19 results on '"Geisbüsch, Andreas"'
Search Results
2. Hypofractionated proton and carbon ion beam radiotherapy for sacrococcygeal chordoma (ISAC): An open label, randomized, stratified, phase II trial
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Seidensaal, Katharina, Froehlke, Andreas, Lentz-Hommertgen, Adriane, Lehner, Burkhard, Geisbuesch, Andreas, Meis, Jan, Liermann, Jakob, Kudak, Andreas, Stein, Katharina, Uhl, Matthias, Tessonnier, Thomas, Mairani, Andrea, Debus, Juergen, and Herfarth, Klaus
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- 2024
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3. Differences in Success Rate of Two-Stage Revision for Periprosthetic Joint Infection of the Knee Depending on the Applied Definition
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Lunz, Andre, Geisbüsch, Andreas, Omlor, Georg W., Horsch, Axel, Renkawitz, Tobias, and Lehner, Burkhard
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- 2024
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4. Electromagnetic bone segment tracking in multiplanar osteotomies: A saw bone study.
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Geisbüsch, Andreas, Gramer, Carina, Dreher, Thomas, Hagen, Niclas, Hagmann, Sébastien, Renkawitz, Tobias, and Götze, Marco
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TREATMENT effectiveness , *ORTHOPEDIC surgery , *LARGE deviations (Mathematics) , *GONIOMETERS , *ANGLES , *SAWS - Abstract
Computer assisted orthopedic surgery is used to improve precision. Electro‐magnetic tracking has been shown to improve precision in mono‐planar derotational osteotomies. However, studies are lacking to investigate its use in multiplanar osteotomies. For this purpose, 60 complex (derotation and extension) osteotomies were performed in standardized sawbones. Correction amount was randomly planned before the procedures. In 30 bones, the amount of correction was determined intraoperatively using conventional goniometric measurement while in the other 30 bones electro‐magnetic tracking was used to guide the amount of correction. CT‐scans were done before and after the procedures in all bones and the amount of correction was determined to compare the precision of the two techniques. Electromagnetic tracking resulted in a precision of 2.25° ± 1.77° for derotation and 1.38° ± 1.29° for extension, while precision for the conventional method was significantly lower. There was a significant relationship between goniometer measurement deviation and the absolute angle change for derotation and extension measurements with larger deviations for greater angle changes. For the electro‐magnetic tracking, this correlation was observed only for derotation measurement. Electro‐magnetic tracking represents an accurate method to control complex, multiplanar corrective osteotomies with superior precision in comparison to conventional goniometric measurement. Further research is needed to investigate the in‐vivo accuracy and the effects on clinical outcome. [ABSTRACT FROM AUTHOR]
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- 2024
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5. Static spacers play a crucial role in the treatment of complex periprosthetic joint infections of the knee.
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Lunz, Andre, Omlor, Georg W., Voss, Moritz N., Geisbüsch, Andreas, Renkawitz, Tobias, and Lehner, Burkhard
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PROSTHESIS-related infections ,REIMPLANTATION (Surgery) ,TREATMENT effectiveness - Abstract
Purpose: To determine the superior spacer design, a growing number of studies are comparing treatment results between patients having been treated with articulating and static knee spacers in the setting of two‐stage revision for periprosthetic joint infection (PJI). In contrast, the primary objective of this study was to compare preoperative characteristics between patients from both spacer groups and examine whether significant differences were present prior to spacer implantation. Methods: This retrospective, single‐centre, cohort study examined the preoperative situation of 80 consecutive knee PJIs between 2017 and 2020. All patients underwent two‐stage revision, with 35 (44%) receiving an articulating and 45 (56%) a static spacer. Results: No significant differences were observed in terms of patient gender (p = 0.083), age (p = 0.666), comorbidity (p = 0.1) and preoperative clinical function (p = 0.246). Static spacers were significantly more often used in the presence of a periarticular fistula (p = 0.033), infection of a revision implant (p < 0.001), higher degree of bone loss (p < 0.001) and infection caused by a difficult‐to‐treat pathogen (p = 0.038). Complication and revision rates were similar for both spacer types during the interim period, while patients with articulating spacers demonstrated a superior clinical function (p < 0.001) during the interim period and after reimplantation. Conclusion: Static spacers are being utilised in significantly more complex and unfavourable preoperative scenarios. Therefore, a preoperative selection bias may be at least partially accountable for any disparities observed in postoperative outcomes. To achieve the best possible results, surgeons should know and respect the distinct indications of static and articulating spacers and consequently understand and use them as complementary surgical options. Level of Evidence: Level III. [ABSTRACT FROM AUTHOR]
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- 2024
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6. Pain in Adults With Cerebral Palsy After Single-Event Multilevel Surgery
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Götze, Marco, Geisbüsch, Andreas, Thielen, Mirjam, Döderlein, Leonhard, Wolf, Sebastian I., Dreher, Thomas, and Putz, Cornelia
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- 2022
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7. Regulation of WNT5A and WNT11 during MSC in vitro chondrogenesis: WNT inhibition lowers BMP and hedgehog activity, and reduces hypertrophy
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Diederichs, Solvig, Tonnier, Veronika, März, Melanie, Dreher, Simon I., Geisbüsch, Andreas, and Richter, Wiltrud
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- 2019
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8. Long-term results of multilevel surgery in adults with cerebral palsy
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Putz, Cornelia, Blessing, Ann- Kathrin, Erhard, Sarah, Fiethen, Katharina, Geisbüsch, Andreas, Niklasch, Mirjam, Döderlein, Leonhard, Wolf, Sebastian Immanuel, and Dreher, Thomas
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- 2019
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9. K-Wire Osteosynthesis for Arthrodesis of the Paediatric Foot Is a Good and Valid Procedure.
