Search

Your search keyword '"Li, Weiqin"' showing total 770 results
Start Over Author "Li, Weiqin" Publication Type Academic Journals
770 results on '"Li, Weiqin"'

11. Correlation between protoporphyrin Ⅸ and hepatitis, cirrhosis, and liver cancer

Author

WANG Xia, CUI Jie, LIU Mi, LI Weiqin, and LIU Kaige

Subjects
chronic hepatitis b, liver cirrhosis, liver cancer, protoporphyrin ⅸ, cholestasis, liver function damage, Medicine
Abstract

Objective To investigate the clinical significance of protoporphyrin Ⅸ (PPⅨ) in different stages of liver disease development, including hepatitis, cirrhosis, and liver cancer. Methods A total of 41 patients with chronic hepatitis (hepatitis group), 33 patients with liver cirrhosis (cirrhosis group), and 19 patients with liver cancer (liver cancer group) who visited the First Affiliated Hospital of Xi'an Medical University from January 2022 to December 2022 were selected as study object. Additionally, 40 healthy examinees during the same period were selected as the health control group. The basic information, blood routine, liver function, coagulation function, alpha fetoprotein (AFP)，controlled attenuation parameter (CAP)，liver stiffness measurement (LSM)，γ-glutamyl transpeptidase to platelet ratio (GPR) from each group were collected and compared. The correlation between various indicators and PPⅨ was analyzed. And the predictive value of PPⅨ and liver function related indicators on liver stiffness was analyzed. Results There were significant differences in gender, age, and PPⅨ between the hepatitis group, liver cirrhosis group, and liver cancer group compared to the control group (P

Published
2023
Full Text
View/download PDF

27. Association between pretreatment lymphocyte count and efficacy of immune-enhancing therapy in acute necrotising pancreatitis: a post-hoc analysis of the multicentre, randomised, placebo-controlled TRACE trial

Author

Ke, Lu, Mao, Wenjian, Zhou, Jing, Xu, Minyi, Jiang, Wendi, Zhang, He, Lin, Jiajia, Lu, Mengjie, Chen, Yan, Ma, Mingmin, Li, Gang, Ye, Bo, Li, Baiqiang, Tong, Zhihui, Liu, Yuxiu, Li, Weiqin, Shao, Fang, Chen, Tao, Lv, Nonghua, Zhu, Yin, Xia, Liang, He, Wenhua, Zhenping, Chen, Pan, Xinting, Zhu, Qingyun, Wan, Youdong, Mei, Hong, Li, Kang, Chen, Miao, He, Chengjian, Yao, Hongyi, Zhu, Zigui, Gu, Weili, Lu, Weihua, Wu, Jingyi, Zhou, Feng, Tu, Shumin, Fu, Long, Xue, Bingg, Ni, Haibin, Huang, Xiaofei, Zhou, Dandan, Zhang, Guoxiu, Ren, Lening, Li, Dahuan, Zhao, Xiangyang, Zhao, Wei, Chen, Xiaomei, Sun, Junli, Xin, Keke, Chen, Weiwei, Xu, Qingcheng, Song, Jingchun, Zeng, Qingbo, Shao, Min, Zhao, Dongsheng, Tu, Jianfeng, Yang, Honggup, Windsor, John, and Ma, Penglin

Published
2023
Full Text
View/download PDF

28. Circulating Lysophosphatidylcholines in Early Pregnancy and Risk of Gestational Diabetes in Chinese Women.

Author

Liu, Jinnan, Li, Jing, Li, Sainan, Leng, Junhong, Li, Weiqin, Yang, Wen, Huo, Xiaoxu, Chen, Liwei, Ma, Ronald CW, Hu, Gang, Fang, Zhongze, and Yang, Xilin

Subjects
Humans, Diabetes, Gestational, Lysophosphatidylcholines, Glucose Tolerance Test, Prognosis, Risk Factors, Case-Control Studies, Follow-Up Studies, Prospective Studies, Gestational Age, Pregnancy, Adult, China, Female, Chinese women, bile acids, gestational diabetes mellitus, metabolism, lysophosphatidylcholines, Clinical Sciences, Paediatrics and Reproductive Medicine, Endocrinology & Metabolism
Abstract

