90 results on '"Diop, I"'
Search Results
2. Mechanical behavior of coated T91 steel in contact with lead–bismuth liquid alloy at 300 °C
- Author
-
Proriol Serre, I., Diop, I., David, N., Vilasi, M., and Vogt, J.-B.
- Published
- 2011
- Full Text
- View/download PDF
3. Experimental investigations and thermodynamic description of the PbO–Fe 2O 3 system
- Author
-
Diop, I., David, N., Fiorani, J.M., Podor, R., and Vilasi, M.
- Published
- 2010
- Full Text
- View/download PDF
4. Experimental investigations and thermodynamic description of the PbO−Bi 2O 3 system
- Author
-
Diop, I., David, N., Fiorani, J.M., Podor, R., and Vilasi, M.
- Published
- 2009
- Full Text
- View/download PDF
5. Superheater fireside corrosion mechanisms in MSWI plants: Lab-scale study and on-site results.
- Author
-
Brossard, J.M., Diop, I., Chaucherie, X., Nicol, F., Rapin, C., and Vilasi, M.
- Published
- 2011
- Full Text
- View/download PDF
6. Experimental investigations and thermodynamic description of the PbO–Fe2O3 system
- Author
-
Diop, I., David, N., Fiorani, J.M., Podor, R., and Vilasi, M.
- Subjects
- *
METALLIC oxides , *THERMODYNAMICS , *STEEL , *NUCLEAR reactors , *CHEMICAL systems , *SPALLATION (Nuclear physics) , *X-ray diffraction , *PHASE diagrams - Abstract
Abstract: The knowledge of the quinary Pb–Bi–O–Fe–Hg is necessary for understanding the degradation mechanisms of the T91 steel used as structure material in future ADS nuclear reactors. In this device, the steel will be in direct contact with the liquid spallation target (which is constituted by lead or lead-bismuth eutectic) surrounded by a reduced oxygen pressure atmosphere. In the present work, the characterization of the pseudo-binary PbO–Fe2O3 cut has been performed. In order to complete the available data in the literature, some experimental investigations by differential thermal analysis (DTA), isothermal annealing, powder X-ray diffraction analysis (XRD), scanning electron microscopy (SEM) and electron probe microanalysis (EPMA) have been done. These results have allowed proposing a thermodynamic assessment using the Calphad method. [ABSTRACT FROM AUTHOR]
- Published
- 2010
- Full Text
- View/download PDF
7. Experimental investigations and thermodynamic description of the PbO−Bi2O3 system
- Author
-
Diop, I., David, N., Fiorani, J.M., Podor, R., and Vilasi, M.
- Subjects
- *
THERMODYNAMICS , *CHEMICAL systems , *THERMAL analysis , *X-ray diffraction , *SCANNING electron microscopy , *ELECTRON probe microanalysis , *LEAD compounds - Abstract
Abstract: In the present work, the experimental characterization of the pseudo-binary PbO–Bi2O3 cut has been performed by differential thermal analysis (DTA), isothermal annealing, powder X-ray diffraction analysis (XRD), scanning electron microscopy (SEM), and electron probe microanalysis (EPMA). A thermodynamic assessment according to the Calphad method was also performed based on the present results as well as previous experimental data using the ThermoCalc software. [Copyright &y& Elsevier]
- Published
- 2009
- Full Text
- View/download PDF
8. Interactive involvement of brain derived neurotrophic factor, nerve growth factor, and calcitonin gene related peptide in colonic hypersensitivity in the rat.
- Author
-
Delafoy, I., Gelot, A., Ardid, D., Eschalier, A., Bertrand, C., Doherty, A. M., and Diop, I.
- Subjects
NERVE growth factor ,SENSORY neurons ,NEUROTROPHINS ,PEPTIDE hormones ,INTESTINAL diseases ,IMMUNOREGULATION ,RECEPTOR antibodies - Abstract
Background and aims: Neutrophins are involved in somatic and visceral hypersensitivity. The action of nerve growth factor (NGF) on sensory neurones contributes to the development of referred colonic hypersensitivity induced by trinitrobenzene sulfonic acid (TNBS). Based on data on brain derived neurotrophic factor (BDNF) and calcitonin gene related peptide (CGRP) in pain, the aims of the present study were: (1) to investigate the involvement of BDNF and CGRP in this model of referred colonic hypersensitivity, (2) to test the effect of exogenous BDNF and CGRP on the colonic pain threshold, and (3) to investigate the relationship between BDNF, NGF, and CGRP by testing antineurotrophin antibodies or h-CGRP 8-37 (a CGRP antagonist) on bowel hypersensitivity induced by these peptides. Methods: Colonic sensitivity was assessed using a colonic distension procedure. Results: Anti-BDNF antibody and h-CGRP 8-37 reversed the induced decrease in colonic threshold (33.4 (2.1) and 40.3 (4.1) mm Hg, respectively, compared with a vehicle score of approximately 18 mm Hg; p<0.001). BDNF (1–100 ng/rat intraperitoneally) induced a significant dose dependent decrease in colonic reaction threshold in healthy rats. This effect was reversed by an anti-BDNF antibody and an anti-NGF antibody (33.4 (0.6) v 18.7 (0.7) mm Hg (p<0.001), anti-NGF v vehicle). NGF induced colonic hypersensitivity was reversed by h-CGRP 8-37 but not by the anti-BDNF antibody. Finally, antineurotrophin antibody could not reverse CGRP induced colonic hypersensitivity (at a dose of 1 μg/kg intraperitoneally). Conclusion: Systemic BDNF, NGF, and CGRP can induce visceral hypersensitivity alone and interactively. This cascade might be involved in TNBS induced referred colonic hypersensitivity in which each of these peptides is involved. [ABSTRACT FROM AUTHOR]
- Published
- 2006
- Full Text
- View/download PDF
9. Un cas d'instabilité de pente naturelle: Le versant des madeleinespresqu'ile de Dakar (Sénégal): Analyse, cartographie des risques et prévention.
- Author
-
Fall, Mam, Dia, A., Fall, Meis, Lo, P., and Diop, I.
- Abstract
Copyright of Bulletin of Engineering Geology & the Environment is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Published
- 1996
- Full Text
- View/download PDF
10. Atteintes cardiovasculaires des spondylarthropathies : étude de 20 cas Sénégalais
- Author
-
Diallo, S., Diop, I., Ndongo, S., and Diop, T.
- Published
- 2007
- Full Text
- View/download PDF
11. Réalisation d'une certification internationale iso 9001 version 2000 en préhospitalier : expérience de SOS médecin Sénégal
- Author
-
Diop, M.-S., Regnault, K., Diop, Y., Diop, I.-B., Fall, M., Boukoulou, F., and Signaté, B.
- Published
- 2007
- Full Text
- View/download PDF
12. Prise en charge pre hospitaliere de la douleur au Sénégal : expérience de SOS Médecins-Sénégal
- Author
-
Diop, M.-S., Diop, I.-B., Ba Regnault, K., Signaté, B., Diop, Y., Fall, M., and Boukoulou, F.
- Published
- 2007
- Full Text
- View/download PDF
13. Die Reformdiskussion in der senegalesischen Sprachplanungs-politik
- Author
-
Diop, Ibrahima
- Subjects
education reform ,language jacobinism ,centralisation ,pluralisation ,language culture and language of culture ,Philology. Linguistics ,P1-1091 ,African languages and literature ,PL8000-8844 - Abstract
The reform discussion in Senegalese language planning indicates a review of the situation, which cannot be done without due attention to previous debates regarding the significance of African languages in the postcolonial culture and educational politics.
- Published
- 2009
- Full Text
- View/download PDF
14. QUARITE (quality of care, risk management and technology in obstetrics): a cluster-randomized trial of a multifaceted intervention to improve emergency obstetric care in Senegal and Mali.
- Author
-
Dumont A, Fournier P, Fraser W, Haddad S, Traore M, Diop I, Gueye M, Gaye A, Couturier F, Pasquier JC, Beaudoin F, Lalonde A, Hatem M, Abrahamowicz M, Dumont, Alexandre, Fournier, Pierre, Fraser, William, Haddad, Slim, Traore, Mamadou, and Diop, Idrissa
- Abstract
Background: Maternal and perinatal mortality are major problems for which progress in sub-Saharan Africa has been inadequate, even though childbirth services are available, even in the poorest countries. Reducing them is the aim of two of the main Millennium Development Goals. Many initiatives have been undertaken to remedy this situation, such as the Advances in Labour and Risk Management (ALARM) International Program, whose purpose is to improve the quality of obstetric services in low-income countries. However, few interventions have been evaluated, in this context, using rigorous methods for analyzing effectiveness in terms of health outcomes. The objective of this trial is to evaluate the effectiveness of the ALARM International Program (AIP) in reducing maternal mortality in referral hospitals in Senegal and Mali. Secondary goals include evaluation of the relationships between effectiveness and resource availability, service organization, medical practices, and satisfaction among health personnel.Methods/design: This is an international, multi-centre, controlled cluster-randomized trial of a complex intervention. The intervention is based on the concept of evidence-based practice and on a combination of two approaches aimed at improving the performance of health personnel: 1) Educational outreach visits; and 2) the implementation of facility-based maternal death reviews. The unit of intervention is the public health facility equipped with a functional operating room. On the basis of consent provided by hospital authorities, 46 centres out of 49 eligible were selected in Mali and Senegal. Using randomization stratified by country and by level of care, 23 centres will be allocated to the intervention group and 23 to the control group. The intervention will last two years. It will be preceded by a pre-intervention one-year period for baseline data collection. A continuous clinical data collection system has been set up in all participating centres. This, along with the inventory of resources and the satisfaction surveys administered to the health personnel, will allow us to measure results before, during, and after the intervention. The overall rate of maternal mortality measured in hospitals during the post-intervention period (Year 4) is the primary outcome. The evaluation will also include cost-effectiveness. [ABSTRACT FROM AUTHOR]- Published