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Kreher, Jannes, Putz, Cornelia, Fackler, Susanne, Müller, Sebastian, Horsch, Axel, and Geisbüsch, Andreas
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ARTHRODESIS ,INTERNAL fixation in fractures ,INTRAMEDULLARY rods ,PEDIATRICS ,SUBTALAR joint ,CHILD patients ,CLUBFOOT - Abstract
Background: Foot deformities in children are common, and the majority can be treated conservatively. Nevertheless, there are deformities that require surgical treatment. These include rigid clubfeet, severe forms of pes planovalgus, pes cavus and several more. We retrospectively analysed the pseudarthrosis rate of surgical treatment of foot deformities with transcutaneous K-wire osteosynthesis in neurologically healthy children and adolescents. The aim of the study was to show that the results with K-wires are comparable to those with other osteosynthesis methods in the literature. Methods: A total of 46 paediatric patients aged 6 to 17 years treated between January 2010 and December 2015 met the inclusion criteria. Depending on the diagnosis, different surgical interventions were necessary. In clubfoot and pes planovalgus, representing n = 81, 70% of the whole collective triple arthrodesis with fusion of the talonavicular, calcaneocuboid and subtalar joints or Evans osteotomy was usually performed. Radiographs were taken at least 6 months post-surgery, and bony consolidation of the subtalar, talonavicular (TN), and calcaneocuboidal (CC) joints and the metatarsal I (MT I) osteotomy were assessed. If there was no evidence of fusion at this time, it was considered non-union. Results: In total, 117 arthrodesis procedures with K-wires were performed. Overall, 110 of the arthrodesis (94%) healed, and only 7 joints (6%) showed non-union (subtalar 0%, TN 7.7%, CC 6.5% and MT I 6.7%). All non-unions occurred in subjects with clubfoot deformities. No significant risk factors were observed. Conclusion: This study replicated the good consolidation rates reported in the literature with screws, plates, intramedullary nails or staples in arthrodesis of the adolescent foot in neurologically healthy subjects and confirmed the efficacy of K-wires. The main advantages of transcutaneous K-wire treatment are easy metal removal, lower osteosynthesis material costs and less concomitant damage. Further studies, especially randomised controlled trials, are needed to further investigate this topic. [ABSTRACT FROM AUTHOR]
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- 2023
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10. Computer assistance in femoral derotation osteotomy: a bottom-up approach
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Auer Christoph, Kallus Sebastian, Geisbüsch Andreas, Dreher Thomas, and Dickhaus Hartmut
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computer assisted surgery ,electromagnetic tracking ,femoral correction ,therapy monitoring ,Medicine - Abstract
Severe gait abnormalities in patients with cerebral palsy are often treated by correction osteotomy. The established procedure of femoral derotation osteotomy (FDO) has proven effective to realign femur anteversion. Nevertheless, studies have revealed that therapy outcome is subject to substantial inter-patient variability and systematic loss of correction. Our previous work suggests that practical limitations in FDO may significantly contribute to this effect. In this work, we propose a novel computer assisted measurement system to support FDO with objective measurement (desired accuracy: ∼ ± 3°) and continuous monitoring of derotation. A prototype system based on the clinically emerging electromagnetic tracking technology is demonstrated which incorporates technical and operational considerations to enable continuous measurement in OR conditions while preserving the conventional workflow without disruptions. In phantom studies, the achieved measurement accuracy (standard error ≅±1.6)∘$\cong\pm 1.6{}^{\circ})$ proved high potential and may hugely benefit the quality of surgical execution. Currently, the prototype system is assessed under OR conditions in an in-vivo study with CP patients. Early experience shows high appreciation among surgeons and good potential for future application.
