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Your search keyword '"Ebner, Florian"' showing total 471 results
Start Over Author "Ebner, Florian" Publication Type Academic Journals
471 results on '"Ebner, Florian"'

1. Skepticism towards advancing VR technology – student acceptance of VR as a teaching and assessment tool in medicine

Author

Walter, Steffen, Speidel, Robert, Hann, Alexander, Leitner, Janine, Jerg-Bretzke, Lucia, Kropp, Peter, Garbe, Jakob, and Ebner, Florian

Subjects
virtual reality, virtual patient, medical training, future, acceptance, Special aspects of education, LC8-6691, Medicine
Abstract

Objective: The high didactic potential of Virtual Reality (VR) contrasts with the point of view of students that the technology only has a relatively low significance for current and future teaching. This discrepancy was studied in a differentiated manner in order to gear the further development and implementation of VR towards the target group.Methods: From January 2020 to July 2020, medical students () were asked to watch ten videos online and rate them on the basis of acceptance indicators (e.g., fun and fairness). Using obstetrics as an example, the videos demonstrated five levels of VR technology functionality (e.g., haptic and adaptive feedback), some of which were visionary, in two use scenarios (teaching and the OSCE). The individual and aggregate indicators were compared with non-parametric testing procedures across application scenarios, functional levels and genders. In addition, correlations between the acceptance and the factors of semester, age, computer affinity, and previous VR experience were analyzed.Results: Across all functional levels, VR was more likely to be accepted in the classroom than in the OSCE. Comparisons across functional levels also revealed that the VR ready to be marketed was significantly more accepted than the visionary functions. This skepticism toward advancing VR technology was most pronounced with regard to the vision of autonomous VR examinations and among female students with a low computer affinity.Conclusion: The results suggest that the students’ reservations are due to a lack of experience with the VR technology. In order for young physicians to become familiar with the technology and to be able to use it competently in the everyday clinical practice in the future, VR should not only be used as a teaching tool but also be part of the curriculum. Practical examinations using VR, on the other hand, are only recommended once the technology has become established in teaching and has been proven to be reliable.

Published
2021
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8. Effects of very early hyperoxemia on neurologic outcome after out-of-hospital cardiac arrest: A secondary analysis of the TTM-2 trial

Author

Sanfilippo, Filippo, Uryga, Agnieszka, Santonocito, Cristina, Jakobsen, Janus Christian, Lilja, Gisela, Friberg, Hans, Wendel-Garcia, Pedro David, Young, Paul J., Eastwood, Glenn, Chew, Michelle S., Unden, Johan, Thomas, Matthew, Grejs, Anders M, Wise, Matt P., Lundin, Andreas, Hollenberg, Jacob, Hammond, Naomi, Saxena, Manoj, Martin, Annborn, Bánszky, Robert, Taccone, Fabio Silvio, Dankiewicz, Josef, Nielsen, Niklas, Ebner, Florian, BeloholaveK, Jan, Hanggi, Matthias, Montagnani, Luca, Patroniti, Nicolo’, and Robba, Chiara

Published
2024
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16. Semen inhibits Zika virus infection of cells and tissues from the anogenital region.

Author

Müller, Janis A, Harms, Mirja, Krüger, Franziska, Groß, Rüdiger, Joas, Simone, Hayn, Manuel, Dietz, Andrea N, Lippold, Sina, von Einem, Jens, Schubert, Axel, Michel, Manuela, Mayer, Benjamin, Cortese, Mirko, Jang, Karen S, Sandi-Monroy, Nathallie, Deniz, Miriam, Ebner, Florian, Vapalahti, Olli, Otto, Markus, Bartenschlager, Ralf, Herbeuval, Jean-Philippe, Schmidt-Chanasit, Jonas, Roan, Nadia R, and Münch, Jan

