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As tourism research has paid limited attention to children, this study investigates children's reactions to tourism development, focusing on their unique viewpoints on the World Heritage Site of Dubrovnik, Croatia. It employed cognitive neuroscience methods with 397 participants, revealing that, despite their preference for sustainable tourism scenarios, children exhibit a notable fixation on images emblematic of overtourism and associated challenges, particularly overcrowding. When exposed to sustainable tourism photographs, there was an observable increase in physiological arousal, albeit not as pronounced as when confronted with an overtourism scenario. Intriguingly, regardless of the scenario, children predominantly expressed neutral emotions. Within the sustainable tourism context, gender differences manifest as girls exhibiting lower levels of place attachment. Furthermore, inner-city residents exhibit diminished levels of nature connectedness, and emotions are indirectly linked to nature connectedness, place attachment, or pro-environmental behaviour. Conversely, in the unsustainable scenario, older children and inner-city residents exhibited a heightened sense of neutrality towards overtourism-related concerns, whereas those outside the inner city displayed a stronger affinity for nature connectedness. Positive emotions were negatively associated with nature connectedness and pro-environmental behaviour but positively associated with place attachment. Accordingly, this study advocates a more inclusive and sustainable future through children's empowerment in tourism development. [ABSTRACT FROM AUTHOR]

Copyright of Bulletin of Educational Research is the property of National Taiwan Normal University, Department of Education and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

In situations where animal models (AMs) are necessary, as in the field of neuroscience, a strong culture of care must be supported and established. The pivotal question remains: how can we uphold a robust "culture of care"? In the multifaceted domain of neuroscience research, AMs traverse a spectrum shaped by conflicting viewpoints, anthropocentrism and pathocentrism, where established scientific norms intersect with ethical deliberations. Anthropocentrism, representative of conventional scientific approaches, may prioritize scientific goals potentially to the detriment of animal welfare. Conversely, pathocentrism places significant importance on the ethical treatment and well-being of AMs. This divergence of approach prompts the imperative development of a robust culture of care framework within research institutions, advocating for animal welfare, ethical responsibility, and adherence to regulatory standards. In this review, we refer to a European view of animal care, discussing internationally valid concepts that find rebuttal in the current European legislation. This review meticulously analyzes the many facets of the culture of care, particularly for neuroscience studies involving AMs, illustrating the principles, practices, and collaborations critical to overcoming ethical expectations. This commitment increases credibility and builds trust in the public and research spheres, underscoring the critical importance of a culture of care in the ethics of neuroscience research. [ABSTRACT FROM AUTHOR]

In situations where animal models (AMs) are necessary, as in the field of neuroscience, a strong culture of care must be supported and established. The pivotal question remains: how can we uphold a robust “culture of care”? In the multifaceted domain of neuroscience research, AMs traverse a spectrum shaped by conflicting viewpoints, anthropocentrism and pathocentrism, where established scientific norms intersect with ethical deliberations. Anthropocentrism, representative of conventional scientific approaches, may prioritize scientific goals potentially to the detriment of animal welfare. Conversely, pathocentrism places significant importance on the ethical treatment and well-being of AMs. This divergence of approach prompts the imperative development of a robust culture of care framework within research institutions, advocating for animal welfare, ethical responsibility, and adherence to regulatory standards. In this review, we refer to a European view of animal care, discussing internationally valid concepts that find rebuttal in the current European legislation. This review meticulously analyzes the many facets of the culture of care, particularly for neuroscience studies involving AMs, illustrating the principles, practices, and collaborations critical to overcoming ethical expectations. This commitment increases credibility and builds trust in the public and research spheres, underscoring the critical importance of a culture of care in the ethics of neuroscience research.

Abstract The National Institutes of Health is renowned for being the largest funder of biomedical research in the world. Although it also houses unique research laboratories and clinics on its campuses around the United States, the National Institutes of Health Intramural Research Program is much less well‐known than its extramural enterprise. The Intramural Research Program provides many outstanding opportunities for research‐intensive careers and training and includes a vibrant and diverse community of developmental neurobiology and child neurology investigators.

