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Abstract Homalopsid snakes of the genus Myrrophis include only two species distributed in southern China and northern Vietnam. Here, we describe a third species from southern Vietnam based on morphological data and nucleotide sequences from the mitochondrial gene cyt b. Myrrophis dakkrongensis sp. nov. is diagnosed by the following morphological characters: Medium-sized mud snake (largest total length 452 mm); internasal single and distinctly separated from loreals; dorsal scales smooth, in 23 rows at midbody, reduced to 19 or 20 rows before vent; ventrals 133–138; subcaudals 34–42, paired; cloacal plate divided; supralabials 8, fourth entering orbit; second pair of chin-shields small and oblique; maxillary teeth 17 or 18; gland-like tubercles present in the cloacal region; hemipenis short, forked and spinose, reaching 7th subcaudal; dorsum dark brown to black; and a white or yellow to orange lateroventral stripe present. The new species differs from its congeners by an uncorrected p distance in cyt b sequences of at least 10.5%.

Throughout all the countries in the world, including Vietnam, nations with well-established mining industries have undertaken extensive research on the stability of rock masses when constructing underground tunnels in varied geological conditions. The present study aims to provide a comprehensive overview of the risk assessment related to rock masses during the construction of pit lines in mining operations. Consequently, the standing time of unsupported tunnels is assessed based on different values of the strength index and deformation characteristics of the rock mass. The objective was to perform both experimental and theoretical investigations to analyse how the stand-up time of rock masses surrounding a tunnel affects the unsupported span. The analyses were based on considering the rock parameters, including strain modulus; geological strength index; and allowable displacement values, and consideration of hereditary creep properties. By examining tunnels excavated in rock strata, it was concluded that varying geological strength index values resulted in distinct creep behaviour in the surrounding rock masses. Thus, it was reasonable to compute the unsupported span and stand-up time of tunnels. The research revealed that permissible displacements are significantly influenced by the types of rock materials surrounding the tunnel structure. Recognising the significance of time, the authors introduce a more practical interpretation and evaluation of the stability of rock masses, thus enhancing the precision of commonly available models.

Introduction: Aflatoxins B1 are among the most common poisonous mycotoxins produced by certain fungi that harm animals and crops. Mycotoxins can cause a variety of adverse health effects and pose a serious health threat to humans. The Maximum Residue Limits of aflatoxin B1 in processed cereals and ingredients are 2 parts per billion (ppb) and 5 ppb, respectively. Objectives: To evaluate the status of aflatoxin B 1 contamination in rice, corn and staple food produced in Ha Giang province compared with the maximum permitted levels. Methods: A total of 210 rice and maize samples were analyzed to quantify the level of aflatoxin B1. Analysis of mycotoxins was conducted by High Performance Liquid Chromatography using a fluorescence detector. Results: It was found that rice, rice products, maize, and maize products had a mean aflatoxin B1 content of 1.79 ppb, 2.55 ppb, 2.19 ppb, and 6.35 ppb, respectively. The results also showed that 71.9% of samples were contaminated with mycotoxins, and 14.28% of samples exceeded the maximum allowable limit. Conclusion: The concentration of aflatoxin B1 in 14.28% of the samples are over permissible limits by nationwide regulations.

Introduction: In the hyperbaric pressure environment the partial pressure of each gas component increases, which increases oxygen partial pressure. This causes the generation of free radicals and oxidative stress. Objective: To determine the effects of hyperbaric pressure on the oxidative stress status in healthy subjects. Methods: 29 healthy men performed standardized hyperbaric chamber dive to a depth of 30 meters of water (msw) for 30 minutes. Blood samples were collected before compression, immediately after decompression and 1 hour after decompression. The levels of Malondialdehyde, Catalase and Superoxide Dismutase were measured in blood samples. Results: Malondialdehyde activity increased immediately after decompression and recovered at 1 hour after decompression. Superoxide Dismutase enzyme activity decreased immediately after decompression as well as 1 hour after decompression. Catalase enzyme activity increased immediately after decompression, which was significant at 1 hour after decompression. Conclusion: Changes in the biologic markers Malondialdehyde, Catalase and Superoxide Dismutase suggest the appearance of oxidative stress under the influence of a hyperbaric pressure environment.

IntroductionIt is widely known that motor learning changes the excitability of the primary motor cortex. More recently, it has been shown that the primary somatosensory cortex (S1) also plays an important role in motor learning, but the details have not been fully examined. Therefore, we investigated how motor skill training affects somatosensory evoked potential (SEP) in 30 neurologically healthy subjects.MethodsSEP N20/P25_component and N20/P25 SEP paired-pulse depression (SEP-PPD) were assessed before and immediately after complex or simple visuomotor tasks.ResultsMotor learning was induced more efficiently by the complex visuomotor task than by the simple visuomotor task. Both the N20/P25 SEP amplitude and N20/P25 SEP-PPD increased significantly immediately after the complex visuomotor task, but not after the simple visuomotor task. Furthermore, the altered N20/P25 SEP amplitude was associated with an increase in motor learning efficiency.ConclusionThese results suggest that motor learning modulated primary somatosensory cortex excitability.

In this study, we employed synthesized titanium oxide/zirconium oxide (TiO2/ZrO2) nanoparticles as activated catalysts to enhance the ozonation process during hydroxyl radical (OH°) generation using atrazine (ATZ) as a pollutant. The TiO2/ZrO2 nanoparticles were synthesized using the coprecipitation digestion method and were characterized using scanning and transmission electron microscopy, X-ray diffraction, Brunauer–Emmett–Teller theory, and energy dispersive X-ray spectroscopy. The experiments were conducted under different initial pH conditions (3, 7, and 10), with an initial ATZ concentration of 4.64 × 10−6 M, initial TiO2/ZrO2 nanocatalyst concentrations of 100, 200, and 300 ppm, and initial ozone (O3) concentrations of 1.35 × 10−4, 1.55 × 10−4, and 2.27 × 10−4 M, respectively. The key operational parameters were optimized, and the optimal OH° results were obtained at pH 10, 200 ppm TiO2/ZrO2 concentration, 4.64 × 10−6 M ATZ concentration, and 1.55 × 10−4 M O3 concentration. The potential of TiO2/ZrO2 nanoparticles to enhance OH° generation during catalytic ozonation was demonstrated. The catalytic ozonation mechanism using TiO2/ZrO2 nanoparticles was governed by the optimal formation of OH° radicals at about 1 × 10−11 mol/L and an excellent nanocatalytic activity with an Rct value of 2.83 × 10−8. [ABSTRACT FROM AUTHOR]

