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3. Risk of metachronous peritoneal metastases after surgery for obstructive colon cancer: Multivariate analysis from a series of 1,085 patients

Author

Abba, J., Alfarai, A., d’Annunzio, E., Arvieux, C., Badic, B., Aumont, A., Balbo, G., Baque, P., Baraket, O., Bege, T., Bellinger, J., Bert, M., Bertrand, M., Beyer-Berjot, L., Blanc, B., Brouquet, A., Brunetti, F., Cabau, M., Catheline, J.M., Cazauran, J.B., Chatelain, E., Chau, A., Codjia, T., Collard, M., Corte, H., Couchard, A.C., David, A., Dazza, M., Dejeante, C., De La Villéon, B., Denost, Q., Diaz de Cerio, J.M., Djawad-Boumediene, B., Dubuisson, V., Duchalais, E., Dufour, F., Dumaine, A.S., Esposito, F., Etienne, J.C., Eveno, C., Fayssal, E., Fernoux, P., Fixot, K., Fuks, D., Gagnat, G., Goin, G., Goudard, Y., Grégoire, E., Guillem, P., Hamel, S., Heyd, B., Huart, E., Humeau, M., Issard, J., Jafar, Y., Kadoche, D., Kahn, X., Lacaze, L., Lailler, G., Lefèvre, J.H., Lizzi, V., Loge, L., Lupinacci, R., Mabrut, J.Y., Maes, B., Maggiori, L., Mallet, L., Mariol, P., Martre, P., Mauvais, F., Messière, A.S., Michot, N., Moszkowicz, D., Munoz, N., Ortega-Deballon, P., Paquette, B., Parc, Y., Pauleau, G., Pautrat, K., Peschaud, F., Philouze, G., Pichot-Delahaye, V., Piessen, G., Pitel, S., Rat, P., Regimbeau, J.M., Rivier, P., Roussel, E., Sage, P.Y., de Saint Roman, C., Sockeel, P., Susoko, L., Tetard, O., Tortajada, P., Tranchart, A., Tresallet, C., Trilling, B., Ulloa-Severino, B., Vauchaussade de Chaumont, A., Venara, A., Cazelles, Antoine, Tarhini, Ahmad, Sabbagh, Charles, Mege, Diane, Bridoux, Valérie, Lakkis, Zaher, Voron, Thibault, Abdalla, Solafah, Lecot, Frederik, Karoui, Mehdi, and Manceau, Gilles more...

Published
2025
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4. Robotic-assisted right colectomy. Official expert recommendations delivered under the aegis of the French Association of Surgery (AFC)

Author

Azagra, S., Mege, D., Di Saverio, S., de Chaisemartin, C., Espin-Basany, E., Gaujoux, S., Gómez-Ruiz, M., Gronnier, C., Karoui, M., Spinoglio, G., de’Angelis, N., Micelli Lupinacci, R., Abdalla, S., Genova, P., Beliard, A., Cotte, E., Denost, Q., Goasguen, N., Lakkis, Z., Lelong, B., Manceau, G., Meurette, G., Perrenot, C., Pezet, D., Rouanet, P., Valverde, A., and Pessaux, P. more...

Published
2022
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6. Link between postoperative ileus and anastomotic leakage: A structural equation modelling approach