Cannulation implantation into the cisterna magna is an important procedure in cerebrospinal fluid (CSF) sampling and intracranial pressure (ICP) monitoring. The disadvantages of existing techniques include the risk of brain damage, compromised muscle mobility, and the complexity of the procedures. In the present study, the authors describe a modified, simple, and reliable procedure for long-term cannulation implantation into the cisterna magna in rats. The device consists of four parts: the puncture segment, the connection segment, the fixing segment, and the external segment. Intraoperative ICP monitoring and postoperative computed tomography (CT) scans were performed, which confirmed the accuracy and safety of this method. There were no limitations on the daily activities of the rats when long-term drainage was carried out for 1 week. This new technique offers an improved method of cannulation and will be a potentially useful method for CSF sampling and ICP monitoring in neuroscience research. [ABSTRACT FROM AUTHOR]

In neuroscience research, longitudinal data are often analysed using analysis of variance (ANOVA) and multivariate analysis of variance (MANOVA) for repeated measures (rmANOVA/rmMANOVA). However, these analyses have special requirements: The variances of the differences between all possible pairs of within‐subject conditions (i.e., levels of the independent variable) must be equal. They are also limited to fixed repeated time intervals and are sensitive to missing data. In contrast, other models, such as the generalized estimating equations (GEE) and the generalized linear mixed models (GLMM), suggest another way to think about the data and the studied phenomenon. Instead of forcing the data into the ANOVAs assumptions, it is possible to design a flexible/personalized model according to the nature of the dependent variable. We discuss some advantages of GEE and GLMM as alternatives to rmANOVA and rmMANOVA in neuroscience research, including the possibility of using different distributions for the parameters of the dependent variable, a better approach for different time length points, and better adjustment to missing data. We illustrate these advantages by showing a comparison between rmANOVA and GEE in a real example and providing the data and a tutorial code to reproduce these analyses in R. We conclude that GEE and GLMM may provide more reliable results when compared to rmANOVA and rmMANOVA in neuroscience research, especially in small sample sizes with unbalanced longitudinal designs with or without missing data. [ABSTRACT FROM AUTHOR]

Interpersonal trust is essential for societal well-being, underpinning relationships from individuals to institutions. Neuroscience research on trust has advanced swiftly since 2001. While quantitative reviews, meta-analyses, and theoretical frameworks have effectively synthesized trust neuroscience research, bibliometric analysis remains underutilized. Our bibliometric analysis aimed to provide a comprehensive overview of trust neuroscience's current state and future directions by examining its historical development, key contributors, geographic distribution, methodological paradigms, influential works, thematic trends, and overall impact. This field has been characterized by the input of a few key contributors through international collaboration, with significant contributions from the U.S., China, the Netherlands, and Germany. Research predominantly utilizes the trust game and fMRI, with a rising focus on neural networks, general trust, and differentiating behavioral from attitudinal trust. Integrating insights from psychology, economics, and sociology, this interdisciplinary field holds promise for advancing our understanding of trust through a neurobiological lens. In conclusion, our bibliographic literature review provides valuable insights and guidance for scholars, spotlighting potential avenues for further investigation in this fast-growing field., Competing Interests: Declaration of Competing Interest The authors are unaware of any conflicts of interest, financial or otherwise., (Copyright © 2024 Elsevier Ltd. All rights reserved.)

Background & objectives We aimed to assess the impact of COVID-19-related disruptions on ongoing and future projects related to neuroscience research and young researchers in India. Methods We conducted a countrywide online survey using a structured, self-administered questionnaire involving medical trainees, post-doctoral fellows, PhD students, early career faculty members and basic neuroscience researchers. The purpose was to assess the impact of the COVID-19 pandemic on the respondents' ongoing/planned research activities and capture their concerns related to future research. Results Five hundred and four valid responses were analyzed. More than three-fourths of the respondents were in their early careers - 64.1 per cent were resident doctors, and 19.8 per cent were early career consultants. Maximum responses were received from respondents working in neurology (228; 45.2%), followed by psychiatry (192; 38.1%) and neurosurgery (49; 9.7%). More than three-fourths [83.5%, 95% confidence interval (CI): 0.8-0.867] of the respondents reported that the pandemic had affected their research. About one-third of the respondents (171; 33.9%) reported delays in completing research studies. Respondents adapted to the pandemic's circumstances by making methodological changes in their research (155; 30.8%). Most respondents (301; 59.6%) reported being diverted from their traditional work settings to COVID-19-related clinical services. Respondents conducting prospective studies and randomized controlled trials and those diverted to COVID-related services were significantly more likely to report the adverse research impact. Interpretation & conclusions In our survey, an overwhelming majority of the respondents reported that the pandemic adversely impacted their study. This trend was independent of sex, designation, and research output of individual subjects. The serious impact of the COVID-19 pandemic on neurosciences research warrants the attention and concerted efforts of the research supervisors, institutional heads, funding agencies and other stakeholders.

