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Start Over Author "Kemp, B" Publication Type Academic Journals
1,640 results on '"Kemp, B"'

6. Achieving accurate estimates of fetal gestational age and personalised predictions of fetal growth based on data from an international prospective cohort study: a population-based machine learning study

Author

Norris, S, Abbott, SE, Abubakar, A, Acedo, J, Ahmed, I, Al-Aamri, F, Al-Abduwani, J, Al-Abri, J, Alam, D, Albernaz, E, Algren, H, Al-Habsi, F, Alija, M, Al-Jabri, H, Al-Lawatiya, H, Al-Rashidiya, B, Altman, DG, Al-Zadjali, WK, Andersen, HF, Aranzeta, L, Ash, S, Baricco, M, Barros, FC, Barsosio, H, Batiuk, C, Batra, M, Berkley, J, Bertino, E, Bhan, MK, Bhat, BA, Bhutta, ZA, Blakey, I, Bornemeier, S, Bradman, A, Buckle, M, Burnham, O, Burton, F, Capp, A, Cararra, VI, Carew, R, Carrara, VI, Carter, AA, Carvalho, M, Chamberlain, P, Cheikh, Ismail L, Cheikh Ismail, L, Choudhary, A, Choudhary, S, Chumlea, WC, Condon, C, Corra, LA, Cosgrove, C, Craik, R, da Silveira, MF, Danelon, D, de Wet, T, de Leon, E, Deshmukh, S, Deutsch, G, Dhami, J, Di, Nicola P, Dighe, M, Dolk, H, Domingues, M, Dongaonkar, D, Enquobahrie, D, Eskenazi, B, Farhi, F, Fernandes, M, Finkton, D, Fonseca, S, Frederick, IO, Frigerio, M, Gaglioti, P, Garza, C, Gilli, G, Gilli, P, Giolito, M, Giuliani, F, Golding, J, Gravett, MG, Gu, SH, Guman, Y, He, YP, Hoch, L, Hussein, S, Ibanez, D, Ioannou, C, Jacinta, N, Jackson, N, Jaffer, YA, Jaiswal, S, Jimenez-Bustos, JM, Juangco, FR, Juodvirsiene, L, Katz, M, Kemp, B, Kennedy, S, Ketkar, M, Khedikar, V, Kihara, M, Kilonzo, J, Kisiang'ani, C, Kizidio, J, Knight, CL, Knight, HE, Kunnawar, N, Laister, A, Lambert, A, Langer, A, Lephoto, T, Leston, A, Lewis, T, Liu, H, Lloyd, S, Lumbiganon, P, Macauley, S, Maggiora, E, Mahorkar, C, Mainwaring, M, Malgas, L, Matijasevich, A, McCormick, K, McGready, R, Miller, R, Min, A, Mitidieri, A, Mkrtychyan, V, Monyepote, B, Mota, D, Mulik, I, Munim, S, Muninzwa, D, Musee, N, Mwakio, S, Mwangudzah, H, Napolitano, R, Newton, CR, Ngami, V, Noble, JA, Norris, T, Nosten, F, Oas, K, Oberto, M, Occhi, L, Ochieng, R, Ohuma, EO, Olearo, E, Olivera, I, Owende, MG, Pace, C, Pan, Y, Pang, RY, Papageorghiou, AT, Patel, B, Paul, V, Paulsene, W, Puglia, F, Purwar, M, Rajan, V, Raza, A, Reade, D, Rivera, J, Rocco, DA, Roseman, F, Roseman, S, Rossi, C, Rothwell, PM, Rovelli, I, Saboo, K, Salam, R, Salim, M, Salomon, L, Sanchez, Luna M, Sande, J, Sarris, I, Savini, S, Sclowitz, IK, Seale, A, Shah, J, Sharps, M, Shembekar, C, Shen, YJ, Shorten, M, Signorile, F, Singh, A, Sohoni, S, Somani, A, Sorensen, TK, Soria- Frisch, A, Staines Urias, E, Stein, A, Stones, W, Taori, V, Tayade, K, Todros, T, Uauy, R, Varalda, A, Venkataraman, M, Victora, C, Villar, J, Vinayak, S, Waller, S, Walusuna, L, Wang, JH, Wang, L, Wanyonyi, S, Weatherall, D, Wiladphaingern, S, Wilkinson, A, Wilson, D, Wu, MH, Wu, QQ, Wulff, K, Yellappan, D, Yuan, Y, Zaidi, S, Zainab, G, Zhang, JJ, Zhang, Y, Fung, Russell, Villar, Jose, Dashti, Ali, Ismail, Leila Cheikh, Staines-Urias, Eleonora, Ohuma, Eric O, Salomon, Laurent J, Victora, Cesar G, Barros, Fernando C, Lambert, Ann, Carvalho, Maria, Jaffer, Yasmin A, Noble, J Alison, Gravett, Michael G, Purwar, Manorama, Pang, Ruyan, Bertino, Enrico, Munim, Shama, Min, Aung Myat, McGready, Rose, Norris, Shane A, Bhutta, Zulfiqar A, Kennedy, Stephen H, Papageorghiou, Aris T, and Ourmazd, Abbas

