Search

Your search keyword '"Mroz, Thomas E."' showing total 556 results
Start Over Author "Mroz, Thomas E." Publication Type Academic Journals
556 results on '"Mroz, Thomas E."'

4. Bony ingrowth potential of 3D-printed porous titanium alloy: a direct comparison of interbody cage materials in an in vivo ovine lumbar fusion model

Author

McGilvray, Kirk C, Easley, Jeremiah, Seim, Howard B, Regan, Daniel, Berven, Sigurd H, Hsu, Wellington K, Mroz, Thomas E, and Puttlitz, Christian M

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Bioengineering, Alloys, Animals, Benzophenones, Biomechanical Phenomena, Bone-Anchored Prosthesis, Ketones, Lumbar Vertebrae, Osseointegration, Polyethylene Glycols, Polymers, Printing, Three-Dimensional, Prosthesis Design, Range of Motion, Articular, Sheep, Spinal Fusion, Titanium, X-Ray Microtomography, 3D porous titanium, Interbody cage, Ovine, PEEK, Spine, Spine fusion, Neurosciences, Orthopedics, Clinical sciences, Allied health and rehabilitation science
Abstract

Background contextThere is significant variability in the materials commonly used for interbody cages in spine surgery. It is theorized that three-dimensional (3D)-printed interbody cages using porous titanium material can provide more consistent bone ingrowth and biological fixation.PurposeThe purpose of this study was to provide an evidence-based approach to decision-making regarding interbody materials for spinal fusion.Study designA comparative animal study was performed.MethodsA skeletally mature ovine lumbar fusion model was used for this study. Interbody fusions were performed at L2-L3 and L4-L5 in 27 mature sheep using three different interbody cages (ie, polyetheretherketone [PEEK], plasma sprayed porous titanium-coated PEEK [PSP], and 3D-printed porous titanium alloy cage [PTA]). Non-destructive kinematic testing was performed in the three primary directions of motion. The specimens were then analyzed using micro-computed tomography (µ-CT); quantitative measures of the bony fusion were performed. Histomorphometric analyses were also performed in the sagittal plane through the interbody device. Outcome parameters were compared between cage designs and time points.ResultsFlexion-extension range of motion (ROM) was statistically reduced for the PTA group compared with the PEEK cages at 16 weeks (p-value=.02). Only the PTA cages demonstrated a statistically significant decrease in ROM and increase in stiffness across all three loading directions between the 8-week and 16-week sacrifice time points (p-value≤.01). Micro-CT data demonstrated significantly greater total bone volume within the graft window for the PTA cages at both 8 weeks and 16 weeks compared with the PEEK cages (p-value

Published
2018

5. Impact of Baseline Magnetic Resonance Imaging on Neurologic, Functional, and Safety Outcomes in Patients With Acute Traumatic Spinal Cord Injury.

Author

Kurpad, Shekar, Martin, Allan R, Tetreault, Lindsay A, Fischer, Dena J, Skelly, Andrea C, Mikulis, David, Flanders, Adam, Aarabi, Bizhan, Mroz, Thomas E, Tsai, Eve C, and Fehlings, Michael G

Subjects
functional outcomes, magnetic resonance imaging, neurologic outcomes, risk factors, spinal cord injury, Neurosciences, Traumatic Head and Spine Injury, Spinal Cord Injury, Patient Safety, Physical Injury - Accidents and Adverse Effects, Clinical Research, Neurodegenerative, Biomedical Imaging, Injuries and accidents, Neurological
Abstract

Study designSystematic review.ObjectiveTo perform a systematic review to evaluate the utility of magnetic resonance imaging (MRI) in patients with acute spinal cord injury (SCI).MethodsAn electronic search of Medline, EMBASE, the Cochrane Collaboration Library, and Google Scholar was conducted for literature published through May 12, 2015, to answer key questions associated with the use of MRI in patients with acute SCI.ResultsThe literature search yielded 796 potentially relevant citations, 8 of which were included in this review. One study used MRI in a protocol to decide on early surgical decompression. The MRI-protocol group showed improved outcomes; however, the quality of evidence was deemed very low due to selection bias. Seven studies reported MRI predictors of neurologic or functional outcomes. There was moderate-quality evidence that longer intramedullary hemorrhage (2 studies) and low-quality evidence that smaller spinal canal diameter at the location of maximal spinal cord compression and the presence of cord swelling are associated with poor neurologic recovery. There was moderate-quality evidence that clinical outcomes are not predicted by SCI lesion length and the presence of cord edema.ConclusionsCertain MRI characteristics appear to be predictive of outcomes in acute SCI, including length of intramedullary hemorrhage (moderate-quality evidence), canal diameter at maximal spinal cord compression (low-quality evidence), and spinal cord swelling (low-quality evidence). Other imaging features were either inconsistently (presence of hemorrhage, maximal canal compromise, and edema length) or not associated with outcomes. The paucity of literature highlights the need for well-designed prospective studies.

Published
2017

8. Hypoglossal Nerve Palsy After Cervical Spine Surgery

Author

Ames, Christopher P, Clark, Aaron J, Kanter, Adam S, Arnold, Paul M, Fehlings, Michael G, Mroz, Thomas E, and Riew, K Daniel

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Neurosciences, Traumatic Head and Spine Injury, Physical Injury - Accidents and Adverse Effects, Neurodegenerative, Patient Safety, Injuries and accidents, cervical spine, complications, hypoglossal palsy, glossopharyngeal palsy, retrospective, Clinical sciences
Abstract

Study designMulti-institutional retrospective study.ObjectiveThe goal of the current study is to quantify the incidence of 2 extremely rare complications of cervical spine surgery; hypoglossal and glossopharyngeal nerve palsies.MethodsA total of 8887 patients who underwent cervical spine surgery from 2005 to 2011 were included in the study from 21 institutions.ResultsNo glossopharyngeal nerve injuries were reported. One hypoglossal nerve injury was reported after a C3-7 laminectomy (0.01%). This deficit resolved with conservative management. The rate by institution ranged from 0% to 1.28%. Although not directly injured by the surgical procedure, the transient nerve injury might have been related to patient positioning as has been described previously in the literature.ConclusionsHypoglossal nerve injury during cervical spine surgery is an extremely rare complication. Institutional rates may vary. Care should be taken during posterior cervical surgery to avoid hyperflexion of the neck and endotracheal tube malposition.

Published
2017

Catalog

Books, media, physical & digital resources
See catalog results