- 2009
- Full Text
- View/download PDF
15. Serological survey in a university community after the fourth wave of COVID-19 in Senegal.
- Author
-
Thiam F, Diouara AAM, Ndiaye CSCA, Diouf I, Kebe K, Senghor A, Djoumoi D, Mbaye MN, Diop I, Sane S, Coundoul S, Tene SD, Diop M, Dieng AL, Ndiaye M, Sall SM, Diouf M, and Nguer CM
- Subjects
- Humans, Male, Female, Senegal epidemiology, Adult, Middle Aged, Adolescent, Seroepidemiologic Studies, Young Adult, Cross-Sectional Studies, Universities, COVID-19 epidemiology, COVID-19 immunology, COVID-19 blood, Antibodies, Viral blood, Antibodies, Viral immunology, Immunoglobulin M blood, Immunoglobulin G blood, SARS-CoV-2 immunology, SARS-CoV-2 isolation & purification
- Abstract
A cross-sectional survey was conducted at Polytechnic High School (PHS) to assess the spread of COVID-19 infection among students and staff. A random cluster sampling was conducted between May 19 and August 18, 2022, after the fourth wave of COVID-19 in Senegal. IgM and IgG SARS-CoV-2 antibodies were screened using WANTAI SARS-CoV-2 ELISA assays. Seroprevalence and descriptive statistics were calculated, and associations between seropositivity and different factors were determined using logistic regression. A total of 637 participants were recruited and the median age was 21 years [18-63]. 62.0% of the participants were female, and 36.89% were male, with a male-to-female ratio = 0.59. The overall IgG and IgM seroprevalence were 92% and 6.91% respectively. Among those who tested positive for IgM, 6.75% were also positive for IgG, and 0.15% were negative for IgG. Interestingly, 6.90% of participants tested negative for both IgM and IgG. We found a higher IgM seroprevalence in men than women (9.4% vs. 5.6%) and a lower IgM seroprevalence in (18-25) age group compared to (55-65) years. We revealed a significant difference according to IgG seroprevalence among participants who declared fatigue symptoms [92.06% (95% CI: 89.96-94.16)] compared to those who did not [80.39% (95% CI: 77.31-83.47)], p = 0.0027. IgM seropositivity was found to be associated with Body Mass Index (BMI) categories (O.R. 0.238, p = 0.043), ethnic group (O.R. 0.723, p = 0.046), and marital status (O.R. 2.399, p = 0.021). Additionally, IgG seropositivity was linked to vaccination status (O.R. 4.741, p < 0.001). Our study found that most students and staff at PHS were exposed to SARS-CoV-2, confirming the virus's circulation at the time of the survey. We also identified differences in individual susceptibility that need further clarification. Our results highlight the importance of seroepidemiological surveys to assess the true impact of the COVID-19 pandemic in a community and to monitor variations in antibody response., Competing Interests: The authors have declared that no competing interests exist., (Copyright: © 2024 THIAM et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.)
- Published
- 2024
- Full Text
- View/download PDF
16. Hepatitis E Virus Seroprevalence and Associated Risk Factors in Pregnant Women Attending Antenatal Consultations in Senegal.
- Author
-
Diouara AAM, Lo S, Nguer CM, Senghor A, Diop Ndiaye H, Manga NM, Danfakha F, Diallo S, Faye Dieme ME, Thiam O, Biaye B, Manga NMP, Thiam F, Sarr H, Lo G, Ndour M, Manga SP, Diaby N, Dieng M, Diop I, Dieye Y, Toure Kane C, Peeters M, and Ayouba A
- Subjects
- Female, Hepatitis Antibodies, Humans, Immunoglobulin G, Immunoglobulin M, Pregnancy, Pregnant Women, Referral and Consultation, Risk Factors, Senegal epidemiology, Seroepidemiologic Studies, Hepatitis E, Hepatitis E virus
- Abstract
In West Africa, research on the hepatitis E virus (HEV) is barely covered, despite the recorded outbreaks. The low level of access to safe water and adequate sanitation is still one of the main factors of HEV spread in developing countries. HEV infection induces acute or sub-clinical liver diseases with a mortality rate ranging from 0.5 to 4%. The mortality rate is more alarming (15 to 25%) among pregnant women, especially in the last trimester of pregnancy. Herein, we conducted a multicentric socio-demographic and seroepidemiological survey of HEV in Senegal among pregnant women. A consecutive and non-redundant recruitment of participants was carried out over the period of 5 months, from March to July 2021. A total of 1227 consenting participants attending antenatal clinics responded to a standard questionnaire. Plasma samples were collected and tested for anti-HEV IgM and IgG by using the WANTAI HEV-IgM and IgG ELISA assay. The overall HEV seroprevalence was 7.8% (n = 96), with 0.5% (n = 6) and 7.4% (n = 91) for HEV IgM and HEV IgG, respectively. One of the participant samples was IgM/IgG-positive, while four were declared indeterminate to anti-HEV IgM as per the manufacturer’s instructions. From one locality to another, the seroprevalence of HEV antibodies varied from 0 to 1% for HEV IgM and from 1.5 to 10.5% for HEV IgG. The data also showed that seroprevalence varied significantly by marital status (p < 0.0001), by the regularity of income (p = 0.0043), and by access to sanitation services (p = 0.0006). These data could serve as a basis to setup national prevention strategies focused on socio-cultural, environmental, and behavioral aspects for a better management of HEV infection in Senegal.
- Published
- 2022
- Full Text
- View/download PDF
17. [Practical management of long Covid disease in outpatients: illustration by clinical cases].
- Author
-
Marone Diop I, Kokkinakis I, Wenker Dabiri C, De Vallière S, Cornuz J, and Favrat B
- Subjects
- Humans, Pandemics, SARS-CoV-2, Post-Acute COVID-19 Syndrome, COVID-19 complications, Outpatients
- Abstract
The SARS-CoV-2 pandemic has caused an unprecedented global public health crisis. The term long Covid is used to describe diverse and heterogeneous symptoms that persist more than 4 weeks after infection with an estimated incidence of 10-40%, which varies between studies. The principal characteristics of long Covid are fluctuating symptoms of prolonged duration affecting multiple organs, such as fatigue, dyspnea, cough, anosmia, dysgeusia, chest pain, palpitations, headache, myalgia, cognitive and gastrointestinal disorders. Contributing factors, possible pathophysiological explanations and international recommendations can help in the management of the disease in the outpatient setting. Biopsychosocial and multidisciplinary management in primary care medicine is essential., Competing Interests: Les auteurs n’ont déclaré aucun conflit d’intérêts en relation avec cet article.
- Published
- 2021
18. Antihypertensive strategies and hypertension control in Sub-Saharan Africa.
- Author
-
Cavagna P, Stéphane Ikama M, Euloge Kramoh K, Laurent Takombe J, Bara Diop I, Ali Toure I, Balde DM, Dzudie A, Ferreira B, Houenassi MD, Hounkponou M, Kane A, Kimbally-Kaki SG, Kingue S, Kouam Kouam C, Limbole E, Mfeukeu Kuate L, Bruno Mipinda J, N'guetta R, Nhavoto C, Marie Damorou J, Sidy Ali A, Gaye B, Tajeu GS, Macquart de Terline D, Cécile Perier M, Azizi M, Jouven X, and Antignac M
- Subjects
- Africa South of the Sahara epidemiology, Humans, Risk Factors, Antihypertensive Agents therapeutic use, Hypertension diagnosis, Hypertension drug therapy, Hypertension epidemiology
- Published
- 2021
- Full Text
- View/download PDF
19. Poor adherence to medication and salt restriction as a barrier to reaching blood pressure control in patients with hypertension: Cross-sectional study from 12 sub-Saharan countries.
