1. A novel risk score for venous thromboembolism in lung cancer patients: a retrospective cohort study [version 1; peer review: awaiting peer review]
- Author
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Houda Rouis, Chirine Moussa, Islem mejri, Soumaya Debbiche, Nourchene Khalfallah, Lenda Ben Hmida, Amel Khattab, Zied Moetamri, Mohamed Lamine Megdiche, Hela Kamoun, and Sonia Maâlej
- Subjects
Research Article ,Articles ,Lung cancer ,Venous thromboembolism ,risk score - Abstract
Background: Venous thromboembolism (VTE) is a common and potentially fatal complication in patients with lung cancer. This study aimed to develop and validate a risk score for early prediction of VTE in these patients. Methods: Four hundred and one patients with lung cancer from three pulmonology departments hospitalized between January 2011 and December 2021 were retrospectively assessed. The population was divided into two groups: a Development Group (182 patients) and a validation group (199 patients). In the development group, the risk score system was developed, via univariate and multivariate analyses, based on demographic and clinicopathological variables; it was then validated in the validation group. Results: The incidence of VTE was 26.8% in the development group. It was 25.8%, and 27.6% in the internal and external validation groups, respectively. Hemoglobin level Conclusions: This risk score requires prospective validation studies on a nationwide scale in order to use it as a valid tool for the prevention of VTE in lung cancer.
- Published
- 2023
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