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Background: The recurring psychological, behavioural, and physical symptoms of premenstrual tension syndrome (PTS) are related to the luteal phase of the menstrual cycle. Its development may be influenced by hormonal influences. Objectives: To investigate the effects of catecholamines on PTS and possible improvements upon using pharmacological treatments. Patients and methods: After agreement of participants and ethical committee approval, this randomized controlled trial enrolled 60 obese women with PTS who were split into younger (18-39 years) and older (40-48 years) age groups in comparison to an age-matched healthy control group. All of the study participants' serum levels of adrenaline (epinephrine), and norepinephrine were measured. Utilizing pertinent rating scales, a few psychosomatic PTS symptoms (headache, backache, and stomach bloating) were also assessed. Results: Compared to the control group, obese women with PTS had significantly higher serum levels of adrenaline, and noradrenaline (p

Abstract Background Premenstrual syndrome (PMS) is a clinical condition characterized by recurrent moderate-to-severe affective, physical, and behavioral symptoms during the menstrual cycle. The present study aimed to assess the relation between metabolic syndrome (MetS) and symptoms severity in patients with premenstrual syndrome (PMS). This multicentric propensity score matched analysis included 300 women with PMS. They comprised 150 women with MetS and 150 women without MetS. Diagnosis of PMS was based on the validated Arabic version of Premenstrual Symptoms Screening Tool (PSST). For the diagnosis of MetS, we adopted the Harmonized Joint Scientific Statement (HJSS) on metabolic syndrome recommendations. Results The present study included 300 patients with PMS. They comprised 150 patients with MetS and 150 patients without MetS. Comparison between the studied groups regarding the demographic and clinical data showed that patients with MetS had significantly higher BMI (30.5 ± 3.0 versus 25.2 ± 3.5 kg/m2, p