- Author
-
Macquart de Terline D, Kramoh KE, Bara Diop I, Nhavoto C, Balde DM, Ferreira B, Houenassi MD, Hounsou D, Ikama MS, Kane A, Kimbally-Kaki SG, Kingue S, Koffi F, Kouam Kouam C, Limbole E, Mfeukeu Kuate L, Mipinda JB, N'goran Y, Sesso Z, Sidi Aly A, Toure IA, Plouin PF, Azizi M, Perier MC, Narayanan K, Empana JP, Jouven X, and Antignac M
- Subjects
- Africa South of the Sahara epidemiology, Aged, Black People, Cross-Sectional Studies, Female, Health Care Surveys, Health Knowledge, Attitudes, Practice ethnology, Humans, Hypertension diagnosis, Hypertension ethnology, Hypertension physiopathology, Male, Middle Aged, Risk Factors, Treatment Outcome, Antihypertensive Agents therapeutic use, Blood Pressure drug effects, Diet, Sodium-Restricted ethnology, Hypertension therapy, Medication Adherence ethnology, Risk Reduction Behavior
- Abstract
Background: Sub-Saharan Africa is experiencing a rising burden of hypertension. Antihypertensive medications and diet are the cornerstone of effective hypertension control., Aims: To assess adherence to medication and salt restriction in 12 sub-Saharan countries, and to study the relationship between adherence and blood pressure control in patients with hypertension., Methods: We conducted a cross-sectional survey in urban clinics in twelve sub-Saharan countries. Data were collected on demographics, treatment and adequacy of blood pressure control in patients with hypertension attending the clinics. Adherence was assessed by questionnaires completed by the patients. Hypertension grades were defined according to European Society of Cardiology guidelines. Association between adherence and blood pressure control was investigated using multilevel logistic regression analysis, adjusting for age, sex and country., Results: Among the 2198 patients, 77.4% had uncontrolled blood pressure, 34.0% were poorly adherent to salt restriction, 64.4% were poorly adherent to medication and 24.6% were poorly adherent to both. Poor adherence to salt restriction (odds ratio [OR] 1.33, 95% confidence interval [CI] 1.03-1.72), medication (OR 1.56, 95% CI 1.25-1.93) or both (OR 1.91 1.39-2.66) was related to uncontrolled blood pressure. Moreover, poor adherence to both medication and salt restriction was related to a 1.52-fold (95% CI 1.04-2.22), 1.8-fold (95% CI 1.22-2.65) and 3.08-fold (95% CI 2.02-4.69) increased likelihood of hypertension grade 1, 2 and 3, respectively., Conclusions: High levels of poor adherence to salt restriction and medication were noted in this urban sub-Saharan study; both were significantly associated with uncontrolled blood pressure, representing major opportunities for intervention to improve hypertension control in sub-Saharan Africa., (Copyright © 2020 Elsevier Masson SAS. All rights reserved.)
- Published
- 2020
- Full Text
- View/download PDF
20. Over the counter: The potential for easing pharmacy provision of family planning in urban Senegal.
- Author
-
Peterson J, Brunie A, Diop I, Diop S, Stanback J, and Chin-Quee DS
- Abstract
Background: This research assessed the potential for expanding access to family planning through private sector pharmacies in Senegal, by examining the quality of the services provided through private sector pharmacies, and pharmacy staff and client interest in private sector pharmacy-based family planning services. Methods: This was a cross-sectional, descriptive study conducted in eight urban districts in and around Dakar and two urban districts outside of Dakar employing an audit of 225 pharmacies, a survey with 486 private sector pharmacy staff and a survey with 3,567 women exiting private sector pharmacies. Results: Most (54%) pharmacies reported offering method-specific counseling to clients. Family planning commodities were available in all pharmacies, and 72% had a private space available to offer counseling. Three quarters (76%) did not have any counseling materials available. 49% of pharmacists and 47% of assistant pharmacists reported receiving training on family planning during their professional studies. Half had received counseling training. Few pharmacists met pre-determined criteria to be considered highly knowledgeable of the oral contraceptive pill (OCP) and injectable contraceptive provision (0.6% and 1.1%). Overall, 60% of women surveyed were current family planning users and 11% procured their method through a private sector pharmacy. Among non-users of family planning, and current users who did not obtain their method through a pharmacy, 47% said they would be interested in procuring a method through a private sector pharmacy. Conclusions: There is both actual and latent demand for accessing family planning through Senegal's urban, private sector pharmacies. With proper training, pharmacy staff could better provide effective counseling and provision of OCPs and injectables, and lifting the requirement for a prescription could help support gains in contraceptive prevalence., Competing Interests: No competing interests were disclosed., (Copyright: © 2019 Peterson J et al.)
- Published
- 2019
- Full Text
- View/download PDF
21. Over the counter: The potential for easing pharmacy provision of family planning in Senegal.
- Author
-
Peterson J, Brunie A, Diop I, Diop S, Stanback J, and Chin-Quee DS
- Abstract
Background: This research assessed the potential for expanding access to family planning through private sector pharmacies in Senegal, by examining the quality of the services provided through private sector pharmacies, and pharmacy staff and client interest in private sector pharmacy-based family planning services. Methods: This was a cross-sectional, descriptive study conducted in eight urban districts in and around Dakar and two urban districts outside of Dakar employing an audit of 225 pharmacies, a survey with 486 private sector pharmacy staff and a survey with 3,567 women exiting private sector pharmacies. Results: Most (54%) pharmacies reported offering method-specific counseling to clients. Family planning commodities were available in all pharmacies, and 72% had a private space available to offer counseling. Three quarters (76%) did not have any counseling materials available. 49% of pharmacists and 47% of assistant pharmacists reported receiving training on family planning during their professional studies. Half had received counseling training. Few pharmacists met pre-determined criteria to be considered highly knowledgeable of the oral contraceptive pill (OCP) and injectable contraceptive provision (0.6% and 1.1%). Overall, 60% of women surveyed were current family planning users and 11% procured their method through a private sector pharmacy. Among non-users of family planning, and current users who did not obtain their method through a pharmacy, 47% said they would be interested in procuring a method through a private sector pharmacy. Conclusions: Senegal's urban, private sector pharmacies are well-positioned to meet the increasing desire for modern contraception. With proper training, pharmacy staff could better provide effective counseling and provision of OCPs and injectables, and lifting the requirement for a prescription could help support gains in contraceptive prevalence., Competing Interests: No competing interests were disclosed.
- Published
- 2018
- Full Text
- View/download PDF
22. Intrapericardial rupture of a mitral subannular aneurysm: A case report and review of the literature.
- Author
-
Diop IB, Leye M, Diallo AD, Sarr EH, Manga SJ, Diene LL, and Jobe M
- Subjects
- Adult, Fatal Outcome, Heart Aneurysm etiology, Humans, Male, Rupture, Spontaneous, Senegal, Heart Aneurysm complications, Heart Valve Diseases complications, Mitral Valve, Pericardium
- Abstract
Mitral subannular aneurysm is a rare heart disease that can have many different forms of clinical presentations. It was first described in young men of African descent and was later reported in other geographical areas of the world. The etiopathogenesis as per data from the literature can be congenital, acquired or idiopathic. We report the case of a 19-year-old male in whom we made the diagnosis of mitral subannular aneurysm. The evolution was fatal following a rupture of the aneurysm into the pericardium. Through this case report, we stress the importance of echocardiography in the diagnosis of this condition. In resource-limited countries, the prognosis is unfortunately often unfavorable especially the ruptured forms. Therefore, a high degree of suspicion is needed to make a prompt diagnosis and timely surgical intervention., (Copyright © 2015 Elsevier Masson SAS. All rights reserved.)
- Published
- 2016
- Full Text
- View/download PDF
23. Developing a tool to measure satisfaction among health professionals in sub-Saharan Africa.
- Author
-
Faye A, Fournier P, Diop I, Philibert A, Morestin F, and Dumont A
- Abstract
Background: In sub-Saharan Africa, lack of motivation and job dissatisfaction have been cited as causes of poor healthcare quality and outcomes. Measurement of health workers' satisfaction adapted to sub-Saharan African working conditions and cultures is a challenge. The objective of this study was to develop a valid and reliable instrument to measure satisfaction among health professionals in the sub-Saharan African context., Methods: A survey was conducted in Senegal and Mali in 2011 among 962 care providers (doctors, midwives, nurses and technicians) practicing in 46 hospitals (capital, regional and district). The participation rate was very high: 97% (937/962). After exploratory factor analysis (EFA), construct validity was assessed through confirmatory factor analysis (CFA). The discriminant validity of our subscales was evaluated by comparing the average variance extracted (AVE) for each of the constructs with the squared interconstruct correlation (SIC), and finally for criterion validity, each subscale was tested with two hypotheses. Two dimensions of reliability were assessed: internal consistency with Cronbach's alpha subscales and stability over time using a test-retest process., Results: Eight dimensions of satisfaction encompassing 24 items were identified and validated using a process that combined psychometric analyses and expert opinions: continuing education, salary and benefits, management style, tasks, work environment, workload, moral satisfaction and job stability. All eight dimensions demonstrated significant discriminant validity. The final model showed good performance, with a root mean square error of approximation (RMSEA) of 0.0508 (90% CI: 0.0448 to 0.0569) and a comparative fit index (CFI) of 0.9415. The concurrent criterion validity of the eight dimensions was good. Reliability was assessed based on internal consistency, which was good for all dimensions but one (moral satisfaction < 0.70). Test-retest showed satisfactory temporal stability (intra class coefficient range: 0.60 to 0.91)., Conclusions: Job satisfaction is a complex construct; this study provides a multidimensional instrument whose content, construct and criterion validities were verified to ensure its suitability for the sub-Saharan African context. When using these subscales in further studies, the variability of the reliability of the subscales should be taken in to account for calculating the sample sizes. The instrument will be useful in evaluative studies which will help guide interventions aimed at improving both the quality of care and its effectiveness.
- Published
- 2013
- Full Text
- View/download PDF
24. [Using routine information system data to assess maternal and perinatal care services in Mali and Senegal (QUARITE trial)].