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- 2016
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11. Electromagnetic tracking for femoral derotation osteotomy—an in vivo study
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Geisbüsch, Andreas, Auer, Christoph, Dickhaus, Hartmut, Putz, Cornelia, and Dreher, Thomas
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- 2017
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12. Extraosseous Ewing Sarcoma in Children: A Systematic Review and Meta-Analysis of Clinicodemographic Characteristics.
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Ghandour, Maher, Lehner, Burkhard, Klotz, Matthias, Geisbüsch, Andreas, Bollmann, Jakob, Renkawitz, Tobias, and Horsch, Axel
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MORTALITY risk factors ,ONLINE information services ,CHEST (Anatomy) ,META-analysis ,SYSTEMATIC reviews ,CANCER chemotherapy ,CANCER relapse ,TREATMENT effectiveness ,LEG ,DISEASE prevalence ,MEDLINE ,DEMOGRAPHY ,RADIOTHERAPY ,EWING'S sarcoma ,OVERALL survival ,DISEASE risk factors ,SYMPTOMS ,CHILDREN - Abstract
Background: We conducted this systematic review to provide comprehensive evidence on the prevalence, clinical features and outcomes of young extraosseous Ewing sarcoma (EES) cases. Methods: PubMed, Scopus, Web of Science, and Google Scholar were searched for articles reporting the occurrence of EES among children and adolescents (<21 years). The primary outcome included the rate of occurrence of EES among children and adolescents, while the secondary outcomes included the descriptive analyses of the demographic characteristics, tumor characteristics, and clinical outcomes of the affected cases. The data are reported as the effect size (ES) and its corresponding 95% confidence interval (CI). Results: A total of 29 studies were included. Twenty-four reported instances of childhood disease among all the EES cases [ES = 30%; 95%CI: 29–31%], while five studies reported extraosseous cases among the pediatric EES cases [ES = 22%; 95%CI: 13–31%]. The thorax is the most common location of childhood EES [33%; 95%CI: 20–46%] followed by the extremities [31%; 95%CI: 22–40%]. Concurrent chemotherapy and radiotherapy [57%; 95%CI: 25–84%] was the most commonly implemented management protocol in the pediatric EES cases. The rate of no evidence of disease and 5-year overall survival was 69% for both outcomes. Mortality occurred in 29% of cases, while recurrence and secondary metastasis occurred in 35% and 16% of cases, respectively. Conclusions: Our findings provide insight into the clinical features and outcomes of EES among children and adolescents. [ABSTRACT FROM AUTHOR]
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- 2022
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13. Mid-Term Results of Distal Femoral Extension and Shortening Osteotomy in Treating Flexed Knee Gait in Children with Cerebral Palsy.
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Geisbüsch, Andreas, Klotz, Matthias C. M., Putz, Cornelia, Renkawitz, Tobias, and Horsch, Axel
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FEMUR surgery ,KNEE physiology ,NEUROLOGICAL disorders ,OSTEOTOMY ,GAIT in humans ,FUNCTIONAL status ,GAIT disorders ,TREATMENT effectiveness ,PRE-tests & post-tests ,DIAGNOSIS ,BODY movement ,CEREBRAL palsy ,KINEMATICS ,LONGITUDINAL method ,DISEASE complications ,EVALUATION ,CHILDREN - Abstract
Background: Distal femoral extension and shortening osteotomy (DFESO) seems to be an effective method for the treatment of flexed knee gait in children with cerebral palsy. Nevertheless, studies investigating the mid- and long-term outcomes after such procedures are lacking in the literature. Therefore, the purpose of this study was to assess the mid-term outcomes regarding sagittal plane kinematics of the knee after DFESO with or without concomitant patella advancement. Furthermore, an evaluation of the postoperative course and possible recurrence of flexed knee gait was planned. Methods: In a prospective observational study, 19 patients (28 limbs; mean age 11.8 years (6.7–16.0 years)) were examined using 3-D gait analysis and clinical exam before (E
0 ) and at a mean of 38 months (E2 : 24–55 months) after surgery. Fifteen patients (22 limbs) had an additional first postoperative gait analysis (E1 ) after a mean of 14 (10–20) months after surgery. In these patients, the postoperative changes between the short-term and mid-term gait analyses were evaluated. Results: DFESO led to a significant decrease in flexed knee gait with an improvement in sagittal plane kinematics during the stance phase. In addition, a slightly increased anterior pelvic tilt was observed at E1 , and we found a tendency towards stiff knee gait with a decrease in mean knee flexion in swing at E2 . Conclusions: DFESO led to a significant improvement in flexed knee gait in children with cerebral palsy. The therapeutic effect seems to be lasting on mid-term follow-up with a slight overall tendency to recurrence. [ABSTRACT FROM AUTHOR]- Published
- 2022
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14. Femoral derotation osteotomy—Does intraoperative electromagnetic tracking reflect the dynamic outcome?
