Search

Your search keyword '"Lombardi Davide"' showing total 351 results
Start Over Author "Lombardi Davide" Publication Type Academic Journals
351 results on '"Lombardi Davide"'

2. Novel cellular systems unveil mucosal melanoma initiating cells and a role for PI3K/Akt/mTOR pathway in mucosal melanoma fitness

Author

Monti, Matilde, Benerini Gatta, Luisa, Bugatti, Mattia, Pezzali, Irene, Picinoli, Sara, Manfredi, Marcello, Lavazza, Antonio, Vanella, Virginia Vita, De Giorgis, Veronica, Zanatta, Lucia, Missale, Francesco, Lonardi, Silvia, Zanetti, Benedetta, Bozzoni, Giovanni, Cadei, Moris, Abate, Andrea, Vergani, Barbara, Balzarini, Piera, Battocchio, Simonetta, Facco, Carla, Turri-Zanoni, Mario, Castelnuovo, Paolo, Nicolai, Piero, Fonsatti, Ester, Leone, Biagio Eugenio, Marengo, Emilio, Sigala, Sandra, Ronca, Roberto, Perego, Michela, Lombardi, Davide, and Vermi, William

Published
2024
Full Text
View/download PDF

3. Oncoplastic and reconstructive surgery in SENONETWORK Italian breast centers: lights and shadows

Author

Abbonante, Francesco, Lamanna, Ginevra, Lombardi, Augusto, Vischi, Silvio, Orzalesi, Lorenzo, Angiolucci, Giovanni, Bozzo, Samantha, Pizzorno, Laura, Ballardini, Bettina, Barbero, Maggiorino, Barellini, Leonardo, Battaglia, Claudio, Reggiani, Luisa, Santi, Caterina, Biglio, Nicoletta, Bortul, Marina, Burelli, Paolo, Busani, Massimo, Cabula, Roberta, Cagossi, Katia, Fontanarosa, Vito Maria, Catalano, Francesca, Cedolini, Carla, Ciuffreda, Luigi, Corsi, Fabio, Custodero, Olindo, Mori, Stefano, De Vita, Roy, Defilippi, Loredana, Marcuzzi, Samantha, Drago, Stefano, Battista, Giovanni, Burgoa, Loredana, Cristofolini, Paolo, Romanucci, Giovanna, Loreti, Andrea, Prosperi, Valerio, Carcoforo, Paolo, Franzini, Patrizia Fulvia, Frittelli, Patrizia, Perniciaro, Giuseppe, Generali, Daniele, Giordano, Monica, Riccardo, Giovanazzi, Grossi, Simona, Huscher, Alessandra, La Torre, Giuseppe, Lolli, Gianfranco, Magni, Carla, Mancini, Stefano, Galli, Lorenzo, Di Leone, Alba, Massarut, Samuele, Massocco, Alberto, Cramarossa, Monica, Meneghini, Graziano, Fabiocchi, Luca, Miglietta, Anna Maria, Millo, Francesco, Ciabattoni, Antonella, Pellini, Francesca, Moschetta, Marco, Musolino, Antonino, Palli, Dante, Pagura, Giulia, Pieraccini, Mariagrazia, Marenco, Davide, Polato, Romano, Renne, Maria, Ressa, Cosmo Maurizio, Ricci, Fabio, Ridolfo, Raffaella, Rovera, Francesca Angela, Barberini, Francesco, Vinciguerra, Marina, Furci, Marco, Sciamannini, Maria, Gianquinto, Daniela, Petrucci, Silvia, Della Valle, Angelica, Stancampiano, Pietra, Lippi, Andrea, Tazzioli, Giovanni, Lombardi, Davide, Trunfio, Martino, Valieri, Luca, Vecchio, Carlo, Veronesi, Paolo, Grilz, Gretha, Ghilli, Matteo, Lisa, Andrea Vittorio Emanuele, Salgarello, Marzia, Papa, Giovanni, Rietjens, Mario, Folli, Secondo, Curcio, Annalisa, Ferrari, Guglielmo, Caruso, Francesco, Altomare, Vittorio, Friedman, Daniele, De Santis, Maria Carmen, De Rose, Fiorenza, Meduri, Bruno, De Felice, Francesca, Marino, Lorenza, Cucciarelli, Francesca, Montemezzi, Stefania, Panizza, Pietro, Belli, Paolo, Caumo, Francesca, Vinci, Valeriano, De Santis, Giorgio, Klinger, Marco, and Roncella, Manuela

Published
2024
Full Text
View/download PDF

5. Late tamoxifen in patients previously operated for breast cancer without postoperative tamoxifen: 5-year results of a single institution randomised study

Author

Bidoli Ettore, Scalone Simona, Crivellari Diana, Magri Maria D, Miolo GianMaria, Veronesi Andrea, and Lombardi Davide

Subjects
Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Abstract Background A population of breast cancer patients exists who, for various reasons, never received adjuvant post-operative tamoxifen (TAM). This study was aimed to evaluate the role of late TAM in these patients. Methods From 1997 to 2003, patients aged 35 to 75 years, operated more than 2 years previously for monolateral breast cancer without adjuvant TAM, with no signs of metastases and no contraindication to TAM were randomized to TAM 20 mg/day orally for 2 years or follow-up alone. Events were categorized as locoregional relapse, distant metastases, metachronous breast cancer, tumours other than breast cancer and death from any causes, whichever occurred first. The sample size (197 patients per arm, plus 10% allowance) was based on the assumption of a 30% decrease in the number of events occurring at a rate of 5% annually in the 10 years following randomization. Four hundred and thirty-three patients were randomized in the study (TAM 217, follow-up 216). Patients characteristics (TAM/follow-up) included: median age 55/55 years, median time from surgery 25/25 months (range, 25-288/25-294), in situ carcinoma 18/24, oestrogen receptor (ER) positive in 75/68, negative in 70/57, unknown in 72/91 patients. Previous adjuvant treatment included chemotherapy in 131/120 and an LHRH analogue in 11/13 patients. Results Thirty-six patients prematurely discontinued TAM after a median of 1 month, mostly because of subjective intolerance. Eighty-three events (TAM 39, follow-up 44) occurred: locoregional relapse in 10/8, distant metastases in 14/16, metachronous breast cancer in 4/10, other tumours in 11/10 patients. Less ER-positive secondary breast cancers occurred in the TAM treated patients than in follow-up patients (1 vs 10, p = 0.005). Event-free survival was similar in both groups of patients. Conclusions This 5-year analysis revealed significantly less metachronous ER-positive breast cancers in the TAM treated patients. No other statistically significant differences have emerged thus far.

Published
2010
Full Text
View/download PDF

6. Selecting for BRCA1 testing using a combination of homogeneous selection criteria and immunohistochemical characteristics of breast cancers

Author

Scalone Simona, Perin Tiziana, Lombardi Davide, Dolcetti Riccardo, Puppa Lara, De Giacomi Clelia, Canzonieri Vincenzo, Miolo GianMaria, Veronesi Andrea, and Viel Alessandra

Subjects
Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Abstract Background BRCA1 gene-related tumours are more frequently estrogen receptor (ER) and progesterone receptor (PR) negative with a lower prevalence of human epidermal growth factor receptor 2 (HER2) overexpression or amplification. We evaluated the effectiveness of a combination of homogeneously selected criteria and immunohistochemical (IHC) characteristics of Familial Breast Cancers (FBCs) in detecting BRCA1 mutation carriers. Methods Primary breast tumours from 93 FBC patients defined by specific eligibility criteria, based on personal and familial tumour history, were evaluated by Allred's method. The BRCA1 molecular analysis, including Multiplex Ligation-dependent Probe Amplification (MLPA), was considered as the gold standard assay. Results A total of 10 BRCA1 pathogenetic mutations was found. With the exclusion of the tumours characterized by double positive receptorial status and/or strong HER2 positivity (3+), we identified 22 patients, 10 of whom resulted as BRCA1 mutation carriers. The sensitivity, specificity, positive and negative predictive values were 100%, 83.3%, 45.4% and 100% respectively. Conclusion Our findings suggest that the IHC analysis by Allred's method improves our ability to select patients for BRCA1 testing.

Published
2009
Full Text
View/download PDF

8. Familial breast cancer: characteristics and outcome of BRCA 1–2 positive and negative cases

Author

Viel Alessandra, Dolcetti Riccardo, Scuderi Cristina, Zanetti Martina, Lombardi Davide, Magri Maria D, Giacomi Clelia de, Veronesi Andrea, Crivellari Diana, Bidoli Ettore, and Boiocchi Mauro

Subjects
Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Abstract Background The clinical and pathological characteristics and the clinical course of patients with breast cancer and BRCA 1–2 mutation are poorly known. Methods From 1997, patients with breast cancer and a family history of breast or ovarian cancer were offered BRCA testing. The clinical and pathological features of patients with known BRCA status were retrospectively assessed and comparisons were made between cancers arising in BRCA positive and BRCA wild type (WT) patients respectively. Type of treatment, pattern of relapse, event (local relapse, contralateral breast cancer, metastases) free and overall survival were also compared in the two groups. Out of the 210 patients tested, 125 had been treated and followed-up at our Institution and were evaluated in this study. Results BRCA positive patients tended to be more often premenopausal (79% vs 65%) and to have positive lymphnodes (63% vs 49%), poorly differentiated tumours (76% vs 40% – p = 0.002 at univariate analysis, not significant at multivariate analysis) and negative estrogen receptors (43% vs 29%). Treatment was not different in the two groups. In the 86 BRCA-WT patients, the first event was a local relapse in 3 (3%), metachronous contralateral breast cancer in 7 (8%) and distant metastases in 16 (19%). In the 39 BRCA positive patients, the corresponding figures were 3 (8%), 8 (21%) and 3 (8%). There was no difference in event free survival, with a median of 180 months in both groups of patients. At 20 years, projected survival was 85% for BRCA positive patients and 55% for BRCA-WT, but this difference was not statistically significant. Conclusion Although BRCA positive patients have more frequently negative prognostic factors, their prognosis appears to be equal to or better than in patients with BRCA-WT.

Published
2005
Full Text
View/download PDF

9. Effects of hospital facilities on patient outcomes after cancer surgery: an international, prospective, observational study

