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Your search keyword '"Mokhtari, K."' showing total 441 results
Start Over Author "Mokhtari, K." Publication Type Academic Journals
441 results on '"Mokhtari, K."'

1. Prognosis of glioblastoma patients improves significantly over time interrogating historical controls

Author

Thomas-Joulié, A., Tran, S., El Houari, L., Seyve, A., Bielle, F., Birzu, C., Lozano-Sanchez, F., Mokhtari, K., Giry, M., Marie, Y., Laigle-Donadey, F., Dehais, C., Houillier, C., Psimaras, D., Alentorn, A., Laurenge, A., Touat, M., Sanson, M., Hoang-Xuan, K., Kas, A., Rozenblum, L., Habert, M.-O., Nichelli, L., Leclercq, D., Galanaud, D., Jacob, J., Karachi, C., Capelle, L., Carpentier, A., Mathon, B., Belin, L., and Idbaih, A.

Published
2024
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6. Guidelines, “minimal requirements” and standard of care in glioblastoma around the Mediterranean Area: A report from the AROME (Association of Radiotherapy and Oncology of the Mediterranean arEa) Neuro-Oncology working party

Author

Belkacemi, Y., Bolle, S., Bourdeaut, F., Collin, P., Cornu, P., Delatre, J.-Y., Dhermain, F., Doz, F., Habrand, J.-L., Hoang-Xuan, K., Idbaih, A., Mammar, H., Martin-Duverneuil, N., Mokhtari, K., Roujeau, T., Acharqui, A., Atit Benali, S., Bakhti, S., Bena, F., Bendjaafar, N., Benider, A., Bouaouina, N., Bounedjar, A., Boussen, H., Bouyoucef, K., Bouzid, K., Chougai, Z., Daoud, J., Errihani, H., Essoudaigui, F., Gachi, F., Harif, M., Hilmani, S., Hsissen, L., Idali, B., Karkouri, M., Kerboua, E., Ouahabi, A., Sahraoui, S., Sadki, O., Sami, A., Samlali, R, and Terkmani, F.

Published
2016
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9. Differences in the Metacognitive Awareness of Reading Strategies among Native and Non-Native Readers.

Author

Sheorey, R. and Mokhtari, K.

Abstract

Examines the differences in the reported use of reading strategies of native and non-native English speakers when reading academic materials. Participants were native English speaking and English-as-a-Second-Language college students who completed a survey of reading strategies aimed at discerning the strategies readers report using when coping with academic reading tasks. (Author/VWL)

Published
2001

21. Effects of Achillea tenuifolia Lam. hydro-alcoholic extract on anxiety-like behavior and reproductive parameters in rat model of chronic restraint stress.

Author

Bagheri, Y, Fathi, E, Maghoul, A, Moshtagh, S, Mokhtari, K, Abdollahpour, A, Montazersaheb, S, and Bagheri, A

Subjects
PSYCHOLOGICAL stress, IMMOBILIZATION stress, ANIMAL disease models, ANIMAL sexual behavior, ANXIETY, LABORATORY rats, SEMEN analysis, MALE reproductive organs
Abstract

Introduction: Achillea tenuifolia Lam (AT) has several biological activities and medicinal properties. In this study, we elucidated the impact of the AT on anxiety-related behaviors, reproductive parameters, antioxidant capacity in male rats subjected to chronic restraint stress (CRS). Methods: 35 Wistar rats were divided into five groups: control, CRS-control (received normal saline) and three CRS-treated groups received AT extract (100, 150, and 200 mg/kg body weight) for 21 consequences days. To induce CRS rats, the rats were immobilized for 21 days and received the extract orally. On the last day of treatment, anxiety-related behaviors were assessed through the sucrose preference test (SPT) as well as elevated plus maze (EPM) tests. Corticosterone, luteinizing hormone (LH), and follicle-stimulating hormone (FSH), testosterone levels were evaluated to determine reproductive capacity. Sperm parameters including the total count, motility, and viability were also analyzed. Weight of body, testis and seminal vesicles was measured as well. Results: The findings revealed that 100, 150, and 200 mg/kg of AT extract had anxiolytic effects in CRS rats, as confirmed by the EPM test and SPT. In addition, AT extract could improve fertile capacity and sperm quality to varying degrees. The level of corticosterone had decreased, whereas the level of LH, FSH and testosterone had increased in CRS-treated rats. Moreover, the reduced level of MDA coincided with an increased rate of antioxidant capacity. Our findings suggest that AT extract could alleviate stress-induced dysfunctions. Conclusion: Overall, these observations would infer that AT extract could improve fertility capacity and behavioral impairment in the stress conditions. Assumption pathway describing the probability underlying mechanism of CRS-induced anxiety and reproductive toxicity and protective effect of AT. [ABSTRACT FROM AUTHOR]