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Geisbüsch, Andreas, Götze, Marco, Putz, Cornelia, Dickhaus, Hartmut, and Dreher, Thomas
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CHILDREN with cerebral palsy , *GONIOMETERS , *OSTEOTOMY , *ELECTROMAGNETIC measurements - Abstract
Femoral derotation osteotomy (FDO) is a well‐established procedure for the correction of internal rotation gait in children with cerebral palsy. Various studies have demonstrated good results for FDO both in short‐term and long‐term evaluation with some describing recurrence and over‐ or under‐corrections. The present study evaluates the use of an objective intraoperative derotation measurement through electromagnetic tracking. We report the static and dynamic results of 11 cases with internal rotation gait (8 male, 3 female, mean age 22.2 years), that underwent FDO with intraoperative electromagnetic tracking and conventional goniometric measurement of the correction. The dynamic and static changes were assessed through three‐dimensional gait analysis after a mean of 12 months after surgery and rotational imaging preoperative and after a mean of eleven days postoperatively. Mean hip rotation in stance significantly decreased from 20.9° (SD 5.9) to 5.8° (SD 4.7°) after FDO. The mean amount of derotation quantified by electromagnetic tracking was 23.2° (16.5°–28.8°) and 25.1° (20.0°–33.0°) for goniometric measurement. Both measurement modalities showed small differences to rotational imaging (electromagnetic bone tracking [EMT]: 0.72°; goniometer: 1.19°) but a large deviation when compared to three‐dimensional gait analysis (EMT: 8.5°, goniometer: 9.1°). In comparison to the static changes and EMT measurement, the dynamic changes measured during 3‐D‐gait analysis reflected only 66% of the actual derotation performed during surgery. Although electromagnetic tracking allows a precise intraoperative assessment of the derotation during FDO, the amount of intraoperative correction is not reflected in the improvements in three‐dimensional gait analysis. [ABSTRACT FROM AUTHOR]
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- 2022
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15. Development of Knee Function After Hamstring Lengthening as a Part of Multilevel Surgery in Children with Spastic Diplegia: A Long-Term Outcome Study
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Dreher, Thomas, Vegvari, Dóra, Wolf, Sebastian I, Geisbüsch, Andreas, Gantz, Simone, Wenz, Wolfram, and Braatz, Frank
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- 2012
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16. Prevalence and classification of equinus foot in bilateral spastic cerebral palsy.
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Horsch, Axel, Götze, Marco, Geisbüsch, Andreas, Beckmann, Nicholas, Tsitlakidis, Stefanos, Berrsche, Gregor, and Klotz, Matthias
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Background: Equinus is a common deformity in children with bilateral spastic cerebral palsy (BSCP). While dynamic equinus usually is treated by conservative therapy, fixed contractures need surgical correction. To choose the appropriate surgical method, it is important to discriminate between isolated gastrocnemius shortening and combined gastrosoleus complex contracture. Methods: In a retrospective study 938 patients with BSCP were studied. Patients underwent gait analysis and clinical examination. 248 patients (496 limbs) met the inclusion criteria. Data from motion analysis and clinical examination were used to calculate the prevalence and to further classify fixed equinus foot. Results: The prevalence of equinus was 83.3%. During clinical exam 246 (59.6%) limbs showed combined gastrosoleus complex contracture and 167 (40.4%) isolated gastrocnemius contracture. Max. DF at stance and mean DF at initial contact were significantly reduced in combined contracture, while max. ROM was increased (P < 0.05). Conclusions: Corroborating the results of previous studies, in this study there was a high prevalence of fixed equinus in patients with BSCP. The prevalence of equinus correlated with increasing age. As half of the patients with fixed equinus show a different involvement of gastrocnemius and soleus muscle, we recommend to apply Silfverskiöld's test to discriminate between those two types to choose the appropriate surgical therapy. [ABSTRACT FROM AUTHOR]
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- 2019
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17. Supracondylar femoral rotation osteotomy affects frontal hip kinetics in children with bilateral cerebral palsy.
