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Your search keyword '"Mahler, Donald A."' showing total 384 results
Start Over Author "Mahler, Donald A." Publication Type Academic Journals
384 results on '"Mahler, Donald A."'

1. Guidance on Mitigating the Risk of Transmitting Respiratory Infections During Nebulization by the COPD Foundation Nebulizer Consortium

Author

Biney, Isaac N., Ari, Arzu, Barjaktarevic, Igor Z., Carlin, Brian, Christiani, David C., Cochran, Lauren, Drummond, M. Bradley, Johnson, Karmon, Kealing, Dan, Kuehl, Philip J., Li, Jie, Mahler, Donald A., Martinez, Sergio, Ohar, Jill, Radonovich, Lewis J., Sood, Akshay, Suggett, Jason, Tal-Singer, Ruth, Tashkin, Donald, Yates, Julie, Cambridge, Lisa, Dailey, Patricia A., Mannino, David M., and Dhand, Rajiv

Published
2024
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10. Personalizing Selection of Inhaled Delivery Systems in Chronic Obstructive Pulmonary Disease.

Author

Mahler, Donald A. and Halpin, David M. G.

Subjects
CHRONIC obstructive pulmonary disease, PATIENT compliance, MEDICAL personnel
Abstract

It can be challenging for healthcare professionals (HCPs) to prescribe inhaled therapy for patients with chronic obstructive pulmonary disease (COPD) because of the multiple individual and combinations of inhaled medications available in numerous delivery systems. Guidance on the selection of an inhaled delivery system has received limited attention compared with the emphasis on prescribing the class of the inhaled molecule(s). Although numerous recommendations and algorithms have been proposed to guide the selection of an inhaled delivery system for patients with COPD, no specific approach has been endorsed in COPD guidelines/strategies or by professional organizations. To provide recommendations for an inhaler selection strategy at initial and follow-up appointments, we examined the impact of patient errors using handheld inhalers on clinical outcomes and performed a focused narrative review to consider patient factors (continuity of the inhaled delivery system, cognitive function, manual function/dexterity, and peak inspiratory flow) when selecting an inhaled delivery system. On the basis of these findings, five questions are proposed for HCPs to consider in the initial selection of an inhaler delivery system and three questions to consider at follow-up. We propose that HCPs consider the inhaled medication delivery system as a unit and to match appropriate medication(s) with the unique features of the delivery system to individual patient factors. Assessment of inhaler technique and adherence together with patient outcomes/satisfaction at each visit is essential to determine whether the inhaled medication delivery system is providing benefits. Continued and repeated education on device features and correct technique is warranted to optimize efficacy. [ABSTRACT FROM AUTHOR]

Published
2023
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16. American College of Chest Physicians Consensus Statement on the Management of Dyspnea in Patients With Advanced Lung or Heart Disease

Author

Mahler, Donald A., Selecky, Paul A., Harrod, Christopher G., Benditt, Joshua O., Carrieri-Kohlman, Virginia, Curtis, J. Randall, Manning, Harold L., Mularski, Richard A., Varkey, Basil, Campbell, Margaret, Carter, Edward R., Chiong, Jun Ratunil, Ely, E. Wesley, Hansen-Flaschen, John, O'Donnell, Denis E., and Waller, Alexander

Published
2010
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21. An Official American Thoracic Society/European Respiratory Society Statement: Research Questions in Chronic Obstructive Pulmonary Disease