Author

Knight, Stephen R, Shaw, Catherine A, Pius, Riinu, Drake, Thomas M, Norman, Lisa, Ademuyiwa, Adesoji O, Adisa, Adewale O, Aguilera, Maria Lorena, Al-Saqqa, Sara W, Al-Slaibi, Ibrahim, Bhangu, Aneel, Biccard, Bruce M, Brocklehurst, Peter, Costas-Chavarri, Ainhoa, Chu, Kathryn, Dare, Anna, Elhadi, Muhammed, Fairfield, Cameron J, Fitzgerald, J Edward, Ghosh, Dhruv, Glasbey, James, van Berge Henegouwen, Mark I., Ingabire, J.C. Allen, Kingham, T Peter, Lapitan, Marie Carmela, Lawani, Ismaïl, Lieske, Bettina, Lilford, Richard, Martin, Janet, McLean, Kenneth A, Moore, Rachel, Morton, Dion, Nepogodiev, Dmitri, Ntirenganya, Faustin, Pata, Francesco, Pinkney, Thomas, Qureshi, Ahmad Uzair, Ramos-De la Medina, Antonio, Riad, Aya, Salem, Hosni Khairy, Simões, Joana, Spence, Richard, Smart, Neil, Tabiri, Stephen, Thomas, Hannah, Weiser, Thomas G, West, Malcolm, Whitaker, John, Harrison, Ewen M, Gjata, Arben, Modolo, Maria Marta, King, Sebastian, Chan, Erick, Nahar, Sayeda Nazmun, Waterman, Ade, Vervoort, Dominique, Bedada, Alemayehu Ginbo, De Azevedo, Bernardo, Figueiredo, Ana Gabriela, Sokolov, Manol, Barendegere, Venerand, Ekwen, Gerald, Agarwal, Arnav, Liu, Qinyang, Camilo Correa, Juan, Malemo, Kalisya Luc, Bake, Jacques, Mihanovic, Jakov, Kunčarová, Kamila, Orhalmi, Julius, Salem, Hosni, Teras, Jyri, Kechagias, Aristotelis, Arnaud, Alexis P, Lindert, Judith, Kalles, Vasileios, Aguilera-Arevalo, Maria-Lorena, Recinos, Gustavo, Baranyai, Zsolt, Kumar, Basant, Neelamraju Lakshmi, Harish, Zachariah, Sanoop Koshy, Alexander, Philip, Kumar Venkatappa, Sunil, Pramesh, C, Amandito, Radhian, Fleming, Christina, Ansaloni, Luca, Pellino, Gianluca, Altibi, Ahmed M., Nour, Ibrahim, Hamdun, Intisar, Ghellai, Ali M., Venskutonis, Donatas, Poskus, Tomas, Zilinskas, Justas, Malemia, Precious, Tew, Yong Yong, Borg, Elaine, Ellul, Sarah, Wafqui, fatima Zahraa, Borowski, David W, van Dalen, Anne Sophie, Wells, Cameron, Adamou, Harissou, Ademuyiwa, Adesoji, Adisa, Adewale, Søreide, Kjetil, Al Saqqa, Sara, Alser, Osaid, Tahboub, Haya, Segovia Lohse, Helmut Alfredo, Shu Yip, Sebastian, Major, Piotr, Sampaio Soares, António, Bratu, Matei Razvan, Litvin, Andrey, Vardanyan, Armen, Allen Ingabire, JC, Gudal, Ahmad, Albati, Naif, Juloski, Jovan, Rems, Miran, Rayne, Sarah, Van Straten, Stephanie, Moodley, Yoshan, Ortega Vázquez, Irene, Ruiz-Tovar, Jaime, Senanayake, Kithsiri Janakantha, Thalgaspitiya, Sujeewa Priyantha Bandara, Omer, Omer Abdelbagi, Homeida, Anmar, Cengiz, Yucel, Clerc, Daniel, Alshaar, Muhammad, Bouaziz, Hanen, Altinel, Yuksel, Doe, Matthew, Freigofer, Maryna, Teasdale, Ella, Kabariti, Rakan, Clements, Joshua Michael, Knight, Stephen Richard, Ashfaq, Ahsan, Azodo, Ijeoma, Wagner, Gabriela, Trostchansky, Ivan, Maimbo, Mayaba, Linyama, David, Nina, Helidon, Zeko, Amanda, Fermani, Claudio Gabriel, Villalobos, Santiago, Carballo, Federico, Farina, Pablo, Guckenheimer, Sebastian, Dickfos, Marilla, Ajmera, Ankit, Chong, Chester, Gourlay, Ralph, Hussaini, Sikandar, Lee, Yi Jia, Majid, Adeeb, Martin, Peter, Miles, Rebecca, Morris, Owen James, Phua, Jamie, Ridley, William, Saluja, Tarunpreet, Tan, Ryan Renxin, Teh, Jen, Wells, Anna, Arora, Bharti, Dollie, Qaasim, Ho, Debbie, Ma, Yanru, Perera, Omattage Mahasha, Truong, Anthony, Dawson, Amanda Caroline, Lim, Bryan, Pahalawatta, Upuli, Phan, Jacqueline, Woon-Shoo-Tong, Xiao-Ming Sarah, Yeoh, Andrea, Charman, Lillian, Drane, Andrew, Laura, Sharon, Lo, Charmaine Chu Wen, Mozes, Amy, Poon, Rita, Tan, Hao Han, Wall, Ellen, Chopra, Prakshi, De Giovanni, Jasmine, Dhital, Bal, Draganic, Brian, Duller, Alexander, Gani, Jonathan, Goh, Yao Kuan, Jeong, Jun Young, McManus, Brendan, Nagappan, Prakash, Pockney, Peter, Rugendyke, Anya, Sarrami, Mahsa, Smith, Stephen, Wills, Vanessa, Wong, Hsu Ven, Ye, Geoffrey, Zhang, Geoffrey, Brooker, Ethan, Feng, Daniel, Lau, Bonnie, Ngai, Carlin, Birks, Sarah, Gyorki, David, Otero de Pablos, Jaime, Abbosh, Ali, Gillespie, Chris, Mahmoud, Ahmed, Kwan, Bianca, Lawson, Joshua, Warwick, Andrea, Bingham, Janne, Cockbain, Andrew J, Dudi-Venkata, Nagendra Naidu, Ellaby-Hall, Jordan, Finlay, Ben, Humphries, Emily, Pisaniello, Jade, Pisaniello, Monique, Salih, Salma, Sammour, Tarik, Abd Wahab, Haidar Hadri, De Silva, April, Hayward, Nicola, Iyer, Kartik, Maddern, Guy, Prevost, Gian Andrea, Annapureddy, Naga, Settipalli, Krishna Pranathi, Yeo, Jeremy, Hempenstall, Lucy, Pham, Lily, Purcell, Shaun, Talavera, Cherry, Vaska, Ashish I, Chaggar, Gurpreet, Chrapko, Phillip, Cocco, Annelise, Coulter-Nile, Sarah Michelle Crystal Jade, Ctercteko, Grahame, French, James, Gong, Houchen, Gosselink, Martijn, Jegathees, Thuvarahan, Jin, Ivan, Kalachov, Michelle, Kiefhaber, Kathryn, Lee, Katherine, Luong, Jason, Phan, Steven, Pleass, Henry, Veale, Kelly, Zeng, Zhi, Au, Angela, DeBiasio, Ashe, Deng, Idy, Myooran, Jananee, Nair, Amrita, Stewart, Peter, Stift, Anton, Unger, Lukas Walter, Wimmer, Kerstin, Ahmed, Nabila, Hasan, Syed, Rahman, Saber, O'Shea, Margaret, Padmore, Greg, Peters, Adrian, Perduca, Pietro, Pulcina, Guenda, Tinton, Nicolas, Buxant, Frederic, Dabin, Elsa, Garofalo, Giulia, Dossou, Francis, Gnangnon, Freddy Houehanou Rodrigue, Imorou Souaibou, Yacoubou, Motlaleselelo, Pako, Tlhomelang, Omphile, Lima Buarque, Igor, Mendonça Ataíde Gomes, Gustavo, Vieira Barros, Aldo, Batashki, Ilia, Damianov, Nikolai, Stoyanov, Vladislav, Dardanov, Dragomir, Maslyankov, Svilen, Petkov, Plamen, Todorov, George, Zhivkov, Evgeni, Akisheva, Aygulya, Castilla Moreno, Miguel Angel, Genov, Geno, Ilieva, Ivelina, Ivanov, Tsvetomir, Karamanliev, Martin, Khan, Azhar, Mitkov, Emil, Yotsov, Tsanko, Atanasov, Boyko, Belev, Nikolay, Slavchev, Mihail, Nsengiyumva, Carlos, Jones, Elgan, Stock, Simon, Kyota, Steve, Brown, James, Mabanza K., Tresor, Nigo Samuel, Lemery, Otuneme, Chidi, Prosper, Ngwang, Umenze, Franklin, Boutros, Marylise, Caminsky, Natasha, Dumitra, Sinziana, Garfinkle, Richard, Morency, Dominique, Salama, Ebram, Banks, Alexander, Ferri, Lorenzo, He, Haitian, Katz, Amit, Liberman, Alexander Sender, Meterissian, Sarkis, Pang, Allison, Parvez, Elena, Hameed, Usmaan, Osman, Fahima, Sequeira, Sangita, Coburn, Natalie, Jaffer, Alisha, Karanicolas, Paul, Mosseler, Matthew, Musselman, Reilly, Liu, Xinyuan, Yip, Ching Wan, Garces-Otero, Juan Sebastian, Guzman, Carolina, Sierra, Sebastian, Uribe Valencia, Andres, Cabrera Rivera, Paulo Andrés, Camelo, Saul, Gonzalez, Andrea, González-Orozco, Alejandro, Mosquera Paz, Manuel Santiago, Perez Rivera, Carlos J, Gonzalez, Felipe, Isaza-Restrepo, Andres, Nino- Torres, Laura, Arias Madrid, Natalia, Mendoza Arango, Maria Clara, Tsandiraki, Justin, Jemendžić, Damir, Kocman, Branislav, Šuman, Oliver, Canic, Renata, Jurišić, Darko, Karakas, Ivana, Krizanovic Rupcic, Ana, Pitlovic, Vlatka, Samardžić, Josip, Kopljar, Mario, Bacic, Ivan, Domini, Edgar, Karlo, Robert, Miljanić, Danijela, Simic, Andrea, Ahmed, Mariam, Al Nassrallah, Majdi, Altaf, Rabiya, Amjad, Talal, Eltoum, Ruba, Haidar, Heba, Hassan, Alhassan, Khalil, Omar, Qasem, Marwan, Ramesh, Rommel, Sajith, Gautham, Wisal, Maham, Žatecký, Jan, Bujda, Michele, Jirankova, Katerina, Paclik, Ales, Abdallah, Aya, Abdulgawad Almogy, Mariam, Ayman El-sawy, Esraa, ElFayoumy, Ahmed Moustafa, Elghareeb, Nourhan, Esmat, Nourhan Ahmed, Fadel, Ahmed, Habater, Abdullah, Hamdy, Heba, Hefni, Amr, Kamal, Marwa, Mohamed Abobakr, Norhan, Sayed, Ahmed, Shaker, Nancy, Taha, Ehab, Tharwat, Hoda, Zakaria, Omar, Abdelmotaleb, Ibrahem, Al-Dhufri, Ali, Al-Himyari, Hamza S., El sheikh, Enas, Eldmaty, Asmaa, Elkhalawy, Aya, M.Elkhashen, Ahmed, Magdy, Kithara, Mostafa, Safa, Sadia, Habib Doutoum, Saleh, Mohamed mahmoud, Samir, Dina, Yahia Mohamed Ali, Mohamed, A. Nassar, Mahmoud, Abdelhady, Samar, Abdelrazek, Aly, Abdelsalam, Israa, El-Sawy, Aya, Essam, Eman, Gadelkarim, Mohamed, Ghaly, Khaled, Hassabalnaby, Mohamed, Masarani, Rana, Mohamed Shaaban, Nourhan, Sabry, Ahmed, Salem, Menatalla, Soliman, Nourhan Akram, Zahran, Diaaaldin, Abou El.soud, Moustafa Ramadan, Badr, Esraa Tarek, Borham, Hala, Elmeslemany, Nehal, Elsayed, Mohammad, Elsherif, Fawzia, Eslam, Sara, Gaber, Gehad, Ibrahim, Sondos, Kamh, Yara, Mahmoud, Abdelrahman, Mohamed, Shimaa gamal, Morshedy, Eman, Omar, Cinderella, Salem Soliman, Fatima, Abdelkawy, Shaza, Abdelmohsen, Naglaa, Abdelshakour, Mahmoud, Dahy, Ahmed, Gamal, Norhan, Gamal, Mohammed, Hasan, Ahmad, Hetta, Helal, Mousa, Nehad, Omar, Mohamed, Rabie, Somia, Saad, Mahmoud, Saleh, Bakeer, Sayed Mohamed, Marwa, Shawqi, Muhammad, Abdelhady Mousa, Heba, Alnoury, Mostafa, Elbealawy, Mohamed, Elshafey, Ahmed, Essam Ibrahim El Desouki Muhammad Ahmed, Muhammad, Ghonaim, Mennatullah, Hgag, Fawzy, Ibrahim, Mohamed, Morsy, Mahmoud, Reda Loaloa, Mohamed, Refaat, Ahmed, Samir, Hadeer, Shahien, Fatma, Sobhy, Mohamed, Sroor, Fathy, Abdellatif, Esraa, Adel, Marina, Afifi, Amr Abdelghani, Afifi, Eman, Antaky, Marco, Dawoud, Amr, El Zoghby, Naira, El-remaily, Amira, Elzanfaly, Ali Abdelazez, Gadallah, Ahmed, Gamal, Fatma Alzahraa, Hashem, Omar, Medhat Youssef, Shrouk, Muhammad Attyah, Aliaa, Munir, Malak, Shazly, Omar, Taha, Esraa, Wilson, Karim, Adel, Sawsan, Ali, Asmaa, Eid, Esraa, Elhelow, Esraa, Elmahdy, Marwa, Elshatby, Bassant, Hossam el-din Zakaria, Amany, Hossny, Ahmad, Ibrahim, Eman, M.Yonis, Ahmed, Metwalli, Maram, Yousry, Basant, Zid, Esraa, A Yacoub, Mina, Abdelhakim, Ahmed, Abouelsoad, Nervana, Alkhatib, Mo'min, Ashraf, Ahmed, Ashraf, Alaa, Elazab, Yasmin, Elfanty, Mahmoud, Elkabir, Osama, Elsayed, Mai, Elshimy, Ahmed, Elsobky, Hager, Eskander, John, Gad, Ahmed, Hamsho, Ward, Khaled Abdelwahed, Noura, Magdy, Menna, Moharam, Dalia, Osama, Abeer, Ramadan, Shereen, Roum, Radwa, Sayed, Taqwa, Shehada, Tarneem, Zidan, Ahmed Mohy, Abbas, Khalid, Ali, Amr, Attia, Mohamed, Balata, Mohamed, El Nakeeb, Ayman, Elewaily, Mohamed Ibrahim Elsayed, Elfallal, Ahmed, Elfeki, Hossam, Elkhadragy, Ahmed, Emile, Sameh, Ezzat, Helmy, Hosni, Hasnaa, Mansour, Islam, Omar, Waleed, Othman, Gehad, Sadek, Kareem, Shalaby, Mostafa, Shehab-Eldeen, Noura, Anas khalifa, Rawda, Badr, Helmy, Eldeep, Mostafa, Eldeep, Ahmed, Eldoseuky mohammed, Amany, Khallaf, Salwa, Magdy