- Author
-
Dumont A, Gueye M, Sow A, Diop I, Konate MK, Dambé P, Abrahamowicz M, and Fournier P
- Subjects
- Adolescent, Adult, Developing Countries, Female, Health Information Systems statistics & numerical data, Humans, Mali, Perinatal Care statistics & numerical data, Pregnancy, Senegal, Health Information Systems standards, Maternal Welfare statistics & numerical data, Perinatal Care standards
- Abstract
Background: In sub-Saharan Africa, problems of access to relevant and high-quality facility-based statistics hinder the assessment of safe motherhood programs. The objective of this study was to assess the quality of data collected in referral hospitals in Mali and Senegal after the routine information system (RIS) was strengthened., Methods: This was a multicenter observational study conducted during the pre-intervention period of a randomized controlled trial (trial QUARITE). The RIS was strengthened based on technical, organizational and behavioral factors. We included all women who gave birth in the 46 referral hospitals from October 1, 2007 to October 30, 2008. The completeness, completion and accuracy rates were monitored every 3 months in each hospital. The cost of investment needed to strengthen the existing RIS was also determined., Results: The mean completeness rate ranged from 94 to 97% depending on the study period. The completion and accuracy rates increased during the study period from 72% and 79% to 87% and 93%, respectively (significant differences). The average investment per hospital was less than 1% of state subsidies for public hospitals., Conclusion: Strengthening the existing information system has set up an economically and technologically appropriate system for monitoring maternal and perinatal health in Senegal and Mali. We encourage policy makers and researchers from countries with limited resources to invest in RIS to improve and monitor the performance of health systems., (Copyright © 2012 Elsevier Masson SAS. All rights reserved.)
- Published
- 2012
- Full Text
- View/download PDF
25. [Role of thrombolysis in massive pulmonary embolism].
- Author
-
Ndiaye MB, Diao M, Kane AD, Mbaye A, Mohamed A, Yameogo NV, Bodian M, Dia MM, Diop IB, Sarr M, Kane A, and Ba SA
- Subjects
- Adolescent, Adult, Aged, Echocardiography, Electrocardiography, Female, Humans, Male, Middle Aged, Vitamin K antagonists & inhibitors, Young Adult, Anticoagulants therapeutic use, Fibrinolytic Agents therapeutic use, Pulmonary Embolism drug therapy
- Abstract
Aims: Massive pulmonary embolism is a life threatening pathology with a high mortality over 20%. Thrombolysis is one of therapy ways that leads to a lower rate of death. The aim of the study is to show interest, limits and complications of thrombolytic therapy in massive pulmonary embolism., Patients and Methods: This descriptive study presents 8 cases of pulmonary embolism admitted to the Cardiology Division of Grand-Yoff from March 2003 to March 2006. All cases confirmed by Tomodensitometry (TDM) with massive pulmonary embolism were included in this study., Results: We used thrombolytic only in 8 cases of massive pulmonary embolism about 32. In-hospital prevalence was 25%. The average age was 49.8 ± 19.1 (from 15 to 72) and sex-ratio 0.33. Seven patients had a moderate clinical probability Well's score and one of them 1 had a high clinical probability. The clinical signs were: cardio-vascular collapse (7 cases), syncope (1) and cardio-vascular arrest. The electrocardiogram showed a sub-epicardial ischemia (4 cases), a right bundle branch block and a Mac Ginn White's sign. Two patients had a right-basal opacification at the chest X ray. The echocardiography found 5 cases of right ventricular dilatation, 1 case of paradoxal septum, 1 case of multiple thrombi in the right ventricule. The TDM confirmed diagnosis with 3 cases of bilateral pulmonary embolism, 1 case of pulmonary aneurysm. The treatment used thrombolytic : 1,500,000 IU of streptokinase, sympathomimetic drugs, anticoagulation with heparins and vitamin K antagonists.
- Published
- 2011
26. [Evolution and thromboembolic complications of the idiopathic peripartal cardiomyopathy at Dakar University Hospital: forward-looking study about 33 cases].
- Author
-
Kane A, Mbaye M, Ndiaye MB, Diao M, Moreira PM, Mboup C, Diop IB, Sarr M, Kane A, Moreau JC, and Ba SA
- Subjects
- Adult, Anticoagulants therapeutic use, Atrial Fibrillation diagnostic imaging, Atrial Fibrillation epidemiology, Brain Ischemia diagnostic imaging, Brain Ischemia epidemiology, Cardiomyopathy, Dilated diagnostic imaging, Cardiomyopathy, Dilated drug therapy, Female, Heart Failure diagnostic imaging, Heart Failure epidemiology, Hospitals, University, Humans, Longitudinal Studies, Pilot Projects, Pregnancy, Prevalence, Prospective Studies, Senegal epidemiology, Tachycardia diagnostic imaging, Tachycardia epidemiology, Thromboembolism diagnostic imaging, Ventricular Dysfunction, Left diagnostic imaging, Ventricular Dysfunction, Left epidemiology, Cardiomyopathy, Dilated complications, Echocardiography, Transesophageal, Peripartum Period, Thromboembolism epidemiology, Thromboembolism etiology
- Abstract
Unlabelled: The aims of this work are to study the nursery futures during idiopathic myocardiopathy of peripartum (IMPP), to measure the prevalence of thromboses and spontaneous contrast during the IMPP and to determine their evolution., Methodology: It is about a longitudinal exploratory study carried out with the Aristide-Le-Dantec teaching hospital of Dakar, beginning January 2001 to November 2004, having included 33 patients., Results: The average age of the patients was 26 years; the average pregnancy was of 3.39 gestures. The signs of cardiac insufficiency were constant and four patients (12%) had presented an ischemic cerebral vascular accident. We had raised an auricular case of fibrillation and tachycardia atrial multifocal. The transthoracic echography (ETT) noted an aspect of hypokinetic myocardiopathy dilated with deterioration of the systolic function of the left ventricle, a thrombus in ten patients (30.3%) and a spontaneous contrast in two cases (6%). The transoesophageal echocardiography (ETO) was superposable with the ETT with regard to dimensions of the cardiac cavities and the presence of thrombus but its sensitivity was higher (100% against 66%) with regard to the detection of contrasts spontaneous. All the patients had the treatment of a congestive heart failure associated to an anticoagulant treatment. The evolution was marked by an improvement of the heart failure. The thrombus and spontaneous contrast had disappeared in all the patients. The absence of anaemia and the presence of spontaneous contrast (p=0.003) were correlated with the presence of thrombosis (p=0.05)., Conclusion: The idiopathic myocardiopathy of the peripartum is a relatively frequent affection in zone Soudano-Sahelian. Occurrence of thromboses is frequent at the time of this affection. Our study confirms the superiority of the echocardiography transoesophageal in the detection of intracardiac spontaneous contrast. The evolution can be favourable subject to a rigorous care and a regular surveillance., (Copyright © 2010 Elsevier Masson SAS. All rights reserved.)
- Published
- 2010
- Full Text
- View/download PDF
27. [Systemic vasculitis: study of 27 cases in Senegal].
- Author
-
Ndongo S, Diallo S, Tiendrebeogo J, Diop IB, Tall A, Pouye A, Ka MM, and Diop TM
- Subjects
- Adult, Aged, Anticoagulants therapeutic use, Arthritis, Rheumatoid diagnosis, Arthritis, Rheumatoid drug therapy, Drug Therapy, Combination, Female, Giant Cell Arteritis diagnosis, Giant Cell Arteritis drug therapy, Glucocorticoids therapeutic use, Granulomatosis with Polyangiitis diagnosis, Granulomatosis with Polyangiitis drug therapy, Humans, Immunosuppressive Agents therapeutic use, Male, Middle Aged, Mixed Connective Tissue Disease diagnosis, Mixed Connective Tissue Disease drug therapy, Polyarteritis Nodosa diagnosis, Polyarteritis Nodosa drug therapy, Polymyositis diagnosis, Polymyositis drug therapy, Retrospective Studies, Senegal, Sjogren's Syndrome diagnosis, Sjogren's Syndrome drug therapy, Systemic Vasculitis etiology, Systemic Vasculitis surgery, Takayasu Arteritis diagnosis, Takayasu Arteritis drug therapy, Thromboangiitis Obliterans diagnosis, Thromboangiitis Obliterans drug therapy, Treatment Outcome, Systemic Vasculitis diagnosis, Systemic Vasculitis drug therapy
- Abstract
Studies on vasculitis in black Africa are rare. The purpose of this report is to describe a retrospective study of systemic vasculitis managed in the internal medicine, ORL and cardiolology departments of the Aristide le Dantec University Hospital in Dakar, Senegal from 1995 to 2007. A series of 27 cases involving 7 men and 20 women with a mean age of 49 years was compiled. Primary vasculitis included Horton disease in 3 cases, Wegener disease in 2, Takayasu disease in 1, and Buerger disease in 1. Secondary vasculitis included mixed cryoglobulinemia with Gougerot Sjögren syndrome in 7 cases, primary Goujeröt syndrome in 4, rheumatoid arthritis in 3, nodosa periarteritis with hepatitis B in 2, SHARP syndrome in 1, and polymyositis in 1. The remaining two cases involved abdominal periaortitis including one associated with retrosperitoneal fibrosis and tuberculosis and the other with spondylarthropathy. Corticotherapy in combination with anticoagulants, immunosuppressive therapy, and surgery, when necessary, allowed effective management in 24 cases. The findings of this study show that systemic vasculitis can have numerous etiologies and indicate that secondary forms are the most common. Appropriate care modalities are needed to prevent severe outcome in Senegalese hospitals.
- Published
- 2010
28. [Screening for HIV, syphilis, Chlamydia trachomatis and Neisseria gonorrhoreae during a combined survey conducted in Malicouna, a Senegalese rural area].
