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549 results on '"Ikeda, Tadashi"'

5. Modifiers of the Risk of Diabetes for Long-Term Outcomes After Coronary Revascularization: CREDO-Kyoto PCI/CABG Registry

Author

Kimura, Takeshi, Shiomi, Hiroki, Matsuda, Mitsuo, Takeuchi, Yuzo, Mitsuoka, Hirokazu, Uegaito, Takashi, Nakagawa, Yoshihisa, Tamura, Toshihiro, Konishi, Takashi, Ootani, Seiji, Fujiwara, Hisayoshi, Takatsu, Yoshiki, Sato, Yukihito, Taniguchi, Ryoji, Kataoka, Kazuaki, Inoko, Moriaki, Nohara, Ryuji, Nakano, Kimisato, Miyamoto, Syoichi, Kunihiko, Nagai, Murakami, Tomoyuki, Takeda, Teruki, Ishida, Katsuya, Nobuyoshi, Masakiyo, Yamaji, Kyohei, Yasumoto, Hitoshi, Iwabuchi, Masashi, Ando, Kenji, Domei, Takenori, Kato, Masayuki, Tatami, Ryozo, Shirotani, Manabu, Hattori, Ryuichi, Kita, Toru, Furukawa, Yutaka, Ehara, Natsuhiko, Kihara, Yasuki, Eizawa, Hiroshi, Kato, Hiroshi, Ishii, Katsuhisa, Aoyama, Takeshi, Sakurai, Takahiro, Kawanami, Masaki, Suyama, Tamaki, Tada, Eiji, Tanaka, Masaru, Inada, Tsukasa, Uzui, Hiroyasu, Nakano, Akira, Lee, Jong-Dae, Onodera, Tomoya, Takizawa, Akinori, Ryuzo, Nawada, Shinoda, Eiji, Takahashi, Masaaki, Yamada, Miho, Horie, Minoru, Yamamoto, Takashi, Takashima, Hiroyuki, Sakai, Hiroshi, Tamura, Takashi, Toyofuku, Mamoru, Kotoura, Hajime, Miura, Akira, Takahashi, Mamoru, Matoba, Yoshiki, Takumi, Takuro, Tei, Chuwa, Hamasaki, Shuichi, Doi, Osamu, Kambara, Hirofumi, Kaburagi, Satoshi, Sakamoto, Hiroki, Tada, Tomohisa, Mitsudo, Kazuaki, Kadota, Kazushige, Tada, Takeshi, Miki, Shinji, Mizoguchi, Tetsu, Akira, Yoshida, Kaneda, Kazuhisa, Ogawa, Hisao, Sugamura, Koichi, Sugiyama, Seigo, Doyama, Kiyoshi, Araki, Makoto, Suwa, Satoru, Sakata, Ryuzo, Ikeda, Tadashi, Marui, Akira, Minatoya, Kenji, Yamazaki, Kazuhiro, Onoe, Masahiko, Ogawa, Tatsuya, Yamanaka, Kazuo, Iwakura, Atsushi, Ohno, Nobuhisa, Fujiwara, Keiichi, Hanyu, Michiya, Soga, Kinji, Matsushita, Tsutomu, Nishiwaki, Noboru, Yoshida, Yuichi, Tamura, Nobushige, Okada, Yukikatsu, Nasu, Michihiro, Koyama, Tadaaki, Nakayama, Shogo, Tanaka, Kuniyoshi, Koshiji, Takaaki, Morioka, Koichi, Shimamoto, Mitsuomi, Yamazaki, Fumio, Terai, Yasuhiko, Nishizawa, Junichiro, Aota, Masaki, Kanemitsu, Naoki, Hara, Hiroyuki, Tabata, Takafumi, Imoto, Yutaka, Yamamoto, Hiroyuki, Matsuda, Katsuhiko, Nara, Masafumi, Tsuneyoshi, Hiroshi, Komiya, Tatsuhiko, Nakajima, Hiroyuki, Esaki, Jiro, Kawasuji, Michio, Moriyama, Syuji, Tambara, Keiichi, Arimura, Sakiko, Fujino, Yumika, Hanazawa, Miya, Hibi, Chikako, Kato, Risa, Kinoshita, Yui, Kitagawa, Kumiko, Kitamura, Masayo, Kuwahara, Takahiro, Sachiko, Maeda, Miki, Izumi, Minematsu, Saeko, Nishida, Satoko, Okamoto, Naoko, Saeki, Asuka, Sasae, Hitomi, Sato, Yuki, Takahashi, Asuka, Takinami, Emi, Tezuka, Saori, Tsuda, Marina, Tsumori, Miyuki, Uchida, Yuriko, Yamamoto, Yuko, Yamauchi, Misato, Yamazaki, Itsuki, Yoshimoto, Mai, Abe, Mitsuru, Fuki, Masayuki, Hayano, Mamoru, Kato, Eri, Kato, Yoshihiro, Matsumura-Nakano, Yukiko, Nakajima, Tetsu, Nakatsuma, Kenji, Natsuaki, Masahiro, Takeji, Yasuaki, Tazaki, Junichi, Tokushige, Akihiro, Watanabe, Hiroki, Yaku, Hidenori, Yamamoto, Erika, Yamamoto, Ko, Yamashita, Yugo, Yoshikawa, Yusuke, Morimoto, Takeshi, Kato, Eri T., Imada, Kazuaki, Nishikawa, Ryusuke, Mabuchi, Hiroshi, and Soga, Yoshiharu

