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This study addressed the characteristics of lateral pile-soil interactions in coral sand foundation using a series of direct shear, triaxial, and model pile tests. Through the comprehensive analysis of the stress state of the coral sand around pile, it was found that the soil resistance is mainly dominated by frontal squeezing resistance. Accordingly, the framework of the modified p-y model was determined, namely the function type, exponents of depth term, and the mark of entering the plastic state. The modified p-y model adopts a normalized dimensionless form, and it is composed of the first nonlinear segment represented by the power function and the plastic state at large displacements represented by a straight line. The final p-y model was calibrated using the results of the model pile test. Subsequently, the validity of the modified p-y model was verified by the experimental results of this study and other researchers. The soil reactions and pile responses predicted by the modified p-y model were in a reasonable agreement with the measured data. Finally, the modified p-y model was compared with the existing p-y models, thus confirming its rationality and applicability. Key words: coral sand, p-y curve, direct shear test, triaxial test, model pile test, Introduction Pile foundations are commonly used to resist the lateral loads applied to structures (Luan et al. 2020a, 2020b). To date, several approaches are available to determine the behavior of [...]

Objective: This study aimed to investigate the quality differences among different hybrid enoki mushrooms （Flammulina filiformis） strains and breed new strains with high quality. Methods: Two different protoplast monocytes of yellow enoki mushrooms Fv1923 were used as one of the parents to cross with 6 enoki mushrooms protoplasts （2 yellow and 4 white strains）, and a total of 12 yellow hybrid strains were obtained. Principal component analysis and cluster analysis were used to evaluate the free amino acids of 12 hybrid strains, and the flavor diversity of different protoplast hybrid strains was also evaluated. Results: The average contents of essential amino acids, non-essential amino acids and total amino acids were 7.71, 22.83 and 30.54 mg/g, respectively. Methionine was the first limiting amino acid of strains F1, F11, F15, F16, F21, F29, F39, F41 and F42. The amino acid components in 12 hybrid strains had a strong correlation, and the cumulative variance contribution rate of the four principal components was 87.15%, which better reflected the comprehensive information of amino acids in hybrid strains. The top two strains in comprehensive scores were hybrid strains of Shangyan 1820 and Fv1923. Cluster analysis showed that 12 strains were divided into 6 groups, which was consistent with the results of principal component analysis and reflected the variety differences of free amino acids in different strains. Conclusion: There were significant differences in the composition and content of free amino acids inhybrid strains with different protoplast monocytes as parents.

Polymer hydrogels find extensive application in biomedicine, serving specific purposes such as drug delivery, biosensing, bioimaging, cancer therapy, tissue engineering, and others. In response to the growing threat of bacterial infections and the escalating resistance to conventional antibiotics, this research introduces a novel injectable, self‐healing antimicrobial hydrogel comprising bioactive aldolized hyaluronic acid (AHA) and quaternized chitosan (QCS). This designed QCS/AHA hydrogel incorporates self‐assembling peptide nanofibers (PNFs) and small‐sized silver nanoparticles (AgNPs) for tailored functionality. The resulting hybrid QCS/AHA/PNF/AgNPs hydrogel demonstrates impressive rheological characteristics, broad‐spectrum antimicrobial efficacy, and high biocompatibility. Notably, its antimicrobial effectiveness against Escherichia coli and S. aureus surpasses 99.9%, underscoring its potential for treating infectious wounds. Moreover, the rheological analysis confirms its excellent shear‐thinning and self‐healing properties, enabling it to conform closely to irregular wound surfaces. Furthermore, the cytotoxicity assessment reveals its compatibility with human umbilical vein endothelial cells, exhibiting no significant adverse effects. The combined attributes of this bioactive QCS/AHA/PNF/AgNPs hydrogel position it as a promising candidate for antimicrobial applications and wound healing. [ABSTRACT FROM AUTHOR]

Since Chinese universities launched the postgraduate program of the Master of Translation and Interpreting (MTI) in 2007, approximately 300 high education institutions in China have been authorized to offer the MTI program. Behind the drastic springing-up of MTI programs during the decade, MTI teachers' professional development draws the attention of MTI administrators and researchers. This study adopted a mixed-method of a large-scale survey among 514 MTI teachers across China and a qualitative interview study of seven participants and discussed MTI teachers' perceptions of dilemmas and inner-world needs in their professional development. The findings indicate that MTI teachers' dilemmas arise from the contradiction and entanglement in three mutually repulsive sectors of their professional development, i.e., teaching, research, and translation/interpreting practice, which hinder their professional development. And on the basis of the analysis, the present study proposes a synchronized "three-in-one" mechanism model with encouraging policies and environments as lubricant for the sustainable development of MTI teachers in the future, and it is hoped that this empirical research would provide some practice implications for the professional development of translation and interpreting teachers in China and beyond. [ABSTRACT FROM AUTHOR]