Background: In pregnant women with gestational diabetes mellitus (GDM), insulin resistance (IR) increases the risk of developing manifest type 2 diabetes mellitus and is associated with complications in both mother and fetus. Objectives: This research aimed to evaluate the associations between IR evaluated by 3 indices (namely updated homeostasis model assessment model (HOMA2), QUICKI, and McAuley’s index) and the diabetes risk factors and the fetal growth indices in Vietnamese women with GDM. Methods: A cross-sectional descriptive study was conducted on 370 women with GDM and 40 healthy pregnant women from January 2015 to May 2019. IR was calculated by HOMA2 (HOMA2-IR), QUICKI, and McAuley’s index. Fetal anthropometric measurements were assessed via ultrasound which was performed and interpreted by ultrasound experts. Results: In the simple regression analysis, McAuley’s index illustrated had statistically significant correlations to the highest number of risk factors of diabetes mellitus compared with HOMA2-IR and QUICKI indices. Moreover, McAuley’s index correlated statistically significantly to the highest number of fetal ultrasound measurements factors such as including biparietal diameter (BPD) ( r = −0.271, P

We report the southernmost record of the Rhinoceros Snake, Gonyosoma boulengeri (Mocquard, 1897) from Phu Yen Province, southern Vietnam, based on a single specimen collected from forest in the Ca Range. This record extends the distribution of G. boulengeri approximately 600 km south of previous records in Vietnam (Quang Binh Province, central Vietnam). A detailed description of a hemipenis is also provided for the first time.

The treatment of nutrients and organic contaminants in wastewater using microalgae has drawn significant interest thanks to its advantages of environmental friendliness, low cost, CO2 emission reduction, and recycling of valuable biomass. Among other algae species, Chlorella sp. showed good vitality, simplicity in cultivation, and high nutrient accumulation in harsh conditions of wastewater. In this study, Chlorella vulgaris was inoculated in a membrane photobioreactor (MPBR) with piggery digestate to investigate the C. vulgaris growth rate and the removal efficiency of nutrients and chemical oxygen demand (COD). The results indicated that the cultivation of C. vulgaris in an MPBR system exhibited continuous and simultaneous removal of NH4+, PO43−, and COD from two-fold diluted piggery wastewater. Both the algae growth rate and nutrient removal depended on the liquid hydraulic retention time in the MPBR. The highest removal efficiency of NH4+ (74.55%), PO43− (70.20%), and COD (65.85%) was obtained in the longest HRT of 5 days with the highest microalgae biomass concentration of around 1.1 g/L. The algae washout phenomenon was negligible in the continuous cultivation in the MPBR system. Compared to the cultivation in batch mode, the MPBR could achieve a similar algae growth rate and treatment efficiency with a much shorter hydraulic retention time.

Future climate projections and their uncertainties affect many aspects of the world, so reliable assessments are essential for policymakers who need to prepare mitigation measures in the context of climate change. In this study, we examined the projected future climate and estimated uncertainty for South Korea using results from the global climate model (GCM), updated from the sixth phase of the coupled model intercomparison project (CMIP6); we then compared the differences in outcome between the fifth and sixth phases of the CMIP (CMIP5 and CMIP6). Future projections were estimated as the averaged climatological mean (denoted as CM¯) for the four proposed hydrological indicators. Model uncertainty (UEMI) and stochastic uncertainty (USTO) were quantified as the range of ensembles of the climatological mean, while the emission uncertainty (UEMI) was estimated as the difference between the CM¯ values of two emission scenarios. The following are the key findings of our study: (1) using an ensemble of multiple GCMs is recommended over using individual GCMs, and models in CMIP6 performed better for reproducing climate during the control period than models in the CMIP5; (2) the CM¯ values in the CMIP6 increased for future periods, especially toward the end of this century, increasing mean temperature (meanTa) by approximately 5 °C, total precipitation (totPr), and daily maximum precipitation (maxDa) by about 20%, and these values were higher than those of the CMIP5; (3) the UGCM, USTO, and UEMI values increased for future periods in most of the indices; (4) the UGCM (for meanTa, totPr, and maxDa) and USTO (for totPr and maxDa) magnitudes in the CMIP6 were higher than those in the CMIP5, while the UEMI values between the two CMIPs were similar for all of the indices; (5) the UGCM was the major source of the largest uncertainty for meanTa, the USTO had a significant impact on future projections of totPr and maxDa, especially in the summer, and the UEMI became the dominant source of uncertainty for projecting the future meanTa, especially in the period farthest from the present. These results should provide useful information for studies that quantify future climate-induced hydrological impacts.

Throughout all the countries in the world, including Vietnam, nations with well-established mining industries have undertaken extensive research on the stability of rock masses when constructing underground tunnels in varied geological conditions. The present study aims to provide a comprehensive overview of the risk assessment related to rock masses during the construction of pit lines in mining operations. Consequently, the standing time of unsupported tunnels is assessed based on different values of the strength index and deformation characteristics of the rock mass. The objective was to perform both experimental and theoretical investigations to analyse how the stand-up time of rock masses surrounding a tunnel affects the unsupported span. The analyses were based on considering the rock parameters, including strain modulus; geological strength index; and allowable displacement values, and consideration of hereditary creep properties. By examining tunnels excavated in rock strata, it was concluded that varying geological strength index values resulted in distinct creep behaviour in the surrounding rock masses. Thus, it was reasonable to compute the unsupported span and stand-up time of tunnels. The research revealed that permissible displacements are significantly influenced by the types of rock materials surrounding the tunnel structure. Recognising the significance of time, the authors introduce a more practical interpretation and evaluation of the stability of rock masses, thus enhancing the precision of commonly available models. [ABSTRACT FROM AUTHOR]

Salinity is crucial in fish larval rearing. In longfin batfish (Platax teira), little research has been conducted regarding the specific effects of salinity on growth, survival, deformity, and food utilization efficiency. This study aimed to determine the optimal salinity level for larval rearing of the longfin batfish by testing five different salinity levels (10, 15, 20, 25, and 30°). Larvae of 1.5 cm in length and 0.2 g/fish in weight were stocked in cylindrical fiberglass tanks (300 L) at a density of 1 fish/L. The fish were fed to meet their dietary requirement and divided into four daily feedings. Each treatment was replicated three times over a 28-day period of rearing. The results revealed that salinity significantly influenced the growth (length, weight, biomass), and food utilization efficiency of the longfin batfish larvae. Overall, larvae reared at salinity levels of 15-20° exhibited superior performance compared to those exposed to salinity levels of 10, 25, and 30°. However, salinity did not affect the coefficient of variation, survival, and deformity. From these findings, it is recommended to rear longfin batfish larvae at a salinity of 15-20° to achieve optimal growth and food utilization efficiency. This study provides valuable insights for longfin batfish larval rearing guidance, contributing to the aquaculture development of this economically valuable species. [ABSTRACT FROM AUTHOR]