- Author
-
Gueye Ndiaye A, Faye CM, Ndiaye I, Fall K, Gueye Gaye A, Diop IL, and Mboup S
- Subjects
- Chlamydia Infections diagnosis, Female, Gonorrhea diagnosis, HIV Infections diagnosis, HIV Seroprevalence, Health Knowledge, Attitudes, Practice, Health Surveys, Humans, Male, Risk-Taking, Rural Population statistics & numerical data, Senegal epidemiology, Seroepidemiologic Studies, Sex Work, Sexual Behavior statistics & numerical data, Syphilis diagnosis, Travel, Chlamydia Infections epidemiology, Chlamydia trachomatis, Gonorrhea epidemiology, HIV Infections epidemiology, Mass Screening, Syphilis epidemiology
- Abstract
To implement a second-generation HIV surveillance, through a prevention programme of HIV and sexually transmitted infections (STIs), Senegal conducted a combined survey from 2003 September 2 to October 5 in Malicounda located in the region of Thiès in the center of Senegal. The objectives of this study were to collect data on sexual behaviours and prevalence of HIV gonorrhoea, Chlamydia infections and syphilis in the community. After obtaining their informed consent, 679 people were interviewed among whom 617 accepted blood sampling and 619 accepted urine sampling, that is to say an acceptance rate of 90% and 91% respectively. Women reported having fewer sexual risk behaviours than men. However, when having sexual risk behaviour men only reported using condoms. Overall, the prevalence of HIV as well as the prevalence of STI are low: 0.5% for HIV, 0.9% for syphilis, 0.3% for Chlamydia trachomatis and 0.2% for Neisseria gonorrhoea. In this study, the small numbers of cases of infection identified did not allow to analyse the influence of sexual behaviour at risk on the occurrence of these infections.
- Published
- 2009
29. [Mitral valve repair for rheumatic valve disease in children in Senegal: a review of 100 cases].
- Author
-
Ciss AG, Diarra O, Dieng PA, N'diaye A, Ba PS, Touré A, Diatta S, Beye SA, Kane O, Diop IB, and N'diaye M
- Subjects
- Adolescent, Child, Humans, Mitral Valve Insufficiency epidemiology, Mitral Valve Insufficiency surgery, Mitral Valve Prolapse surgery, Postoperative Complications epidemiology, Rheumatic Heart Disease mortality, Treatment Outcome, Heart Valve Diseases surgery, Mitral Valve surgery, Rheumatic Heart Disease surgery
- Abstract
Mitral valve repair is a better therapeutic alternative than valve replacement for rheumatic valve disease in children. Repair procedures are especially well suited to developing countries where heart prostheses and life-long anti-coagulation therapy are largely unaffordable. The purpose of this study was to evaluate medium-term outcome of mitral valve repair in children in Senegal. A retrospective review was conducted in a cohort of 100 patients who underwent mitral valve repair for rheumatic mitral lesions over the 8-year period from 1999 to 2007. Mean age was 12 +/- 5 years (range, 7 to 17 years). The most common symptom of valve disease was dysypnea (stage IV in 26 cases and stage III in 74). Valve lesions were complex with anterior leaflet prolapse in 62 cases, posterior leaflet restriction in 35, commissural fusion in 30, and fusion of chordaes in 54. Repair procedures consisted of transfer and shortening of chordaes in 73 cases in association with commissurotomy in 22 cases and cleft closure in 17. Ring annuloplasty was performed in 84 patients. Hospital mortality was 2%. Postoperative morbidity was characterized by residual mitral regurgitation in four cases. Mean follow-up was 5 years. No late deaths were observed. Outcome was satisfactory in 84 patients with low-grade mitral regurgitation (grade I-II). Reduction of left ventricle diameter was statistically significant during systole and diastole, i.e., from 29.5 +/- 6.2 mm to 33.1 +/- 5.3 mm (p<0.05) and from 47.1 +/- 8.6 mm to 50.5 +/- 9.4 mm (p<0.05) respectively. Improvement in cardiac function was not significant, i.e., from 63.3 +/- 4.8% to 62 +/- 6.4% (p = 0.99). Mitral valve repair was successful in stabilizing myocardial function and remodeling the left ventricle. Outcome is dependent on careful patient selection and evaluation of lesions. Middle-term outcome is encouraging.
- Published
- 2009
30. [Development of Ethylcellulose/Eudragit matrix for controlled and continuous release of insulin].
- Author
-
Mbaye G, Ndiaye A, Diouf LA, Diallo AS, Diedhiou A, Sene M, Mbodj M, Thioune O, Dieye AM, Diop I, Cisse A, and Diarra M
- Subjects
- Cellulose analogs & derivatives, Polymethacrylic Acids, Drug Delivery Systems, Insulin administration & dosage
- Abstract
Purpose: Diabetes Type I is a chronic disease requiring insulin repeated injections by parenteral during a lifetime. This method of administration as well as traumatic can be a problem for adherence of patients to treatment. In order to overcome these difficulties, we considered the development of therapeutic transdermal drug delivery (TTDD) of insulin., Material and Method: As active ingredient we used anhydrous human insulin Actarapid HM from Novo Nordisk laboratory, the excipients are ethyl cellulose, Eudragit RS 100 and butylphtalate. We developed two matrix Ethylcellulose/Eudragit in reports 1 and 2, in which are incorporated different proportions of insulin., Results: The study of the release of insulin in phosphate buffer at pH 7.4, showed a continuous release profiles strongly depending on Ethylcellulose/Eudragit report and the initial charge of insulin., Conclusion: This study shows that the matrix Ethylcellulose/Eudragit lends itself to the development of a controlled release of insulin. This allows us to continue this work by combining this matrix with other elements for achieving an insulin TTDD.
- Published
- 2009
31. [Pulmonary embolism: autopsy study of 73 cases in Senegal].
- Author
-
Kane A, Mboup MC, Diao M, Houda KY, Ba DM, Dia K, Dia MM, Diop IB, Sarr M, Kane A, and Ba SA
- Subjects
- Adolescent, Adult, Age Distribution, Aged, Autopsy, Child, Female, Humans, Male, Middle Aged, Retrospective Studies, Senegal, Young Adult, Pulmonary Embolism mortality, Pulmonary Embolism pathology
- Abstract
Introduction: The Pulmonary emblism is a vascular disease which is characterized by the more or less complete obstruction of one or several pulmonary arteritis and/or their branches by an embol. Very polymorphic affection, mortal in the massiv form, it has in the average forms of the atypical or misleading aspects which make its clinical diagnosis difficult. The diagnostic strategy of the pulmonary embolism remains incompletely solved. The objectives of this work are: --to evaluate the prevalence with the autopsy of the pulmonary embolism and its distribution according to the age, --to appreciate the correlation enters the ante and the post-mortems diagnoses., Patients and Methods: It is about a retrospective study, over 10 years period, having inclued the files of all the patients died in the various services of medicine or surgery of the university hospital of Aristide Le Dantec but also those transferred from outside of the hospital and at which the pulmonary diagnosis post-mortem of embolism was retained., Results: Sixty thirteen (73) cases of pulmonary embolism had been found during autopsies during the period of study (10 ans), that is to say a prevalence of 1.9%. The average was 35 years. The most representative age bracket was that ranging beetwin 21 and 30 years is 36% of the studied population. On the 73 indexed patients, 30 (41%) were transferred from outside of the hospital and 43 (59%) came from the servicies of medecine and surgery with a prevalance of the service of cardiology (26%). The correlation beetween ante-mortems diagnosis and the anatomical result was 11% for the whole of the patients incleded in the study. However, it was 42% for the sub-grup of patients comming from the service of cardiology., Conclusion: The prevalence with the autopsy of pulmonary embolism is weak. The clinical diagnosis of this affection is difficult even in a specilised service with a high rate of negatif forgeries. This pathology is very under- evaluated even in these services.
- Published
- 2008
32. Solidarity or financial sustainability: an analysis of the values of community-based health insurance subscribers and promoters in Senegal.
- Author
-
Ouimet MJ, Fournier P, Diop I, and Haddad S
- Subjects
- Delivery of Health Care, Diffusion of Innovation, Female, Health Services Accessibility, Humans, Interviews as Topic, Male, Senegal, Community Participation, Insurance, Health economics
- Abstract
Objectives: Although community-based health insurance (CBHI) seemed promising to improve access to health care, its implementation has been slow and laborious. We hypothesize that the existing tension between the competing objectives of solidarity and financial sustainability that are pursued by CBHI may partly account for this. This paper aims to evaluate if there is a gap between CBHI subscribers' values and their promoters', and to determine which characteristics of subscribers and CBHIs are associated with their values., Methods: A study of all Senegal CBHI organizations was undertaken in 2002. The analysis includes: 1) content of interviews with subscribers and promoters; and 2) multilevel logistical analysis of the links between characteristics of subscribers (n = 394) and organizations (n = 46) and composite indicators representing values (redistribution, solidarity when difficulties, solidarity between healthy and unhealthy)., Results: Promoters emphasize financial sustainability; subscribers are split between financial sustainability and solidarity. Men, polygamous families and individuals with a lower socio-professional status are twice as likely to be in favour of redistribution; subscribers who participate in decision-making and those who think their CBHI is facing difficulties are less in favour of solidarity. At CBHI level, although the variance was significant, none of the variables were retained., Conclusion: More attention should be given to reducing the gap between promoters' and subscribers' values, and to increasing member participation in the processes involved in implementing CBHI. This could help all actors involved to understand and improve determinants of enrolment in, and performance of CBHI, thus increasing access to health care for vulnerable populations in developing countries.
