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Your search keyword '"Gournay, Veronique"' showing total 19 results
Start Over Author "Gournay, Veronique" Publication Type Academic Journals
19 results on '"Gournay, Veronique"'

1. Description of 214 cases of autoimmune congenital heart block: Results of the French neonatal lupus syndrome

Author

Bezanahary, Holy, Bienvenu, Boris, Blaison, Gilles, Blanche, Philippe, Bonnotte, Bernard, Cathebras, Pascal, Christides, Christine, Cohen, Fleur, Cohen, Laurence, Devaud, Edouard, Diot, Elisabeth, Duhaut, Pierre, Dulac, Yves, Godeau, Bertrand, Gournay, Véronique, Gronier, Céline, Guillevin, Loïc, Hamidou, Mohamed, Haroche, Julien, Hayem, Gilles, Heitz, François, Isnard, Richard, Jallouli, Moez, Korganow, Anne-Sophie, Le Jeunne, Claire, Lhote, François, Lucron, Hugues, Lusson, Jean-René, Magnier, Suzel, Ninet, Jacques, Pangaud, Nicolas, Papo, Thomas, Pellegrin, Jean-Luc, Pennaforte, Jean Loup, Pouchot, Jacques, Sarrot-Reynauld, Françoise, Schleinitz, Nicolas, Seve, Pascal, Stos, Bertrand, Vital-Durand, Denis, Wechsler, Bertrand, Levesque, Kateri, Morel, Nathalie, Maltret, Alice, Baron, Gabriel, Masseau, Agathe, Orquevaux, Pauline, Piette, Jean-Charles, Barriere, Francois, Le Bidois, Jérome, Fermont, Laurent, Fain, Olivier, Theulin, Arnaud, Sassolas, Francois, Pezard, Philippe, Amoura, Zahir, Guettrot-Imbert, Gaëlle, Le Mercier, Delphine, Georgin-Lavialle, Sophie, Deligny, Christophe, Hachulla, Eric, Mouthon, Luc, Ravaud, Philippe, Villain, Elisabeth, Bonnet, Damien, and Costedoat-Chalumeau, Nathalie

Published
2015
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3. Abstention or intervention for isolated hypotension in the first 3 days of life in extremely preterm infants: association with short-term outcomes in the EPIPAGE 2 cohort study

Author

Durrmeyer, Xavier, Marchand-Martin, Laetitia, Porcher, Raphaël, Gascoin, Geraldine, Roze, Jean-Christophe, Storme, Laurent, Favrais, Geraldine, Ancel, Pierre-Yves, Cambonie, Gilles, Cambonie, Gilles, Rozé, Jean-Christophe, Ancel, Pierre-Yves, Marchand-Martin, Laetitia, Durox, Mélanie, Gournay, Veronique, Durrmeyer, Xavier, Storme, Laurent, Porcher, Raphael, Morville, Patrice, Brissaud, Olivier, Truffert, Patrick, Bouissou, Antoine, Ligi, Isabelle, Marcoux, Marie-Odile, Cneude, Fabrice, Gascoin, Geraldine, Thiriez, Gerard, Patural, Hugues, Madeleneau, Doriane, Burguet, Antoine, and Pladys, Patrick

Published
2017
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12. Search for Rare Copy-Number Variants in Congenital Heart Defects Identifies Novel Candidate Genes and a Potential Role for FOXC1 in Patients With Coarctation of the Aorta.

Author

Sanchez-Castro, Marta, Eldjouzi, Hadja, Charpentier, Eric, Busson, Pierre-Francois, Hauet, Quentin, Lindenbaum, Pierre, Delasalle-Guyomarch, Beatrice, Baudry, Adrien, Pichon, Olivier, Pascal, Cecile, Lefort, Bruno, Bajolle, Fanny, Pezard, Philippe, Schott, Jean-Jacques, Dina, Christian, Redon, Richard, Gournay, Veronique, Bonnet, Damien, and Le Caignec, Cedric

Subjects
CONGENITAL heart disease, POLYMERASE chain reaction, DISEASE risk factors
Abstract

Background--Congenital heart defects are the most frequent malformations among newborns and a frequent cause of morbidity and mortality. Although genetic variation contributes to congenital heart defects, their precise molecular bases remain unknown in the majority of patients. Methods and Results--We analyzed, by high-resolution array comparative genomic hybridization, 316 children with sporadic, nonsyndromic congenital heart defects, including 76 coarctation of the aorta, 159 transposition of the great arteries, and 81 tetralogy of Fallot, as well as their unaffected parents. We identified by array comparative genomic hybridization, and validated by quantitative real-time polymerase chain reaction, 71 rare de novo (n=8) or inherited (n=63) copy-number variants (CNVs; 50 duplications and 21 deletions) in patients. We identified 113 candidate genes for congenital heart defects within these CNVs, including BTRC, CHRNB3, CSRP2BP, ERBB2, ERMARD, GLIS3, PLN, PTPRJ, RLN3, and TCTE3. No de novo CNVs were identified in patients with transposition of the great arteries in contrast to coarctation of the aorta and tetralogy of Fallot (P=0.002; Fisher exact test). A search for transcription factor binding sites showed that 93% of the rare CNVs identified in patients with coarctation of the aorta contained at least 1 gene with FOXC1-binding sites. This significant enrichment (P<0.0001; permutation test) was not observed for the CNVs identified in patients with transposition of the great arteries and tetralogy of Fallot. We hypothesize that these CNVs may alter the expression of genes regulated by FOXC1. Foxc1 belongs to the forkhead transcription factors family, which plays a critical role in cardiovascular development in mice. Conclusions--These data suggest that deregulation of FOXC1 or its downstream genes play a major role in the pathogenesis of coarctation of the aorta in humans. [ABSTRACT FROM AUTHOR]