Hegazy, Eman, Mahmoud, Rokia, Mikhail, Pola, Morsi, Mahmoud, Mowafy, Sara, Raafat, Dina, Safy, Amina, Sera, Marwa, Sera, Ahmed shible, AbdAllah, Mostafa Salim Mohamed, Abdelkader, Muhammad, Abdou, Abdulrahman Osama, Ahmed, Ahmedgaber, Gaafar, Shireen, Ibrahim negm, Fatma, Lapic, Mina, Maher, Ahmed, Mahmoud, Hagar, Mostafa, Ahmed, Samir, Mohamed, Samy, Fatma, Semeda, Nourhan, Shalaby, Hind I., El-taweel, Alaa, Galal Elnagar, Ahmed, Hemidan, Ahmed Gamal, Hussein, Mohamed, Kandil, Ahmed.A., Moawad, Mf, Nasser Hamamah, Ayat Allah, Soliman, Mostafa, Abdelkhalek, Mohamed, Abdelmaksoud Tawakel, Noura, Abdelwahed, Ahmed Mohamed, Abdou, Alrawy, Atallah, Khalid, Elsherbeny, Mohammed Yasser, Emara, Eman, Hamdy, Mohamed, Hamdy, Omar, Haron, Amira, Ismail, Salma, Metwally, Islam Hany, Mohamed Hamed Elgaml, Nihal, Nassar, Ahmed, Refky, Basel, Sadek, Mirna, Saleh, Mahmoud, Yunes, Asmaa, Zakaria, Mai, Zuhdy, Mohammed, Fayed, Notila, Mohammed, Mohammed Mustafa Hassan, Kütner, Sander, Melnik, Priit, Seire, Indrek, Ümarik, Toomas, Ainoa, Eppu, Eerola, Verner, Koppatz, Hanna, Koskenvuo, Laura, Sallinen, Ville, Takala, Sini, Katunin, Jevgeni, Turunen, Arto, Christou, Niki, Mathonnet, Muriel, Lavoue, Vincent, Nyangoh Timoh, Krystel, Soulabaille, Lucie, Lesourd, Romain, Merdrignac, Aude, Sulpice, Laurent, André, Benoît, Chantalat, Elodie, Vaysse, Charlotte, Dousset, Bertrand, Gaujoux, Sebastien, Martin, Gregory, Clonda, Octavian, Juodis, Domantas, Kienle, Klaus, Mravik, Andras, Palmer, Samuel, Szabadhegyi, Gabor, Agbeko, Anita Eseenam, Gyabaah, Solomon, Gyamfi, Frank Enoch, Naabo, Nuhu, Owusu senior, Atta, Yorke, Joseph, Owusu, Frank, Abantanga, Francis, Anyomih, Theophilus Teddy Kojo, Muntaka, Abdul-Jalilu Mohammed, Owusu Abem, Emmanuel, Sheriff, Mohammed, Wondoh, Paul M., Balalis, Dimitrios, Korkolis, Dimitrios, Gkiokas, Georgios, Pantiora, Eirini, Theodosopoulos, Theodosios, Ioannidis, Argyrios, Konstantinidis, Konstantinos, Konstantinidou, Sofia, Machairas, Nikolaos, Paspala, Anna, Prodromidou, Anastasia, Chouliaras, Christos, Papadopoulos, Konstantinos, Baloyiannis, Ioannis, Mamaloudis, Ioannis, Tzovaras, George, Akrida, Ioanna, Argentou, Maria-Ioanna, Germanos, Stylianos, Iliopoulos, Evangelos, Maroulis, Ioannis, Skroubis, George, Theofanis, George, Chatzakis, Christos, Ioannidis, Orestis, Loutzidou, Lydia, Karathanasis, Panagiotis, Michalopoulos, Nikolaos, Theodoropoulos, Charalampos, Theodorou, Dimitrios, Triantafyllou, Tania, Garoufalia, Zoe, Hasemaki, Natasha, Kontos, Michalis, Kouraklis, Gregory, Kykalos, Stylianos, Liakakos, Theodore, Mpaili, Eustratia, Papalampros, Alexandros, Schizas, Dimitrios, Syllaios, Athanasios, Tampaki, Ekaterini Christina, Tsimpoukelis, Antonios, Antonopoulou, Maria Ioanna, Deskou, Eirini, Manatakis, Dimitrios K., Papageorgiou, Dimitrios, Zoulamoglou, Menelaos, Anthoulakis, Christos, Margaritis, Michalis, Nikoloudis, Nikolaos, Campo, Veronica, Ceballos, André, Flores, Mario-Andrés, Giron, Waleska, Ko, Donghyun, Martinez, Gabriel, Rivera Lara, Verónica, Rueda, Nataly, Sanchez, Andres, Tejeda Garrido, Jorge Carlos Guillermo, Alvarez Rivera, Alvaro Eduardo, Bamaca Ixcajoc, Elvis Benjamin, Barreda Zelaya, Lilian Elizabeth, Chacòn-Herrera, Patricia, Corea Ruiz, Ligia Margarita, Echeverria-Davila, Guillermo, Garcia, Mario, García, Danilo, Gutiérrez Mayen, Edgar Fernando, José, Noriega, Mazariegos, Nery, Méndez, Diego, Paniagua Espinoza, Michael, Bardos, David, Benke, Marton, Illes, Kristof, Kokas, Balint András, Szabó, Réka, Appukuttan, Akhila, Asok, Anjitha, D.k, Vijaykumar, Malik, Kapil, Ravishankaran, Praveen, Tapkire, Ritesh, Moorthy, Guru, Abraham, Joyner, Muthuvel, Ramesh, Alapatt, John, Kattepur, Abhay, Pareekutty, Nizamudheen, Garod, Mebanshanbor, Harris, Caleb, Wanniang, Cliff, Gupta, Ashish, Nehra, Deepak, Parshad, Sanjeev, Acharya, Rajgopal, Badwe, Rajendra, Bhandare, Manish, Jain, Urvashi, Kirti, Karishma, Nair, Nita, Shrikhande, Shailesh, Thakkar, Purvi, Anandan, Premkumar, C S, Archana, Holenarasipur Narasannaiah, Arun, Jagarlamudi, Tejaswi, M R, Rashmi, Manangi, Mallikarjuna, Raghavendra, Abhishek, Rao, K. Seshagiri, S, Vinay, Sajjan, Vinay, Shenoy, Aneesh, Shivashankar Chikkanayakanahalli, Santhosh, Tharanath, Kavya, V, Sushmita, Adidharma, Peter, Agarwal, Raksheeth, Anggita Gultom, Phebe, Arifin, Ghafur Rasyid, Billy, Matthew, Elfizri, Zatira, Fahira, Alessa, Felicia, Devi, Gunardi, Triana Hardianti, Johanna, Nadya, Nugrahadi, Nadia Rahmadiani, Panigoro, Sonar Soni, Rahmayanti, Siti, Sihotang, Retta Catherina, Brata, Santi Yuanita, Winoto, Hadi, Barati, Nastaran, Karami, Manoochehr, Khorshidi, Hamidreza, Naderifar, Homa, Abdulla, Mazin A., Coleman, Maggie, Doherty, Ronan J, Hannon, Rob, Murphy, Brenda, Stakelum, Aine, Winter, Des, Aljohmani, Lylas, Farnan, Richard, Seldon, Yeshey, Tan, Tanna, Varghese, Shriya, Alherz, Mohammad, Ather, Muaaz, Bajilan, Mohammad, Graziadei, Vivien, Pilkington, Isobel, Quidwai, Omar, Ridgway, Paul, Shiwani, Haaris, Tahir, Abd al-Rahman, Blunnie, Eimear, Burke, Daniel, Kennedy, Niall, Macdonagh, Kate, O'Neill, Maeve, Rooney, Siobhan, Falco, Giuseppe, Ferrari, Guglielmo, Mele, Simone, Nita, Gabriela Elisa, Ugoletti, Lara, Zizzo, Maurizio, Confalonieri, Gianmaria, Pesenti, Giovanni, Tagliabue, Fulvio, Baronio, Gianluca, Ongaro, Deborah, Pata, Giacomo, Compagnoni, Bruno, Salvadori, Renato, Taglietti, Lucio, D'Alessandro, Nicola, Di Lascio, Pierpaolo, Pascale, Giovanni, Bortolasi, Luca, Campagnaro, Tommaso, Carlini, Massimo, Lisi, Giorgio, Lombardi, Davide, Pedrazzani, Corrado, Spoletini, Domenico, Turri, Giulia, Violi, Paola, Altomare, Donato Francesco, Aquilino, Fabrizio, Musa, Nicola, Papagni, Vincenzo, Picciariello, Arcangelo, Vincenti, Leonardo, Andreotti, Dario, Occhionorelli, Savino, Tondo, Matteo, Basso, Stefano Maria Massimiliano., Ubiali, Paolo, Cirelli, Riccardo, Maino, Marco Enrico Mario, Piozzi, Guglielmo Niccolò, Picone, Emanuele, Scaramuzzo, Rosa, Sinibaldi, Giovanni, Amendola, Alfonso, Anastasio, Lorenzo, Bucci, Luigi, Caruso, Emanuele, Castaldi, Antonio, Di Maso, Sara, Dinuzzi, Vincenza Paola, Esposito, Giovanni, Gaudiello, Maria, Giglio, Mariano Cesare, Greco, Paola Antonella, Luglio, Gaetano, Manfreda, Andrea, Marra, Ester, Mastella, Federica, Pagano, Gianluca, Peltrini, Roberto, Pepe, Vincenzo, Sacco, Michele, Sollazzo, Viviana, Spiezio, Giovanni, Cianchetti, Ettore, Menduni, Nunzia, Carvello, Michele Maria, Di Candido, Francesca, Spinelli, Antonino, Corsi, Fabio, Sorrentino, Luca, Marino, Fabio, Asti, Emanuele Luigi Giuseppe, Bonavina, Luigi, Rausa, Emanuele, Asta, Martina, Belli, Andrea, Bianco, Francesco, Cervone, Carmela, Delrio, Paolo, Falato, Armando, Fares Bucci, Andrea, Guarino, Rita, Pace, Ugo, Rega, Daniela, De Luca, Emilia, Gallo, Gaetano, Sammarco, Giuseppe, Sena, Giuseppe, Vescio, Giuseppina, Santandrea, Letizia, Ugolini, Giampaolo, Zattoni, Davide, Chetta, Nicola, Logrieco, Gaetano, Vanella, Serafino, Garulli, Gianluca, Zanini, Nicola, Bondurri, Andrea, Cammarata, Francesco, Colombo, Francesco, Foschi, Diego, Lamperti, Giulia Maria Beatrice, Maffioli, Anna, Sampietro, Gianluca Matteo, Yakushkina, Al'ona, Zaffaroni, Gloria, Cicuttin, Enrico, Sibilla, Maria Grazia, Impellizzeri, Harmony, Inama, Marco, Moretto, Gianluigi, Mochet, Sylvie, Ponte, Elisa, Usai, Antonella, Mancini, Stefano, Sagnotta, Andrea, Solinas, Luigi, Bolzonaro, Elisa, Tamini, Nicolò, Curletti, Gianluca, Galleano, Raffaele, Malerba, Michele, Campanella, Sofia, Cocorullo, Gianfranco, Colli, Francesco, De Marco, Paolino, Falco, Nicolò, Fontana, Tommaso, Kamdem Mambou, Leonel jospin, La Brocca, Antonella, Licari, Leo, Randisi, Brenda, Rizzo, Giovanna, Rotolo, Giulia, Salamone, Giuseppe, Tutino, Roberta, Venturelli, Paolina, Malabarba, Stefano, Sgrò, Alessandro, Vella, Ivan, Cirillo, Bruno, Crocetti, Daniele, De Toma, Giorgio, Lapolla, Pierfrancesco, Mingoli, Andrea, Sapienza, Paolo, Belvedere, Angela, Bianchini, Stefania, Binetti, Margherita, Birindelli, Arianna, Tonini, Valeria, Podda, Mauro, Pulighe, Fabio, De Rosa, Michele, Bono, Lorenzo, Borghi, Felice, Geretto, Paolo, Giuffrida, Maria Carmela, Lauro, Corrado, Marano, Alessandra, Pellegrino, Luca, Salusso, Paola, Sasia, Diego, Campanelli, Michela, Realis Luc, Alberto, Trompetto, Mario, Cardia, Roberto, Cillara, Nicola, Giordano, Antonio Nicola, Costanzo, Antonio, Giovilli, Mario Alessandro, Turati, Luca, Canonico, Silvestro, Sciaudone, Guido, Selvaggi, Francesco, Selvaggi, Lucio, Albsoul, Nader, AlBsoul, Ahmad, Alkhatib, Ala'a Aldeen, Alsallaq, Osama, Amarin, Justin Z., Ayoub, Rami, Bsisu, Isam, El Muhtaseb, M S, Jabaiti, Mohammad, Melhem, Jamal, Qwaider, Yasmeen Z., Salameh, Mohammad Hasan, Suleihat, Ahmad, Suradi, Haya H., Alammarin, Mohammad, Aljaafreh, Almoutuz, Bani hani, Mohammad, Bani hani, Zeina, Bani Hani, Farah, Fahmawee, Toqa, Hamouri, Shadi, Katanani, Cyrine, Tawalbeh, Ra'fat, Tawalbeh, Tamara, Zawahrah, Hassan, Abou Chaar, Mohamad K., Abusalem, Lana, Al-Masri, Mahmoud, Al-Najjar, Hani, Barghuthi, Lutfi, Ahmed, Zahra, Maulana, Adnan, Ngotho, Omar, Kamau, Charbel, Stanley Mwenda, Aruyaru, Bosire, Fridah, Mwachiro, Elizabeth, Parker, Robert, Simel, Ian, Sylvester, Kimutai, Althini, Abdulmunem Ahmed Mustafa, Elbarouni, Sofian, Elbeshina, Aya Elseed, Gwea, Ahmed, Malek, Ans, Masoud Farag, Wedad Albashir, Abdalei, Abdulwahab, Abdel Malik, Abu Baker, Abo-khammash, Areej, Abuhlaiga, Ma'aly, Adnan, Nour, Albaggar, Marwa, Alfitory, Asma, Aljanfi, Asma, Almuzghi, Fakhruddin, Altumei, Zohoor, Alzabti, Fatima, Ashoushan, Hana, Assalhi, Mohamed, Azzubia, Joma, Bnhameida, Sondos, Delhen, Malik, Elshafei, Houssein, Elteir, Hana, Esbaga, Fatima, Gobbi, Abdel Aziz, Hamouda, Fatma, Hilan, Hamdan, Ismail, Rania, Jebran, Fieruz, Kasbour, Muataz, Maderi, Galia, Mohammad, Saja, Mohammed, Burooj, Murtadi, Habib, Mustafa, Hamassat, Rajab, Mohamed, Trenba, Sarah, Wafaa, Mariam, Al Sagheir, Eman, Almigheerbi, Alabas, Alzahaf, Ahmed, Bahroun, Sumayyah Ghayth, Ben Dallah, Najah, Elshaibani, Mahmoud, Eswaye, Haitem, Karar, Maha, Omar, Samah, Younes, Eman, Younes, Maha, Zreeg, Dafer, Abujamra, Saleh, Ashour, Firas, Elgammudi, Mala, Omar