Published
2022
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15. Using the DNA Integrity Number to Analyze DNA Quality in Specimens Collected from Liquid-Based Cytology after Fine-Needle Aspiration of Breast Tumors and Lesions.

Author

Hoshino, Akiyoshi, Oana, Yoshiyasu, Ohi, Yasuyo, Maeda, Yukari, Omori, Masako, Takada, Yuki, Ikeda, Tadashi, Sotome, Keiichi, Maeda, Hinako, Yanagisawa, Takako, Takeuchi, Osamu, Kuronuma, Satoshi, Sangai, Takafumi, Shibahara, Yukiko, Murakumo, Yoshiki, Saegusa, Makoto, Kanomata, Naoki, Nagasawa, Satoi, Yamaguchi, Rin, and Yoshida, Masayuki

Published
2024
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16. Pleurodesis using OK-432 for persistent pleural effusion after cardiac surgery in the neonatal period or early infancy.

Author

Nakata, Tomohiro, Tachi, Maiko, Yasuda, Kenji, Nakashima, Shigeki, Ikeda, Tadashi, Minatoya, Kenji, and Oda, Teiji

Abstract

Objective: To evaluate the efficacy of pleurodesis using OK-432 after cardiac surgery in the neonatal period or early infancy. Methods: We retrospectively reviewed the data of 11 consecutive patients who underwent cardiac surgery in the neonatal period or early infancy and pleurodesis using OK-432 for persistent postoperative pleural effusion in two institutions. Results: The median age at surgery was 8 days (interquartile range [IR], 2–18) with a body weight of 2.84 kg (IR, 2.30–3.07). The maximum amount of pleural drainage before pleurodesis was 94.7 (IR, 60.2–107.7) ml/kg/day. Pleurodesis was initiated at postoperative day 20 (IR, 17–22) and performed in bilateral pleural spaces in seven patients and unilateral in four. The median numbers of injection were 4 (IR, 3–6) times per patient and 3 (IR, 2–3) times per pleural space. In 10 patients, pleural effusion was decreased effectively, and drainage tubes were removed without reaccumulation within 15 (IR, 12–28) days after initial pleurodesis. However, in one patient, with severe lymphedema, pleural effusion was uncontrollable, resulting in death due to sepsis. Adverse events were observed in nine patients; temporal deterioration of lung compliance and arterial blood gas occurred in two, insufficient drainage requiring new chest tube(s) in five, temporal atrial tachyarrhythmia in one, and lymphedema in four. Conclusions: Pleurodesis using OK-432 is effective and reliable for persistent postoperative pleural effusion in neonates and early infants. Most of the complications, which derived from inflammatory reactions, were temporary and controllable. However, severe lymphedema is difficult to control. [ABSTRACT FROM AUTHOR]

Published
2024
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17. Managing Foreign R&D in China

Author

von Zedtwitz, Maximilian, Ikeda, Tadashi, Gong, Li, Carpenter, Richard, and Hämäläinen, Seppo

Published
2018

23. Serum lipid and bone metabolism effects of Toremifene vs. Letrozole as adjuvant therapy for postmenopausal early breast cancer patients: results of a multicenter open randomized study

Author

Shien, Tadahiko, Doihara, Hiroyoshi, Sato, Nobuaki, Anan, Keisei, Komaki, Kansei, Miyauchi, Keisuke, Yanagita, Yasuhiro, Fujisawa, Tomomi, Mitsuyama, Shoshu, Kanbayashi, Chizuko, Kusama, Mikihiro, Kimura, Morihiko, Jinno, Hiromitsu, Sano, Muneaki, and Ikeda, Tadashi

Published
2017
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24. Surgical treatment for a child with traumatic ventricular septal rupture and ventricular aneurysm.