Copyright of Clinical Neuroscience / Ideggyógyászati Szemle is the property of LifeTime Media Kft. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

This study is aimed at evaluating the outcomes of mind-body transformation therapy (MBT-T), previously known as the creative psychosocial genomic healing experience© (CPGHE). The intervention was aimed at reducing the perceived level of stress in two non-clinical groups of students with different educational levels and different expertise in the domain of well-being. Whereas participants from the first group were first-year university students, participants from the second group were students attending a post-graduate program in psychotherapy. All participants (n = 159) were exposed to a single session of MBT-T, each group in a separate session. The results of two paired-samples t-tests, conducted separately on the two samples, showed that there was a statistically significant reduction in the participants’ perceived level of stress between pre- and post-intervention states in both samples (t88 = 5.39, p < 0.001; t53 = 4.56, p < 0.001 respectively). The results, therefore, showed that a single session of MBT-T was beneficial in reducing the perceived level of stress in both first-year university students and students attending a post-graduate program in psychotherapy, regardless of educational level and expertise in the domain of well-being.

The field of neuroscience research in Africa has witnessed significant advancements in recent years, contributing to understanding the brain and neurological disorders. This paper provides an overview of the current state of neuroscience research in Africa, highlighting the progress made, ongoing efforts, and the challenges researchers face. Despite limited resources and funding constraints, African scientists have made remarkable strides in various areas of neuroscience. Collaborative networks and international partnerships have been crucial in advancing education, research infrastructure, and capacity building in the field. Institutions in countries such as Egypt, Ghana, South Africa, Nigeria, Tunisia, and Morocco have emerged as key hubs for neuroscience research, fostering a growing community of researchers dedicated to unravelling the complexities of the brain. Efforts in neuroscience research have encompassed diverse domains, including neurogenomics, neuroimaging, neurophysiology, neurorehabilitation, and neuroepidemiology. Studies have focused on investigating genetic factors underlying neurological conditions, exploring the neural mechanisms of cognition and behaviour, and developing innovative therapeutic approaches for neurological disorders. However, challenges persist in the African neuroscience research landscape. Limited funding remains a significant barrier, hindering the establishment of well-equipped laboratories, access to advanced technologies, and support for research projects. Addressing these concerns is crucial to ensure research outcomes' integrity, validity, and relevance. Looking ahead, strategic interventions are required to address these challenges and further advance neuroscience research in Africa., Competing Interests: The authors declare that they have no conflicts of interest., (Copyright © 2023 The Author(s). Published by Wolters Kluwer Health, Inc.)

Identifying neurocognitive mechanisms involved in individuals experiencing eating disorder (ED) symptoms may be important for preventing EDs and improving rates of recovery. The present pilot study assessed how cognitive functioning may be associated with ED symptoms in college students (N = 41). Cognitive functioning was examined using electroencephalography during an auditory response inhibition task to measure the P3 component of event‐related potentials. Multiple regression analysis revealed that longer P3 latencies in the frontal region of the cortex were significantly and linearly associated with greater ED symptoms F(3, 37) = 13.62, p < .001, R2 = 0.525, Adj. R2 = 0.486. These pilot findings build upon prior work in clinical samples in that they indicate that functional brain differences are observable across a wide span of ED symptoms, not just in those with diagnosed ED. The present findings provide support for further exploration of changes in P3 latencies among individuals with ED symptoms to enhance our understanding of neural mechanisms that may pertain to the dimensional aspects of disordered eating attitudes and behaviors. [ABSTRACT FROM AUTHOR]