Published
2020
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22. Fluorescence excitation emission matrices of human tissue: a system for in vivo measurement and method of data analysis

Author

Zuluaga, AF, Utzinger, U, Durkin, A, Fuchs, H, Gillenwater, A, Jacob, R, Kemp, B, Fan, J, and Richards-Kortum, R

Subjects
fluorescence, reflectance, EEM, tissue, head and neck, neoplasia, Bioengineering, Clinical Research, Biotechnology, Analytical Chemistry, Mechanical Engineering
Abstract

We describe a system capable of measuring spatially resolved reflectance spectra from 380 to 950 nm and fluorescence excitation emission matrices from 330 to 500 nm excitation and 380 to 700 nm emission in vivo. System performance was compared to that of a standard scanning spectrofluorimeter. This 'FastEEM' system was used to interrogate human normal and neoplastic oral cavity mucosa in vivo. Measurements were made through a fiber-optic probe and require 4 min total measurement time. We present a method based on autocorrelation vectors to identify excitation and emission wavelengths where the spectra of normal and pathologic tissues differ most. The FastEEM system provides a tool with which to study the relative diagnostic ability of changes in absorption, scattering, and fluorescence properties of tissue.

Published
1999

37. Effect of Midtreatment PET/CT-Adapted Radiation Therapy With Concurrent Chemotherapy in Patients With Locally Advanced Non–Small-Cell Lung Cancer: A Phase 2 Clinical Trial

Author

Kong, Feng-Ming, Ten Haken, Randall K., Schipper, Matthew, Frey, Kirk A., Hayman, James, Gross, Milton, Ramnath, Nithya, Hassan, Khaled A., Matuszak, Martha, Ritter, Timothy, Bi, Nan, Wang, Weili, Orringer, Mark, Cease, Kemp B., Lawrence, Theodore S., and Kalemkerian, Gregory P.

Published
2017
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41. Non-touching confinement of ternary particle systems by electrostatic surface forces.

Author

Mitra, N., Kemp, B. A., Sarkar, T., and Sheppard, C. J.

Subjects
*TERNARY system, *SURFACE forces, *ELECTROSTATIC interaction, *POTENTIAL energy, *EQUILIBRIUM, *TOUCH
Abstract

We apply an exact analytical model to demonstrate that multiple particle systems can bind in nontouching, minimum energy equilibrium configurations. It is predicted that such systems may self-assemble due entirely to electrostatic interactions without the aid of external forces. We demonstrate the potential energy equilibria for ternary systems where the effective dipoles cancel and the anomalous electrostatic forces are described by interactions between higher order multipoles. [ABSTRACT FROM AUTHOR]

Published
2019
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46. Identification and validation of a linear protective neutralizing epitope in the β-pore domain of alpha toxin.

Author

Jon Oscherwitz and Kemp B Cease

Subjects
Medicine, Science
Abstract

The plethora of virulence factors associated with Staphylococcus aureus make this bacterium an attractive candidate for a molecularly-designed epitope-focused vaccine. This approach, which necessitates the identification of neutralizing epitopes for incorporation into a vaccine construct, is being evaluated for pathogens where conventional approaches have failed to elicit protective humoral responses, like HIV-1 and malaria, but may also hold promise for pathogens like S. aureus, where the elicitation of humoral immunity against multiple virulence factors may be required for development of an effective vaccine. Among the virulence factors employed by S. aureus, animal model and epidemiological data suggest that alpha toxin, a multimeric β-pore forming toxin like protective antigen from Bacillus anthracis, is particularly critical, yet no candidate neutralizing epitopes have been delineated in alpha toxin to date. We have previously shown that a linear determinant in the 2β2-2β3 loop of the pore forming domain of B. anthracis protective antigen is a linear neutralizing epitope. Antibody against this site is highly potent for neutralizing anthrax lethal toxin in vitro and for protection of rabbits in vivo from virulent B. anthracis. We hypothesized that sequences in the β-pore of S. aureus alpha toxin that share structural and functional homology to β-pore sequences in protective antigen would contain a similarly critical neutralizing epitope. Using an in vivo mapping strategy employing peptide immunogens, an optimized in vitro toxin neutralization assay, and an in vivo dermonecrosis model, we have now confirmed the presence of this epitope in alpha toxin, termed the pore neutralizing determinant. Antibody specific for this determinant neutralizes alpha toxin in vitro, and is highly effective for mitigating dermonecrosis and bacterial growth in a mouse model of S. aureus USA300 skin infection. The delineation of this linear neutralizing determinant in alpha toxin could facilitate the development of an epitope-focused vaccine against S. aureus.

Published
2015
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