F. Aljadidi, Wesal, Saddouh, Enas, Sharif, Randa, Alabuzidi, Aya, Alwerfally, AbdulMawlay, Aribi, Sarra, Bibas, Fatma, Elfaituri, Taha, Elhajjaji, Yasmine, Khaled, Ala, Khalil, Wegdan, Layas, Tesneem, Soula, Enas, Tarek, Ahmed, Abu hallalah, Muad fathi khalleefah, Ahmed, Hazem Abdelkarem, Alsharef, Tagwa, Ben Saoud, Abdulsalam Ali, El Gharmoul, Tasnim, Elhadi, Ahmed, Elrais, Safa, Shebani, Abdulhalim, Zarti, Heba, Zeiton, Asaid, Ambrazevicius, Marijus, Kaselis, Nerijus, Stakyte, Migle, Aliosin, Oleg, Cizauskaite, Agne, Dailidenas, Sarunas, Eismontas, Vitalijus, Kybransiene, Migle, Nutautiene, Vitalija, Samalavicius, Narimantas, Simcikas, Dainius, Slepavicius, Algirdas, Tamosiunas, Albinas, Ubartas, Nerijus, Zeromskas, Paulius, Bradulskis, Saulius, Dainius, Edvinas, Juočas, Juozas, Kubiliute, Egle, Kutkevičius, Juozas, Opolskis, Aurimas, Parseliunas, Audrius, Subocius, Andrejus, Virbickaite, Egle, Zuikyte, Diana, Bogusevicius, Algirdas, Buzaite, Kristina, Čepuliené, Daiva, Cesleviciene, Ieva, Cesna, Vaidotas, Gribauskaite, Jolanta, Ignatavicius, Povilas, Jokubauskas, Mantas, Liugailaitè, Monika, Margelis, Ernest, Mazelyte, Ruta, Pankratjevaitè, Lina, Pažusis, Matas, Rackeviciute, Agne, Saladyte, Justina, Škimelytè, Monika, Šlenfuktas, Vygintas, Sudeikyte, Monika, Tamelis, Algimantas, Vanagas, Tomas, Žumbakys, Žygimantas, Atkociunas, Aivaras, Dulskas, Audrius, Kuliavas, Justas, Birutis, Justas, Paškevičius, Sigitas, Šatkauskas, Mindaugas, Danys, Donatas, Jakubauskas, Matas, Jakubauskiene, Lina, Kryzauskas, Marius, Lipnickas, Vytautas, Makūnaitè, Gabija, Rasoaherinomenjanahary, Fanjandrainy, Rasolofonarivo, Herizo, Samison, Luc Hervé, Banda, Bitiel, Msosa, Vanessa, Ahmad Izzuddin, Ahmad Imran, Das, Andre, Gan, Ying Yee, Shong Sheng, Tan, Siaw, Jia yng, Ab Rahim, Mohd Fadliyazid, Abang Jamari, Dyg Zahratul Hamrak, Che Husin, Nurfariza, Kamarulzaman, Muhd Yusairi, Lim, Yi Ping, Mohamed Kamil, Nil Amri, Mohd Hassan, Mohd Razeen, Mohd Sahid, Saidah, Mustafa, Johari, Ng, Elaine Hui Been, Wan Khazim, Wan Khamizar, Chang Ern, Ng, Lingeshan, P.g., Sulaiman, Syariz Ezuan, Ang, Sue Ean, Bin Mohamad Sithik, Muhammad Navid, Cheong, Yih Jeng, Deva Tata, Mahadevan, Jia Xian, Law, Kadravello, Aravinthan, Koh, I-Ern, Ng, Li-Yen, Ng We Yong, Yuki Julius, Palayan, Kandasami, Sam, Chi Xuan, Siow Jin, Phuah, Tan Ern Hwei, Jeremy, Tang, Yita, Ter, Alvin Zubin, Wong, Michael Pak-Kai, Zakaria, Andee Dzulkarnaen, Zakaria, Zaidi, Henry, Fitjerald, Kalaiselvan, Thyivya, Abd Karim, Muhammad Fairuz Shah, Abdul Aziz, Mohamed Rezal, Abdul Aziz, Nora, Khong, Tak Loon, Lau, Peng Choong, Lim, Hiong Chin, Roslani, April Camilla, Seak, Jonathan Chen Ken, Wong, Sui-Weng, Wong, Lai Fen, Yeen Chin, Leow, Anyanwu, Mercy Chinemerem, Busuttil, Zachary, Calleja, Thomas, Chircop, Kurt Lee, Cutajar, Ruth, Dimech, Andrew Michael, Galea, Joseph, Gascon Perai, Kiara, Gatt, Ruth, Kelman, Lisa, Micallef, Elizabeth, Nwolu, Favour, Sammut, Kim, Thompson, Joanna, Warwicker, Sean, Zammit, Matthew, Cordera, Fernando, Cruz González, Efraín, Sánchez-García, Jorge, Barbosa Camacho, Francisco José, Barrera López, Francisco Javier, Zuloaga Fernandez del Valle, Carlos Jose, Acosta, Eric, González Espinoza, Iván Romarico, Moreno, Perla, Cortes-Flores, Ana Olivia, Fuentes Orozco, Clotilde, Gonzalez Ojeda, Alejandro, Corro Díaz González, Samantha, Martinez, Laura, Mosqueda Amador, Bonifacio, Novoa, Armando, Olazo Espejo, Dennet Arturo, Jimenez, Alejandro, Lopez Rosales, Federico, Vanoye, Elva Gabriela, Garcia Gonzalez, Luis Alberto, Miranda-Ackerman, Roberto Carlos, Solano-Genesta, Manuel, Alvarez-Cano, Alethia, Romero-Garza, Hector Hugo, Medina-Franco, Heriberto, Mejía-Fernández, Lorelí, Salgado-Nesme, Noel, Vergara-Fernandez, Omar, Gutiérrez-Mota, Guadalupe Montserrat, Hernandez Vera, Francisco Xavier, Llantada Lopez, Anabella, Morgan Villela, Gilberto, Ramirez Padilla, Felipe de Jesus, Tapia Marin, Walezka, Martínez Maldonado, Mónica, Sánchez Suárez, Ramses, Troche, José Manuel, Benyaiche, Chaymae, Outani, Oumaima, Amine, Souadka, Benkabbou, Amine, Majbar, Anass Mohammed, Mohsine, Raouf, Rafik, Ali, Oung, Thida, Tin, Moe Moe, Plarre, Philipp, Alberga, Anna, Sluiter, Nina, Tuynman, Jurriaan, Blok, Robin, Cömert, Didem, Hompes, Roel, Kalff, Marianne, Stellingwerf, Merel Elisabeth, Tanis, Pieter, van Berge Henegouwen, Mark, van Praag, Elise Maria, Wisselink, Daan, Gerhards, Michael, Lopes Cardozo, Josephine, Westerduin, Emma, de Jonge, Joske, van Geloven, Aaw, van Schilt, Kaz, den Boer, Frank, Stoots, Simone, Vlek, Stijn, Adams, Jamie, Al-Busaidi, Ibrahim S., Budd, Gabrielle, Choi, Seung il, Chu, Michael Jen Jie, Ganugapati, Anurag, McKinstry, Lucy, Pascoe, Rebecca, Richards, Simon, Rosser, Kenrick, Stevenson, Annie, White, Rebecca, Farik, Shebani, Kwun, Jin, Murad, Ahmed, Cowan, Sarah, Hall, Timothy, Hayton, Michael, Malam Sani, Laminou, Oumarou Garba, Souleymane, Amadou Magagi, Ibrahim, Habou, Oumarou, Aliyu, Halima, Daniyan, Muhammad, Sholadoye, Tunde T., Abdullahi, Lawal, Anyanwu, Lofty-John, Mohammad Mohammad, Aminu, Muhammad, Abubakar Bala, Sheshe, Abdurrahman Abba, Suleiman, Ibrahim, Adesina, Alaba, Awolowo, Ajibola, Onuoha, Clement, Salami, Omotayo, Taiwo, Ogechukwu, Taiwo, Agboola, Kache, Stephen, Makama, Jerry Godfrey, Sale, Danjuma, Abiola, Olajide, Ajao, Akinlabi, Ajiboye, Anthony, Etonyeaku, Amarachukwu, Olaogun, Julius, Adebanjo, Ademola, Adesanya, Opeoluwa, Afolayan, Michael Olatunji, Balogun, Olanrewaju, Makanjuola, Ayomide, Nwokocha, Samuel, Ojewola, Rufus Wale, Olajide, Thomas Olagboyega, Aderounmu, Adewale, Adesunkanmi, Abdul-Rashid, Agbakwuru, Augustine, Akeem Aderogba, Adeleke, Alatise, Olusegun Isaac, Arowolo, Olukayode, Lawal, Oladejo, Mohammed, Tajudeen, Ndegbu, Chinedu, Olasehinde, Olalekan, Wuraola, Funmilola, Akinkuolie, Akinbolaji, Mosanya, Arinzechukwu, Ayandipo, Omobolaji, Elemile, Peter, Lawal, Taiwo Akeem, Ali SANI, Samuel, Garba, Stephen, Hauwa SANI, Rebecca, Olori, Samson, Onyebuashi, Henry, Umoke, Ifeanyi, Adenuga, Adedire, Adeyeye, Ademola, Habeeb, Olufemi, Lawal, Bashir, Nasir, Abdulrasheed, Aahlin, Eirik Kjus, Kjønås, Didrik, Myrseth, Elisabeth, Abbasy, Jibran, Alvi, Abdul, Saleem, Omair, Afzal, Asma, Nazir, Anam, Farooq, Muhammad, Liaqat, Ayesha, Naqi, Syed Asghar, Raza, Ali, Sarfraz, Muzna, Sarwar, Muhammad, Banglani, Muntaha, Munir, Ambreen, Sehrish, Rahmat, Ayub, Bushra, Sayyed, Raza, Altaf, Amna, Ayub, Saima, Saeed, Komal, Syed, Bilal, Akbar, Sana Amir, Anwer, Abdul Wahid, Khan, Ruqayya Naheed, Khan, Amina Iqbal, Khattak, Shahid, Mohtasham, Sameen, Parvaiz, Muhammad Asad, Syed, Aamir Ali, Ansari, Abdul Basit, Shahzad, Noman, Khaliq, Tanwir, Rashid, Isbah, Waqar, Shahzad Hussain, Abu Al-saleem, Hasan, Abu Alqumboz, Amjad, Alqadi, Mohammad, Amro, Adham, Assa, Rawan, Awesat, Eman, Ayyad, Rawan, Hammad, Mohammed, Haymony, Ayat, Hijazi, Bassel, Hmeidat, Bara, Lahaseh, Rowaa, Qawasmi, Aseel, Rajabi, Alaa, Shehada, Mohammed, Shkokani, Sundus, Yaghi, Yasmine, Yaghi, Nadine, AlZohour, Mohammad, Farid, Mohammad, Habes, Yousef Mahmoud, Juba, Wesam, Nubani, Yanal, Rabee, Abdelrahman, Sa'deh, Mohammad, Abed, Saeed, Al basos, Iyad, Alswerki, Mohammad, Ashour, Dina, Awad, Israa, Diab, Samar, El Jamassi, Alaa, El-Kahlout, Sahar, Elhout, Somaya, Hajjaj, Ahmed N K, Hasanain, Doaa, Nabil hajjaj, Baraa, Obaid, Mohammed, Saikaly, Eman, Salhi, Ahmed, Al-Tammam, Hiba, Almasri, Murad, Baniowda, Muath, Beshtawi, Doha, Horoub, Ali, Misk, Rami, Mohammad, Bayan, Qasrawi, Rami, Sholi, Tasnim, Abu-Nimeh, Samar, Abu-srour, Abrar, Abukhalaf, Sadi A., Adawi, Samer, Alsalameh, Barah, Ayesh, Kholoud, Elqadi, Muawiyah, Hammouri, Ahmad, Karim Mustafa, Fatima, Marzouqa, Natalie, Melhem, Shatha, Miqdad, Dima, Mohamad, Balqees, Rawhi, Mhammed, Abu Ahammala, Ayman B., Abu Ataya, Ahmed, Abu Jayyab, Israa, Al-Shwaikh, Samar, Alagha, Othman, Alasttal, Mohammed, Awadallah, Haneen, Elblbessy, Mahmood, Fares, Jehad, Jarbou, Akram, Mahfouz, Ibtisam, Albahnasawi, Moath A., Abo mahadi, Asmaa', Abuelhatal, Hasan, Abuelqomboz, Ayham, Almoqayyad, Abdelrahman, Alwali, Abdallah, Balaawi, Reem, Hamouda, Mahmoud, Humeid, Mohammed, Jedyan, Abdullah, Mahmoud Abu hamam, Tasneem, Matar, Ghadeer, Salem, Ali, Samra, Tahani, Shaheen, Nureddin, Shihada, Karam, A.Nemer, Ayoob, Abu Al Amrain, Mahmoud, Abu Alamrain, Abdulwhhab, Abu Jamie, Najlaa, Abu-Rous, Mohammed R., Alfarra, Nada, AlTaweel, Mohammed, Alwhaidi, Noor, Hamed, Ramadan, Saqqa, Bader, Shaheen, Ahmad, Aljaber, Dana, Aljaberi, Loay, Alwaheidi, Malak, Jawaada, Assef, Khaldi, Hani, Qahoush, Rami, Qari, Jalil, Saadeh, Rana, Salim, Ahlam, Yacoub, Aseel, Abbas, Abbas, Abu shua'ib, Rana, Abu Zainah, Baraa, AbuSirrees, Mahmoud, Babaa, Basheer, Barhoush, Ola, Belal qadomi, Asef, Daraghmeh, Laith, Haji, Reema, Khatatbeh, Alaa, Khatib, Lana, Qarariah, Salsabeel, Quzmar, Yara, Safadi, Khalil, Salameh, Roqaya, Hassan, Mohammad, Herzallah, Shifaa, Massad, Loai, Nazzal, Ahmed, Nazzal, Ranin, Escobar, Dennis, Machain V, Gustavo Miguel, Rodriguez Gonzalez, Agustin, Chachaima Mar, Jorge Emerson, Chinchihualpa Paredes, Nathaly Olga, Cuba, Vicente, Lopez, Walter, Niquen Jimenez, Maria Milagros, Sanchez Bartra, Nestor Alberto, Sapallanay Ojeda, Olenka, Sequeiros, Diego, Toscano Pacheco, Andrea, Vergara, María, Abarca, Sol, Alcorta, Rodrigo, Borda-Luque, Giuliano, Eusebio Zegarra, Ivan Edward, Luján López, Claudia, Marrufo, Mirella, Mogrovejo, Cinthya, Nomura, Andrea, Rodríguez Angeles, Yamile, Vidal Meza, Maitza Rosario, Zavala, Gabriela, Castillo Arrascue, José Neiser, Hidrogo Cabrera, Jomara Caroline, Larrea vera, José Julio Mariano, Osorio, Miguel, Ylatoma Díaz, Edgar Alcides, Fontanilla, Mark Anthony, Fuentes, Joseph Roy, Salazar, Anna Leah, Dominguez, Genieve, Lopez, Marc Paul, Macalindong, Shiela, Onglao, Mark Augustine, Ramirez, Arjel, Sacdalan, Marie Dione, Tampo, Mayou Martin, Uy, Gemma Leonora, Mangahas, Jeremiah, Yabut, Kenneth, Cañete, Joannes Paul, Cansana, Bernalynn Eris, Castro, Ernes John, Lipana, Maria Kaiserin, Roxas, Manuel Francisco, Zara, Vlu