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Thielen, Mirjam, Wolf, Sebastian I, Klotz, Matthias C M, Geisbüsch, Andreas, Putz, Cornelia, Krautwurst, Britta, Dreher, Thomas, and Klotz, Matthias Cm
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CHILDREN with cerebral palsy ,FEMORAL epiphysis ,HIP joint ,OSTEOTOMY ,STANDARD deviations ,CEREBRAL palsy - Abstract
Copyright of Developmental Medicine & Child Neurology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2019
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18. Equinus Correction During Multilevel Surgery in Adults With Cerebral Pals.
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Putz, Cornelia, Mertens, Eva Maria, Wolf, Sebastian I., Geisbüsch, Andreas, Niklasch, Mirjam, Gantz, Simone, Döderlein, Leonhard, Dreher, Thomas, and Klotz, Matthias C.
- Abstract
Background: Equinus foot deformity constitutes a common gait disorder in ambulatory adults with bilateral spastic cerebral palsy (BSCP). The outcome after intramuscular aponeurotic lengthening in the context of single-event multilevel surgery (SEMLS) in adulthood has not been investigated. Methods: We followed a group of 31 ambulatory adults with BSCP and equinus who underwent SEMLS including gastrocnemius-soleus intramuscular aponeurotic recession or Achilles tendon lengthening. All patients were analyzed preoperatively and at least 1 year (mean follow-up period: 1.6 years) postoperatively by clinical examination and 3-dimensional instrumented gait analysis including the Gait Profile Score (GPS). Results: Clinical examination showed no significant improvement of ankle dorsiflexion (P = .5) and an unchanged plantarflexion (P = .7) with knee extended but a significant postoperative reduction of spasticity in the calf muscle (P = .0001) as measured by clinical examination following the modified Ashworth scale. Significant improvement of mean ankle dorsiflexion in stance and swing (P = .0001) was found. The GPS decreased and improved significantly (15.9 ± 4.6 to 11.4 ± 3.1; P = .0001). Persistence of equinus and calcaneal gait indicating under- and overcorrection at follow-up was found in 1 patient (3%), respectively. Conclusion: Intramuscular gastrocnemius-soleus aponeurotic recession is part of multilevel surgery corrected equinus deformity in adults. The increase in muscle length led to significant improvement of kinetic and kinematic parameters during walking without a loss of muscle strength and push-off capacity. The risk of overcorrection after equinus correction in adults with BSCP was found to be relatively low. Level of Evidence: Level IV, retrospective case series. [ABSTRACT FROM AUTHOR]
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- 2018
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19. Electromagnetic bone segment tracking to control femoral derotation osteotomy-A saw bone study.
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Geisbüsch, Andreas, Auer, Christoph, Dickhaus, Hartmut, Niklasch, Mirjam, and Dreher, Thomas
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CHILDREN with cerebral palsy , *GAIT disorders in children , *OSTEOTOMY , *INTRAOPERATIVE care , *PEDIATRIC orthopedics , *PHYSIOLOGY , *THERAPEUTICS - Abstract
ABSTRACT Correction of rotational gait abnormalities is common practice in pediatric orthopaedics such as in children with cerebral palsy. Femoral derotation osteotomy is established as a standard treatment, however, different authors reported substantial variability in outcomes following surgery with patients showing over- or under-correction. Only 60% of the applied correction is observed postoperatively, which strongly suggests intraoperative measurement error or loss of correction during surgery. This study was conducted to verify the impact of error sources in the derotation procedure and assess the utility of a newly developed, instrumented measurement system based on electromagnetic tracking aiming to improve the accuracy of rotational correction. A supracondylar derotation osteotomy was performed in 21 artificial femur sawbones and the amount of derotation was quantified during the procedure by the tracking system and by nine raters using a conventional goniometer. Accuracy of both measurement devices was determined by repeated computer tomography scans. Average derotation measured by the tracking system differed by 0.1° ± 1.6° from the defined reference measurement . In contrast, a high inter-rater variability was found in goniometric measurements (range: 10.8° ± 6.9°, mean interquartile distance: 6.6°). During fixation of the osteosynthesis, the tracking system reliably detected unintentional manipulation of the correction angle with a mean absolute change of 4.0° ± 3.2°. Our findings show that conventional control of femoral derotation is subject to relevant observer bias whereas instrumental tracking yields accuracy better than ±2°. The tracking system is a step towards more reliable and safe implementation of femoral correction, promising substantial improvements of patient safety in the future. © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 35:1106-1112, 2017. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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