Author

Celli, Bartolome R., Decramer, Marc, Wedzicha, Jadwiga A., Wilson, Kevin C., Agustí, Alvar, Criner, Gerard J., MacNee, William, Make, Barry J., Rennard, Stephen I., Stockley, Robert A., Vogelmeier, Claus, Anzueto, Antonio, Au, David H., Barnes, Peter J., Burgel, Pierre-Regis, Calverley, Peter M., Casanova, Ciro, Clini, Enrico M., Cooper, Christopher B., Coxson, Harvey O., Dusser, Daniel J., Fabbri, Leonardo M., Fahy, Bonnie, Ferguson, Gary T., Fisher, Andrew, Fletcher, Monica J., Hayot, Maurice, Hurst, John R., Jones, Paul W., Mahler, Donald A., Maltais, François, Mannino, David M., Martinez, Fernando J., Miravitlles, Marc, Meek, Paula M., Papi, Alberto, Rabe, Klaus F., Roche, Nicolas, Sciurba, Frank C., Sethi, Sanjay, Siafakas, Nikos, Sin, Don D., Soriano, Joan B., Stoller, James K., Tashkin, Donald P., Troosters, Thierry, Verleden, Geert M., Verschakelen, Johny, Vestbo, Jorgen, Walsh, John W., Washko, George R., Wise, Robert A., Wouters, Emiel F. M., and ZuWallack, Richard L.

Published
2015
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30. A Systematic Review of Published Algorithms for Selecting an Inhaled Delivery System in Chronic Obstructive Pulmonary Disease.

Author

Halpin, David M. G. and Mahler, Donald A.

Subjects
SYSTEMATIC reviews, BRONCHODILATOR agents, NEBULIZERS & vaporizers, OBSTRUCTIVE lung diseases, ALGORITHMS
Abstract

Rationale: Medication for treatment of chronic obstructive pulmonary disease (COPD) is available in many different delivery systems; however, national and international guidelines do not provide recommendations on how to select the optimal system for an individual patient. Objectives: To perform a systematic review of published algorithms for inhaler selection in outpatients with COPD. Methods: PubMed, EMBASE, PsycINFO, Cochrane, and Google Scholar were searched for articles on inhaler selection published between January 1, 1990, and March 10, 2021. The results were reviewed for articles containing an algorithm for inhaler selection. The quality of publications containing an algorithm was assessed using the Joanna Briggs Institute's System for the Unified Management, Assessment and Review of Information text and opinion critical appraisal checklist. Individual steps recommended in the algorithms and the order in which they were considered were extracted independently by the two authors using the Joanna Briggs Institute's text and opinion data extraction tool. Textual syntheses and a table of factors included were used to appraise and compare algorithms. Results: The search identified 1,016 publications. After removing duplicate studies (n = 409), 607 abstracts were examined. Nine different algorithms or hierarchical recommendations for device selection were identified. All nine publications were considered of good quality. Most algorithms contain only a few decision steps. There were significant differences between the algorithms. None of the algorithms have been validated. Three domains for factors included in the algorithms were identified: patient factors, device attributes, and healthcare professional (HCP) factors. Patient factors were considered most frequently (19 times) compared with device attributes (10 times) and HCP factors (7 times). Five specific attributes/factors with at least three rankings in different algorithms were identified as key factors for device selection: ability to perform the required inspiratory maneuver and handle device correctly, sufficient inspiratory flow for dry powder inhalers, availability of molecule(s) in the device, and continuity of device. Conclusions: Although the algorithms generally provide step-by-step approaches based on a literature review and/or the experiences of the different authors, none were developed using item generation/reduction methodology or included input from patients with COPD. However, the review identified key factors that should be considered by HCPs when selecting therapy. Registration: PROSPERO (CRD42021244475). [ABSTRACT FROM AUTHOR]

Published
2022
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45. The Safety and Efficacy of Infliximab in Moderate to Severe Chronic Obstructive Pulmonary Disease

Author

Rennard, Stephen I., Fogarty, Charles, Kelsen, Steven, Long, William, Ramsdell, Joe, Allison, James, Mahler, Donald, Saadeh, Constantine, Siler, Thomas, Snell, Phillip, Korenblat, Phillip, Smith, William, Kaye, Mitchell, Mandel, Michael, Andrews, Charles, Prabhu, Rachakonda, Donohue, James F., Watt, Rosemary, Lo, Kim Hung, Schlenker-Herceg, Rozsa, Barnathan, Elliot S., and Murray, John

Published
2007
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