- Published
- 2007
33. [Primary arterial pulmonary hypertension and sildenafil: a case report from Dakar].
- Author
-
Bouldouyre M, Dia D, Ba FK, Diop IB, and Debonne JM
- Subjects
- Adult, Female, Humans, Purines therapeutic use, Senegal, Sildenafil Citrate, Hypertension, Pulmonary drug therapy, Piperazines therapeutic use, Sulfones therapeutic use, Vasodilator Agents therapeutic use
- Abstract
Introduction: We report our experience of using sildenafil in treatment on primary arterial pulmonary hypertension., Patient: This case concern a 38 years old senegalese woman. She was hospitalised for global cardiac failure with right signs predominance and grade IV dyspnea related to pulmonary hypertension., Results: No evident cause of the pulmonary hypertension had been found after explorations. Adding sildénafil to her symptomatic treatment provided fast favourable evolution quantified by clinical test and Doppler-ultrasound heart examination. However the patient died three month later by cerebral hemorrhage due to overdose of antivitamine K., Conclusion: We suggest using sildenafil in the treatment of primary arterial pulmonary hypertension on the way going to cardio-pulmonary transplantation.
- Published
- 2006
34. [Active rheumatic heart disease: findings from an 17-case series in the University Hospital Center of Dakar, Senegal].
- Author
-
Diao M, Kane A, Doumbia AS, Leye MM, Mbaye A, Kane A, Diop IB, Sarr M, Ba SA, and Diouf SM
- Subjects
- Adolescent, Adult, Child, Female, Hospitals, University, Humans, Male, Retrospective Studies, Senegal, Rheumatic Heart Disease diagnosis, Rheumatic Heart Disease drug therapy, Rheumatic Heart Disease epidemiology
- Abstract
This report is based on retrospective review of the charts of 18 patients with pre-existing active rheumatic heart disease compiled over a period of two years (January 2000 to December 2001). The purpose of this study was to determine the incidence of acute degenerative joint disease, to describe the clinical features and natural course of the disease, and to highlight the main points in the fight against degenerative joint disease and rheumatic heart disease. The prevalence of active rheumatic disease was 3.7%. Mean patient age was 15.5 years (range: 8 to 25 years). Female sex was predominant with 13 girls and 4 boys (sex ratio: 3.25). The most common clinical symptoms were migratory polyarthritis involving large joints in 14 cases (82.3%) and left heart insufficiency in 13 (76.4%). Additional clinical findings included oscillating fever in 8 cases (47.05%), tooth decay in 11 (73.3%), and poor buccodental hygiene in 14 (93.3%). Blood tests to evaluate inflammation demonstrated high values in all patients with mean ASLO titer of 950 UI/l, mean serum fibrin level of 7.8 g/l, and mean C-reactive protein level of 28.5 mg/l. The erythrocyte sedimentation rate was high in 15 cases (88.2%). In addition to showing heart valve disease, electrocardiography demonstrated first-degree atrioventricular block in 1 case. Chest x-ray revealed cardiomegaly in 15 cases (88.2%). Doppler ultrasonography of the heart showed isolated rheumatoid disease in 11 cases (64.7%). All patients responded favourably to treatment with corticosteroids and penicillin. The incidence of recurrence of active disease was high (70.5%) thus supporting use of high loading doses. Rheumatic heart disease is a public health problem in Africa and requires appropriate preventive measures.
- Published
- 2005
35. [Tricuspid valve stenosis. A prospective study of 35 cases].
- Author
-
Diaof M, Ba SA, Kane A, Sarr M, Diop IB, and Diouf SM
- Subjects
- Adolescent, Adult, Child, Diagnosis, Differential, Disease Progression, Echocardiography, Female, Humans, Incidence, Longitudinal Studies, Male, Middle Aged, Prognosis, Prospective Studies, Rheumatic Fever complications, Risk Factors, Senegal epidemiology, Heart Failure etiology, Tricuspid Valve Stenosis complications, Tricuspid Valve Stenosis diagnosis, Tricuspid Valve Stenosis pathology, Tricuspid Valve Stenosis therapy
- Abstract
Authors report the results of prospective and longitudinal study. The aims of this study were to evaluate among 35 patients, prevalence, diagnosis and treatment aspects of tricuspid stenosis (TS), as well as evolution and pronostical factors. The prevalence of TS was about 4.2%. The main clinical signs were: dyspnoea (94.2%), jugular veinus pulses (42.8%), superior cave syndrom (68.8%), diastolic rumble (74.3%). ECG showed sinus rhythm (51.4%), a right atrial hypertrophy (48.5%). Echocardiography showed tricuspid leaflets thickened (82.8%), a right atrial hypertrophy (48.5%), a mean gradient between right atrial and right ventricle: 8.6 +/- 3.14 mmHg (65.7%) and mean tricuspid area about 1.41 +/- 0.83 cm2 (continuous equation); about 1.74 +/- 1.29 cm2 (Hatle formula) and 1.11 0.84 cm2 (simplified Hatle formula). Aetiology was only rheumatic fever. After a follow-up of 8.53 +/- 6.06 months, the mortality rate was 28.5%. Complications were irreducible heart failure (24 cases), liver failure (2 cases) and stroke (3 cases). Factors associated with mortality were: severity of tricuspid stenosis and pulmonary hypertension, importance of dyspnea and heart failure (p < 0.041).
- Published
- 2004
36. [Spiral CT in aortic dissection].
- Author
-
Ba Diop S, Diop IB, Diakhate CI, Diao M, Alfidja A, Ly Ba A, Ndiaye A, Diop AN, Gueye B, Mbengue A, and Badiane M
- Subjects
- Adult, Diagnosis, Differential, Echocardiography, Doppler, Female, Humans, Male, Middle Aged, Sensitivity and Specificity, Aortic Dissection diagnostic imaging, Aortic Aneurysm diagnostic imaging, Tomography, Spiral Computed
- Abstract
Patients with suspected dissection of the thoracic aorta require immediate diagnostic evaluation so that urgent therapeutic interventions can begin. Two women with suspected aortic dissection and one man with abdominal aortic aneurysm underwent color-flow Doppler echocardiography and CT angiography with multiplanar reconstructions. Spiral CT showed ascending aortic dissection (type A Stanford) in two cases and descending aortic dissection (type B Stanford) in one case. It also access the visualization of the intimal flap, the extent of dissection, the size of the aorta, and the presence of pericardial fluid. CT angiography is an accurate diagnostic procedure for patients with suspected aortic dissection and possesses several advantages over other modalities such as transthoracic echocardiography, transesophageal echocardiography and aortography.
- Published
- 2004
37. [Electrocardiographic recording of long duration (Holter) of 24 hours during idiopathic cardiomyopathy of the peripartum].
- Author
-
Diao M, Diop IB, Kane A, Camara S, Kane A, Sarr M, Ba SA, and Diouf SM
- Subjects
- Adult, Chest Pain etiology, Cross-Sectional Studies, Female, Hemodynamics, Humans, Pregnancy, Prevalence, Risk Factors, Social Class, Tachycardia epidemiology, Tachycardia etiology, Electrocardiography, Ambulatory, Pregnancy Complications, Tachycardia pathology
- Abstract
The idiopathic myocardiopathy of the peripartum (IMPP) is a frequent disease in the Soudano-Sahelian zone of Africa whose evolution is loaded with many complications hemodynamic, thrombo-embolic and rhythmic. The prevalence and the meaning of the rhythm disorders are unknown. The aims of this prospective study are to measure and to describe the prevalence of the anomalies observed in Holter ECG of 24 hours. It's about a description cross-sectional study realized at the Cardiology Department (CHU Dakar) and 19 patients with IMPP were included, from October 2000 to July 2002. A recording ECG of 24 hours (Holter) was realized on all the patients. The average age was 29.4+/-6.9 years with a low socio-economic level (100%). The diagnosis of IMPP done before childbirth in 4 cases (21%) and the post partum on 15 patients (78.9%). The dyspnea was constant, the chest pain in 12 cases (63.1%) and palpitations in 8 cases (42%). The average rate of hemoglobin was of 10.85+/-2.05 g/dL. The standard electrocardiogram recorded a sinusal tachycardia (68.4%), a cavitary hypertrophy (78.8%), and disorders of the repolarization (47.3%). The cardiac echo-Doppler noted a cavitary dilatation (84.2%), a constant alteration of the left ventricular systolic function with a fraction of average ejection of 29.7+/-10.3%. The anatomy of the valves was normal. The recording Holter ECG of 24 hours recorded a sinusal tachycardia in 17 cases (89.4%), ventricular extrasystoles on 7 patients (36.8%), 4 cases of ventricular tachycardia non-sustained and double ventricular extrasystole on 1 patient, auricular extrasystoles in 4 cases (21%) and 1 case of auriculo-ventricular block of the first degree. The study of heart rate variability founded a mean value of 106 ms.
- Published
- 2004
38. [Role of transesophageal echocardiography in the diagnosis of aortic dissection. Report of 5 cases].