Published
2021
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45. TERT promoter mutations in gliomas, genetic associations and clinico-pathological correlations.

Author

Labussière, M, Gleize, V, Giry, M, Mangesius, S, Bruno, A, Mokhtari, K, Di Stefano, A L, Boisselier, B, Paterra, R, Finocchiaro, G, Marie, Y, Rahimian, A, Houlston, R S, Hoang-Xuan, K, Idbaih, A, Delattre, J-Y, and Sanson, M

Subjects
TELOMERASE reverse transcriptase, GLIOMAS, GENETIC mutation, MOLECULAR structure of transcription factors, DNA mutational analysis, GENETIC polymorphisms, GENOTYPES, GENETICS
Abstract

Background:The role of telomerase reverse transcriptase (TERT) in gliomagenesis has been recently further strengthened by the frequent occurrence of TERT promoter mutations (TERTp-mut) in gliomas and evidence that the TERT SNP genetic rs2736100 influences glioma risk. TERTp-mut creates a binding site for Ets/TCF transcription factors, whereas the common rs2853669 polymorphism disrupts another Ets/TCF site on TERT promoter.Methods:We sequenced for TERTp-mut in 807 glioma DNAs and in 235 blood DNAs and analysed TERT expression by RT-PCR in 151 samples. TERTp-mut status and TERTp polymorphism rs2853669 were correlated with histology, genomic profile, TERT mRNA expression, clinical outcome and rs2736100 genotype.Results:TERTp-mut identified in 60.8% of gliomas (491 out of 807) was globally associated with poorer outcome (Hazard ratio (HR)=1.50). We defined, based on TERTp-mut and IDH mutation status, four prognostic groups: (1) TERTp-mut and IDH-mut associated with 1p19q codeletion, overall survival (OS)>17 years; (2) TERTp-wt and IDH-mut, associated with TP53 mutation, OS=97.5 months; (3) TERTp-wt and IDH-wt, with no specific association, OS=31.6 months; (4) TERTp-mut and IDH-wt, associated with EGFR amplification, OS=15.4 months. TERTp-mut was associated with higher TERT mRNA expression, whereas the rs2853669 variant was associated with lower TERT mRNA expression. The mutation of CIC (a repressor of ETV1-5 belonging to the Ets/TCF family) was also associated with TERT mRNA upregulation.Conclusions:In addition to IDH mutation status, defining the TERTp-mut status of glial tumours should afford enhanced prognostic stratification of patients with glioma. We also show that TERTp-mut, rs2853669 variant and CIC mutation influence Tert expression. This effect could be mediated by Ets/TCF transcription factors. [ABSTRACT FROM AUTHOR]

Published
2014
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50. La fréquence des mutations de BRAF est élevée dans les histiocytoses de Langerhans et d’Erdheim-Chester, mais nulle dans les autres histiocytoses

Author

Charlotte, F., Haroche, J., Arnaud, L., Von Deimling, A., Hélias-Rodzewicz, Z., Hervier, B., Cohen, F., Launay, D., Lesot, A., Mokhtari, K., Canioni, D., Galmiche, L., Rose, C., Schmalzing, M., Croockewit, S., Kambouchner, M., Copin, M.-C., Fraitag, S., Sahm, F., Brousse, N., Amoura, Z., Donadieu, J., and Emile, J.-F.

Published
2012
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