We investigated changes in some laboratory indices and the liver histology of chronic hepatitis patients who were exposed to dioxin. In 2014, we collected liver biopsy samples for histopathological examination from 33 chronic hepatitis patients living around the Da Nang Airbase, which is a dioxin-contaminated area due to the herbicide spraying in Vietnam. Dioxin exposure was measured by its levels in the blood. METAVIR classification was used to clarify the liver fibrosis stage. Laboratory tests included ten biochemical and six hematological indices that were measured in the blood. A regression linear model and binary logistic regression were used for data analysis. The observed alterations in the liver at the histological level mainly comprised hydropic degenerative hepatocytes, lymphocytes and polynuclear leukocytes surrounding the liver cells and granular and lipoic degeneration. In addition, increased TCDD levels were associated with increasing aminotransferase (AST), alanine aminotransferase, protein and total bilirubin levels and liver fibrosis stage. Similarly, increased TEQ-PCDD/Fs levels were associated with higher levels of AST and protein and liver fibrosis stage. In conclusion, dioxin exposure altered the liver histology and increased some biochemical marker indices and the liver fibrosis stage of chronic hepatitis patients living in dioxin-contaminated areas in Da Nang, Vietnam.

A decrease in cortical excitability tends to be easily followed by an increase induced by external stimuli via a mechanism aimed at restoring it; this phenomenon is called “homeostatic plasticity.” In recent years, although intervention methods aimed at promoting motor learning using this phenomenon have been studied, an optimal intervention method has not been established. In the present study, we examined whether subsequent motor learning can be promoted further by a repetitive passive movement, which reduces the excitability of the primary motor cortex (M1) before motor learning tasks. We also examined the relationship between motor learning and the brain-derived neurotrophic factor. Forty healthy subjects (Val/Val genotype, 17 subjects; Met carrier genotype, 23 subjects) participated. Subjects were divided into two groups of 20 individuals each. The first group was assigned to perform the motor learning task after an intervention consisting in the passive adduction–abduction movement of the right index finger at 5 Hz for 10 min (RPM condition), while the second group was assigned to perform the task without the passive movement (control condition). The motor learning task consisted in the visual tracking of the right index finger. The results showed that the corticospinal excitability was transiently reduced after the passive movement in the RPM condition, whereas it was increased to the level detected in the control condition after the motor learning task. Furthermore, the motor learning ability was decreased immediately after the passive movement; however, the motor performance finally improved to the level observed in the control condition. In individuals carrying the Val/Val genotype, higher motor learning was also found to be related to the more remarkable changes in corticospinal excitability caused by the RPM condition. This study revealed that the implementation of a passive movement before a motor learning tasks did not affect M1 excitatory changes and motor learning efficiency; in contrast, in subjects carrying the Val/Val polymorphism, the more significant excitatory changes in the M1 induced by the passive movement and motor learning task led to the improvement of motor learning efficiency. Our results also suggest that homeostatic plasticity occurring in the M1 is involved in this improvement.

Aims. This study is aimed at (1) validating the performance of Oakland and Glasgow-Blatchford (GBS) scores and (2) comparing these scores with the SALGIB score in predicting adverse outcomes of acute lower gastrointestinal bleeding (ALGIB) in a Vietnamese population. Methods. A multicenter cohort study was conducted on ALGIB patients admitted to seven hospitals across Vietnam. The adverse outcomes of ALGIB consisted of blood transfusion; endoscopic, radiologic, or surgical interventions; severe bleeding; and in-hospital death. The Oakland and GBS scores were calculated, and their performance was compared with that of SALGIB, a locally developed prediction score for adverse outcomes of ALGIB in Vietnamese, based on the data at admission. The accuracy of these scores was measured using the area under the receiver operating characteristic curve (AUC) and compared by the chi-squared test. Results. There were 414 patients with a median age of 60 (48–71). The rates of blood transfusion, hemostatic intervention, severe bleeding, and in-hospital death were 26.8%, 15.2%, 16.4, and 1.4%, respectively. The SALGIB score had comparable performance with the Oakland score (AUC: 0.81 and 0.81, respectively; p=0.631) and outperformed the GBS score (AUC: 0.81 and 0.76, respectively; p=0.002) for predicting the presence of any adverse outcomes of ALGIB. All of the three scores had acceptable and comparable performance for in-hospital death but poor performance for hemostatic intervention. The Oakland score had the best performance for predicting severe bleeding. Conclusions. The Oakland and SALGIB scores had excellent and comparable performance and outperformed the GBS score for predicting adverse outcomes of ALGIB in Vietnamese.

This study investigated the torrefaction of de-oiled Jatropha seed residue after a two-stage sequential process consisting of mechanical screw pressing and solvent extraction using n-hexane (denoted as JMS). The optimal torrefaction temperature (Tr) and torrefaction time (tr) were determined in the ranges of 260–300 °C and 10–60 min, respectively, so to achieve a better heating value and satisfactory energy densification (ED) with acceptable mass loss. Thermogravimetric analysis was employed to elucidate the thermal decomposition behaviors of JMS. By comparison with the torrefaction of Jatropha seed residue after mechanical oil extraction by screw pressing only (namely, JMET), the results indicated that the ED of the torrefaction of JMS yielding the torrefied product JMST (two-stage product) was higher than that of the torrefaction of JME giving the torrefied product JMET (single-stage product). Further, it was found that JMET contained some tar, which was attributed to a thermal reaction in the residual oil in JME during torrefaction. The tar/oil content of JMET was about 1.0–1.8 wt.% in the determined optimal conditions. Thus, the enhanced recovery of the residual oil is advantageous not only because it allows obtaining more oil from Jatropha seed residue with a positive net energy gain but also because it prevents the formation of tar in torrefied biomass products.

Designing water infrastructure requires information about the magnitude and frequency of upcoming rainfall. A limited range of data offers just one of many realizations that occurred in the past or will occur in the future; thus, it cannot sufficiently explain climate internal variability (CIV). In this study, future relationships among rainfall intensity (RI), duration, and frequency (called the IDF curve) are established by addressing the CIV and tail characteristics with respect to frequency. Specifically, 100 ensembles of 30-year time series data were created to quantify that uncertainty. Then, the tail characteristics of future extreme rainfall events were investigated to determine whether they will remain similar to those in the present. From the RIs computed for control and future periods under two emission scenarios, following are the key results. Firstly, future RI will increase significantly for most locations, especially near the end of this century. Secondly, the spatial distributions and patterns indicate higher RI in coastal areas and lower RI for the central inland areas of South Korea, and those distributions are similar to those of the climatological mean (CM) and CIV. Thirdly, a straightforward way to reveal whether the tail characteristics of future extreme rainfall events are the same as those in the present is to inspect the slope value for the factor of change (FOC), mFOC. Fourthly, regionalizing with nearby values is very risky when investigating future changes in precipitation frequency estimates. Fifthly, the magnitude of uncertainty is large when the data length is short and gradually decreases as the data length increases for all return periods, but the uncertainty range becomes much greater as the return period becomes large. Lastly, inferring future changes in RI from the CM is feasible only for small return periods and at locations where mFOC is close to zero.