- Author
-
Diao M, Kane A, Sarr M, Ba-Diop S, Doucoure I, Diop IB, Kane A, Mbaye A, Leye MC, Ba SA, and Diouf SM
- Subjects
- Adult, Female, Humans, Male, Middle Aged, Aortic Dissection diagnostic imaging, Aortic Aneurysm, Thoracic diagnostic imaging, Echocardiography, Transesophageal
- Abstract
Aortic dissection is medical and surgical emergency. About 5 cases, the authors emphasized the role of transesophageal echocardiography in the diagnosis of aortic dissection. For all patients we realized a clinical examination, electrocardiogram, chest X ray, thoracic and transesophageal echocardiography and laboratory studies. Echocardiography were performed by an apparatus Hewlett Packard sonos 1000 with colour doppler and multiplanar transesophageal. Transesophageal echocardiography made the diagnosis by showing dilatation of aorta, intimal flap, false channel; this exam also allow to classify the aortic dissection.
- Published
- 2003
39. [Left atrial myxoma. Report of 2 cases operated in Senegal].
- Author
-
Diao M, Ba SA, Kane A, Ba A, Thiam O, Diop IB, Sarr M, and Diouf SM
- Subjects
- Female, Heart Atria, Humans, Middle Aged, Senegal, Heart Neoplasms surgery, Myxoma surgery
- Abstract
Cardiac tumours are rare and are dominated by left atrial myxoma. The authors report 2 cases of left atrial myxoma operated in the Cardiology department of Dakar (Senegal). Clinical signs were heart failure, cardiac sounds mimicking mitral valve disease and alteration of general state. The electrocardiogram showed sinus rhythm in 1 case and atrial flutter in the second case. The chest-x-ray show cardiac enlargement. Diagnosis was suggested by echocardiography and confirmed by anatomy. Evolution was favourable in one case and the other patient died.
- Published
- 2003
40. [The athlete's heart: an echocardiographic case-control study on Senegalese athletes].
- Author
-
Doumbia AS, Diallo TA, Kane A, Diao M, Diop IB, Sarr M, Ba SA, and Diouf SM
- Subjects
- Adult, Case-Control Studies, Cross-Sectional Studies, Humans, Male, Senegal, Basketball physiology, Bicycling physiology, Echocardiography
- Abstract
The aim of this work is to study the echocardiographic parameters of male trained athletes. It is about a case-control study comparing 3 groups: basketball players, cyclists and not sports healthy subjects. All the subjects benefited from an echocardiography (time motion, two-dimensional and pulse Doppler). The mean age is of 23.5 years for the cyclists group, 24 years for the basketball players and of 26.2 years for the control group. Compared with the control group, the left ventricular telediastolic dimensions, left ventricular mass index and the pulmonary flow velocity are higher in athletes group. The basketball players have a higher left ventricular diameter and parameter of systolic function than cyclists group. The septal diameter is higher in the cyclists group. This study finds some differencies in Senegalese athletes in the characteristics of the standard athletic heart syndrome.
- Published
- 2003
41. [Post myocardial infarction septal rupture. Report of 2 cases].
- Author
-
Kimbally-Kaky G, Ba A, Diao M, Thiam O, Kane A, Diop IB, Sarr M, Ba SA, and Diouf SM
- Subjects
- Aged, Echocardiography, Doppler, Fatal Outcome, Female, Humans, Male, Middle Aged, Heart Rupture, Post-Infarction diagnostic imaging
- Abstract
The authors report 2 cases of post myocardial infarction septal-rupture. There were one woman and one man aged respectively of 52 and 69 years. Risk factors were diabetes associated in one case with hypertension, and in the other case with tobacco addict. Both patients presented a ventricular septal defect murmur, and cardiac failure. Myocardial infarction (MI) was inaugural, semi-recent, and concemed interventricular septum or circumference of myocardium. Cardiac enzymes were high. Echocardiography showed a left ventricular apical aneurysm, and septal rupture. An abnormal blood flow pattern from left to right ventricle was visualized at Döppler. Medical treatment of Ml and cardiac failure were administrated. Surgery had not been possible. Both patients died respectively after 36 days and 4 days by cardiogenic shock.
- Published
- 2002
42. [Subvalvular left ventricular aneurysm. Report of 2 cases].
- Author
-
Kimbally-Kaky G, Ba A, Constantino C, Diao M, Kane A, Diop IB, Sarr M, Ba SA, and Diouf SM
- Subjects
- Child, Child, Preschool, Fatal Outcome, Female, Humans, Male, Senegal, Heart Aneurysm diagnosis
- Abstract
The authors report both Senegalese's cases of subvalvular left ventricular aneurysm (SVLVA). The aim of the study was to describe the clinical and paraclinical aspects of this disease. Mitral regurgitation an heart failure were constant. Beyond cardiomegaly observed in both patients, one of them presented vaulting of the left ventricle. In the two cases, electrocardisgram showed sinus rhythm, and biology an inflammatory syndrome. One patient had also tuberculosis. Transthoracic echocardiography showed an aneurysm situated in a mitral subvalvular position, thrombosed in one case. Medical treatment with furosemid and digoxin has been administrated. One patient received also drugs against tuberculosis. Surgery of aneurysm had not been possible. During the evolution, we have observed persistence of heart failure in one patient. The other one died, probably after a cerebral embolism. Autopsy confirmed the echocardiographic aspects and integrity of myocardium and coronary arteries.
- Published
- 2002
43. [Peripartum idiopathic myocardiopathy: prospective echocardiographic study].
- Author
-
Kane A, Dia AA, Diouf A, Dia D, Diop IB, Moreau JC, Faye EO, Sarr M, Ba SA, Diadhiou F, and Diouf SM
- Subjects
- Adolescent, Adult, Cardiomyopathies physiopathology, Female, Humans, Prospective Studies, Ultrasonography, Cardiomyopathies diagnostic imaging, Puerperal Disorders diagnostic imaging
- Abstract
Still frequent in Africa, the idiopathic peripartum cardiomyopathy (PPC) is the subject of only few prospective studies. The aim of this prospective work was to assess the echocardiographic abnormalities of the PPC and to determine on 26 patients the evolution and the prognostic factors of this disease. Six women had mild to moderate pericardial effusion. The abnormalities of the wall motion, constantly found, were diffuse in 20 cases (77.1%) and localized or prevalent on the interventricular septum or the left ventricular posterior wall in the other cases. The cardiac chambers were dilated in 24 cases (92.3%). Left ventricular hypertrophy was noted among 16 patients (61.5%); it was eccentric in 15 cases. The left ventricular systolic dysfunction was constant. The other abnormalities were: the abnormal left ventricular relaxation (one case), low mitral and aortic flow (12 cases), the mitral (21 cases) and tricuspid regurgitation (five cases). One noted a septal hypertrophy and an isolated dilatation of the right ventricle. The mean follow-up was 7.3 +/- 1 month (1-18 months). Two patients died at the 4th and 8th month. Among the 24 survivors, 11 had normalized were: the gestity (p = 0.01), the parity (p = 0.01), the cardiothoracic ratio (p = 0.04), the left ventricular volumes (p = 0.02), and the parameters of left ventricular function. The echocardiography of patients with PPC usually shows a pattern of dilated and hypokinetic cardiomyopathy, but many variations are possible. Most of the patients keep echocardiographic abnormalities after mean term follow-up.
- Published
- 2001
- Full Text
- View/download PDF
44. [Infective endocarditis at the University Hospital of Dakar. Clinical, outcome, and therapeutic features].
- Author
-
Diao M, Kane A, Ba SA, Bidani A, Diop IB, Sarr M, and Diouf SM
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Female, Humans, Male, Middle Aged, Prevalence, Retrospective Studies, Endocarditis, Bacterial diagnosis, Endocarditis, Bacterial drug therapy, Endocarditis, Bacterial epidemiology
- Abstract
Mainly because of rheumatic fever,infective endocarditis (IE) is frequent in our countries and is associated with many diagnostic and therapeutic problems. We perform a retrospective study on 86 cases of IE hospitalized from December 1986 to November 1996. The prevalence of IE is 4.3% and there is a female predominance (the sex ratio is 0.56). The mean age is 26.45+/-13.22 years. 74.4% of the patients have of low socioeconomic status. The mean duration of inhospital stay is 54 days and the average diagnosis retardation is 35 days. The source of infection is found in 19 cases (15 sources are dental). The main clinical signs are: fever (63.9%), anaemia (67.4%) and weight loss (38.3%). The underlying heart disease is mainly due to rheumatic valve regurgitation (95.3%). The blood culture find microbialagent in 12.7%. Echocardiography reveals vegetations in 69.7% of patients. The main complications are : heart failure (47.6%) and stroke (33.7%). The mortality rate is high (30.7%). The treatment is only medical, none of the patients has surgical repair. This study shows that IE is frequent and is associated with many complications and a high mortality rate. These observations amphasize the importance of prevention of rheumatic fever.
- Published
- 2001
45. [Cardiac tamponade. Clinical, paraclinical, outcome, and therapeutic features. Report of 15 cases].
- Author
-
Diao M, Ka TA, Kane A, Thiam O, Diop IB, Sarr M, Ba SA, and Diouf SM
- Subjects
- Adolescent, Adult, Aged, Child, Child, Preschool, Female, Humans, Male, Middle Aged, Prevalence, Prospective Studies, Cardiac Tamponade diagnosis, Cardiac Tamponade epidemiology, Cardiac Tamponade etiology
- Abstract
The authors perform a prospective study of 15 cases of cardiac tamponade in the Department of Cardiology of the University Hospital of Dakar (Senegal) from January to July 1999. The prevalence of cardiac tamponade is 4 %. The mean age is 33 years. There is no sex predominance. The clinical findings are: class III or IV NYHA dyspnea (86.6 %), pulsus paradoxus (66.6 %), and decrease intensity of the heart sounds (100 %). The electrocardiogram revealed sinus rhythm in 86.6 %, a low voltage of the QRS in all cases, and abnormalities of repolarization, mainly inverted T waves (73.3%). The echocardiography shows circumferential pericardial effusion (66.6 %), a "swinging heart" (53.3 %) and compression of right heart chambers (66.6 %). The main etiology was tuberculosis. The evolution is good after pericardiocentesis, surgical drainage and medical therapy. Cardiac tamponade is cardio-vascular emergency almost always due to tuberculosis with a good outcome if a prompt pericardiocentesis is performed.