Subjects
Genitalia, Cell Line, Tumor, Vero Cells, Fibroblasts, Semen, Animals, Cercopithecus aethiops, Humans, Sexually Transmitted Diseases, Viral, RNA, Viral, Viral Load, Inhibitory Concentration 50, Virus Replication, Female, Male, Virus Attachment, Primary Cell Culture, Healthy Volunteers, Extracellular Vesicles, Zika Virus, Zika Virus Infection, Chlorocebus aethiops, Cell Line, Tumor, RNA, Viral, Sexually Transmitted Diseases
Abstract

Zika virus (ZIKV) causes severe birth defects and can be transmitted via sexual intercourse. Semen from ZIKV-infected individuals contains high viral loads and may therefore serve as an important vector for virus transmission. Here we analyze the effect of semen on ZIKV infection of cells and tissues derived from the anogenital region. ZIKV replicates in all analyzed cell lines, primary cells, and endometrial or vaginal tissues. However, in the presence of semen, infection by ZIKV and other flaviviruses is potently inhibited. We show that semen prevents ZIKV attachment to target cells, and that an extracellular vesicle preparation from semen is responsible for this anti-ZIKV activity. Our findings suggest that ZIKV transmission is limited by semen. As such, semen appears to serve as a protector against sexual ZIKV transmission, despite the availability of highly susceptible cells in the anogenital tract and high viral loads in this bodily fluid.

Published
2018

17. Oxygen targets and 6-month outcome after out of hospital cardiac arrest: a pre-planned sub-analysis of the targeted hypothermia versus targeted normothermia after Out-of-Hospital Cardiac Arrest (TTM2) trial

Author

Robba, Chiara, Badenes, Rafael, Battaglini, Denise, Ball, Lorenzo, Sanfilippo, Filippo, Brunetti, Iole, Jakobsen, Janus Christian, Lilja, Gisela, Friberg, Hans, Wendel-Garcia, Pedro David, Young, Paul J., Eastwood, Glenn, Chew, Michelle S., Unden, Johan, Thomas, Matthew, Joannidis, Michael, Nichol, Alistair, Lundin, Andreas, Hollenberg, Jacob, Hammond, Naomi, Saxena, Manoj, Martin, Annborn, Solar, Miroslav, Taccone, Fabio Silvio, Dankiewicz, Josef, Nielsen, Niklas, Grejs, Anders Morten, Ebner, Florian, and Pelosi, Paolo

Published
2022
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25. Feasibility of a large multi-center translational research project for newly diagnosed breast and ovarian cancer patients with affiliated biobank: the BRandO biology and outcome (BiO)-project

Author

De Gregorio, Amelie, Nagel, Gabriele, Möller, Peter, Rempen, Andreas, Schlicht, Erik, Fritz, Steffen, Flock, Felix, Kühn, Thorsten, Thiel, Falk, Felberbaum, Ricardo, Ebner, Florian, De Gregorio, Nikolaus, Friedl, Thomas Wolfram Paul, Wiesmüller, Lisa, Kuhn, Peter, Schmitt, Margit, Janni, Wolfgang, Rothenbacher, Dietrich, and Huober, Jens

Published
2020
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38. The association of partial pressures of oxygen and carbon dioxide with neurological outcome after out-of-hospital cardiac arrest: an explorative International Cardiac Arrest Registry 2.0 study

Author

Ebner, Florian, Riker, Richard R., Haxhija, Zana, Seder, David B., May, Teresa L., Ullén, Susann, Stammet, Pascal, Hirsch, Karen, Forsberg, Sune, Dupont, Allison, Friberg, Hans, McPherson, John A., Søreide, Eldar, Dankiewicz, Josef, Cronberg, Tobias, and Nielsen, Niklas

Published
2020
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43. Type I Interferon Signaling Prevents IL-1β-Driven Lethal Systemic Hyperinflammation during Invasive Bacterial Infection of Soft Tissue

Author

Castiglia, Virginia, Piersigilli, Alessandra, Ebner, Florian, Janos, Marton, Goldmann, Oliver, Damböck, Ursula, Kröger, Andrea, Weiss, Sigfried, Knapp, Sylvia, Jamieson, Amanda M., Kirschning, Carsten, Kalinke, Ulrich, Strobl, Birgit, Müller, Mathias, Stoiber, Dagmar, Lienenklaus, Stefan, and Kovarik, Pavel

Published
2016
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49. Quantitative Anatomical Comparison of Surgical Approaches to Meckel's Cave.