Perceived dyscognition or fibrofog has been ranked as one major contributor of distress in fibromyalgia (FM). The Multidimensional Inventory of Subjective Cognitive Impairment (MISCI) was devised as a brief and comprehensive self‐report measure of cognitive function in FM. The main objective of the present study was to assess the psychometric properties of the Spanish version of the MISCI. One hundred and twenty patients with FM were included, and dimensionality, reliability, and validity of the MISCI were evaluated. Data from brain imaging (N = 61) were also used in validity analyses. Known‐groups validity was evaluated by including a subset of 45 patients without FM in partial/total remission from depression. Sensitivity to change was assessed after a mindfulness‐based intervention. Spanish version of the MISCI exhibited a one‐factor structure, excellent internal consistency, and good convergent validity with symptomatology and gray matter volumes in anterior and middle cingulate cortices. Significant improvements in MISCI scores after a mindfulness‐based intervention were reported. An additive effect of FM and depression regarding MISCI scores was also observed. Self‐reported depression, anxiety, and problems in balance predicted the 38% of the MISCI variance. The Spanish version of the MISCI is a valuable instrument to include in FM research and clinical practice. [ABSTRACT FROM AUTHOR]

Pain is an essential physiological defense against danger, be it external, from the environment, or internal, arising from within the body. The initiation of this acute defensive pain is driven by activation in the periphery of the terminals of high threshold nociceptor sensory neurons by intense or irritant noxious stimuli and comprises both the distinct unpleasant sensation of pain and protective motor responses. Clinical pain, is though, very different from the immediate detection of and reaction to noxious stimuli, it includes ongoing pain and development of pain hypersensitivity in the presence of tissue damage, after nerve injury and in some cases, in the absence of any peripheral pathology. In all these situations, a prominent feature and sometimes prime driver of the pain, is an altered modulation of pain processing within the central nervous system, an amplification consequent on increased excitability and/or reduced inhibition in specific neural networks, which constitute the phenomenon of central sensitization. Recognition of the importance of central sensitization for the maintenance and manifestation of clinical pain states has led to an appreciation that such pain typically is an expression of an altered/disease state of nociceptive circuits in the central nervous system, one triggered but not necessarily sustained by peripheral injury, rather than only a symptom of some ongoing peripheral pathology, and treatment needs to be targeted accordingly. [ABSTRACT FROM AUTHOR]

This paper summarizes a review of articles that have explored the relationship between obstructive sleep apnea ( OSA), brain infractions, and cognitive dysfunction. The anomalies in brain hemodynamics, brain atrophy, and cognitive dysfunction resulting from OSA are reviewed. The effectiveness of continuous positive airway pressure ( CPAP) treatment on the reversibility of structural and neurobehavioral deficits is also presented. The articles were selected based on a systematic search on PubMed and Medline databases using the key words 'sleep apnea, OSA, hypoxia, sleep fragmentation, cerebral hemodynamics, metabolism, brain structure, cognition, memory, quality of life, neuropsychological deficits, and CPAP treatment.' The review suggests that OSA-mediated brain hemodynamics and brain atrophy are concomitant with cognitive dysfunction. It is concluded that OSA results in cerebral hemodynamic instability, hypoxia, and sleep fragmentation which appear to be the major contributing factors to the brain structural changes and cognitive deficits. Furthermore, the reviewed studies indicate that CPAP treatment may partially reverse or diminish the adverse effects of OSA on the brain structure and function. Additional investigations are urgently needed to elucidate the underlying mechanisms of the effects of OSA on the brain and the efficacy of CPAP therapy for brain protection. [ABSTRACT FROM AUTHOR]