- Published
- 2001
46. [Malaria prevention in the army: experience in senegal].
- Author
-
Fall IS, Ba-Fall KM, Gning SB, N'doye S, Diop I, and Wade B
- Subjects
- Africa epidemiology, Drug Resistance, Endemic Diseases, Humans, Malaria drug therapy, Malaria epidemiology, Senegal epidemiology, Malaria prevention & control, Military Personnel
- Abstract
The Senegalese army has acquired extensive experience in malaria prophylaxis in Sub-Saharan Africa. Until the early 90s, chloroquine-based drug prophylaxis was routinely administered during the transmission season. Currently this policy has been abandoned inside the country in favor of early treatment of infection. This change was made possible by the presence of qualified staff in all barracks. For extraterritorial interventions in Sub-Saharan Africa, drug prophylaxis is still used since most of the Senegalese population lives in the Sahelian zone without immunity to malaria and most host countries are in areas of high transmission. Treatment protocols have been defined in function of Plasmodium drug sensitivity in each country. For all West African nations except Nigeria, the protocol involves a combination of choroquine and proguanil at a dose of 300 mg per week and 200 mg per day respectively. For Central African nations in the south and east as well as for Nigeria, either mefloquine at a dose of 250 mg per week or doxycycline at a dose of 100 mg per day are used. Although acceptance has been slow, use of impregnated bednets is now an integral part of the prevention strategy. The insecticide used inside the country is deltametrin, but other products may be used during extraterritorial operations depending on vector sensitivity in the facilities host country. Vector control by spraying of insectides in and eliminating larval deposits is also an important part of the prevention strategy used by the Senegalese army which maintains a mobile unit for that purpose.
- Published
- 2001
47. [Short-term course under beta blockers of clinical and echocardiographic parameters in mitral stenosis in sinus rhythm].
- Author
-
Kane A, Djamadar SY, Affangla A, Diop IB, Sarr M, Ba SA, and Diouf SM
- Subjects
- Adolescent, Adult, Child, Female, Humans, Male, Mitral Valve Stenosis physiopathology, Prospective Studies, Time Factors, Ultrasonography, Adrenergic beta-Antagonists therapeutic use, Atenolol therapeutic use, Mitral Valve Stenosis diagnostic imaging, Mitral Valve Stenosis drug therapy
- Abstract
The purpose of this study is to evaluate the short-term benefit of a beta-blocker (atenolol) on clinical and echocardiographic parameters of patients presenting isolated or predominant mitral stenosis in sinus rhythm. It is a prospective study performed on 26 patients who have had a clinical and echocardiographic assessment before and 15 days after treatment by atenolol. After 15 days of beta-blocker treatment, there is a significant improvement of dyspnea (57.6% in class III or IV before beta-blockade versus 15.3% with atenolol; P = 0.001) and a significant decrease of the heart rate (83.3 +/- 15.2 versus 68.9 +/- 13.9; P = 0.001) and the diastolic blood pressure (8 mmHg +/- 1.3 versus 7.2 mmHg +/- 0.9; P = 0.01). The Doppler echocardiography shows a significant increase of the stroke volume calculated by the Doppler method (28.7 +/- 6.2 versus 38.6 +/- 9.7 mL; P = 0.04). There is an insignificant trend to an improvement of the left ventricular systolic function, an increase of cardiac output and the decrease of the mean transmitral gradient. The factors associated with the failure of beta-blocker treatment are: the right heart failure (P = 0.04) and the low diastolic blood pressure (P = 0.01). The beta-blockers could be a logical and effective treatment of patients with mitral stenosis waiting for balloon commissurotomy or surgery.
- Published
- 2000
48. [Intraventricular thrombosis complicating peri-partum idiopathic myocardiopathy].
- Author
-
Napporn AG, Kane A, Damorou JM, Dia AA, Diop IB, Sarr M, Ba SA, and Diouf SM
- Subjects
- Adult, Female, Heart Ventricles, Humans, Middle Aged, Pregnancy, Cardiomyopathies complications, Heart Diseases complications, Pregnancy Complications, Cardiovascular, Puerperal Disorders complications, Thrombosis complications
- Abstract
Ventricular thrombosis can complicate the development and worsen the prognosis in any case of hypokinetic dilated cardiomyopathy. In the present article, a study has been made of 6 reports of ventricular thrombosis selected out of 58 medical files on women with peri-partum idiopathic cardiomyopathy. Patient age ranged from 22 to 55 years. The clinical picture showed hypokinetic dilated cardiomyopathy, complicated by cardiac failure; with its onset during the last trimester of gestation or in the 6 months post-partum. In all patients, overall cardiac failure was observed, and in all cases the diagnosis of intracardiac thrombosis was made by echocardiography. In all 6 patients, a left ventricular apical thrombosis was detected. In 2 subjects, 2 and 3 left ventricular thrombi were respectively found. In 1 case, a left ventricular thrombosis was present. In another case, a right thrombosis associated with a left ventricular thrombosis was detected. Treatment was initiated with a combination of anticoagulants (heparin and K antivitamins), diuretic and vasodilatory treatment. The clinical outcome was favorable, with the disappearance of thrombi and signs of cardiac failure (between the 15th and 54th day). No embolic complication was observed. These findings clearly show the importance of prescribing an anticoagulant treatment as a preventive measure during PPICM. Even if severe embolic complications are a potential risk, anitcoagulant treatment can ensure a favorable outcome.
- Published
- 2000
49. [Biventricular thrombus complicating peripartum cardiomyopathy. A case report].
- Author
-
Damorou FJ, Kane A, Napporn G, Thiam O, Bidani A, Diop IB, Sarr M, Ba SA, and Diouf SM
- Subjects
- Adult, Angiotensin-Converting Enzyme Inhibitors therapeutic use, Cardiomyopathies diagnosis, Cardiomyopathies drug therapy, Cesarean Section, Combined Modality Therapy, Cough etiology, Diet, Sodium-Restricted, Diuretics therapeutic use, Dyspnea etiology, Echocardiography, Doppler, Echocardiography, Transesophageal, Electrocardiography, Female, Heart Diseases diagnosis, Heart Diseases drug therapy, Heart Ventricles, Humans, Leukocytosis etiology, Pregnancy, Puerperal Disorders diagnosis, Puerperal Disorders drug therapy, Thrombosis diagnosis, Thrombosis drug therapy, Treatment Outcome, Twins, Cardiomyopathies complications, Heart Diseases complications, Puerperal Disorders complications, Thrombosis complications
- Abstract
The authors report a case of a biventricular thrombus complicating peripartum cardiomyopathy in a 38 years old female. The diagnosis was done by bidimensionnal transthoracic echocardiography which showed 2 thrombi in the apical region of the right ventricle and in the anterior and lateral wall of the left ventricle. With treatment associating salt restriction, diuretics and angiotensin-converting-enzyme- inhibitors, the evolution was good: the thrombi disappeared at the first month for the left ventricular thrombi and after 45 days for the rignt ventricular thrombi. The patient didn't experience any embolic complication.
- Published
- 2000
50. [Peripartum heart failure: the underestimated role of frequent diseases in the Sudan-Sahelian area].
- Author
-
Kane A, Dia AA, Diop IB, Sarr M, Ba SA, and Diouf SM
- Subjects
- Adult, Africa, Northern epidemiology, Anemia complications, Angiotensin-Converting Enzyme Inhibitors therapeutic use, Captopril therapeutic use, Cardiotonic Agents therapeutic use, Causality, Developing Countries, Digoxin therapeutic use, Diuretics therapeutic use, Echocardiography, Female, Furosemide therapeutic use, Heart Failure diagnosis, Heart Failure drug therapy, Heart Failure etiology, Humans, Hypertension complications, Incidence, Pregnancy, Pregnancy Complications, Cardiovascular diagnosis, Pregnancy Complications, Cardiovascular drug therapy, Pregnancy Complications, Cardiovascular etiology, Puerperal Disorders diagnosis, Puerperal Disorders drug therapy, Puerperal Disorders etiology, Rheumatic Fever complications, Sudan epidemiology, Heart Failure epidemiology, Pregnancy Complications, Cardiovascular epidemiology, Puerperal Disorders epidemiology
- Abstract
Peripartum cardiomyopathy is rare in developped countries, but still frequent in Africa. It is defined as a heart failure occurring during peripartum, without any underlying etiology. Authors present 3 cases showing that heart failure before or after delivery may be due to causes which are frequent in the Sahelian area but generally misdiagnosed. Anemia, hypertension and rheumatic fever were the causes of heart failure in these 3 patients, but they were not apparent when the initial diagnosis was made. These observations emphasize that, despite the complex hypothesis trying to explain heart failure during the peripartum period, one should think about some frequent causes which can be misdiagnosed because of the pregnant state or the heart failure itself.
- Published
- 2000
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.