ObjectivesThis study aimed to explore associations of lysophosphatidylcholines (LPCs) in early pregnancy with gestational diabetes mellitus (GDM), and whether LPCs mediated the associations of bile acids with GDM risk or had interactive effects with bile acids on GDM risk.DesignWe conducted a 1:1 nested case-control study (n = 486) from a large prospective pregnant women cohort in urban Tianjin, China. Blood samples were collected at their first antenatal care visit (median at 10th gestational week). LPCs were measured by liquid chromatography-tandem mass spectrometry analysis. Conditional binary logistic regression and restricted cubic spline analysis were used to identify cutoff points of these metabolites for GDM risk.ResultsOf the 6 detectable LPCs, LPC14:0 less than 0.24 nmol/mL, LPC15:0 at 0.45 nmol/mL or greater, and LPC18:0 at 18.00 nmol/mL or greater were independently associated with GDM risk. Adjustment for LPC18:0 slightly attenuated odds ratios (ORs) of deoxycholic acid (DCA, ≤ 0.36 nmol/mL) and glycoursodeoxycholic acid (GUDCA, ≤ 0.07 nmol/mL) for GDM, and the correlations of DCA and GUDCA with LPC18:0 were weak. However, the presence of DCA at 0.36 nmol/mL or less greatly amplified the adjusted OR of LPC18:0 at 18.00 nmol/mL or greater alone for GDM from 8.18 (2.51-26.7) up to 17.7 (6.64-47.1), with significant additive interaction. Similarly, the presence of GUDCA at 0.07 nmol/mL or less also greatly amplified the adjusted OR of LPC18:0 at 18.00 nmol/mL or greater alone for GDM from 17.2 (1.77-168) up to 73.8 (12.7-429), with significant additive interaction.ConclusionsLPCs in early pregnancy were associated with GDM risk. Low DCA or GUDCA greatly amplified the effect of high LPC18:0 on GDM, and its molecular mechanism is worth further investigations.

Published
2020

30. Immune enhancement in patients with predicted severe acute necrotising pancreatitis: a multicentre double-blind randomised controlled trial

Author

Ke, Lu, Zhou, Jing, Mao, Wenjian, Chen, Tao, Zhu, Yin, Pan, Xinting, Mei, Hong, Singh, Vikesh, Buxbaum, James, Doig, Gordon, He, Chengjian, Gu, Weili, Lu, Weihua, Tu, Shumin, Ni, Haibin, Zhang, Guoxiu, Zhao, Xiangyang, Sun, Junli, Chen, Weiwei, Song, Jingchun, Shao, Min, Tu, Jianfeng, Xia, Liang, He, Wenhua, Zhu, Qingyun, Li, Kang, Yao, Hongyi, Wu, Jingyi, Fu, Long, Jiang, Wendi, Zhang, He, Lin, Jiajia, Li, Baiqiang, Tong, Zhihui, Windsor, John, Liu, Yuxiu, and Li, Weiqin

Published
2022
Full Text
View/download PDF

40. Correction to: Actively implementing an evidence-based feeding guideline for critically ill patients (NEED): a multicenter, cluster-randomized, controlled trial

Author

Ke, Lu, Lin, Jiajia, Doig, Gordon S., van Zanten, Arthur R. H., Wang, Yang, Xing, Juan, Zhang, Zhongheng, Chen, Tao, Zhou, Lixin, Jiang, Dongpo, Shi, Qindong, Lin, Jiandong, Liu, Jun, Cheng, Aibin, Liang, Yafeng, Gao, Peiyang, Sun, Junli, Liu, Wenming, Yang, Zhenyu, Zhang, Rumin, Xing, Wei, Zhang, An, Zhou, Zhigang, Zhou, Tingfa, Liu, Yang, Tong, Fei, Wang, Qiuhui, Pan, Aijun, Huang, Xiaobo, Fan, Chuming, Lu, Weihua, Shi, Dongwu, Wang, Lei, Li, Wei, Gu, Liming, Xie, Yingguang, Sun, Rongqing, Guo, Feng, Han, Lin, Zhou, Lihua, Zheng, Xiangde, Shan, Feng, Liu, Jianbo, Ai, Yuhang, Qu, Yan, Li, Liandi, Li, Hailing, Pan, Zhiguo, Xu, Donglin, Zou, Zhiqiang, Gao, Yan, Yang, Chunli, Kou, Qiuye, Zhang, Xijing, Wu, Jinglan, Qian, Chuanyun, Zhang, Weixing, Zhang, Minjie, Zong, Yuan, Qin, Bingyu, Zhang, Fusen, Zhai, Zhe, Sun, Yun, Chang, Ping, Yu, Bo, Yu, Min, Yuan, Shiying, Deng, Yijun, Zhao, Liyun, Zang, Bin, Li, Yuanfei, Zhou, Fachun, Chen, Xiaomei, Shao, Min, Wu, Weidong, Wu, Ming, Zhang, Zhaohui, Li, Yimin, Guo, Qiang, Wang, Zhiyong, Gong, Yuanqi, Song, Yunlin, Qian, Kejian, Feng, Yongjian, Fu, Baocai, Liu, Xueyan, Li, Zhiping, Gong, Chuanyong, Sun, Cheng, Yu, Jian, Tang, Zhongzhi, Huang, Linxi, Ma, Biao, He, Zhijie, Zhou, Qingshan, Yu, Rongguo, Tong, Zhihui, and Li, Weiqin

