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Your search keyword '"Nguyen, Hieu T."' showing total 359 results
Start Over Author "Nguyen, Hieu T." Publication Type Academic Journals
359 results on '"Nguyen, Hieu T."'

2. Solvent engineering for scalable fabrication of perovskite/silicon tandem solar cells in air

Author

Zheng, Xuntian, Kong, Wenchi, Wen, Jin, Hong, Jiajia, Luo, Haowen, Xia, Rui, Huang, Zilong, Luo, Xin, Liu, Zhou, Li, Hongjiang, Sun, Hongfei, Wang, Yurui, Liu, Chenshuaiyu, Wu, Pu, Gao, Han, Li, Manya, Bui, Anh Dinh, Mo, Yi, Zhang, Xueling, Yang, Guangtao, Chen, Yifeng, Feng, Zhiqiang, Nguyen, Hieu T., Lin, Renxing, Li, Ludong, Gao, Jifan, and Tan, Hairen

Published
2024
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12. Safety and immunogenicity of Nanocovax, a SARS-CoV-2 recombinant spike protein vaccine: Interim results of a double-blind, randomised controlled phase 1 and 2 trial

Author

Nguyen, Thuy P., Do, Quyet, Phan, Lan T., Dinh, Duc V., Khong, Hiep, Hoang, Luong V., Nguyen, Thuong V., Pham, Hung N., Chu, Men V., Nguyen, Toan T., Pham, Quang D., Le, Tri M., Trang, Tuyen N.T., Dinh, Thanh T., Vo, Thuong V., Vu, Thao T., Nguyen, Quynh B.P., Phan, Vuong T., Nguyen, Luong V., Nguyen, Giang T., Tran, Phong M., Nghiem, Thuan D., Tran, Tien V., Nguyen, Tien G., Tran, Tuynh Q., Nguyen, Linh T., Do, Anh T., Nguyen, Dung D., Ho, Son A., Nguyen, Viet T., Pham, Dung T., Tran, Hieu B., Vu, Son T., Hoang, Su X., Do, Trung M., Ngoc, Hoan Vu, Nguyen, Xuan T., Le, Giang Q., Tran, Ton, Cao, Thang M., Dao, Huy M., Nguyen, Thao T.T., Doan, Uyen Y, Le, Vy T.T., Tran, Linh P., Nguyen, Ngoc M., Nguyen, Ngoc T., Pham, Hang T.T., Nguyen, Quan H., Nguyen, Hieu T., Nguyen, Hang L.K., Tran, Vinh T., Tran, Mai T.N., Nguyen, Truc T.T., Ha, Phat T., Huynh, Hieu T., Nguyen, Khanh D., Thuan, Ung T., Doan, Chung C., and Do, Si M.

Published
2022
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19. An unfolded protein-induced conformational switch activates mammalian IRE1.

Author

Karagöz, G Elif, Acosta-Alvear, Diego, Nguyen, Hieu T, Lee, Crystal P, Chu, Feixia, and Walter, Peter

Subjects
Humans, Endoribonucleases, Protein-Serine-Threonine Kinases, Peptides, Chromatography, Liquid, Magnetic Resonance Spectroscopy, Allosteric Regulation, Protein Conformation, Protein Binding, Protein Folding, Models, Molecular, Tandem Mass Spectrometry, Protein Multimerization, ER-stress, IRE1, biochemistry, biophysics, mouse, nuclear magnetic resonance spectroscopy, structural biology, unfolded protein response, Chromatography, Liquid, Models, Molecular, Biochemistry and Cell Biology
Abstract

The unfolded protein response (UPR) adjusts the cell's protein folding capacity in the endoplasmic reticulum (ER) according to need. IRE1 is the most conserved UPR sensor in eukaryotic cells. It has remained controversial, however, whether mammalian and yeast IRE1 use a common mechanism for ER stress sensing. Here, we show that similar to yeast, human IRE1α's ER-lumenal domain (hIRE1α LD) binds peptides with a characteristic amino acid bias. Peptides and unfolded proteins bind to hIRE1α LD's MHC-like groove and induce allosteric changes that lead to its oligomerization. Mutation of a hydrophobic patch at the oligomerization interface decoupled peptide binding to hIRE1α LD from its oligomerization, yet retained peptide-induced allosteric coupling within the domain. Importantly, impairing oligomerization of hIRE1α LD abolished IRE1's activity in living cells. Our results provide evidence for a unifying mechanism of IRE1 activation that relies on unfolded protein binding-induced oligomerization.

Published
2017

23. Ethnic Gaps in Child Education Outcomes in Vietnam: An Investigation Using Young Lives Data

Author

Nguyen, Hieu T. M.