Author

Zanin, Luca, Agosti, Edoardo, Ebner, Florian, de Maria, Lucio, Belotti, Francesco, Buffoli, Barbara, Rezzani, Rita, Hirt, Bernard, Ravanelli, Marco, Ius, Tamara, Zeppieri, Marco, Tatagiba, Marcos Soares, Fontanella, Marco Maria, and Doglietto, Francesco

Subjects
CEREBELLOPONTILE angle, MANDIBULAR nerve, MAXILLARY nerve, MAXILLECTOMY, HEALTH care networks, BRAIN anatomy, SKULL base
Abstract

Background: Meckel's cave is a challenging surgical target due to its deep location and proximity to vital neurovascular structures. Surgeons have developed various microsurgical transcranial approaches (MTAs) to access it, but there is no consensus on the best method. Newer endoscopic approaches have also emerged. This study seeks to quantitatively compare these surgical approaches to Meckel's cave, offering insights into surgical volumes and exposure areas. Methods: Fifteen surgical approaches were performed bilaterally in six specimens, including the pterional approach (PTA), fronto-temporal-orbito-zygomatic approach (FTOZA), subtemporal approach (STA), Kawase approach (KWA), retrosigmoid approach (RSA), retrosigmoid approach with suprameatal extension (RSAS), endoscopic endonasal transpterygoid approach (EETPA), inferolateral transorbital approach (ILTEA) and superior eyelid approach (SEYA). All the MTAs were performed both with 10 mm and 15 mm of brain retraction, to consider different percentages of surface exposure. A dedicated navigation system was used to quantify the surgical working volumes and exposure of different areas of Meckel's cave (ApproachViewer, part of GTx-Eyes II, University Health Network, Toronto, Canada). Microsurgical transcranial approaches were quantified with two different degrees of brain retraction (10 mm and 15 mm). Statistical analysis was performed using a mixed linear model with bootstrap resampling. Results: The RSAS with 15 mm of retraction offered the maximum exposure of the trigeminal stem (TS). If compared to the KWA, the RSA exposed more of the TS (69% vs. 46%; p = 0.01). The EETPA and ILTEA exposed the Gasserian ganglion (GG) mainly in the anteromedial portion, but with a significant 20% gain in exposure provided by the EETPA compared to ILTEA (42% vs. 22%; p = 0.06). The STA with 15 mm of retraction offered the maximum exposure of the GG, with a significant gain in exposure compared to the STA with 10 mm of retraction (50% vs. 35%; p = 0.03). The medial part of the three trigeminal branches was mainly exposed by the EETPA, particularly for the ophthalmic (66%) and maxillary (83%) nerves. The EETPA offered the maximum exposure of the medial part of the mandibular nerve, with a significant gain in exposure compared to the ILTEA (42% vs. 11%; p = 0.01) and the SEY (42% vs. 2%; p = 0.01). The FTOZA offered the maximum exposure of the lateral part of the ophthalmic nerve, with a significant gain of 67% (p = 0.03) and 48% (p = 0.04) in exposure compared to the PTA and STA, respectively. The STA with 15 mm of retraction offered the maximum exposure of the lateral part of the maxillary nerve, with a significant gain in exposure compared to the STA with 10 mm of retraction (58% vs. 45%; p = 0.04). The STA with 15 mm of retraction provided a significant exposure gain of 23% for the lateral part of the mandibular nerve compared to FTOZA with 15 mm of retraction (p = 0.03). Conclusions: The endoscopic approaches, through the endonasal and transorbital routes, can provide adequate exposure of Meckel's cave, especially for its more medial portions, bypassing the impediment of major neurovascular structures and significant brain retraction. As far as the most lateral portion of Meckel's cave, MTA approaches still seem to be the gold standard in obtaining optimal exposure and adequate surgical volumes. [ABSTRACT FROM AUTHOR]

Published
2023
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