Repetitive passive movement (PM) affects corticospinal excitability; however, it is unknown whether a duty cycle which repeats movement and rest, or subjects’ conscious attention to movements, affects corticospinal excitability. We aimed to clarify the effect of the presence or absence of a duty cycle and subjects’ attention on corticospinal excitability. Three experiments were conducted. In Experiment 1, PM of the right index finger was performed for 10 min. Three conditions were used: (1) continuous PM (cPM) at a rate of 40°/s; (2) intermittent PM (iPM) with a duty cycle at 40°/s; and (3) iPM at 100°/s. In conditions 1 and 3, motor evoked potential (MEP) amplitude was significantly reduced. In Experiment 2, PM was performed for 30 min: condition 1 comprised cPM at a rate of 40°/s and Condition 2 comprised iPM at 40°/s. MEP amplitude significantly decreased in both conditions. In Experiment 3, PM was performed for 10 min: condition 1 comprised paying attention to the moving finger during iPM and Condition 2 was similar to Condition 1 but while counting images on a monitor without looking at the movement finger, and Condition 3 comprised counting images on a monitor without performing PM. MEP amplitude significantly increased only under Condition 1. Thus, afferent input from movements above a certain threshold may affect corticospinal excitability reduction. Furthermore, corticospinal excitability increases when paying attention to passive finger movement.

Depression is a common mental health problem with a higher prevalence in medical students than in the general population. This study aims to investigate the association between depressive symptoms, particularly those in each domain of the Center for Epidemiological Studies Depression (CES-D) Scale, and related factors. A cross-sectional study was conducted with a random sample of 1319 medical students at Haiphong University of Medicine and Pharmacy in 2016. The CES-D scale and a self-reported questionnaire were used to identify the prevalence of depressive symptoms and related risk factors. Univariate and multivariate logistic regression were performed to assess the risk factors associated with depressive symptoms and the score for each structure factor. Depressive symptoms were observed in 514 (39%) students, including more males than females (44.2% vs 36.9%, p = 0.015). Students whose mothers' highest education level was primary school had a higher prevalence of depressive symptoms than students whose mothers had higher education levels (p = 0.038). There was a significant relationship between depressive symptoms and stressful life events, especially a decline in personal health. A higher correlation was found between the somatic complaints and depressive affect domains. The impacts of risk factors differed for each domain of the depression scale. Only the factor of achieving excellence showed no statistically significant associations with depressive symptoms and the scores on the four domains considered in this study. The high prevalence of depressive symptoms among medical students with risk factors and the impact of these risk factors on each domain of depression scale need further clarification to alleviate depression in students during their medical training.

A method for producing ferulic acid by ultrasound-assisted, homogeneous, base-catalyzed hydrolysis of γ-oryzanol was developed. Experiments were conducted using various reaction temperatures and ratios of γ-oryzanol to base catalyst in both homogeneous and heterogeneous systems. The reaction performed without ultrasound under the homogeneous conditions of potassium hydroxide/γ-oryzanol ratio (wt/wt) 20 : 1 and 75°C gave a ferulic acid yield of 83.3% in 3 h. Acceleration of the homogeneous reaction using ultrasound irradiation at 20 (horn type) and 200 kHz (planar type) was explored by evaluating the kinetic parameters. At 30°C, the ratios of ultrasonic irradiation at low (20 kHz, 50 W) and high (200 kHz, 50 W) frequencies versus those of the heating method increased by 2.0- and 1.4-fold in comparison with those at 60°C, respectively. The contribution of ultrasonic irradiation (50 W) to the hydrolysis reaction decreased with increase of temperature. However, irradiation at 20 kHz and a power of 180 W gave a 94% ferulic acid yield at 60°C in 3 h. These results indicate that the use of low frequency (horn type and high-power irradiation) enabled yields higher than 90% to be obtained.

Combined heat and power production from biogas is now playing an important role in energy and resource utilization as well as pollution control in waste water treatment. This research used biogas from the Bali Sewage Treatment Plant in New Taipei City, Taiwan, as a major source of fuel for the electricity generation. A micro gas turbine electricity generator, Capstone CR-30, which possesses a maximum rated power load (PWL) of 30 kW, was equipped to convert biogas into electricity. The biogas is mainly composed of CH4 (56.1 ± 8.0 vol.%), CO2 (25.5 ± 9.8 vol.%), H2 (0.5 vol.%), and H2S (0.99 ± 0.07 ppmv). During the test operation period of the generator, it was found that the thermal efficiency increases from 19.8% to 23.4% kWhe/kWhth, while the electricity generation efficiency (ηEB) also rises from 0.93 to 1.09 kWhe/m3 biogas as the PWL increases from 10 kW to 30 kW. The results indicated that the generator has a better performance with higher PWL. At PWL = 30 kW, the average adjusted concentrations of CO and NOx (adjusted to 15 vol.% O2) emitted from the generator are 86 ppmv and 17 ppmv, respectively. Both are much lower than the emission standards of stationary sources in Taiwan of 2000 ppmv and 150 ppmv, respectively. Thus, PWL of 30 kW was selected in cooperation with biogas inflow = 0.412 m3/min and air/fuel ratio (i.e., air/biogas ratio) = 76.0 vol./vol. for the long-term regular operation. At the above setting conditions for long-term operation, the generator continuously consumed the biogas and provided stable electricity generation at a rate of 19.64 kWhe/h for a 2-year running period. Moreover, the greenhouse gas can be cut off with a rate of 10.78 kg CO2e/h when using biogas as fuel for electricity generation. Overall, this research proves that the application of a micro gas turbine electricity generator not only has promising performance for using biogas but also gives a significant reduction of greenhouse gas emission, which fits the concepts of the circular economy and environmental protection.