Abstract

There are large gaps in child education outcomes between the Kinh majority and non-Kinh minorities in Vietnam. This paper seeks to understand the reasons for these ethnic gaps. The examination employs Probit and multilevel regression models, and associated decomposition techniques. The results show that Vietnam's ethnic gap in school enrolment is mostly attributable to household characteristics such as household expenditure and father's education. Gaps in schooling progress and performance are explained by a broader set of variables such as child, household, commune, school, and peer characteristics.

Published
2019
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35. Phosphatase specificity principles uncovered by MRBLE:Dephos and global substrate identification.

Author

Hein, Jamin B, Nguyen, Hieu T, Garvanska, Dimitriya H, Nasa, Isha, Kruse, Thomas, Feng, Yinnian, Lopez Mendez, Blanca, Davey, Norman, Kettenbach, Arminja N, Fordyce, Polly M, and Nilsson, Jakob

Subjects
*PHOSPHOPROTEIN phosphatases, *AMINO acid residues, *PEPTIDES
Abstract

Phosphoprotein phosphatases (PPPs) regulate major signaling pathways, but the determinants of phosphatase specificity are poorly understood. This is because methods to investigate this at scale are lacking. Here, we develop a novel in vitro assay, MRBLE:Dephos, that allows multiplexing of dephosphorylation reactions to determine phosphatase preferences. Using MRBLE:Dephos, we establish amino acid preferences of the residues surrounding the dephosphorylation site for PP1 and PP2A‐B55, which reveals common and unique preferences. To compare the MRBLE:Dephos results to cellular substrates, we focused on mitotic exit that requires extensive dephosphorylation by PP1 and PP2A‐B55. We use specific inhibition of PP1 and PP2A‐B55 in mitotic exit lysates coupled with phosphoproteomics to identify more than 2,000 regulated sites. Importantly, the sites dephosphorylated during mitotic exit reveal key signatures that are consistent with MRBLE:Dephos. Furthermore, integration of our phosphoproteomic data with mitotic interactomes of PP1 and PP2A‐B55 provides insight into how binding of phosphatases to substrates shapes dephosphorylation. Collectively, we develop novel approaches to investigate protein phosphatases that provide insight into mitotic exit regulation. Synopsis: MRBLE:Dephos a new method for high‐throughput investigation of peptide dephosphorylation using spectral encoded beads. Using this method, the active site preferences of PP1 and PP2A‐B55 are investigated and compared to mitotic exit substrates identified by phosphoproteomics. MRBLE:Dephos is a novel high‐throughput dephosphorylation method.MRBLE:Dephos provides insights into PP1 and PP2A‐B55 sequence preferences.Mitotic exit substrate screens for PP1 and PP2A‐B55 identifies thousands of regulated sites.Binding of PP1 to RVxF motifs can modulate active site preferences. [ABSTRACT FROM AUTHOR]

Published
2023
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37. D2D COMMUNICATION NETWORK WITH THE ASSISTANCE OF POWER BEACON UNDER THE IMPACT OF CO-CHANNEL INTERFERENCES AND EAVESDROPPER: PERFORMANCE ANALYSIS.

Author

Bui Vu MINH, Tran Hoang Quang MINH, Van-Duc PHAN, and NGUYEN, Hieu T.

Subjects
CO-channel interference, TELECOMMUNICATION systems, ENERGY budget (Geophysics), ENERGY harvesting
Abstract

In this paper, we study and demonstrate the performance analysis of a device-to-device (D2D) communication network. Specifically, a source node transmits data to the destination node using the power beacon's harvested energy in order to overcome the limited energy budget. Besides, an eavesdropper located in the proximal region of a source is trying to overhear secure information. Notably, both eavesdropper and destination are affected by co-channel interferences from other sources when they utilize the same frequency. By considering the above discussions, we derived the closedform expressions for outage probability (OP), intercept probability (IP), and secrecy outage probability (SOP) in connection with using the system model. The derived analytical expressions are then verified by utilizing both simulation and numerical results. Finally, the intensive parameters' influences on the OP, IP, and SOP are also investigated. [ABSTRACT FROM AUTHOR]

Published
2023
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38. Synthesis of Black Phosphorene Quantum Dots from Red Phosphorus.

Author

Shutt, Rebecca R. C., Ramireddy, Thrinathreddy, Stylianidis, Evgenios, Di Mino, Camilla, Ingle, Rebecca A., Ing, Gabriel, Wibowo, Ary A., Nguyen, Hieu T., Howard, Christopher A., Glushenkov, Alexey M., Stewart, Andrew, and Clancy, Adam J.

