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In the analysis of petroleum reservoirs, one of the most challenging problems is to use inverse theory in the search for an optimal parameterization of the reservoir. Generally, scientists approach this problem by computing a sensitivity matrix and then perform a singular value decomposition in order to determine the number of degrees of freedom i.e. the number of independent parameters necessary to specify the configuration of the system. Here we propose a complementary approach: it uses the concept of refinement indicators to select those degrees which have the greatest sensitivity to an objective function quantifying the mismatch between measured and simulated data. We apply this approach to the problem of data integration for petrophysical reservoir charaterization where geoscientists are currently working with multimillion cell geological models. Data integration may be performed by gradually deforming (by a linear combination) a set of these multimillion grid geostatistical realizations during the optimization process. The inversion parameters are then reduced to the number of coefficients of this linear combination. However, there is an infinity of geostatistical realizations to choose from which may not be efficient regarding operational constraints. Following our new approach, we are able through a single objective function evaluation to compute refinement indicators that indicate which realizations might improve the iterative geological model in a significant way. This computation is extremely fast as it implies a single gradient computation through the adjoint state approach and dot products. Using only the most sensitive realizations from a given set, we are able to resolve quicker the optimization problem case. We applied this methodology to the integration of interference test data into 3D geostatistical models. [ABSTRACT FROM AUTHOR]