Background: Patients who undergo carpal tunnel surgery sometimes complain of the restriction of the grip and pinch function, palmar tenderness, cosmetic problems, and scar formation at the site of the incision.Aims: We used a modified mini uni-skin incision with appropriate hand position for microscopic view in the surgical treatment of carpal tunnel syndrome to prevent cosmetic problems related with scar formation after surgery.Settings and Design: In this study we used two different skin incision techniques; mini uni-skin incision and standard incision. In mini uni-skin incision technique the hands were positioned in a way that the wrist are hyperextended. A small skin incision one cm long was done from the inferior flexion crease towards the point between the thirth and fourth fingers.Materials and Methods: Standard incision and mini uni-skin incision were compared according to their cosmetic result, grip and pinch function, palmar tenderness, and painful scar formation.Statistical Analysis: Student -t test was used for this study.Results: 56 (43%) patients were operated with mini uni-skin incision, and 73 (57%) cases were operated with standard incision. The scores of grip, pinch and cosmetic results were better in the patients who were operated with mini uni-skin incision technique from those of standard incision.Conclusion: In this clinical study we used a modified skin incision (mini uni-skin incision) technique in the surgical treatment of carpal tunnel surgery. Our results revealed that mini uni-skin incision is superior from the standard incision. [ABSTRACT FROM AUTHOR]