Subjects
PHOSPHORENE, PHOSPHORUS, MONOMOLECULAR films, LIQUID ammonia, TRANSMISSION electron microscopy, QUANTUM dots, IMAGE transmission
Abstract

Black phosphorene quantum dots (BPQDs) are most commonly derived from high‐cost black phosphorus, while previous syntheses from the low‐cost red phosphorus (Pred) allotrope are highly oxidised. Herein, we present an intrinsically scalable method to produce high quality BPQDs, by first ball‐milling Pred to create nanocrystalline Pblack and subsequent reductive etching using lithium electride solvated in liquid ammonia. The resultant ~25 nm BPQDs are crystalline with low oxygen content, and spontaneously soluble as individualized monolayers in tertiary amide solvents, as directly imaged by liquid‐phase transmission electron microscopy. This new method presents a scalable route to producing quantities of high quality BPQDs for academic and industrial applications. [ABSTRACT FROM AUTHOR]

Published
2023
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45. Hybrid Alkali Salt Catalysts‐Promoted CVD Growth of 2D MoSe2–WSe2 and WSe2–MoSe2 Lateral Heterostructures.

Author

Wibowo, Ary Anggara, Tebyetekerwa, Mike, Bui, Anh Dinh, Truong, Thien N., Saji, Sandra, Kremer, Felipe, Yang, Zhongshu, Yin, Zongyou, Lu, Yuerui, Macdonald, Daniel, and Nguyen, Hieu T.

Subjects
HETEROSTRUCTURES, FUSED salts, CHEMICAL vapor deposition, SODIUM nitrate, OPTOELECTRONIC devices, SALT
Abstract

A scalable growth of atomically‐thin 2D transition metal dichalcogenides (TMDs) with defect‐free large‐area surfaces is crucial for developing high‐performing optoelectronic devices. Herein, a method to grow large‐area, high‐quality MoSe2 monolayers, MoSe2–WSe2, and WSe2–MoSe2 lateral heterostructures using molten salt‐based chemical vapor deposition (CVD) is systematically reported. First, effects of isolated inorganic (sodium chloride (NaCl) and sodium nitrate (NaNO3)), organic (Perylene–3,4,9,10–tetracarboxylic acid tetrapotassium salt (PTAS), mixed inorganic (NaCl/NaNO3), and hybrid organic–inorganic (PTAS/NaCl/NaNO3) salt catalysts on the CVD growth and optoelectronic quality of MoSe2 monolayers and their lateral heterostructures with WSe2 in MoSe2–WSe2 and WSe2–MoSe2 assemblies are investigated. Results show that molten salt catalysts (NaCl/NaNO3 and PTAS/NaCl/NaNO3) support high‐quality, large‐area growth of MoSe2 monolayers with low defect density. The mixed inorganic salt supports growth of MoSe2–WSe2 lateral heterostructures but not their counterpart. Meanwhile, WSe2–MoSe2 lateral heterostructures are optimally grown, supported by the hybrid organic–inorganic salt. These results are ascribed to the difference in the associated kinetic and thermodynamic mechanisms for the growths of MoSe2 and WSe2 as starting materials. Last, it is confirmed that optoelectronic quality of realized heterostructures and monolayers is improved compared to their mechanically exfoliated counterparts. The obtained high‐quality, large‐area 2D TMD heterostructures can be useful for various optoelectronic applications. [ABSTRACT FROM AUTHOR]

Published
2023
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46. Two new antidiabetic xanthones from the twigs of Garcinia oblongifolia.

Author

Bui, Dzung N., Nguyen, Ly T. T., Nguyen, Le-Thu T., Ngo, Ngoc T. N., Tran, Phuong T., Nguyen, Hieu T., Dang, Linh T. N., Nguyen, Lien-Hoa D., and Trinh, Binh T. D.

Subjects
GARCINIA, TWIGS, HYPOGLYCEMIC agents, GLUCOSIDASES, TYPE 2 diabetes, ALPHA-glucosidases
Abstract

Two new xanthones, oblongixanthones I (1) and J (2), and seven known compounds (3–9), were isolated from an EtOAc extract of the twigs of Garcinia oblongifolia. Their structures were elucidated using spectroscopic methods, mainly 1 D and 2 D NMR. The antidiabetic effects of the two new compounds were evaluated using α-glucosidase and PTP1B inhibition assays. Both compounds displayed strong inhibition towards α-glucosidase with IC50 values of 258.7 ± 49.3 and 187.1 ± 27.5 μM, respectively (compared with acarbose, IC50 = 900.0 ± 3.0 μM) and moderate effects against PTP1B with IC50 values of 93.9 ± 12.3 and 64.1 ± 5.8 μM, respectively (compared with RK682, IC50 = 4.4 ± 0.3 l μM). [ABSTRACT FROM AUTHOR]

Published
2023
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