The treatment of nutrients and organic contaminants in wastewater using microalgae has drawn significant interest thanks to its advantages of environmental friendliness, low cost, CO2 emission reduction, and recycling of valuable biomass. Among other algae species, Chlorella sp. showed good vitality, simplicity in cultivation, and high nutrient accumulation in harsh conditions of wastewater. In this study, Chlorella vulgaris was inoculated in a membrane photobioreactor (MPBR) with piggery digestate to investigate the C. vulgaris growth rate and the removal efficiency of nutrients and chemical oxygen demand (COD). The results indicated that the cultivation of C. vulgaris in an MPBR system exhibited continuous and simultaneous removal of NH4+, PO43−, and COD from two-fold diluted piggery wastewater. Both the algae growth rate and nutrient removal depended on the liquid hydraulic retention time in the MPBR. The highest removal efficiency of NH4+ (74.55%), PO43− (70.20%), and COD (65.85%) was obtained in the longest HRT of 5 days with the highest microalgae biomass concentration of around 1.1 g/L. The algae washout phenomenon was negligible in the continuous cultivation in the MPBR system. Compared to the cultivation in batch mode, the MPBR could achieve a similar algae growth rate and treatment efficiency with a much shorter hydraulic retention time. [ABSTRACT FROM AUTHOR]

Future climate projections and their uncertainties affect many aspects of the world, so reliable assessments are essential for policymakers who need to prepare mitigation measures in the context of climate change. In this study, we examined the projected future climate and estimated uncertainty for South Korea using results from the global climate model (GCM), updated from the sixth phase of the coupled model intercomparison project (CMIP6); we then compared the differences in outcome between the fifth and sixth phases of the CMIP (CMIP5 and CMIP6). Future projections were estimated as the averaged climatological mean (denoted as C M ¯ ) for the four proposed hydrological indicators. Model uncertainty (UEMI) and stochastic uncertainty (USTO) were quantified as the range of ensembles of the climatological mean, while the emission uncertainty (UEMI) was estimated as the difference between the C M ¯ values of two emission scenarios. The following are the key findings of our study: (1) using an ensemble of multiple GCMs is recommended over using individual GCMs, and models in CMIP6 performed better for reproducing climate during the control period than models in the CMIP5; (2) the C M ¯ values in the CMIP6 increased for future periods, especially toward the end of this century, increasing mean temperature (meanTa) by approximately 5 °C, total precipitation (totPr), and daily maximum precipitation (maxDa) by about 20%, and these values were higher than those of the CMIP5; (3) the UGCM, USTO, and UEMI values increased for future periods in most of the indices; (4) the UGCM (for meanTa, totPr, and maxDa) and USTO (for totPr and maxDa) magnitudes in the CMIP6 were higher than those in the CMIP5, while the UEMI values between the two CMIPs were similar for all of the indices; (5) the UGCM was the major source of the largest uncertainty for meanTa, the USTO had a significant impact on future projections of totPr and maxDa, especially in the summer, and the UEMI became the dominant source of uncertainty for projecting the future meanTa, especially in the period farthest from the present. These results should provide useful information for studies that quantify future climate-induced hydrological impacts. [ABSTRACT FROM AUTHOR]

Ultrasound (US) is the primary imaging technique for the diagnosis of thyroid cancer. However, accurate identification of nodule malignancy is a challenging task that can elude less-experienced clinicians. Recently, many computer-aided diagnosis (CAD) systems have been proposed to assist this process. However, most of them do not provide the reasoning of their classification process, which may jeopardize their credibility in practical use. To overcome this, we propose a novel deep learning (DL) framework called multi-attribute attention network (MAA-Net) that is designed to mimic the clinical diagnosis process. The proposed model learns to predict nodular attributes and infer their malignancy based on these clinically-relevant features. A multi-attention scheme is adopted to generate customized attention to improve each task and malignancy diagnosis. Furthermore, MAA-Net utilizes nodule delineations as nodules spatial prior guidance for the training rather than cropping the nodules with additional models or human interventions to prevent losing the context information. Validation experiments were performed on a large and challenging dataset containing 4554 patients. Results show that the proposed method outperformed other state-of-the-art methods and provides interpretable predictions that may better suit clinical needs. [ABSTRACT FROM AUTHOR]

We investigated changes in some laboratory indices and the liver histology of chronic hepatitis patients who were exposed to dioxin. In 2014, we collected liver biopsy samples for histopathological examination from 33 chronic hepatitis patients living around the Da Nang Airbase, which is a dioxin-contaminated area due to the herbicide spraying in Vietnam. Dioxin exposure was measured by its levels in the blood. METAVIR classification was used to clarify the liver fibrosis stage. Laboratory tests included ten biochemical and six hematological indices that were measured in the blood. A regression linear model and binary logistic regression were used for data analysis. The observed alterations in the liver at the histological level mainly comprised hydropic degenerative hepatocytes, lymphocytes and polynuclear leukocytes surrounding the liver cells and granular and lipoic degeneration. In addition, increased TCDD levels were associated with increasing aminotransferase (AST), alanine aminotransferase, protein and total bilirubin levels and liver fibrosis stage. Similarly, increased TEQ-PCDD/Fs levels were associated with higher levels of AST and protein and liver fibrosis stage. In conclusion, dioxin exposure altered the liver histology and increased some biochemical marker indices and the liver fibrosis stage of chronic hepatitis patients living in dioxin-contaminated areas in Da Nang, Vietnam. [ABSTRACT FROM AUTHOR]

The effects of tuna viscera hydrolysate (TVH) on juvenile pompano Trachinotus blochii, growth performance, nutritional response, intestinal and liver health, and resistance to Streptococcus iniae were investigated in this study. Five isonitrogenous and isocaloric diets (protein 46.0%, lipid 10.0%) were formulated in which TVH was added to replace fishmeal protein at levels of 0 (control), 30, 60, 90, and 120 g kg-1, labelled as TVH0, TVH05, TVH10, TVH15, and TVH20, respectively. Triplicate groups of pompano were fed the respective diets for ten weeks. The results showed that fish fed diets containing TVH10 produced significantly higher final body weight and specific growth rate in comparison to the fishmeal control (P < 0.05). Dietary TVH did not produce any effect on feed utilisation, somatic indices, and proximate composition of juvenile pompano (P > 0.05). While most amino acids were unchanged by the dietary inclusion of TVH, phenylalanine and valine levels were significantly lower in the fish fed TVH20 diet compared to the control. Fish fed the TVH20 diet had significantly lowered total serum protein compared to the TVH10 treatment, whereas other biochemical parameters in the blood did not show any difference among treatments. The intestinal histology indicated a significant increase in goblet cell numbers in fish fed TVH10 diet. Fish fed diet supplemented with TVH showed the highest disease resistance against Streptococcus iniae after 14 days of challenge. Based on a quadratic regression between final body weight and dietary TVH levels, the optimum TVH was calculated to be 10% or 60.0 g kg-1 for maximum growth performance when fed to pompano. [ABSTRACT FROM AUTHOR]

