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330 results on '"Holm, Hilma"'

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1. Integrative common and rare variant analyses provide insights into the genetic architecture of liver cirrhosis.

2. Homozygosity for a stop-gain variant in CCDC201 causes primary ovarian insufficiency

3. The correlation between CpG methylation and gene expression is driven by sequence variants

4. X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in genes regulated by androgen response elements.

5. Genetic insights into resting heart rate and its role in cardiovascular disease.

6. Sequence variants influencing the regulation of serum IgG subclass levels

7. Loss-of-function variants in ITSN1 confer high risk of Parkinson’s disease

8. Start codon variant in LAG3 is associated with decreased LAG-3 expression and increased risk of autoimmune thyroid disease

9. Predicting the presence of coronary plaques featuring high-risk characteristics using polygenic risk scores and targeted proteomics in patients with suspected coronary artery disease

10. Variant in the synaptonemal complex protein SYCE2 associates with pregnancy loss through effect on recombination

11. Genetics and epidemiology of mutational barcode-defined clonal hematopoiesis

12. Rare variants with large effects provide functional insights into the pathology of migraine subtypes, with and without aura

13. Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target

14. Author Correction: Large-scale plasma proteomics comparisons through genetics and disease associations

15. A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids

16. Large-scale plasma proteomics comparisons through genetics and disease associations

17. Physical and cognitive impact following SARS-CoV-2 infection in a large population-based case-control study

18. Publisher Correction: Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality

19. Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality

20. The power of genetic diversity in genome-wide association studies of lipids

21. Genome-wide meta-analysis identifies 93 risk loci and enables risk prediction equivalent to monogenic forms of venous thromboembolism

22. Complex effects of sequence variants on lipid levels and coronary artery disease

23. Abstract 18244: A Multi-Ancestry GWAS of Calcific Aortic Stenosis Among 2.7 Million Individuals

24. Abstract 16950: The Genetic Basis of Atrial Fibrillation in a Large-Scale Multi-Ancestry Sample

25. Discovery and systematic characterization of risk variants and genes for coronary artery disease in over a million participants

26. Multiomics study of nonalcoholic fatty liver disease

27. The sequences of 150,119 genomes in the UK Biobank

28. Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria.

29. Genetic loci and prioritization of genes for kidney function decline derived from a meta-analysis of 62 longitudinal genome-wide association studies

30. Reconstruction of a large-scale outbreak of SARS-CoV-2 infection in Iceland informs vaccination strategies

31. Genetic architecture of band neutrophil fraction in Iceland

32. HLA alleles, disease severity, and age associate with T-cell responses following infection with SARS-CoV-2

33. Population-level deficit of homozygosity unveils CPSF3 as an intellectual disability syndrome gene

34. Differential and shared genetic effects on kidney function between diabetic and non-diabetic individuals

35. Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

37. Obesity Variants in the GIPR Gene Are not Associated With Risk of Fracture or Bone Mineral Density.

38. Large-scale integration of the plasma proteome with genetics and disease

39. Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes

40. PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity

41. Genetic propensities for verbal and spatial ability have opposite effects on body mass index and risk of schizophrenia

42. Distinction between the effects of parental and fetal genomes on fetal growth

43. Long-read sequencing of 3,622 Icelanders provides insight into the role of structural variants in human diseases and other traits

44. Molecular benchmarks of a SARS-CoV-2 epidemic

45. The genetic architecture of age-related hearing impairment revealed by genome-wide association analysis

46. A genome-wide meta-analysis uncovers six sequence variants conferring risk of vertigo

47. Genetic variants associated with platelet count are predictive of human disease and physiological markers

48. Predicting the probability of death using proteomics

49. Lipoprotein(a) Concentration and Risks of Cardiovascular Disease and Diabetes

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