Jean, Chroł, Maciej, Franczak, Paula, Orłowski, Michał, Budzyński, Piotr, Budzyński, Andrzej, Bury, Pawel, Czerwińska, Agata, Dworak, Jadwiga, Dziedzic, Jacek, Kisielewski, Michał, Kulawik, Jan, Lasek, Anna, Małczak, Piotr, Migaczewski, Marcin, Pędziwiatr, Michał, Pisarska, Magdalena, Radkowiak, Dorota, Rubinkiewicz, Mateusz, Rzepa, Anna, Skoczylas, Tomasz, Stanek, Maciej, Truszkiewicz, Katarzyna, Wierdak, Mateusz, Winiarski, Marek, Zarzycki, Piotr, Zub-Pokrowiecka, Anna, Kowalewski, Piotr, Roszkowski, Rafał, Walędziak, Maciej, Tomé, Miguel, Patrocinio, Sara, Guerreiro, Ines, Almeida, Filipe, de Sousa, Xavier, Monteiro, Nuno, Costa Santos, Maria Teresa, de Oliveira, Daniela, Lopes Serra, Marta, Morgado, Daniela, Neves, Christian, Oliveira, Ana Carolina, Pimentel, Alice, Silva, Sofia, Carvalho, Márcia, Carvalho, Lúcia, Magalhães, Joana, Matos, Leonor, Monteiro, Tânia, Ramos, Carlota, Santos, Vanessa, Barbosa, José, Costa-Maia, Jose, Devezas, Vítor, Fareleira, Ana, Fernandes, Cristina, Gonçalves, Diana, Mora, Henrique, Morais, Marina, Silva de Sousa, Fabiana, Catarino Santos, Sara, Logrado, Ana, Tojal, André, Amorim, Edgar, Cunha, Miguel F., Fazenda, Ana, Melo Neves, João Pedro, Sampaio da Nóvoa Gomes Miguel, Inês Isabel, Veiga, Diogo, Azevedo, José, Cardoso Louro, Hugo, Leite, Mariana, Bairos Menezes, Maria, Gama, Bárbara, Brito, Diana, Cruz Martins, Marta Cristina, Graça e Magalhães, André, Longras, Ana Catarina, Lourenço, Rita, Matos, Diana, Castro, Luis, Policarpo, Filipa, Romano, Joana, Monteiro, Cristina, Pinto, Diogo, Duarte, Marina, Fortuna Martins, Sónia, Oliveira, Mariline, Galvão, Diogo, Martins, Lisandra, Silva, Anaisa, Taranu, Viorel, Vieira, Bárbara, Neves, Jessica, Oliveira, Simone, Ribeiro, Hugo, Cinza, Margarida, Felix, Rosa, Machado, Arnaldo, Oliveira, Joana, Patrício, Joana, Pedroso de Lima, Rita, Pereira, Mário, Rocha Melo, Miguel, Velez, Cristina, Abreu da Silva, Alberto, Claro, Mariana, Costa Santos, Daniel, Ferreira, Andreia, Capote, Hugo, Rosado, Daniela, Taré, Filipa, Nogueira, Oriana, Ângelo, Miguel, Baiao, José Miguel, Guimarães, Andreia, Marques, João, Nico Albano, Miguel, Silva, Marta, Valente da Costa, Ana, Vieira Caroço, Teresa, Almeida Braga, Sara, Capunge, Ines, Fragoso, Marta, Guimarães, João, Pinto, Bruno, Ribeiro, João, Angel, Miguel, Fialho, Guilherme, Guerrero, Monica, Campos Costa, Filipa, Cardoso, Diogo, Cardoso, Vasco, Alves, Magda, Estalagem, Inês, Louro, Tiago, Marques, Cláudia, Martelo, Rita, Morgado, Miguel, Canotilho, Rita, Correia, Ana Margarida, Martins, Pedro, Peyroteo, Mariana, Gomes, João, Monteiro, Rita, Romano, Manuela, Alves, Daniela Macedo, Peixoto, Rita, Quintela, Catarina, Jervis, Maria João, Melo, Débora, Pacheco, André, Paixão, Valter, Pedro, Vera, Pimenta, Joana, Pimenta de Castro, João, Rocha, Ana, Beuran, Mircea, Ciubotaru, Cezar, Diaconescu, Bogdan, Hostiuc, Sorin, Negoi, Ionut, Stoica, Bogdan, Anokhin, Evgeny, Kuznetsov, Georgy, Oganezov, Giorgi, Paramzin, Fedor, Romanova, Ekaterina, Rutkovskii, Valeryan, Rutkovskii, Vasilii, Shushval, Mikhail, Zabiyaka, Mikhail, Dzhumabaev, Khasan, Ivanov, Valerii, Mamedli, Zaman, Achkasov, Sergey, Balkarov, Artem, Nabiev, Elnur, Nagudov, Marat, Rybakov, Evgeny, Saifutdinova, Karina, Sushkov, Oleg, Joseph, Lule, Ndayishimiye, Isaac, Faustin, Ntirenganya, Mutabazi, Alphonse Zeta, Mvukiyehe, Jean Paul, Nsengimana, Vizir J.P, Uwakunda, Carine, Abbas, Mohammad Monir, Akeel, Nouf, Aljiffry, Murad, Awaji, Kholoud, Farsi, Ali, Jamjoum, Ghader, Khoja, Ahmad, Maghrabi, Ashraf, Malibary, Nadim, Nassif, Mohammed, Saleem, Abdulaziz, Sultan, Abdullah, Tashkandi, Wail, Tashkandi, Hanaa, Trabulsi, Nora, Ba, Mouhamadou Bachir, Diallo, Adja Coumba, Ndong, Abdourahmane, Cuk, Vladica, Janković, Uroš, Koh, Sharon Zhiling, Koh, Frederick, Lee, Kuok Chung, Lee, Kai Yin, Lee, Sean, Leong, Wei Qi, Lui, Su Ann, Prakash, Prajwala, Grosek, Jan, Norcic, Gregor, Tomazic, Ales, Fitchat, Nicolas, Jaich, Robert, Wineberg, Devorah, Koto, Modise Zacharia, Baiocchi, Daniella, Clarke, Damian, Steenkamp, Christina Johanna, Bannister, Sharon, Boutall, Adam, Chinnery, Galya, Coccia, Anna, Dell, Angela, Karjiker, Parveen, Kloppers, Christo, Loxton, Nicholas, Mabogoane, Tumi, Malherbe, Francois, Panieri, Eugenio, Rayamajhi, Shreya, van Wyngaard, Tirsa, Warden, Claire, Madiba, T E, Pillay, Nivashen, Brooks, Savannah, Kruger, Charlise, Van Der Merwe, Lisa Hannah, Gool, Ferhana, Kariem, Maahir, Bougard, Heather, Kariem, Nazmie, Noor, Fazlin, Pillay, Reantha, Steynfaardt, Leandi, González González, Lucía, Marín Santos, José Miguel, Martín-Borregón, Paula, Martínez Caballero, Javier, Nevado García, Cristina, Rodriguez Fraga, Pastora, De Castro Parga, Gonzalo, Fernández Veiga, Maria Pilar, Garrido López, Lucía, Infante Pino, Hugo, Lages Cal, Irene, López Otero, Marta, Nogueira Sixto, Manuel, Paniagua García Señorans, Marta, Rodríguez Fernández, Laura, Ruano Poblador, Alejandro, Rufo Crespo, Erika, Sanchez-Santos, Raquel, Vigorita, Vincenzo, Alonso Batanero, Ester, Asnel, Dorisme, Cifrian Canales, Isabel, Contreras Saiz, Elisa, De Santiago Alvarez, Irene, Díaz Vico, Tamara, Fernandez Arias, Sebastian, Fernández Martínez, Daniel, García Bernardo, Carmen, García Flórez, Luis Joaquín, Garcia Gutierrez, Carmen, García Munar, Manuel, Márquez Zorrilla Molina, Carlos Alberto, Merayo, Marta, Michi Campos, José Luis, Moreno Gijon, Maria, Otero-Diez, Jorge L., Rodicio Miravalles, Jose Luis, Solar-Garcia, Lorena, Suárez Sánchez, Aida, Truan, Nuria, Alejandre Villalobos, Cristina, Caballero Díaz, Yurena, Jimenez, Marta, Montesdeoca, Dacil, Navarro-Sánchez, Antonio, Vega, Victor, Beltrán de Heredia, Juan, Gómez, Zahira, Jezieniecki, Carlos, Legido Morán, Ana Patricia, Montes-Manrique, Mario, Rodriguez-Lopez, Mario, Ruiz Soriano, María, Trujillo Díaz, Jeancarlos, Vazquez Fernandez, Andrea, Argudo, Nuria, Pera, Miguel, Torrent Jansà, Laia, García Domínguez, Melody, Goded, Ignacio, Roldón Golet, Marta, Talal El-Abur, Issa, Utrilla Fornals, Alejandra, Zambrana Campos, Vanesa, Aguilar Martinez, Maria Del Mar, Bosch, Marina, García-Catalá, Luis, Sánchez-Guillén, Luis, Artigau, Eva, Gomez Romeu, Nuria, Julià Bergkvist, David, Espina Perez, Beatriz, Morató, Olga, Olona, Carles, Diéguez, Beatriz, Forero-Torres, Alexander, Losada, Manuel, Gomez-Abril, Segundo, Gonzálvez, Paula, Martinez, Rosario, Navarro Martínez, Sergio, Payá-Llorente, Carmen, Pérez Rubio, Álvaro, Santarrufina Martinez, Sandra, Sebastián Tomás, Juan Carlos, Trullenque Juan, Ramon, Gegúndez Simón, Alberto, Maté, Paloma, Prieto-Nieto, Maria Isabel, Rubio-Perez, Ines, Urbieta, Aitor, Vicario Bravo, Marina, Abelló, David, Frasson, Matteo, Garcia-Granero, Alvaro, Abad Gurumeta, Alfredo, Abad-Motos, Ane, Lucena-de Pablo, Elena, Nozal, Beatriz, Ripollés-Melchor, Javier, Salvachúa, Rut, Ferrero, Esther, Garcia-Sancho Tellez, Luis, Picardo, Antonio L., Rojo López, Jose Alberto, Zorrilla Matilla, Laura Patricia, Cagigas Fernandez, Carmen, Castanedo Bezanilla, Sonia, Estevez Tesouro, José, Fernandez-Diaz, Maria Jose, García Cardo, Juan, Gomez Ruiz, Marcos, Gonzalez-Tolaretxipi, Erik, Jimeno Fraile, Jaime, Poch, Cristobal, Rodriguez-Aguirre, Montserrat, Troche Pesqueira, Noemí, Trugeda-Carrera, Maria Soledad, de la Torre, Javier, Blanco-Colino, Ruth, Espin-Basany, Eloy, Espinosa-Bravo, Martin, Morales Comas, Clara, Reyes Afonso, Eduardo, Rivero Déniz, Joaquín, Siso Raber, Christian, Verdaguer Tremolosa, Mireia, Chandrasinghe, Pramodh, Kumarage, Sumudu, Wijekoon Arachchilage, Nimeshi, Abdalla Ahmed Elkamel, Ahmed, A. Adam, Mohammed, Blomme, Nina, Thorell, Anders, Wogensen, Fredrik, Älgå, Andreas, Ansarei, Dhirar, Celebioglu, Fuat, Heinius, Göran, Nigard, Linda, Pieniowski, Emil, Ahlqvist, Sandra, Björklund, Ida, Frånberg, Andreas, Håkansson, Martina, Adamo, Karin, Franklin, Oskar, Sund, Malin, Wiberg, Rebecca, Andersson, Yvette, Chabok, Abbas, Nikberg, Maziar, Kugelberg, Alexander, Canonica, Claudia, Christoforidis, Dimitrios, Fasolini, Fabrizio, Gaffuri, Paolo, Giuliani, Mauro, Meani, Francesco, Popeskou, Sotirios Georgios, Pozza, Silvia, Wandschneider, Wiebke, Peterer, Lorenz, Widmer, Lukas Werner, Zimmermann, Bernd, Bakoleas, Panagiotis, Chanousi, Iris, Charalampidou, Lydia, Grochola, Lukasz Filip, Heid, Franziska, Ntaoulas, Sotirios, Outos, Michail, Peros, Georgios, Podolska-Skoczek, Hanna, Reinisch, Katharina Beate, Zielasek, Christian, Demartines, Nicolas, Gilgien, Jérôme, Kefleyesus, Amaniel, St-Amour, Pénélope, Toussaint, Arnaud, Alhimyar, Maryam, Alsaid, Bayan, Alyafi, Amr, Alkhaledi, Ahmad, Kouz, Basel, Omarain, Ahmad, Al-Sabbagh, Yusra, Alkhatib, Haya, Sara, Samer, Alhaj, Ahmad, Danial, Aghyad, Kadoura, Lama, Maa Albared, Sarah, Monawar, Yamen, Nahas, Louei, Abd, Barook, Saad, Ahmad, Wakkaf, Habib, Bouzaiene, Hatem, Ghalleb, Montassar, Akaydin, Elif, Akbaba, Ata Cem, Atakul, Onur, Baltaci, Ege, Besli, Sevval, Burgu, Gökçen, Cenal, Ulukan, de Muijnck, Cansu, Demirkaya, Hasan Can, Dogruoz, Alper, Gezer, Zeynep Ipek, Gündoğdu, Yasemin, Kara, Merve, Korkmaz, Hasan Kürşad, Kurtoğlu, Gökalp Kağan, Ozben, Volkan, Ozmen, Berk Baris, Pektaş, Ahmet Murat, Sel, Eda Kübra, Yenidünya, Nilüfer, Bengur, Fuat Baris, Oral, Berke Mustafa, Yozgatli, Tahir Koray, Abdullayev, Seymur, Gunes, Mehmet Emin, Sahbaz, Nuri Alper, Banaz, Tuba, Kargici, Kübra, Kuyumcu, Omer Faruk, Yanikoğlu, Erkan, Yeşilsancak, Merve, Yilmaz, Duygu, Aktas, Melik Kagan, Rencuzogullari, Ahmet, Isik, Arda, Leventoğlu, Sezai, Yalçinkaya, Ali, Yüksel, Osman, Kalayci, Mustafa U, Kara, Yasin, Sarici, Inanc Samil, Akin, Alp, Alemdağ, Gökçe nur, Arslan, Ekin, Baki, Bahadir Emre, Bodur, Muhammed Selim, Calik, Adnan, Candas Altinbas, Bahar, Cihanyurdu, Irem, Erkul, Oğuz, Gül, Burak, Guner, Ali, Köse, Beyza, Semiz, Anil, Sevim, Şule, Tayar, Serkan, Tomas, Kadir, Tüfek, Ozan yavuz, Türkyilmaz, Serdar, Uluşahin, Mehmet, Usta, Arif, Yildirim, Reyyan, Güler, Sertaç Ata, Tatar, Ozan Can, Varol, Ecenur, Kirimtay, Busenur, Uysal, Muhammed, Yildiz, Alp, Kose, Emin, Ciftci, Ahmet Burak, Çolak, Elif, Eraslan, Huseyin, Kucuk, Gultekin Ozan, Yemez, Kürşat, Lule, Herman, Bienfait, Mumbere, Bua, Emmanuel, Okalany, Noella, Basarab, Maksym, Bielosludtsev, Oleksii, Kolhanova, Kateryna, Perepelytsia, Kateryna, Romanukha, Kateryna, Savenkov, Dmytro, Siryi, Stanislav, Tereshchenko, Maksym, Viacheslav, Nezamai, Volovetskyi, Anton, Kebkalo, Andrey, Tryliskyy, Yegor, Tyselskiy, Volodimir, Bruce, Eilidh, Chow, Bing