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INTRODUCTION: Vitamin D (VD) deficiency is frequent in sickle cell disease (SCD) due to chronic inflammatory status, kidney and endothelial damage, hyperhemolysis and melanoderma. Currently, the supplementation of this nutrient in sickle cell patients is important due to its systemic and immunological action. Objectives: To analyze the impact of VD in children with SCD. METHODS: This is an integrative literature review, which analyzed studies, originally published in English and Portuguese, in the last ten years, in humans, using the MedLine, SciELO and LILACS databases as References. The search was performed by consulting the MeSH. The descriptors used were: "children"; "vitamin D"; "sickle cell anemia"; "supplementation". 32 articles were identified from the search phrase. When applying the inclusion criteria, nine articles were chosen for the study. RESULTS: Among the included articles, six evaluated the prevalence of VD deficiency in children with sickle cell anemia, and the other three reported on VD supplementation in children with sickle cell anemia. All studies showed that children treated with VD replacement had a decrease in emergency room visits and greater hemodynamic stability during treatments. CONCLUSION: Further randomized controlled trials should be carried out to identify the role of VD in quality of life and in the reduction of sickle cell morbidity. The contribution of this paper is to recognize that there is evidence about vitamin D outside of randomized controlled trials.

Objectives: The purpose of this study was to analyze the impact of COVID-19 on the use of blood components in an oncology hospital. Material and Methods: Retrospective cross-sectional quantitative nature cohort, with comparative analysis of blood component requests by an oncology hospital in the city of Juiz de Fora, Minas Gerais, Brazil, in 2019 and 2020. Results: There was a reduction of 14.36% in the requests for blood components at the oncology service in 2020 (p-value = 0,002), with a reduction of 27.33% for platelet concentrate (p-value = 0,006). The rate of attendance of Hemominas to requests for blood components at the oncology hospital was 97.99% in 2019 and 94.36% in 2020. Conclusion: The pandemic affected blood collection and supply due to the decrease in blood donors' attendance. The suspension of elective surgeries and the rational prescription of blood components allowed the rate of attendance maintenance by the blood bank. In this scenario, it is important to monitor the supply and demand for blood components in hospitals and apply strategies that optimize their use.