Author

Tomotsuka, Sanae, Ikeda, Tadashi, Ide, Yujiro, Baba, Shiro, Hirata, Takuya, and Minatoya, Kenji

Abstract

A five-year-old boy was diagnosed with the ventricular septal rupture and ventricular aneurysm after blunt chest trauma in child abuse. Because of the intractable heart failure, he underwent operation in subacute period. Postoperative course was uneventful. The blunt cardiac injury in children can be caused by mild trauma and can be lethal. Surgical intervention should be considered when the clinical condition is unstable. [ABSTRACT FROM AUTHOR]

Published
2024
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29. Japanese Society of Clinical Oncology clinical practice guidelines 2010 for antiemesis in oncology: executive summary

Author

Takeuchi, Hideki, Saeki, Toshiaki, Aiba, Keisuke, Tamura, Kazuo, Aogi, Kenjiro, Eguchi, Kenji, Okita, Kenji, Kagami, Yoshikazu, Tanaka, Ryuhei, Nakagawa, Kazuhiko, Fujii, Hirofumi, Boku, Narikazu, Wada, Makoto, Akechi, Tatsuo, Udagawa, Yasuhiro, Okawa, Yutaka, Onozawa, Yusuke, Sasaki, Hidenori, Shima, Yasuo, Shimoyama, Naohito, Takeda, Masayuki, Nishidate, Toshihiko, Yamamoto, Akifumi, Ikeda, Tadashi, and Hirata, Koichi

Published
2016
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31. Comparison of living-donor lobar lung transplantation and cadaveric lung transplantation for pulmonary hypertension.

Author

Kayawake, Hidenao, Tanaka, Satona, Yamada, Yoshito, Baba, Shiro, Kinoshita, Hideyuki, Yamazaki, Kazuhiro, Ikeda, Tadashi, Minatoya, Kenji, Yutaka, Yojiro, Hamaji, Masatsugu, Ohsumi, Akihiro, Nakajima, Daisuke, and Date, Hiroshi

Subjects
LUNG transplantation, PREHABILITATION, PULMONARY edema, PULMONARY artery, LUNG diseases, KIDNEY transplantation, LIFESAVING
Abstract

OBJECTIVES: Living-donor lobar lung transplantation (LDLLT) is a life-saving procedure for critically ill patients with various lung diseases, including pulmonary hypertension (PH). However, there are concerns regarding the development of heart failure with pulmonary oedema after LDLLT in which only 1 or 2 lobes are implanted. This study aimed to compare the preoperative conditions and postoperative outcomes of LDLLT with those of cadaveric lung transplantation (CLT) in PH patients. METHODS: Between 2008 and 2021, 34 lung transplants for PH, including 12 LDLLTs (5 single and 7 bilateral) and 22 bilateral CLTs, were performed. Preoperative variables and postoperative outcomes were retrospectively compared between the 2 procedures. RESULTS: Based on the preoperative variables of less ambulatory ability (41.7% vs 100%, P < 0.001), a higher proportion of World Health Organization class 4 (83.3% vs 18.2%, P < 0.001) and higher mean pulmonary artery pressure (74.4 vs 57.3 mmHg, P = 0.040), LDLLT patients were more debilitated than CLT patients. Nevertheless, hospital death was similar between the 2 groups (8.3% vs 9.1%, P > 0.99, respectively). Furthermore, the 5-year overall survival rate was similar between the 2 groups (90.0% vs 76.3%, P = 0.489). CONCLUSIONS: Although LDLLT patients with PH had worse preoperative conditions and received smaller grafts than CLT patients, LDLLT patients demonstrated similar perioperative outcomes and prognoses as CLT patients. LDLLT is a viable treatment option for patients with PH. Lung transplantation (LTx) has been performed as the final option for saving the lives of patients with end-stage pulmonary diseases with satisfactory outcomes, and the number of LTx procedures performed has been gradually increasing [1]. [ABSTRACT FROM AUTHOR]

Published
2023
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32. 2013 clinical practice guidelines (The Japanese Breast Cancer Society): history, policy and mission

Author

Mukai, Hirofumi, Noguchi, Shinzaburo, Akiyama, Futoshi, Inaji, Hideo, Iwase, Hirotaka, Horiguchi, Jun, Kurebayashi, Junichi, Hirata, Koichi, Toi, Masakazu, Kurosumi, Masafumi, Kohno, Norio, Nishimura, Reiki, Nakamura, Seigo, Imoto, Shigeru, Iwase, Takuji, Endo, Tokiko, Saeki, Toshiaki, Ogawa, Yasuhiro, Ito, Yoshinori, Tokuda, Yutaka, and Ikeda, Tadashi

Published
2015
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37. MANAGING FOREIGN R&D IN CHINA

Author

von Zedtwitz, Maximilian, Ikeda, Tadashi, Li Gong, Carpenter, Richard, and Hämäläinen, Seppo

Published
2007

38. Pioglitazone-incorporated microspheres targeting macrophage polarization alleviates cardiac dysfunction after myocardial infarction.