A decrease in cortical excitability tends to be easily followed by an increase induced by external stimuli via a mechanism aimed at restoring it; this phenomenon is called "homeostatic plasticity." In recent years, although intervention methods aimed at promoting motor learning using this phenomenon have been studied, an optimal intervention method has not been established. In the present study, we examined whether subsequent motor learning can be promoted further by a repetitive passive movement, which reduces the excitability of the primary motor cortex (M1) before motor learning tasks. We also examined the relationship between motor learning and the brain-derived neurotrophic factor. Forty healthy subjects (Val/Val genotype, 17 subjects; Met carrier genotype, 23 subjects) participated. Subjects were divided into two groups of 20 individuals each. The first group was assigned to perform the motor learning task after an intervention consisting in the passive adduction–abduction movement of the right index finger at 5 Hz for 10 min (RPM condition), while the second group was assigned to perform the task without the passive movement (control condition). The motor learning task consisted in the visual tracking of the right index finger. The results showed that the corticospinal excitability was transiently reduced after the passive movement in the RPM condition, whereas it was increased to the level detected in the control condition after the motor learning task. Furthermore, the motor learning ability was decreased immediately after the passive movement; however, the motor performance finally improved to the level observed in the control condition. In individuals carrying the Val/Val genotype, higher motor learning was also found to be related to the more remarkable changes in corticospinal excitability caused by the RPM condition. This study revealed that the implementation of a passive movement before a motor learning tasks did not affect M1 excitatory changes and motor learning efficiency; in contrast, in subjects carrying the Val/Val polymorphism, the more significant excitatory changes in the M1 induced by the passive movement and motor learning task led to the improvement of motor learning efficiency. Our results also suggest that homeostatic plasticity occurring in the M1 is involved in this improvement. [ABSTRACT FROM AUTHOR]

Background: Use of tacrolimus (Tac) is pivotal to renal transplant (RT) immunosuppressive maintenance regiments. The most frequently used means of Tac monitoring is the measurement of the trough concentration (C0) in whole blood to maintain drug efficacy and minimize the consequences of overexposure. Most previous studies focused on therapeutic drug monitoring of Tac in renal transplant recipients and assessed the clinical response of patients. Our study aimed to describe a real Tacrolimus therapeutic drug monitoring transplantation and determine the clinical outcomes in Vietnamese adult renal transplant recipients. Methods: This retrospective study including 114 adult renal transplant patients (89 men and 25 women) with a mean age of 35.4 ± 8.98 years has been performed from August 2012 to March 2018 at Military Hospital 103 (Vietnam). Tac trough concentrations were adjusted according to the target range proposed by the European consensus conference on tacrolimus optimization. Samples for determination of tacrolimus blood levels were subdivided according to the post- transplantation period into three groups (0- 3 months (G1), 3-12 months (G2) and over 1 year (G3). Median Years of follow-up was 15.4 months [range 0.233 to 68.4 months]. Results: A total of 3037 blood samples for the determination of tacrolimus trough concentration were obtained. Median concentrations were 6.7 (4.5 - 10.2) ng/ml, 6.4 (5.1 - 8.3) and 5.6 (4.5 to 7.1) ng/ml for G1, G2, G3, respectively. After transplantation, three acute rejection (AR) events were documented (Cellular AR: 2, Humoral AR: 1). Cytomegalovirus, BK polyomavirus, Hepatitis B virus and Hepatitis C virus were detected in 7, 4, 7 and 3 renal post- transplant recipients, respectively. There were 5 patients with post-transplant diabetes (NODAT) and all of them had to convert to cyclosporine. 6 patients developed chronic kidney disease (CKD) after transplantation and 2 case with Tac-associated nephrotoxicity with proven biopsy. This observational study provided a real Tacrolimus therapeutic drug monitoring transplantation in Vietnamese renal transplant recipients. Main outcomes were acute rejection, post-transplant viral infections, neurotoxicity, NODAT, CKD, and Tac-associated nephrotoxicity. [ABSTRACT FROM AUTHOR]

Adaptive Neuro-Fuzzy Inference System (ANFIS) is a robust method in solving non-linear classification by employing a human-readable interpretation manner. This paper verified a hybrid model, named WANFIS, where Whale Optimization Algorithm (WOA) was used for feature selection and tuning parameters of the ANFIS for land-cover classification. Hanoi, the capital of Vietnam, was selected as a case study, because of its complex surface morphology. The model was trained and validated with different data sets, which were subsets of the segmented objects from SPOT 7 satellite data (1.5 m in panchromatic and 6 m multiple spectral bands). The image segmentation was carried out by using PCI Geomatics software (evaluation version), and output objects with associated spectral, shape, and metric information were selected as input data to train and validate the proposed model. For accuracy assessment, the performance of the model was compared to several benchmarked classifiers by using standard statistical indicators such as Receiver Operator Characteristics, Area under ROC, Root Mean Square Error, Absolute Mean Error, Kappa index, and Overall accuracy. The results showed that WANFIS outperformed the other in almost all training data sets for both operations. It could be concluded that the examination of the classification model in different training data sizes is significant, and the proper determination of predictor variables and training sizes would improve the quality of classification of remotely sensed data. [ABSTRACT FROM AUTHOR]

Repetitive passive movement (PM) affects corticospinal excitability; however, it is unknown whether a duty cycle which repeats movement and rest, or subjects' conscious attention to movements, affects corticospinal excitability. We aimed to clarify the effect of the presence or absence of a duty cycle and subjects' attention on corticospinal excitability. Three experiments were conducted. In Experiment 1, PM of the right index finger was performed for 10 min. Three conditions were used: (1) continuous PM (cPM) at a rate of 40°/s; (2) intermittent PM (iPM) with a duty cycle at 40°/s; and (3) iPM at 100°/s. In conditions 1 and 3, motor evoked potential (MEP) amplitude was significantly reduced. In Experiment 2, PM was performed for 30 min: condition 1 comprised cPM at a rate of 40°/s and Condition 2 comprised iPM at 40°/s. MEP amplitude significantly decreased in both conditions. In Experiment 3, PM was performed for 10 min: condition 1 comprised paying attention to the moving finger during iPM and Condition 2 was similar to Condition 1 but while counting images on a monitor without looking at the movement finger, and Condition 3 comprised counting images on a monitor without performing PM. MEP amplitude significantly increased only under Condition 1. Thus, afferent input from movements above a certain threshold may affect corticospinal excitability reduction. Furthermore, corticospinal excitability increases when paying attention to passive finger movement. [ABSTRACT FROM AUTHOR]