Lun, Iddles, Emma, McGuckin, Sarah, Newall, Nicola, Ramsay, George, Sharma, Parivrudh, Stewart, Caitlin, Wong, Jeremy, Badran, Abdul, Bath, Michael, Belais, Fanny, Butt, Eman, Joshi, Kaustuv, Kapur, Milan, Shaw, Mike, Townson, Adam, Williams, Christopher Yee Khang, Gray, Timothy, Greig, Robert, Husain, Mansoor, Murray, Elspeth, Mustafa, Ahmed, Asif, Ashar, Gokul, Arya, Shah, Max, Akitikori, Mabel Temisanren, Charalabopoulos, Alexandros, Davidson, Sophie, McNally, Sinead, Rupani, Shamil, Juma, Fatema, Mills, Sarah Catherine, Muirhead, Laura, Sellars, Kate, Walsh, Una, Warren, Oliver, Chambers, Alice, Hunt, Richard, Boyce, Stephen, Cornwall, Hannah, Tol, Isabel, Argyriou, Eleftherios Orestis, Eardley, Nicola, Povey, Meical, Aithie, Joanna M S, Irfan, Ahmer, McGuigan, Mari-Claire, Starr, Robert, Warren, Craig Russell, Archibald, Jess, Kirby, Georgia, Kisyov, Ivan, Khoo, Chun Kheng, Lee, Rachel, Photiou, Dana, Davis, Rowan, Prasad, Uday, Yang, P Zichu, Bird, Jonathan, Leung, Edmund, Summerour, Virginia, Currow, Chelise, Kiam, Jianshen, Tan, Gerald Jack Soon, Muthusami, Anitha, Pegba-Otemolu, Ibifunke, Urbonas, Tomas, Nunoo-Mensah, Joseph, Smolskas, Edgaras, Boddy, Alex, Gravante, Gianpiero, Hunter, David, Andrew, David, Koh, Amanda, Thompson, Amari, Adams, Lawrence, Clements, Hollie A, De Silva, Kasun, Ekpete, Ogbonnia, Haque, Seraj, Henderson, Scott, Ibrahim, Bilal, Jayasinghe, Thummini, Livie, Jennifer, Mailley, Keir, Nair, Gopikrishnan, Tan, Daniel, Baggaley, Caitlin, Dawidziuk, Aleksander, Szyszka, Bartosz, Barter, Charlotte, Gandhi, Nirav, Hassell, Karen, Hitchin, Samantha, Kelsall, Jennett, Nagy, Eva, Nessa, Ashrafun, Whisker, Lisa, Yanni, Fady, Ali, Mahmoud, Arora, Deeksha, Hediwattege, Sunanda, Kumarasinghe, Navam, Rathore, Munir, Tennakoon, Athula, Ali Ahmad, Syed Mustafa, Bajomo, Oreoluwa, Nadira, Fahema, Celentano, Valerio, Griffiths, Ewen, Karri, Rama Santhosh, Mak, Jason Kei Chak, Pipe, Michelle, Bhatti, Muhammad Iqbal, Rabie, Mohamed, Boyle, Connor, Hamilton, David, Mihuna, Aishath, Ng, James Chean Khun, Nicholson, Gary, Oliwa, Agata, Pearson, Robert, Rose, Anna, Yong, Shun Qi, Boereboom, Catherine, Hanna, Michael, Walter, Catherine, Greensmith, Thomas Samuel, Mitchell, Rachel, Monaghan, Eimear, Crawford, James, Moug, Susan, Blackwell, James, Boyd-Carson, Hannah, Herrod, Philip, Al-Allaf, Omar, Beattie, Miriam, Bullock, Cameron, Burman, Shivang, Clark, Gemma, Flamey, Nicolas, Flannery, Oliver, Harding, Alexander, Kodiatt, Ben, Lawday, Samuel, Mahapatra, Shivani, Mukundu Nagesh, Navin, Ng, Michael, Rye, Dupinderjit, Yoong, Andrel, Clark, Laura, Deans, Chris, Edirisooriya, Monisha, Carrington, Emma Victoria, Wong, Tsz Lun Ernest, Yusuf, Baasil, Chamberlain, Carla, Duke, Kathryn, Kmiotek, Elizabeth, Botes, Azel, Condie, Natalie, Schrire, Timothy, Shah, Reena, Thomas-Jones, Iolo, Yates, Charlotte, Anthony, Natasha, Matthews, Edward, Sahnan, Kapil, Tankel, James, Tucker, Sally, Winter Beatty, Jasmine, Ziprin, Paul, Duggan, William, Kantartzi, Anastasia, Sridhar, Shruthi, Khaw, Rachel Alys, Srivastava, Prakhar, Underwood, Charlotte, Alves do Canto Brum, Homero, Chopra, Sharat, Davis, Laura, Hughes, Rebecca, Tulley, Joshua, Alberts, Justin, Athisayaraj, Thomas, Olugbemi, Mojolaoluwa, Ahmad, Kasim, Chan, Claudia, Chapman, Gavin, Fleming, Hannah, Fox, Benjamin, Grewar, Julia, Hulse, Kate, Rutherford, Duncan, Sinead, Mackay, Smith, Scott, Speake, Doug, Vaughan-Shaw, Peter G, Christodoulides, Natasha, Kudhail, Simrit, Welch, Matthew, Husaini, Syed Muhibullah, Lambracos, Simon, Anyanwu, Chikamuche, Suresh, Rishi, Thomas, Jimmy Scott, Gleeson, Elizabeth, Platoff, Rebecca, Saif, Areeba, Enumah, Zachary, Etchill, Eric, Gabre-Kidan, Alodia, Bernstein, Mitchell, Carrano, Francesco Maria, Connors, Joseph, Lynn, Patricio, Melis, Marcovalerio, Newman, Elliot, Foster, Deshka S, Perrone, Kenneth, Titan, Ashley, Ahmad, Sarwat, Bafford, Andrea Chao M.D., Dal Molin, Marco, Hanna, Nader, Zafar, Syed Nabeel, Hemmila, Mark, Napolitano, Lena, Wong, Jane J, Chandler, Julia, Wood, Lauren, Wren, Sherry, Ottesen, Taylor, You, Lucia, Yu, Kristin, Arciénega Yañez, María del pilar, Ferreira Fernandes, Martin, González, Daniel, Cubas, Santiago, González, María Catalina, Zubiaurre, Vanessa, Demolin, Rodrigo, Giroff, Nicolas, Sciuto, Pablo, Campos, Maite, Rodríguez Cantera, Gabriela, Deepika, Garg, Simuchimba, Elliot, Bulaya, Anadi, Chibuye, Chali, Chirengendure, Bright, Kabale, Mary-Rose, Kabongo, Kizito, Munthali, James, Mweso, Oliver, Pikiti, Francis, Otieno, James, Lai, Log Tung, Blackman, Brighid, Richards, Sophie, Subramaniam, Suren, Karim, Rafid, Kok, Nathan, Lee, Yanni Dion, Ali, Shabina, Sinha, Aanjaneya, Corrigan, Robert, Barnes, Nicole, Wong, Florence, Dennis, Grace, Jedamzik, Julia, Phillips, Emil, Piette, Wivine, Van hentenryck, Marie, Koco, Houenoukpo, Lawani, Souliath, Kassa, Mamo Woldu, Santos Bezerra, Tainá, Gribnev, Petar, Dimitrov, Dobromir, Krastev, Panche, Oum, Sovannarith, Bonghaseh, Divine Tim, Al Farsi, Maryam, Alsharqawi, Nourah, Acevedo, Veronica, Castillo Barbosa, Andrea Carolina, Giron, Felipe, Leon Rodriguez, Jimmy Paul, Kučan, Darko, Rosko, Damir, Barsic, Neven, Župan, Domagoj, Hegazi, Amgad, Trunčíková, Vendula, Fryba, Vladimir, Mohamed, Mostafa, Sultan, Ahmed, Nagi, Ahmed, Rashad Temerik, Abdallah, Elshawy, Mohamed Elemam, Mahmoud, Moustafa Ibrahim, Omar, Shrouk, Anwar, Mohamed, Rageh, Tarek, Elmokadem, Aya, Gaballa, Khaled, Teppo, Sandra, Turunen, Antti, Pengermä, Pasi, Ballouhey, Quentin, Bergeat, Damien, Weyl, Ariane, Hain, Elisabeth, Gyedu, Adam, Yenli, Edwin, Osei-Poku, Dorcas, Rompou, Vaia-Aliki, Zoikas, Athanasios, Gaitanidis, Apostolos, Koukis, Georgios, Perivoliotis, Konstantinos, Tavlas, Panagiotis, Galanos-Demiris, Konstantinos, Zografos, George, Karavokyros, Ioannis, Xanthopoulou, Georgia, Iordanidou, Eirini, Ayau, Fernanda, Garcia, Allan, Damján, Pekli, Wason, Deepender, B L, Ashika, Rangganata, Ervandy, Kamath, Prerna, O'Connor, Donal B, Pinto, Margherita, Perrone, Fabrizio, Tropeano, Francesca Paola, Troilo, Francesca, Bossi, Daniela, Scala, Dario, Pulitanò, Lucrezia, Carella, Marcella, Pietrabissa, Andrea, Gori, Alice, Giraudo, Giorgio, De Simone, Veronica, Russo, Alfio Alessandro, Braccio, Bartolomeo, Al-Taher, Raed, Athamneh, Sarah, Parker, Andrea, Sawiee, Adnan, Kattia, Amina, Salem, Malik, Tababa, Osama, Shaeeb, Zuhour, Syminas, Vilius, Jurgaitis, Jonas, Damulevičienè, Gytè, Svagzdys, Saulius, Razafimanjato, Narindra Njarasoa Mihaja, Chieng Loo, Ling, Tiong, Ing Ching, Wan Muhmad, Wan Farahiyah, Vijeyan, Harinthiran, Li Ying, Teoh, Grech, Gabriella, Arrangoiz, Rodrigo, Jimenez Ley, Vania Brickelia, Arizpe, Daniel, Lagunes Lara, Elizabeth, Castro López, Elizabeth Victoria, Eaazim, Jose, Gordinou de Gouberville, Marije, Bastiaenen, Vivian, Rottier, Simone, Nahab, Fouad, Ji, Maria Yeonhee, Seyoji, Mohammed, Nwachukwu, Callistus, Emeghara, Okechukwu, Muhammed, Sayyid Egbunu, Idowu, Ayodeji, Sowemimo, Olamiposi, Ogundoyin, Olakayode, Akande, Oluwatosin, Lott, Alexander, Nadeem, Maliha, Laghari, Ahsan Ali, Loya, Asif, Mushtaq, Hassan, Abdullah, Muhammad Tariq, Abuhilal, Baseel, Atawneh, Mohammad, Hamdan, Hamdan, Alhabil, Belal, Srour, Abedelrahman, Mousa, Ibrahim, Da Silva Medina, Luis, Bartosiak, Katarzyna, Ferreira, Pedro, Francisco, Vítor, Lemos, Ricardo, Frutuoso, Luísa, Fernandes, Sara, Fonseca, Telma, Pereira, Jorge, Rachadell, Juan, Torre, Ana, Madeira Martins, Filipe, Carvalho, Ana Cristina, Rodrigues Ferreira, Joana, Ribeiro da Silva, Bruno, Devesa, Helena, Vieira, Ana, Mónica, Inês, Amaro, Margarida, Sousa, Diogo, Reia, Marta, Louro, João, Martins, Ana, Dominguez, Joaquina, Santos, Inês, Freitas Oliveira, Nuno Miguel, Pereira, José Carlos, Silva-Vaz, Pedro, Freire, Ligia, Escrevente, Ricardo, Negoita, Valentina Madalina, Shakhmatov, Dmitry, Nezerwa, Yves, Radulovic, Radosav, Obery, Gareth, Viljoen, Francois, Mendes, Tome, Suarez, Antonio, Moncada, Enrique, Fernandez-Hevia, Maria, Curtis Martínez, Carolina, Gil Garcia, Julia Maria, González Zunzarren, Mariana, Idris, Tarig, Eklöv, Karolina, Grahn, Oskar, Amin, Leila, Blomqvist, Malin, Ajani, Costanza, Kraus, Rebecca, Seeger, Nico, Willemin, Melissa, Rayya, Fadi, Ayash, Mohammad, Msouti, Raneem, Kannas, Israa, Abazid, Eias, Esper, Asil, Slim, Skander, Kavcar, Akil Serdar, Aytac, Erman, Dural, Ahmet Cem, Ilker, Ayse, Eray, Ismail Cem, Kurnaz, Eray, Altiner, Saygin, Tepe, Mustafa Deniz, Şahin, Can, Savli, Evrim, Innocent, Aryon, Babirye, Lilian, Diachenko, Andrii, Hordoskiy, Vladislav, Curry, Heather, Chau, Charlene Yat Che, Robertson, Harry, Mahmoud, Arin, Lennon, Hannah, Loi, Lynette, Kirkham, Emily, McCann, Cameron, Watts, Daniel, Gurung, Binay, Wilson, Michael, Tribedi, Thomas, Garofalo, Eleonora, Zahra, Baryab, MacDonald, Scott, Daniels, Ian, Ng, Nathan, Khosla, Shivun, Olivier, James, Yue, Sum Yu Pansy, Suresh, Gayathri, Wellington, Jack, Lorejo, Emmanuel, Mossaad, Mafdi, Crutcher, Madison, Alimi, Marjan, Baiu, Ioana, Abdou, Hossam, Conway, Alison, Peck, Connor, Perdomo Perez, Mauro Andres, Zulu, Stanley, Nakazwe, Mildred, Burger, Sule, Davies, Justine, Donaldson, Rachel, Ede, Chikwendu, Garden, O James, Lesetedi, Chiapo, Mabedi, Charles, Magill, Laura, Makinde Alakaloko, Felix, Makupe, Alex, Monahan, Mark, Mulira, Soloman, Muller, Elmi, Musowoyo, Jospeh, Olory-Togbe, Jean Léon, Roberts, Tracey, Smith, Martin, Tayler, Viki, Windsor, John, Yepez, Raul, Sundar, Sudha, Runigamugabo, Emmy, Verjee, Azmina, Chen, José, Daya, Leonid, El Aroussi, Nouhaila, Farina, Valeria, Gnintedeme Olivier, Tchianze, Gonzales Nacarino, Mauricio, Hammani, Aamr, Honjo, Sarah, Jacobs, Rebecca, Kimura, Hitomi, Nkoronko, Mugisha, Oscullo Yepez, Jasson Javier, Pin Hung, Wei, Raj, Ankit, Romani Pozo, Alina, Rommaneh, Muna, Sassamela Fabiano, Samuel Chimbioputo, Shiroma Gago, Camila Milagros, Srinivas, Abhishekh, Sung, Chia-Yen, Tai, Aswan, Valle Aranda, Yener Cristyell, Venturini, Sara, and Wilguens Lartigue, Jean