Published
2016
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13. Neurodevelopmental Outcome at 2 Years of Age according to Patent Ductus Arteriosus Management in Very Preterm Infants.

Author

Bourgoin, Laura, Cipierre, Cecile, Hauet, Quentin, Basset, Helene, Gournay, Veronique, Rozé, Jean-Christophe, Flamant, Cyril, and Gascoin, Geraldine

Subjects
PATENT ductus arteriosus, HEART blood-vessel abnormalities, CONGENITAL heart disease, PREMATURE infant diseases, IBUPROFEN, NEURODEVELOPMENTAL treatment, COGNITIVE ability, THERAPEUTICS
Abstract

Background: Patent ductus arteriosus (PDA) is a condition frequently found in very preterm infants, and its treatment remains a subject of debate. Furthermore, there are only a few studies available that have examined the impact of these treatments on the neurological outcome of the patient. Objective: To evaluate the neurodevelopmental outcome of PDA treatment on preterm infants born between 24+0 and 28+6 weeks of gestation. Methods: We conducted an observational multicentric cohort study (LIFT Cohort). We compared three groups of patients according to their PDA treatment strategy: medical treatment with ibuprofen, surgical ligation, and no treatment. The neurodevelopmental outcome was assessed with a physical examination and cognitive function evaluation at 2 years of age. A propensity score was used to reduce bias in the analysis. Results: Between 2003 and 2011, 857 infants (91.3%) were evaluated at 2 years of corrected age and included in the analysis: 248 received ibuprofen treatment (29%), 104 had PDA surgical ligation (12%), and 505 did not receive any PDA treatment (59%). Surgical ligation of PDA was significantly associated with neurodevelopmental impairment at 2 years of age (adjusted odds ratio = 2.2; 95% confidence interval: 1.4-3.4). Conclusion: We found an association between PDA surgical ligation and a nonoptimal neurodevelopmental outcome at 2 years of age for preterm infants born before 29 weeks of gestation. These results suggest that if surgical ligation is unavoidable, particular attention should be given to the patient's neurodevelopmental follow-up. © 2016 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]

Published
2016
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17. 341 Parental electrocardiographic screening identifies a high degree of inheritance for congenital and childhood non-immune isolated atrioventricular block

Author

Baruteau, Alban-Elouen, Behaghel, Albin, Fouchard, Swanny, Dina, Christian, Villain, Elisabeth, Thambo, Jean-Benoit, Marçon, François, Gournay, Véronique, Rouault, Francis, Chantepie, Alain, Guillaumont, Sophie, Godart, François, Bonnet, Caroline, Fraisse, Alain, Schleich, Jean-Marc, Lusson, Jean-René, Dulac, Yves, Martins, Raphaël, Chatel, Stéphanie, Schott, Jean-Jacques, Daubert, Jean-Claude, Le Marec, Hervé, Mabo, Philippe, and Probst, Vincent

Published
2012
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18. 325 Clinical presentation and long-term clinical outcomes of non immune, isolated atrioventricular block diagnosed in utero or early childhood

Author

Baruteau, Alban-Elouen, Villain, Elisabeth, Thambo, Jean-Benoit, Marçon, François, Gournay, Véronique, Rouault, Francis, Chantepie, Alain, Guillaumont, Sophie, Godart, François, Bonnet, Caroline, Fraisse, Alain, Schleich, Jean-Marc, Lusson, Jean-René, Dulac, Yves, Fouchard, Swanny, Chatel, Stéphanie, Behaghel, Albin, Leclercq, Christophe, Daubert, Jean-Claude, Schott, Jean-Jacques, Le Marec, Hervé, Mabo, Philippe, and Probst, Vincent

Published
2012
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19. 294 Clinical presentation and long-term outcome of non immune and isolated atrioventricular block when congenital or diagnosed during childhood: a French multicentric study on 141 patients

Author

Baruteau, Alban-Elouen, Schott, Jean-Jacques, Villain, Elisabeth, Maltret, Alice, Thambo, Jean-Benoit, Bretonneau, Alexandre, Marçon, François, Rouault, Francis, Gournay, Véronique, Chantepie, Alain, Guillaumont, Sophie, Godart, François, Bonnet, Caroline, Fraisse, Alain, Schleich, Jean-Marc, Lusson, Jean-René, Dulac, Yves, Daubert, Jean-Claude, Le Marec, Hervé, Mabo, Philippe, and Probst, Vincent

Published
2011
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