Anger management styles (i.e., anger-in and anger-out) characterize a person's typical response to anger. Anger-in, the suppression of anger, and anger-out, the outward expression of anger, have been associated with increased acute and chronic pain. Previous research suggests that anger-in is related to pain because of its shared variance with negative affect; anger-out is believed to be related to pain because of a disruption of endogenous opioid systems. It is currently unknown whether anger management styles promote pain by facilitating central sensitization or spinal nociception. This study assessed the relationship between anger management styles and markers of central sensitization (i.e., temporal summation of pain [ TS-pain] and nociception flexion reflex [ TS- NFR]), spinal nociception (nociception flexion reflex [ NFR] threshold), and measures of pain experience. One hundred nine healthy pain-free individuals completed the study. A bootstrapped mediation analysis was conducted to test whether negative affect mediated relationships with anger-in. Results suggested that anger-in and anger-out were associated with lower NFR thresholds (facilitated spinal nociception), but no other outcome. Negative affect did not mediate either of these relationships. These results suggest that anger management styles may amplify spinal nociceptive processes in healthy humans without altering central sensitization. [ABSTRACT FROM AUTHOR]

Stereotypic behaviours are commonly observed in captive animals and are usually interpreted as a sign of poor welfare. Stereotypies have also been linked with brain abnormalities. However, stereotypies are a heterogeneous class of behaviours and mounting evidence indicates that different stereotypies can have different causes, and can be linked to different affective states. As a consequence, the implications of a specific stereotypy in a specific species cannot be safely inferred from evidence on other stereotypies or species. Here we review what is known about pacing behaviour in laboratory rhesus macaques, a common stereotypy in this species. Our review highlights the current lack of understanding of the causal factors underlying pacing behaviour. According to current knowledge, the welfare of pacing macaques could be either better, worse or equivalent to that of non-pacing individuals. It is also unclear whether pacing results from brain abnormalities. Since rhesus macaques are widely used as a model of healthy humans in neuroscience research, determining if pacing behaviour reflects an abnormal brain and/or poor welfare is urgent. [ABSTRACT FROM AUTHOR]

Cannulation implantation into the cisterna magna is an important procedure in cerebrospinal fluid (CSF) sampling and intracranial pressure (ICP) monitoring. The disadvantages of existing techniques include the risk of brain damage, compromised muscle mobility, and the complexity of the procedures. In the present study, the authors describe a modified, simple, and reliable procedure for long-term cannulation implantation into the cisterna magna in rats. The device consists of four parts: the puncture segment, the connection segment, the fixing segment, and the external segment. Intraoperative ICP monitoring and post-operative computed tomography (CT) scans were performed, which confirmed the accuracy and safety of this method. There were no limitations on the daily activities of the rats when long-term drainage was carried out for 1 week. This new technique offers an improved method of cannulation and will be a potentially useful method for CSF sampling and ICP monitoring in neuroscience research., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2023 Hao, Zhang, Chen and Mo.)

Established in 2009, the US Presidential Commission for the Study of Bioethical Issues (Bioethics Commission) advises the President on complex topics in bioethics that arise from advances in medicine, science and technology. The Bioethics Commission repeatedly addresses certain core ethical issues in its analyses, such as the concept of vulnerability and appropriate protections for potentially vulnerable research participants. The Bioethics Commission has addressed vulnerability in several contexts, including paediatric research, multinational research and neuroscience research. In this article, we summarise the Bioethics Commission's analyses and recommendations concerning vulnerability and identify some ethical commonalities across contexts. Through its work on the concept of vulnerability, the Bioethics Commission has sought to clarify long-standing ethical dilemmas and move the conversation forward in support of ethical and scientific progress. [ABSTRACT FROM AUTHOR]

Biobanking of the brain and other central nervous system materials, ie, brain banking (BB), provides an important research tool for understanding the causes of neurodegenerative and psychiatric diseases. Particularly with aging societies, there is an increasing need for molecular neuropathological research in this field. While there is an extensive debate on biobanking in general, the specific challenges that the procurement, processing, and storage of postmortem human brain tissue, and especially whole brains, raise are hardly ever considered systematically. This paper analyzes the peculiarities that make BB a distinct type of biobanking by combining the perspectives of neuropathology, medical informatics, and medical ethics. While ethical, practical, and data-management issues are often dealt with separately and the focus of such research is on only specific aspects of BB, this paper aims at an integrated analysis of the whole process. Six crucial steps in the BB workflow are analyzed: a) donor recruitment, b) follow-up during the donor's lifetime, c) postmortem brain donation, d) neuropathological diagnosis, e) research with brain tissue, and f) the provision of brain material to third parties. A comprehensive understanding of the challenges that BB raises is vital for making this practice more effective but also to counteract the current decline in brain-donation rates. [ABSTRACT FROM AUTHOR]