Published
2022
Full Text
View/download PDF

11. Baseline prognostic factors affecting survival in recurrent and/or metastatic salivary gland adenoid cystic carcinoma

Author

Lombardi, Davide, Tomasoni, Michele, Lorini, Luigi, Gurizzan, Cristina, Tomasini, Davide, Ardighieri, Laura, Battocchio, Simonetta, Bozzola, Anna, Mattavelli, Davide, Paderno, Alberto, Zamparini, Manuel, Farina, Davide, Ravanelli, Marco, Maroldi, Roberto, Maddalo, Marta, Magrini, Stefano, Berruti, Alfredo, Deganello, Alberto, Nicolai, Piero, Bossi, Paolo, and Piazza, Cesare

Published
2022
Full Text
View/download PDF

15. Prognostic indicators in clinically node-negative malignant primary salivary tumours of the parotid: A multicentre experience

Author

Fussey, Jonathan, Tomasoni, Michele, Tirelli, Giancarlo, Giordano, Leone, Galli, Andrea, Colangeli, Roberta, Cazzador, Diego, Tofanelli, Margherita, Da Mosto, Maria Cristina, Bianchini, Chiara, Pelucchi, Stefano, Ubayasiri, Kishan, Elsayed, Mahmoud, Long, Patrick, Saratziotis, Athanasios, Hajiioannou, Jiannis, Piazza, Cesare, Deganello, Alberto, Lombardi, Davide, Nicolai, Piero, Pracy, Paul, Sharma, Neil, Nankivell, Paul, Borsetto, Daniele, and Boscolo-Rizzo, Paolo

Published
2021
Full Text
View/download PDF

18. The impact of nodal status in major salivary gland carcinoma: A multicenter experience and proposal of a novel N-classification

Author

Lombardi, Davide, Tomasoni, Michele, Paderno, Alberto, Mattavelli, Davide, Ferrari, Marco, Battocchio, Simonetta, Missale, Francesco, Mazzola, Francesco, Peretti, Giorgio, Mocellin, Davide, Borsetto, Daniele, Fussey, Jonathan M., Nankivell, Paul, Skalidi, Nikoleta, Bussi, Mario, Giordano, Leone, Galli, Andrea, Arrigoni, Gianluigi, Raffetti, Elena, Pracy, Paul, Vander Poorten, Vincent, and Nicolai, Piero

Published
2021
Full Text
View/download PDF

19. Trabectedin may be a valuable treatment option for elderly patients with metastatic soft tissue sarcomas.

Author

Miolo, Gianmaria, Buonadonna, Angela, Lombardi, Davide, Scalone, Simona, Lauretta, Andrea, Della Puppa, Lara, and Corona, Giuseppe

Subjects
FRAIL elderly, OLDER patients, OLDER people, TRABECTEDIN, SARCOMA
Abstract

Background: In the landscape of metastatic soft tissue sarcoma (mSTS) treatment, anthracyclines have shown efficacy; however, their associated toxicity imposes significant limitations, especially in frail elderly patients with mSTS who are highly susceptible to severe adverse effects. In this context, trabectedin, due to its distinct pharmacological profile and safety profile, may represent an interesting alternative being demonstrated to be active in treating mSTS. These features hold particular significance for elderly and unfit patients with mSTS, where balancing treatment benefits with potential adverse effects represents the pivotal objective. Methods: The investigation was focused on a specific group of 11 elderly patients with mSTS aged =70, all undergoing first-line treatment with trabectedin, and it was supported by comprehensive pharmacokinetic and pharmacodynamic studies. Among these patients, 9 out of 11 started the treatment at a dose of 1.5 mg/m2. Results: The primary objective of this investigation is to highlight trabectedin as a valuable first-line treatment option for elderly and unfit patients with mSTS. Additionally, this investigation seeks to explore whether higher administered doses of trabectedin can enhance clinical outcomes while maintaining the same toxicity profiles. The median progression-free survival (PFS) was 77 days (95% CI, 53-89), the median overall survival (OS) was 397 days (95% CI, 66-2,102), while the overall toxicity of grade 3-4 severity amounted to 43%. Conclusion: These findings provide new insights into the clinical outcomes and toxicity associated with trabectedin in an elderly patient population, enhancing our understanding of better treatment approaches for a specific population of patients with mSTS. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

26. The clinicopathological spectrum of olfactory neuroblastoma and sinonasal neuroendocrine neoplasms: Refinements in diagnostic criteria and impact of multimodal treatments on survival

Author

Turri-Zanoni, Mario, Maragliano, Roberta, Battaglia, Paolo, Giovannardi, Marta, Antognoni, Paolo, Lombardi, Davide, Morassi, Maria Laura, Pasquini, Ernesto, Tarchini, Paolo, Asioli, Sofia, Foschini, Maria Pia, Sessa, Fausto, Nicolai, Piero, Castelnuovo, Paolo, and La Rosa, Stefano

Published
2017
Full Text
View/download PDF

27. Mucosal melanoma of the head and neck

Author

Ascierto, Paolo Antonio, Accorona, Remo, Botti, Gerardo, Farina, Davide, Fossati, Piero, Gatta, Gemma, Gogas, Helen, Lombardi, Davide, Maroldi, Roberto, Nicolai, Piero, Ravanelli, Marco, and Vanella, Vito

Published
2017
Full Text
View/download PDF

29. Multi-institutional, International Evaluation of Practice Patterns and Outcomes for Recurrent and Metastatic Sinonasal Undifferentiated Carcinoma.

Author

Saraswathula, Anirudh, Ullah, Mohammed N., Liu, Jacklyn, Takahashi, Yoko, Mahajan, Arushi, Battocchio, Simonetta, Bossi, Paolo, Castelnuovo, Paolo, Facchetti, Fabio, Facco, Carla, Ferrari, Marco, Forster, Martin D., Franchi, Alessandro, Jay, Amrita, Lombardi, Davide, Lund, Valerie J., Mattavelli, Davide, Nicolai, Piero, Rampinelli, Vittorio, and Sessa, Fausto

Subjects
CARCINOMA, METASTASIS, HEALTH facilities, PROGRESSION-free survival, SURVIVAL analysis (Biometry), NASAL cavity, SKULL base
Abstract

This article discusses a study that aimed to evaluate the practice patterns and outcomes for patients with recurrent and metastatic sinonasal undifferentiated carcinoma (SNUC). SNUC is a rare and aggressive tumor of the sinonasal cavity and skull base. The study analyzed data from 97 patients with recurrent or metastatic SNUC and found that the management of these cases varied widely, with different treatment regimens involving surgery, chemotherapy, and/or radiation. The study also found that the survival rates for metastatic and recurrent SNUC were relatively low, highlighting the need for further research to improve outcomes. [Extracted from the article]

Published
2024
Full Text
View/download PDF

34. Prospective, Multicenter Phase II Trial of Non-Pegylated Liposomal Doxorubicin Combined with Ifosfamide in First-Line Treatment of Advanced/Metastatic Soft Tissue Sarcomas.

