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In patients with haemophilia, any oral surgery carries the risk of prolonged and excessive bleeding. Close collaboration between haematologists and oral surgeons is necessary to prevent excessive bleeding. No procedure can be considered minor in a patient with haemophilia because of the serious potential consequences. Successful treatment protocols using systemic treatment, antifibrinolytic agents and local haemostatic measures are described in the current literature.

Deliberate hypotension during anesthesia or hypotensive anesthesia is often used in major maxillofacial surgeries that are at risk of considerable intraoperative bleeding. The outcome of this type of interventions depends on the quality of the surgical field conditions. The level of the blood pressure reduction should be adjusted to the patient’s comorbidities. Careful patient selection and close monitoring with adequate intraoperative volume replacement are mandatory for its safe implementation in surgical cases.

ABSTRACT Basal cell carcinoma (BCC) arises and evolves through intricately mixed, intertwined actions between phenotypic, genetic and environmental factors. Despite being the preponderant type of neoplasia and its frequent location in the accessible and visible region of head and neck, it is commonly considered that a substantial number of BCC cases are diagnosed in the late stages, or even remain undiagnosed at all. Since a proper and timely discovery of all malignancies are key factors in the treatment and life prognostic of patients, a literature survey was made on BCCs to point out current and perspective elements of diagnosis that could be relevant in increasing the success rate of a clear, precise diagnostic. The cumulative use of non-invasive methods based on visual inspection, dermoscopy and other imagistic/computational tools is the first choice in early detection of BCC, while the biopsy followed by histopathological examination are recommended when reasonable uncertainties regarding the type and aggressivity of disease still remain unacknowledged after the initial follow-up.

There are two main methods used for dentin hypersensitivity (DH) treatment: dentinal tubule occlusion and blockage of nerve activity. Dentifrices are the most common vehicles for active ingredients used for DH treatment. The aim of this study was to evaluate the efficacy of three toothpastes on dentinal tubule occlusion, mineral acquisition, and dentin hardness. Forty human dentin disks were submerged in 40% citric acid for 30 s and then exposed to tooth brushing for 2 min twice a day for 14 days using three toothpastes: Dontodent Sensitive (group 1), Dr. Wolff’s Biorepair (group 2), and Sensodyne Repair and Protect (group 3). In the control group (group 4), the samples were brushed with water. All of the samples were evaluated using scanning electron microscopy (SEM), energy-dispersive X-ray (EDX), and Vickers dentin hardness determination. On SEM images, the degree of dentinal tubule occlusion was assessed using a five-grade scale. The mean score values in groups 1–4 were 3.60 ± 0.69, 2.20 ± 0.91, 2.30 ± 1.16, and 5.00 ± 0.00, significantly higher in study groups when compared to the control group (Kruskal Wallis test p < 0.05). EDX evaluation showed significantly higher calcium and phosphorus concentrations in groups 1 and 3 when compared to control group d. The mean values of Vickers dentin hardness numbers in groups 1–4 were 243.03 ± 10.014, 327.38 ± 56.65, 260.29 ± 37.69, and 225.83 ± 29.93, respectively. No statistically significant results were obtained when comparing the hardness mean values in groups (Kruskal-Wallis statistical test, p = 0.372 > 0.05). All three toothpastes tested demonstrated significant occlusion of dentinal tubules. Dontodent Sensitive and Sensodyne Repair and Protect toothpastes enhanced the calcium and phosphorus content of the dentin surface. None of the toothpastes increased dentin hardness as a result of mineral acquisition.

Aim of the study: The aim of this study was to validate and implement the Romanian version of DHEQ-15. Material and methods: A total of 132 questionnaires DHEQ-15 were distributed among senior dental students (6th year of study). The DHEQ-15 consists of 15 items with coded responses on 7-point Likert scales. The form was translated into Romanian using the forward-backward process. The standard descriptive methods were applied to determine the characteristics of the sample. Results: The response rate of the self-administered questionnaire was 87.87%. A total of 74 students (63.8%) declared that had experienced DH in the last month and 58% of them disagreed that this condition had a negative impact on their lives. The average total score recorded was 46.16 ± 19.680. Conclusions: This is the first study that validates the Romanian version of DHEQ-15. The findings of this research indicate that senior dental students do not consider that DH has a negative impact on their quality of life.

The traditional view, that consider the carious disease as an infectious disease where the therapeutic strategy requires the removal of bacteria and affected tissues, is no longer valid today. Alternative therapies involving the control of causative factors (carbohydrate restrictions, biofilm removal) or to rebalance de- and remineralization processes (fluoride and other remineralization strategies or sealing placement) have become the cornerstone of “the tooth decay management”. These new therapies allow “the inactivation / control of the caries process, preservation of dental hard tissues, avoidance of repetitive restorative cycle, and maintenance of the tooth throughout the patient’s life “. Today we have techniques for the selective removal of decayed the carious tissues that maintain a minimal area of soft or firm dentin near to the pulp and create a sealing area on the periphery in which healthy dentin and enamel on the walls and borders of the cavity provide an effective substrate for bio-adhesive restorations.

Aim of the study This review focuses on Computer-Controlled Local Anaesthetic Delivery systems (CCLAD) versus conventional carpule anaesthesia in its efficiency to reduce pain and anxiety. Material and methods For this purpose, we have searched for relevant studies in Science Direct, Thomson ISI – Web of Science, Scopus, PubMed, Google Scholar covering the period up to December 2018. We have included only the studies investigating oral surgery maneuvers that compared clinically CCLAD to conventional techniques. The authors looked mainly for data on pain, anxiety and effectiveness related to anaesthesia. Results The review provides a critical overview of 6 studies (n=325 subjects). Conclusions The review enabled the authors to draw the conclusion that CCLAD results in significantly lower level of pain perception compared to conventional injections, and it is a promising device for helping patients deal with pain perception. The literature needs to be expanded, mostly regarding anxiety and efficiency in oral surgery.

This in vitro study evaluated the effects of dentifrices containing nano-hydroxyapatite (n-HAp) on dentinal tubule occlusion and on mineral deposition. Dentin specimens of ten human teeth were submersed for 30 s in 40% citric acid and then randomly divided into four groups (three study groups and one control group). In the study groups, the dentin samples were exposed to three different n-HAp toothpastes: Karex (Dr. Kurt Wolff GmbH & Co. KG, Bielefeld, Germany), Biorepair Plus Sensitive (Coswell SpA, Bologna, Italy), and Dr. Wolff’s Biorepair (Dr. Kurt Wolff GmbH & Co. KG, Bielefeld, Germany); in the control group no toothpaste was applied. All of the samples were evaluated using scanning electron microscopy (SEM) and energy-dispersive X-ray (EDX) analysis. In the control group all of the samples showed a frank and wide opening of the dentinal tubules, whereas in the study groups different degrees of tubule closure by mineral depositions were observed. Toothpastes containing n-HAp determined a significant occlusion of dentinal tubules and a significant increase of mineral deposition on the dentin surface. All three tested toothpastes showed similar results regarding the degree of dentinal tubule closure. Varying degrees of differences in calcium, phosphate, carbon, and oxygen ion concentrations among the three tested toothpastes were obtained.