Advances in neuroscience related to developmental disorders could substantially impact individuals with disabilities and the field of special education. However, several challenges impede the current translation of neuroscience research for special education practice, such as misinterpretations of neuroscience findings. An investigation of translational research in medicine and social sciences revealed a common conceptual framework founded by the National Institutes of Health (NIH). Using this model as a guide, the authors introduce a new framework, the Neuroeducation Translational (NET) Research Model, to scaffold neuroscience research from the laboratory to special education practice in four phases. Potential benefits to developing a framework for neuroeducation include improved outcomes for individuals with disabilities and knowledge sharing across disciplines. [ABSTRACT FROM AUTHOR]

Neuroscience research in India has been mapped for the years 1992-2005 using Neuroscience Citation Index (NSCI) and PubMed. A total of 18,138 papers, with 1.31 times citations, have been published in 1975 journals from 47 different countries. Fourteen out of the top 18 productive journals are from India; of which only 6 have Impact Factor 2009 (IF-2009). Interestingly, only 4 out of the 25 highly cited journals are Indian. And 322 papers have appeared in 28 Letters and Communication journals. The dataset has been found to be a perfect fit for the Bradford law of scattering – both verbal and graphical formulations of the law. About 20% of the papers are published in journals which are having no IF, and 61% papers in journals having IF < 3. However, only 128 papers are published in journals having IF > 10, out of which 15 papers have not been cited at all. Papers have authors from 1401 Indian institutions; but only 9.2% institutions contribute 80.1% papers. Also, papers are authored by 1 to 27 authors; multi-author papers are better cited. Collaborations have been studied for papers indexed in NSCI only and not PubMed. Indian authors have international collaborations in only 12% papers indexed in NSCI with authors from 75 different countries – predominantly G7 nations and the internationalization index is 16.14. More than 70% papers have not been cited at all and those published in 1998 have been better cited. Papers drew maximum citations 4-5 years after publication. Papers having international collaborations are cited more often. [ABSTRACT FROM AUTHOR]

Issues of disclosure arise in neuroscientific research during the informed consent process, whenever incidental findings are identified, and when study results are generated. The possibility of disclosure of incidental findings and/or research results may raise informational expectations on the part of subjects and may alter a study's risk:benefit ratio. We recommend that the informed consent process address this potential consequence of research participation, and specify the conditions under which particular types of information will be offered, the conditions under which information may not be disclosed, and any provisions for helping subjects make sense of the information to be disclosed. [ABSTRACT FROM AUTHOR]

The search for traces of past and present life is a complex and multidisciplinary research activity involving several scientific heritages and a specific industrial ability for planetary exploration. Laben was established in 1958 to design and manufacture electronic instruments for research in nuclear physics. In the mid 2004 the company was merged with Alenia Spazio. It is now part of Alcatel Alenia Space, a French Italian joint venture. Alcatel Alenia Space Italia SpA is a Finmeccanica Company. Currently the plant of Vimodrone provides a wide heritage in life science oriented to space application. The experience in Space Life Science is consolidated in the following research areas: Next Biotechnology studies and development: The biological features of this heritage is at disposal for the exobiology multi science. The involvement of industries, from the beginning of the exobiology projects, allows a cost effective technologies closed loop development between Research Centres, Principal Investigators and industry. [ABSTRACT FROM AUTHOR]

The integration of information from neuroscience with the practice of psychotherapy presents with numerous challenges. However, neuroscience research can guide practitioners in the purposeful use of the therapeutic relationship to enhance clinical outcomes. This article reviews such research pertinent to mental health and psychotherapy, and presents an a-theoretical model of intervention, guided by this information that can be incorporated into various therapeutic orientations. [ABSTRACT FROM AUTHOR]

