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Background: Clinical disease registries are useful for quality improvement in care, benchmarking standards, and facilitating research. Collaborative networks established thence can enhance national and international studies by generating more robust samples and credible data and promote knowledge sharing and capacity building. This report describes the methodology, baseline data, and prospects of the Nigeria Parkinson Disease Registry., Methods: This national registry was established in November 2016. Ethics approval was obtained for all sites. Basic anonymized data for consecutive cases fulfilling the United Kingdom Parkinson's Disease Brain Bank criteria (except the exclusion criterion of affected family members) are registered by participating neurologists via a secure registry website (www.parkinsonnigeria.com) using a minimal common data capture format., Results: The registry had captured 578 participants from 5 of 6 geopolitical zones in Nigeria by July 2019 (72.5% men). Mean age at onset was 60.3 ± 10.7 years; median disease duration (interquartile range) was 36 months (18-60.5 months). Young-onset disease (<50 years) represented 15.2%. A family history was documented in 4.5% and 7.8% with age at onset <50 and ≥ 50, respectively. The most frequent initial symptom was tremor (45.3%). At inclusion, 93.4% were on treatment (54.5% on levodopa monotherapy). Per-capita direct cost for the registry was $3.37., Conclusions: This is the first published national Parkinson's disease registry in sub-Saharan Africa. The registry will serve as a platform for development of multipronged evidence-based policies and initiatives to improve quality of care of Parkinson's disease and research engagement in Nigeria. © 2020 International Parkinson and Movement Disorder Society., (© 2020 International Parkinson and Movement Disorder Society.)

Background: The quality of care in the emergency room is an indirect indicator of the standard of healthcare delivery in a given health institution. Mortality in the emergency room may result from various factors including incompetence of the attending junior physicians, delays in presentation and inadequate facilities. The aim of the study is to highlight the causes of mortality, age and sex distribution of the deaths and the duration of admission before death among medical cases in the accident and emergency unit of the University of Port Harcourt Teaching Hospital., Methods: A one year (January to December, 2005) clinical audit of all adult medical admissions in the accident and emergency department of the University of Port Harcourt Teaching Hospital (UPTH)., Results: Of the 5304 admitted over the study period, 349 (6.8%) patients died. Two hundred and thirty three (66.8%) of these deaths were due to medical cases only. These medical deaths were made up of 126 males and 107 females giving a male to female ratio of 1.2:1. The presumed causes of deaths were stroke in 56(24.5%), HIV/AIDS in 53 (22.7%), sepsis in 20 (8.6%), while 14 (6.0%) died from meningitis. Ten patients (4.3%) died from diabetic ketoacidosis, and hepatic encephalopathy and tetanus were responsible for 10 (4.3%) and 7 (3.0%) deaths respectively., Conclusion: In the period studied, medical mortality was high in the accident and emergency room of UPTH. The major causes of deaths were cerebrovascular accidents and HIV/AIDS.