Author

Konegawa, Yasushi, Kuwahara, Toshie, Jo, Jun-Ichiro, Murata, Kozue, Takeda, Takahide, Ikeda, Tadashi, Minatoya, Kenji, Masumoto, Hidetoshi, and Tabata, Yasuhiko

Subjects
HEART diseases, MYOCARDIAL infarction, VENTRICULAR remodeling, MACROPHAGES, MYOCARDIAL reperfusion, HEART size, MACROPHAGE inflammatory proteins, TARGETED drug delivery
Abstract

Open in new tab Download slide OBJECTIVES Excessive and chronic inflammation after a myocardial infarction (MI) is associated with left ventricular remodelling and impaired cardiac function. Among inflammatory cells, macrophages play a critical role in polarizing proinflammatory M1 or the reparative M2 subtype. Pioglitazone (PGZ) is reported to regulate macrophage polarization to the M2 subtype. Our goal was to validate the therapeutic effects and the mechanisms of PGZ utilizing a drug delivery system. METHODS Poly L-lactic-co-glycolic acid microspheres (MS) incorporating PGZ were prepared. To validate the therapeutic potential of PGZ-MS, Sprague-Dawley rats were subjected to permanent left coronary artery ligation to induce an MI. Placebo-MS (100 μg) or PGZ-MS (100 μg) was injected to the infarct region just after induction. Cardiac function and size were assessed by echocardiography. At 28 days after surgery, the rats were sacrificed, and the excised hearts were evaluated histologically. RESULTS Sustained release of PGZ from the PGZ-MS was confirmed in vitro. PGZ-MS significantly rehabilitated cardiac dysfunction after an MI (fractional shortening: MI vs MI+placebo-MS vs MI+PGZ-MS, 24.4 ± 1.1 vs 24.3 ± 1.6 vs 32.2 ± 1.4%; P = 0.0035) with reverse remodelling. Immunohistochemical analyses revealed that PGZ-MS enhanced macrophage polarization (ratio of M2 subtype: 0.39 ± 0.03 vs 0.42 ± 0.02 vs 0.54 ± 0.02; P = 0.0004) and attenuated apoptosis of cardiomyocytes in the ischaemic border zone. CONCLUSIONS We confirmed macrophage polarization by sustained release of PGZ, which resulted in amelioration of adverse left ventricular remodelling and cardiac dysfunction. Drug delivery system-based macrophage polarization might serve as a promising strategy in cardiac regenerative therapy for ischaemic heart disease. (241 words) [ABSTRACT FROM AUTHOR]

Published
2022
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42. Novel operative technique for Scimitar syndrome: Posterior flap technique.

Author

Maeda, Toshi, Yoshizawa, Kosuke, Mori, Otohime, Sakazaki, Hisanori, and Ikeda, Tadashi

Abstract

Various surgical techniques have been reported for Scimitar syndrome, because of the heterogenous anatomy of the disease. We developed a novel surgical method to repair Scimitar syndrome, in which, a new pulmonary venous route is constructed behind the inferior vena cava using autologous flaps of the inferior vena cava and the interatrial septum. An adult case of Scimitar syndrome was repaired by this method with good results. [ABSTRACT FROM AUTHOR]

Published
2023
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44. Preoperative systemic therapy in locoregional management of early breast cancer: highlights from the Kyoto Breast Cancer Consensus Conference

Author

Toi, Masakazu, Benson, John R., Winer, Eric P., Forbes, John F., von Minckwitz, Gunter, Golshan, Mehra, Robertson, John F. R., Sasano, Hironobu, Cole, Bernard F., Chow, Louis W. C., Pegram, Mark D., Han, Wonshik, Huang, Chiun-Sheng, Ikeda, Tadashi, Kanao, Shotaro, Lee, Eun-Sook, Noguchi, Shinzaburo, Ohno, Shinji, Partridge, Ann H., Rouzier, Roman, Tozaki, Mitsuhiro, Sugie, Tomoharu, Yamauchi, Akira, and Inamoto, Takashi

Published
2012
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