular correction. Nowadays, due to a lack of conclusive evidence, a case by case decision seems more appropriate to design a comprehensive treatment.

Organizational learning is a key element for the development of organizations. School organizations are not exempt from this challenge and they currently face a highly dynamic and demanding context of education policies that emphasize the school's ability to learn. Thus, research on organizational learning in educational contexts requires valid instruments that are sensitive to the specifics of schools as organizations. In this study, we adapted and validated a scale of organizational learning in a sample of 119 Chilean municipal schools (N= 1,545). The results suggest a structural model made up of three factors: culture of learning, strategic clarity, and group learning. These factors predicted dimensions of educational achievement, as measured through the National Assessment System of Educational Achievement (SNED). Results are discussed in view of the literature on school improvement.