Author

Buonadonna, Angela, Scalone, Simona, Lombardi, Davide, Fumagalli, Arianna, Guglielmi, Alessandra, Lestuzzi, Chiara, Polesel, Jerry, Canzonieri, Vincenzo, Lamon, Stefano, Giovanis, Petros, Gagno, Sara, Corona, Giuseppe, Mascarin, Maurizio, Belluco, Claudio, De Paoli, Antonino, Fasola, Gianpiero, Puglisi, Fabio, and Miolo, Gianmaria

Subjects
DRUG efficacy, CARDIOTOXICITY, HAND-foot syndrome, DISEASE progression, CLINICAL trials, CONFIDENCE intervals, DOXORUBICIN, IFOSFAMIDE, ANTINEOPLASTIC agents, SARCOMA, PATIENT safety, LONGITUDINAL method, PHARMACODYNAMICS, DISEASE risk factors
Abstract

Simple Summary: This clinical investigation reports the results of a prospective, multicenter phase II trial designed to evaluate the activity and safety of combining non-pegylated liposomal doxorubicin (NPLD) with ifosfamide as a first-line treatment for advanced/metastatic STS. The study results demonstrate a remarkable overall response rate (ORR) alongside a satisfactory disease control rate (DCR) while maintaining acceptable levels of toxicity. The addition of NPLD to ifosfamide, showing high activity and a low toxicity profile, makes this drug combination a useful option for patients with advanced/metastatic STS. These findings provide a promising basis for further comprehensive research into the clinical application of this drug combination in this disease setting. Doxorubicin is a widely used anticancer agent as a first-line treatment for various tumor types, including sarcomas. Its use is hampered by adverse events, among which is the risk of dose dependence. The potential cardiotoxicity, which increases with higher doses, poses a significant challenge to its safe and effective application. To try to overcome these undesired effects, encapsulation of doxorubicin in liposomes has been proposed. Caelyx and Myocet are different formulations of pegylated (PLD) and non-pegylated liposomal doxorubicin (NPLD), respectively. Both PLD and NPLD have shown similar activity compared with free drugs but with reduced cardiotoxicity. While the hand–foot syndrome exhibits a high occurrence among patients treated with PLD, its frequency is notably reduced in those receiving NPLD. In this prospective, multicenter, one-stage, single-arm phase II trial, we assessed the combination of NPLD and ifosfamide as first-line treatment for advanced/metastatic soft tissue sarcoma (STS). Patients received six cycles of NPLD (50 mg/m2) on day 1 along with ifosfamide (3000 mg/m2 on days 1, 2, and 3 with equidose MESNA) administered every 3 weeks. The overall response rate, yielding 40% (95% CI: 0.29–0.51), resulted in statistical significance; the disease control rate stood at 81% (95% CI: 0.73—0.90), while only 16% (95% CI: 0.08–0.24) of patients experienced a progressive disease. These findings indicate that the combination of NPLD and ifosfamide yields a statistically significant response rate in advanced/metastatic STS with limited toxicity. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

35. Current management and future challenges in salivary glands cancer.

Author

Locati, Laura D., Ferrarotto, Renata, Licitra, Lisa, Benazzo, Marco, Preda, Lorenzo, Farina, Davide, Gatta, Gemma, Lombardi, Davide, Nicolai, Piero, Vander Poorten, Vincent, Lee Kiang Chua, Melvin, Vischioni, Barbara, Sanguineti, Giuseppe, Morbini, Patrizia, Fonseca, Isabel, Sozz, Davide, Merlotti, Anna, and Orlandi, Ester

Subjects
SALIVARY gland cancer, MAGNETIC resonance
Abstract

Salivary gland cancers (SGCs) are rare, accounting for less than 5% of all malignancies of the head and neck region, and are morphologically heterogeneous. The diagnosis is mainly based on histology, with the complementary aid of molecular profiling, which is helpful in recognizing some poorly differentiated, borderline, or atypical lesions. Instrumental imaging defines the diagnosis, representing a remarkable tool in the treatment plan. Ultrasound and magnetic resonance are the most common procedures used to describe the primary tumour. The treatment of SGCs is multimodal and consists of surgery, radiotherapy, and systemic therapy; each treatment plan is, however, featured on the patient and disease's characteristics. On 24 June 2022, in the meeting "Current management and future challenges in salivary gland cancers" many experts in this field discussed the state of the art of SGCs research, the future challenges and developments. After the meeting, the same pool of experts maintained close contact to keep these data further updated in the conference proceedings presented here. This review collects the insights and suggestions that emerged from the discussion during and after the meeting per se. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

36. Metabolic Clues to Bile Acid Patterns and Prolonged Survival in Patients with Metastatic Soft-Tissue Sarcoma Treated with Trabectedin.

Author

Miolo, Gianmaria, Buonadonna, Angela, Scalone, Simona, Lombardi, Davide, Della Puppa, Lara, Steffan, Agostino, and Corona, Giuseppe

Subjects
BILE acids, TRABECTEDIN, OVERALL survival, PROGNOSIS, SARCOMA, FARNESOID X receptor, METABOLOMICS
Abstract

Metastatic soft-tissue sarcomas (mSTS) encompass a highly heterogeneous group of rare tumours characterized by different clinical behaviours and outcomes. Currently, prognostic factors for mSTS are very limited, posing significant challenges in predicting patient survival. Within a cohort of 39 mSTS patients undergoing trabectedin treatment, it was remarkable to find one patient who underwent 73 cycles of trabectedin achieving an unforeseen clinical outcome. To identify contributing factors to her exceptional long-term survival, we have explored circulation metabolomics and biohumoral biomarkers to uncover a potential distinct host biochemical phenotype. The long-term survival patient compared with the other mSTS patients exhibited a distinctive metabolic profile characterized by remarkably higher levels of ursodeoxycholic acid (UDCA) derivatives and vitamin D and lower levels of lithocholic acid (LCA) derivatives, as well as reduced levels of inflammatory C-Reactive Protein 4 (C-RP4) biomarker. Despite its exploratory nature, this study reveals a potential association between specific bile acid metabolic profiles and mSTS patients' prognosis. Enhanced clinical understanding of the interplay between bile acid metabolism and disease progression could pave the way for new targeted therapeutic interventions which may improve the overall survival of mSTS patients. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

39. Pharmacometabolomics of trabectedin in metastatic soft tissue sarcoma patients.

Author

Corona, Giuseppe, Di Gregorio, Emanuela, Buonadonna, Angela, Lombardi, Davide, Scalone, Simona, Steffan, Agostino, and Miolo, Gianmaria

Subjects
TRABECTEDIN, SARCOMA, AMINO acid derivatives, LATENT structure analysis, CITRULLINE, PARTIAL least squares regression, BILE acids, ANTINEOPLASTIC agents
Abstract

Objective: Trabectedin is an anti-cancer drug commonly used for the treatment of patients with metastatic soft tissue sarcoma (mSTS). Despite its recognized efficacy, significant variability in pharmacological response has been observed among mSTS patients. To address this issue, this pharmacometabolomics study aimed to identify pre-dose plasma metabolomics signatures that can explain individual variations in trabectedin pharmacokinetics and overall clinical response to treatment. Methods: In this study, 40 mSTS patients treated with trabectedin administered by 24 h-intravenous infusion at a dose of 1.5 mg/m2 were enrolled. The patients' baseline plasma metabolomics profiles, which included derivatives of amino acids and bile acids, were analyzed using multiple reaction monitoring LC-MS/MS together with their pharmacokinetics profile of trabectedin. Multivariate Partial least squares regression and univariate statistical analyses were utilized to identify correlations between baseline metabolite concentrations and trabectedin pharmacokinetics, while Partial Least Squares-Discriminant Analysis was employed to evaluate associations with clinical response. Results: The multiple regression model, derived from the correlation between the AUC of trabectedin and pre-dose metabolomics, exhibited the best performance by incorporating cystathionine, hemoglobin, taurocholic acid, citrulline, and the phenylalanine/tyrosine ratio. This model demonstrated a bias of 4.6% and a precision of 17.4% in predicting drug AUC, effectively accounting for up to 70% of the inter-individual pharmacokinetic variability. Through the use of Partial least squares-Discriminant Analysis, cystathionine and hemoglobin were identified as specific metabolic signatures that effectively distinguish patients with stable disease from those with progressive disease. Conclusions: The findings from this study provide compelling evidence to support the utilization of pre-dose metabolomics in uncovering the underlying causes of pharmacokinetic variability of trabectedin, as well as facilitating the identification of patients who are most likely to benefit from this treatment. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

40. International Multicenter Study of Clinical Outcomes of Sinonasal Melanoma Shows Survival Benefit for Patients Treated with Immune Checkpoint Inhibitors and Potential Improvements to the Current TNM Staging System.

Author

Lechner, Matt, Takahashi, Yoko, Turri-Zanoni, Mario, Ferrari, Marco, Liu, Jacklyn, Counsell, Nicholas, Mattavelli, Davide, Rampinelli, Vittorio, Vermi, William, Lombardi, Davide, Saade, Rami, Park, Ki Wan, Schartinger, Volker H., Franchi, Alessandro, Facco, Carla, Sessa, Fausto, Battocchio, Simonetta, Fenton, Tim R., Vaz, Francis M., and O'Flynn, Paul

Subjects
IMMUNE checkpoint inhibitors, OVERALL survival, TREATMENT effectiveness, PARANASAL sinuses, IMMUNE checkpoint proteins, DEEP brain stimulation
Abstract

Objectives Sinonasal mucosal melanoma (SNMM) is an extremely rare and challenging sinonasal malignancy with a poor prognosis. Standard treatment involves complete surgical resection, but the role of adjuvant therapy remains unclear. Crucially, our understanding of its clinical presentation, course, and optimal treatment remains limited, and few advancements in improving its management have been made in the recent past. Methods We conducted an international multicenter retrospective analysis of 505 SNMM cases from 11 institutions across the United States, United Kingdom, Ireland, and continental Europe. Data on clinical presentation, diagnosis, treatment, and clinical outcomes were assessed. Results One-, three-, and five-year recurrence-free and overall survival were 61.4, 30.6, and 22.0%, and 77.6, 49.2, and 38.3%, respectively. Compared with disease confined to the nasal cavity, sinus involvement confers significantly worse survival; based on this, further stratifying the T3 stage was highly prognostic (p < 0.001) with implications for a potential modification to the current TNM staging system. There was a statistically significant survival benefit for patients who received adjuvant radiotherapy, compared with those who underwent surgery alone (hazard ratio [HR] = 0.74, 95% confidence interval [CI]: 0.57–0.96, p = 0.021). Immune checkpoint blockade for the management of recurrent or persistent disease, with or without distant metastasis, conferred longer survival (HR = 0.50, 95% CI: 0.25–1.00, p = 0.036). Conclusions We present findings from the largest cohort of SNMM reported to date. We demonstrate the potential utility of further stratifying the T3 stage by sinus involvement and present promising data on the benefit of immune checkpoint inhibitors for recurrent, persistent, or metastatic disease with implications for future clinical trials in this field. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

43. Corrigendum to “Prognostic indicators in clinically node-negative malignant primary salivary tumours of the parotid: A multicentre experience”. [Oral Oncol. 123 (2021) 105577]

Author

Fussey, Jonathan, Tomasoni, Michele, Tirelli, Giancarlo, Giordano, Leone, Galli, Andrea, Colangeli, Roberta, Cazzador, Diego, Tofanelli, Margherita, da Mosto, Maria Cristina, Bianchini, Chiara, Pelucchi, Stefano, Ubayasiri, Kishan, Elsayed, Mahmoud, Long, Patrick, Saratziotis, Athanasios, Hajiioannou, Jiannis, Golusiński, Paweł, Szewczyk, Mateusz, Piazza, Cesare, Deganello, Alberto, Lombardi, Davide, Nicolai, Piero, Pracy, Paul, Sharma, Neil, Nankivell, Paul, Borsetto, Daniele, and Boscolo-Rizzo, Paolo

Published
2022
Full Text
View/download PDF

44. Intraoperative neuromonitoring in thyroid surgery: a point prevalence survey on utilization, management, and documentation in Italy

Author

Dionigi, Gianlorenzo, Lombardi, Davide, Lombardi, Celestino Pio, Carcoforo, Paolo, Boniardi, Marco, Innaro, Nadia, Chiofalo, Maria Grazia, Cavicchi, Ottavio, Biondi, Antonio, Basile, Francesco, Zaccaroni, Angelo, Mangano, Alberto, Leotta, Andrea, Lavazza, Matteo, Calò, Pietro Giorgio, Nicolosi, Angelo, Castelnuovo, Paolo, Nicolai, Piero, Pezzullo, Luciano, De Toma, Giorgio, Bellantone, Rocco, Sacco, Rosario, and a Working Group for Neural Monitoring in Thyroid and Parathyroid Surgery in Italy

Published
2014
Full Text
View/download PDF

49. Temporal Evolution and Prognostic Role of Indeterminate Response Sub-Groups in Patients with Differentiated Thyroid Cancer after Initial Therapy with Radioiodine.

Author

Albano, Domenico, Bellini, Pietro, Dondi, Francesco, Calabrò, Anna, Casella, Claudio, Taboni, Stefano, Lombardi, Davide, Treglia, Giorgio, and Bertagna, Francesco

Subjects
THERAPEUTIC use of iodine isotopes, TEMPORAL lobe, THYROID gland tumors, RETROSPECTIVE studies, DESCRIPTIVE statistics, PROGRESSION-free survival
Abstract

Simple Summary: The main aim of this retrospective study was to investigate the dynamic evolution and prognostic role of patients affected by DTC and IR after initial therapy. From January 2010 to December 2017, 2176 patients who received radioiodine (RAI) for DTC after total or near total thyroidectomy were included. Among them, 288 had IR one year after therapy (187 TgAb+, 76 Tg+, 25 imaging+). IRTg+ patients had a higher probability of evolving into an incomplete response. Only stimulated Tg after one year and nodal disease at diagnosis may predict the final status of the disease. Progression-free survival was significantly shorter in IRTg+ than IRTgAb+ and IRimaging+ groups and in patients with sTg > 3.3 ng/mL. The clinical outcome of patients affected by Differentiated Thyroid Carcinoma (DTC) and an indeterminate response (IR) after initial therapy is not yet clear. IR includes three different sub-groups of patients: (1) IRTg+ group: Detectable thyroglobulin (Tg), regardless of antithyroglobulin antibodies (TgAb) presence or imaging studies; (2) IRTgAb+ group: Positive TgAb, regardless of Tg levels and nonspecific imaging findings; (3) IRImaging+ group: Nonspecific findings on neck ultrasonography or faint uptake in the thyroid bed on the whole-body scan, negative TgAb, and undetectable Tg. The main aim of this retrospective study was to investigate the dynamic evolution and prognostic role of these patients. From January 2010 to December 2017, 2176 patients who received radioiodine for DTC after total thyroidectomy were included. Two-hundred-eighty-eight patients had IR one year after therapy (187 TgAb+, 76 Tg+, 25 imaging+). After two years, 110 patients (38%) were reclassified as an excellent response and 5 (2%) as an incomplete response; after five years, 221 (77%) achieved an excellent response and 11 (4%) showed an incomplete response. One-year stimulated Tg and nodal disease at diagnosis may predict the final status of the disease. Progression-free survival was significantly shorter in IRTg+ than in IRTgAb+ and IRimaging+ groups. Considering Tg+ patients, a threshold of 3.3 ng/mL is best to predict prognosis. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results