Electroencephalography (EEG) and deep brain stimulation (DBS), as specific instrument and tool, respectively, for reading and changing the electrical activities of the human brain, are milestones in the history of neuroscience and brain research. Although scientists have gone very far in exploring the brain, the mechanisms of many neurological diseases and therapies are not clear yet. Therefore, an implanted rechargeable EEG device, adding the recording function to conventional DBS to make it not only a therapy device but a scientific research tool has been developed. The EEG performance of the device is good compared with the SynAmps2 of NeuroScan. Radio‐frequency (RF) communication at 403 MHz is used for data transmission, which has a high speed and long transmission distance and enables mass quantity data transmission. A rechargeable battery is used for power supply, making the system life longer and lowering the requirement of low‐power design. This device is a good platform for neuroscience research by being implanted in animal models of different nervous system disorders or patients with diseases such as Parkinson's disease (PD). The recorded data will help to better understand the brain and the mechanisms of brain disorders and also help to optimise clinical therapy. [ABSTRACT FROM AUTHOR]

This study is aimed at evaluating the outcomes of mind-body transformation therapy (MBT-T), previously known as the creative psychosocial genomic healing experience© (CPGHE). The intervention was aimed at reducing the perceived level of stress in two non-clinical groups of students with different educational levels and different expertise in the domain of well-being. Whereas participants from the first group were first-year university students, participants from the second group were students attending a post-graduate program in psychotherapy. All participants (n = 159) were exposed to a single session of MBT-T, each group in a separate session. The results of two paired-samples t-tests, conducted separately on the two samples, showed that there was a statistically significant reduction in the participants' perceived level of stress between pre- and post-intervention states in both samples (t88 = 5.39, p < 0.001; t53 = 4.56, p < 0.001 respectively). The results, therefore, showed that a single session of MBT-T was beneficial in reducing the perceived level of stress in both first-year university students and students attending a post-graduate program in psychotherapy, regardless of educational level and expertise in the domain of well-being. [ABSTRACT FROM AUTHOR]

Summary: Although healthy volunteers often serve as controls or primary participants in neuroscience research, they are usually less rigorously screened than patients, which can have far‐reaching implications for interpretation of study results. Although this issue has long been recognised, it is rarely discussed in the research literature. This article examines how the rigorous screening and characterisation of healthy volunteers is key for quality research. [ABSTRACT FROM AUTHOR]

Background and Purpose: Nowadays, the focus of genetic, neurobiological, neuropsychological and psychosocial research is on a more accurate discovery of the etiology of mental illnesses, especially with regard to the role and complex interactions of certain risk factors. It is increasingly challenging to interpret the results of different aspects and methodologies in a coherent theoretical framework, as this can only lead to a more accurate understanding of the complexity and mechanism of the psychiatric disorders. The main aim of this paper to overview recent studies on etiological background of mental disorders and to present the most important aspects of the Research Domain Criteria (RDoC) system., Methods: Review of reports from comprehensive studies published in the most important psychiatric journals over the past five years summarizing new findings on the etio-logy of mental disorders., Results: Although current classifications indicate that mental disorders are strictly distinct diagnostic categories, new findings suggest that these marked differences in symptomatic, genetic, and neurobiological backgrounds are not detectable, as many mental disorders have been identified as having common molecular genetic risk factors, which may indicate common neurobiological pathomechanisms., Conclusion: Research results support the need for a rethinking of psychiatric nosology on an etiological basis and represent an important step forward in the more accurate exploration of the neurobiological background factors of mental disorders and thus in the development of more targeted therapeutic approaches. The development of the RDoC system can be a great help in this, as this dimensional approach offers the possibility of integrating the - often diffuse or even contradictory - neuroscientific research findings into a unified theoretical framework for the etiology, nosology and treatment of mental disorders.

Although healthy volunteers often serve as controls or primary participants in neuroscience research, they are usually less rigorously screened than patients, which can have far-reaching implications for interpretation of study results. Although this issue has long been recognised, it is rarely discussed in the research literature. This article examines how the rigorous screening and characterisation of healthy volunteers is key for quality research. [ABSTRACT FROM AUTHOR]