Published
2022
Full Text
View/download PDF

41. Actively implementing an evidence-based feeding guideline for critically ill patients (NEED): a multicenter, cluster-randomized, controlled trial

Author

Ke, Lu, Lin, Jiajia, Doig, Gordon S., van Zanten, Arthur R. H., Wang, Yang, Xing, Juan, Zhang, Zhongheng, Chen, Tao, Zhou, Lixin, Jiang, Dongpo, Shi, Qindong, Lin, Jiandong, Liu, Jun, Cheng, Aibin, Liang, Yafeng, Gao, Peiyang, Sun, Junli, Liu, Wenming, Yang, Zhenyu, Zhang, Rumin, Xing, Wei, Zhang, An, Zhou, Zhigang, Zhou, Tingfa, Liu, Yang, Tong, Fei, Wang, Qiuhui, Pan, Aijun, Huang, Xiaobo, Fan, Chuming, Lu, Weihua, Shi, Dongwu, Wang, Lei, Li, Wei, Gu, Liming, Xie, Yingguang, Sun, Rongqing, Guo, Feng, Han, Lin, Zhou, Lihua, Zheng, Xiangde, Shan, Feng, Liu, Jianbo, Ai, Yuhang, Qu, Yan, Li, Liandi, Li, Hailing, Pan, Zhiguo, Xu, Donglin, Zou, Zhiqiang, Gao, Yan, Yang, Chunli, Kou, Qiuye, Zhang, Xijing, Wu, Jinglan, Qian, Chuanyun, Zhang, Weixing, Zhang, Minjie, Zong, Yuan, Qin, Bingyu, Zhang, Fusen, Zhai, Zhe, Sun, Yun, Chang, Ping, Yu, Bo, Yu, Min, Yuan, Shiying, Deng, Yijun, Zhao, Liyun, Zang, Bin, Li, Yuanfei, Zhou, Fachun, Chen, Xiaomei, Shao, Min, Wu, Weidong, Wu, Ming, Zhang, Zhaohui, Li, Yimin, Guo, Qiang, Wang, Zhiyong, Gong, Yuanqi, Song, Yunlin, Qian, Kejian, Feng, Yongjian, Fu, Baocai, Liu, Xueyan, Li, Zhiping, Gong, Chuanyong, Sun, Cheng, Yu, Jian, Tang, Zhongzhi, Huang, Linxi, Ma, Biao, He, Zhijie, Zhou, Qingshan, Yu, Rongguo, Tong, Zhihui, and Li, Weiqin

Published
2022
Full Text
View/download PDF

50. Effects of intensive treatment of Chinese women with gestational diabetes on the risk of offspring being overweight from 3 to 8 years of age.

Author

Li, Jing, Zhang, Rui, Zhang, Cuiping, Liu, Gongshu, Li, Weiqin, Wang, Hui, Qiao, Yijuan, Yu, Zhijie, Hu, Gang, Chan, Juliana C. N., Leng, Junhong, and Yang, Xilin

Subjects
HIGH-risk pregnancy, OVERWEIGHT children, GESTATIONAL diabetes, MATERNAL age, DIASTOLIC blood pressure, MEDICAL personnel, CHI-squared test
Abstract

A study published in the journal Diabetes, Obesity & Metabolism found that children born to mothers with gestational diabetes have an increased risk of being overweight as they grow up. The study also found that intensive treatment of gestational diabetes during pregnancy improved outcomes for both mother and baby, but did not reduce the risk of childhood obesity. The researchers suggest that prevention and intensive management of gestational diabetes are important in reducing the risk of childhood obesity. They also recommend that children from gestational diabetes pregnancies adopt a healthy lifestyle from an early age to reduce the risk of future health problems. Further research is needed to better understand these relationships and develop effective health management strategies for women with gestational diabetes and their children. [Extracted from the article]

Published
2024
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results