Depression is a common mental health problem with a higher prevalence in medical students than in the general population. This study aims to investigate the association between depressive symptoms, particularly those in each domain of the Center for Epidemiological Studies Depression (CES-D) Scale, and related factors. A cross-sectional study was conducted with a random sample of 1319 medical students at Haiphong University of Medicine and Pharmacy in 2016. The CES-D scale and a self-reported questionnaire were used to identify the prevalence of depressive symptoms and related risk factors. Univariate and multivariate logistic regression were performed to assess the risk factors associated with depressive symptoms and the score for each structure factor. Depressive symptoms were observed in 514 (39%) students, including more males than females (44.2% vs 36.9%, p = 0.015). Students whose mothers’ highest education level was primary school had a higher prevalence of depressive symptoms than students whose mothers had higher education levels (p = 0.038). There was a significant relationship between depressive symptoms and stressful life events, especially a decline in personal health. A higher correlation was found between the somatic complaints and depressive affect domains. The impacts of risk factors differed for each domain of the depression scale. Only the factor of achieving excellence showed no statistically significant associations with depressive symptoms and the scores on the four domains considered in this study. The high prevalence of depressive symptoms among medical students with risk factors and the impact of these risk factors on each domain of depression scale need further clarification to alleviate depression in students during their medical training. [ABSTRACT FROM AUTHOR]

This study investigated the torrefaction of de-oiled Jatropha seed residue after a two-stage sequential process consisting of mechanical screw pressing and solvent extraction using n-hexane (denoted as JMS). The optimal torrefaction temperature (Tr) and torrefaction time (tr) were determined in the ranges of 260–300 °C and 10–60 min, respectively, so to achieve a better heating value and satisfactory energy densification (ED) with acceptable mass loss. Thermogravimetric analysis was employed to elucidate the thermal decomposition behaviors of JMS. By comparison with the torrefaction of Jatropha seed residue after mechanical oil extraction by screw pressing only (namely, JMET), the results indicated that the ED of the torrefaction of JMS yielding the torrefied product JMST (two-stage product) was higher than that of the torrefaction of JME giving the torrefied product JMET (single-stage product). Further, it was found that JMET contained some tar, which was attributed to a thermal reaction in the residual oil in JME during torrefaction. The tar/oil content of JMET was about 1.0–1.8 wt.% in the determined optimal conditions. Thus, the enhanced recovery of the residual oil is advantageous not only because it allows obtaining more oil from Jatropha seed residue with a positive net energy gain but also because it prevents the formation of tar in torrefied biomass products. [ABSTRACT FROM AUTHOR]

Designing water infrastructure requires information about the magnitude and frequency of upcoming rainfall. A limited range of data offers just one of many realizations that occurred in the past or will occur in the future; thus, it cannot sufficiently explain climate internal variability (CIV). In this study, future relationships among rainfall intensity (RI), duration, and frequency (called the IDF curve) are established by addressing the CIV and tail characteristics with respect to frequency. Specifically, 100 ensembles of 30-year time series data were created to quantify that uncertainty. Then, the tail characteristics of future extreme rainfall events were investigated to determine whether they will remain similar to those in the present. From the RIs computed for control and future periods under two emission scenarios, following are the key results. Firstly, future RI will increase significantly for most locations, especially near the end of this century. Secondly, the spatial distributions and patterns indicate higher RI in coastal areas and lower RI for the central inland areas of South Korea, and those distributions are similar to those of the climatological mean (CM) and CIV. Thirdly, a straightforward way to reveal whether the tail characteristics of future extreme rainfall events are the same as those in the present is to inspect the slope value for the factor of change (FOC), m F O C . Fourthly, regionalizing with nearby values is very risky when investigating future changes in precipitation frequency estimates. Fifthly, the magnitude of uncertainty is large when the data length is short and gradually decreases as the data length increases for all return periods, but the uncertainty range becomes much greater as the return period becomes large. Lastly, inferring future changes in RI from the CM is feasible only for small return periods and at locations where m F O C   is close to zero. [ABSTRACT FROM AUTHOR]

The retrieval of chlorophyll-a (Chl-a) concentrations relies on empirical or analytical analyses, which generally experience difficulties from the diversity of inland waters in statistical analyses and the complexity of radiative transfer equations in analytical analyses, respectively. Previous studies proposed the utilization of artificial neural networks (ANNs) to alleviate these problems. However, ANNs do not consider the problem of insufficient in situ samples during model training, and they do not fully utilize the spatial and spectral information of remote sensing images in neural networks. In this study, a two-stage training is introduced to address the problem regarding sample insufficiency. The neural network is pretrained using the samples derived from an existing Chl-a concentration model in the first stage, and the pretrained model is refined with in situ samples in the second stage. A novel convolutional neural network for Chl-a concentration retrieval called WaterNet is proposed which utilizes both spectral and spatial information of remote sensing images. In addition, an end-to-end structure that integrates feature extraction, band expansion, and Chl-a estimation into the neural network leads to an efficient and effective Chl-a concentration retrieval. In experiments, Sentinel-3 images with the same acquisition days of in situ measurements over Laguna Lake in the Philippines were used to train and evaluate WaterNet. The quantitative analyses show that the two-stage training is more likely than the one-stage training to reach the global optimum in the optimization, and WaterNet with two-stage training outperforms, in terms of estimation accuracy, related ANN-based and band-combination-based Chl-a concentration models. [ABSTRACT FROM AUTHOR]

The effects of ultrasonic and ozonation pretreatments on organic solubilization, anaerobic biodegradability, and biogas production were elucidated in this study. Two pretreatment methods for batch anaerobic digestion for biogas recovery with the same material and experimental conditions were the focus for comparison. Anaerobic digestion experiments were conducted at ambient temperature with the solid retention time set to 25 days. The obtained results indicated that the soluble chemical oxygen demand increased from 0.344 without pretreatment to 1.023 and 1.228 g/L with ultrasound and ozone pretreatments, respectively, whereas the yields of biogas production in the 25 days increased by 32.3 and 52.9% via ultrasonic irradiation and ozonation relative to the control case, respectively. The biodegradability of the organic compounds of the samples for the cases of ultrasound, ozone pretreatments, and control achieved 55.9, 64.31, and 39.18%, respectively, in terms of chemical oxygen demand (COD) removal efficiencies. The physicochemical characteristics of sludge flocs were investigated via scanning with particle sizes, which were obviously affected by pretreatments of sonication and ozonation, resulting in finer particles than in the control case. [ABSTRACT FROM AUTHOR]

Combined heat and power production from biogas is now playing an important role in energy and resource utilization as well as pollution control in waste water treatment. This research used biogas from the Bali Sewage Treatment Plant in New Taipei City, Taiwan, as a major source of fuel for the electricity generation. A micro gas turbine electricity generator, Capstone CR-30, which possesses a maximum rated power load (PWL) of 30 kW, was equipped to convert biogas into electricity. The biogas is mainly composed of CH4 (56.1 ± 8.0 vol.%), CO2 (25.5 ± 9.8 vol.%), H2 (0.5 vol.%), and H2S (0.99 ± 0.07 ppmv). During the test operation period of the generator, it was found that the thermal efficiency increases from 19.8% to 23.4% kWhe/kWhth, while the electricity generation efficiency (ηEB) also rises from 0.93 to 1.09 kWhe/m3 biogas as the PWL increases from 10 kW to 30 kW. The results indicated that the generator has a better performance with higher PWL. At PWL = 30 kW, the average adjusted concentrations of CO and NOx (adjusted to 15 vol.% O2) emitted from the generator are 86 ppmv and 17 ppmv, respectively. Both are much lower than the emission standards of stationary sources in Taiwan of 2000 ppmv and 150 ppmv, respectively. Thus, PWL of 30 kW was selected in cooperation with biogas inflow = 0.412 m3/min and air/fuel ratio (i.e., air/biogas ratio) = 76.0 vol./vol. for the long-term regular operation. At the above setting conditions for long-term operation, the generator continuously consumed the biogas and provided stable electricity generation at a rate of 19.64 kWhe/h for a 2-year running period. Moreover, the greenhouse gas can be cut off with a rate of 10.78 kg CO2e/h when using biogas as fuel for electricity generation. Overall, this research proves that the application of a micro gas turbine electricity generator not only has promising performance for using biogas but also gives a significant reduction of greenhouse gas emission, which fits the concepts of the circular economy and environmental protection. [ABSTRACT FROM AUTHOR]

A new species of the genus Vietnamophryne is described from Vietnam on the basis of two specimens collected from Tuyen Quang Province, Northeastern Vietnam. The new species is morphologically most similar to Vietnamophryne occidentalis from Thailand, however, it differs from the latter by having large black blotches in the lower jaw region, and a yellow-orange chest and belly. The genetic distance between the new species and other Vietnamophryne taxa is > 2.13% (16S mtDNA gene fragment). Vietnamophryne aurantifusca sp. nov. can be distinguished from all other species of Vietnamophryne by a combination of the following morphological characteristics: Size medium (SVL 17.618.2 mm in males); head wider than long; tympanum medium; finger I longer than half of finger II; dorsal skin relatively smooth with some round nodules, concentrated in the middle of the back, arranged along the length of the back, with a prominent ridge along the spine; Dorsum orangish-brown entirely and paler on margin of back with a small brownish ridge along the spine; sides brownish with creamy patches and orange spots; ventral surface orange, with grey marbling, most intense on the throat, ventral side of arms and thighs, and ventral surfaces of limbs dark grey with some orange spots.

We describe a new species of Dendrelaphis from the coastal area in southern Vietnam based on morphological data and nucleotide sequences from one partial mitochondrial gene (Cytb). Dendrelaphis binhi sp. nov. is diagnosed by the following morphological characters: body scale rows 13 at neck and midbody, 9-11 before vent; vertebral scale row feebly enlarged; ventrals 154-158 in males and 161-170 in females; subcaudals 95-106 in males and 95-102 in females; one supralabial touching the eye; 18 or 19 maxillary teeth; hemipenis spinose, reaching 10th or 11th SC, with a slender papilla; cloacal plate divided; dorsum dark brown; and a white stripe along the lower flank. The new species differs from its congeners by an uncorrected p-distance in Cytb sequences of at least 8.1%.

We describe a new species of kukri snake from Da Lat City and its vicinity in Lam Dong Province, southern Vietnam on the basis of morphological characters of four specimens, including two males and two females. Oligodon tuani sp. nov. differs from other congeners by a combination of the following characters: large size in adults (TL ≤ 888 mm); 19 dorsal scale rows at midbody; ventrals 173-179 in males and 187-193 in females; subcaudals 58 or 59 in males and 44 or 45 in females; presubocular present; 8 supralabials, fourth and fifth entering orbit; cloacal plate undivided; 10 maxillary teeth, posterior three enlarged; vertebral stripe present; temporal streak present but faint and interrupted; long and deeply forked hemipenes, extending to 25th subcaudal, without spines and papillae; and 13-15+3-4 dorsal blotches.

Introduction: It is widely known that motor learning changes the excitability of the primary motor cortex. More recently, it has been shown that the primary somatosensory cortex (S1) also plays an important role in motor learning, but the details have not been fully examined. Therefore, we investigated how motor skill training affects somatosensory evoked potential (SEP) in 30 neurologically healthy subjects., Methods: SEP N20/P25&#95;component and N20/P25 SEP paired-pulse depression (SEP-PPD) were assessed before and immediately after complex or simple visuomotor tasks., Results: Motor learning was induced more efficiently by the complex visuomotor task than by the simple visuomotor task. Both the N20/P25 SEP amplitude and N20/P25 SEP-PPD increased significantly immediately after the complex visuomotor task, but not after the simple visuomotor task. Furthermore, the altered N20/P25 SEP amplitude was associated with an increase in motor learning efficiency., Conclusion: These results suggest that motor learning modulated primary somatosensory cortex excitability., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2022 Pham, Saito, Miyaguchi, Watanabe, Ikarashi, Nagasaka, Yokota, Kojima, Inukai, Otsuru and Onishi.)

We describe a new species of the genus Subdoluseps Freitas, Datta-Roy, Karanth, Grismer Siler from a coastal area in southern Vietnam. Subdoluseps vietnamensis sp. nov. is characterized by the following morphological characters: medium size in adults (snout-vent length up to 48.7 mm); tail length/snout-vent length ratio 1.04; toes not reaching finger when limbs adpressed; 27-30 midbody scale rows, smooth; 55-57 paravertebral scales; 55-62 ventral scale rows; 64-74 subcaudal scales; frontoparietal scale single; four supraoculars; prefrontals not in contact with one another; two loreal scales; seven supralabials; ear-opening with two lobules on the anterior border; smooth lamellae beneath finger III 9 or 10 and toe IV 12-15; six enlarged precloacal scales; and four distinct black stripes on dorsum. The new species differs genetically from its closest congeners, S. bowringii (Günther) and S. frontoparietale (Taylor), by uncorrected p-distances of 10.0% and 9.5%, respectively in ND1 sequences, and clusters into the same matriline with these two congeners on the phylogenetic trees.