Author

Abderrazak, M., Abolo, H., Abras, N., Aissou, M., Albertini, S., Alfonsi, P., Andre, A., Arimont, J.M., Arnalsteen, L., Atger, J., Attias, A., Aumont, O., Auvray, S., Bachmann, R., Barabino, G., Barsotti, P., Beauchesne, B., Beaupel, N., Beliard, A., Bellouard, A., Beloeil, H., Ben Salem, F., Benhamou, A., Billard, V., Binhas, M., Binot, D., Blache, J.L., Blet, A., Bongiovanni, J.P., Bonnal, A., Bonnet, M., Boret, H., Bossard, A.E., Bothereau, H., Bouarroudj, N., Bouayed, A., Bouchard, F., Boumadani, M., Bousquet, M., Bouygues, V., Bozio, G., Brek, A., Cadi, P., Caillon, P., Camerlo, A., Capito, C., Cardin, J.L., Castiglioni, M., Catinois, M.L., Cattan, P., Chambrier, C., Chambrier, G., Chapuis, O., Chauvin, M., Chokairi, S., Chopin Laly, X., Collange, V., Cotte, E., Cuellar, E., D'errico, E., Dahmani, S., Danan, M., De La Fontaine, C., De Wailly, P., Degauque, C., Delacoste, F., Denet, C., Denost, Q., Desaint, P., Descamps, E., Desfourneaux., V, Desmet, J., Desolneux, G., Dileon, S., Dolbeau, J.B., Douard, R., Dufour, F., Dupont-Bierre, E., Dupré, A., Entremont, A., Faucheron, J.L., Fernoux, P., Figuet, S., Finianos, A., Flamein, R., Fletcher, D., Fontes, J.P., Fourn, E., Gergeanu, S., Germain, A., Gignoux, B., Goater, P., Gres., P, Grigoroiu, M., Grillo, P., Guignard, B., Guinier, D., Guiot, J.L., Gutton, C., Hadjadj, H., Hail, K., Hausermann, M.H., Hennequin, S., Homsy-Hubert, B., Jambet, S., Janecki, T., Jannier-Guillou, V., Jaspart, J., Joly, F., Joris, J., Journe, F., Kattou, F., Kemoun, G., Khalaf, M., Klack, F., Kothonidis, K., Kurdi, O., Laforest, A., Lamblin, A., Lammens, S., Laporte, S., Launay-Savary, M.V., Le Maho, A.L., Lemée, J.M., Leonard, D., Leporrier, J., Lorin, J.L., Magne, E., Maisonnette, F., Malherbe, V., Manceau, G., Mariani, P., Massalou, D., Massard, J.L., Mauvais, F., Mbuyamba, J., Mbuyamba Katapile, J., Mehila, T., Meillat, H., Mergui, C., Michaud, P., Milou, F., Mirre, F., Mor Martinez, C., Mouchon, S., Mouilhade, F., Nguyen, Y.L., Ostermann Bucher, S., Page, M., Parent, S., Payen, A.L., Pedicone, R., Peluchon, P., Pichot-Delahaye, V., Piquard, A., Pirlet, I., Plard, L., Poiblanc, M., Poinas, G., Poincenot, J., Ponchel, C., Pontallier, A., Pop, R., Potiron, E., Proske, J.M., Prunet, B., Ras, E., Raspado, O., Raux, M., Regimbeau, J.M., Remue, C., Renacco, F., Riboud, R., Richard-Payen, A.L., Rio, D., Sage, M., Sage, P.Y., Saint Denis, M., Salaun, P., Samyn, B., Sbai Idrissi, M., Schmitt, G., Secq, E., Seddiki, A., Sens, N., Sirieix, D., Siriser, F., Tarcea, M., Tavernier, M., Tete, B., Theissen-Laval, O., Thevenot, A., Thievenaz, R., Vacher, B., Verhaeghe, R., Verrier, J.F., Vieuille, C., Voilin, C., Vuagnat, C., Zaepfel, S., Venara, Aurélien, Hamel, Jean-Francois, Beyer-Berjot, Laura, Vignaud, Timothée, and Slim, Karem more...

Published
2021
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16. Revue de Presse

Author

Walter, T., de Parades, V., Musquer, N., Denost, Q., Cotte, E., Panis, Y., and Zeitoun, J. D.

Published
2017
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18. Revue de presse

Author

de Parades, V., Panis, Y., Meurette, G., Zeitoun, J. -D., Siproudhis, L., Denost, Q., Lefevre, J., Cotte, E., Lièvre, A., and Simon, M.

Published
2017
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19. Revue de presse

Author

de Parades, V., Panis, Yves, Pigot, F., Zeitoun, J. D., Lefevre, J. H., Bouchard, D., Cotte, E., Denost, Q., and Senéjoux, A.

Published
2016
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20. DOP037 Postoperative anti-TNF therapy is associated with a significant reduction of both endoscopic and clinical recurrence following surgery for ileocolonic Crohn’s disease: results of a prospective nationwide cohort conducted by the GETAID chirurgie group

Author

Maggiori, L, Brouquet, A, Zerbib, P, Lefevre, J, Denost, Q, Germain, A, Cotte, E, Beyer-Berjot, L, Munoz-Bongrand, N, Desfourneaux, V, Rahili, A, Duffas, J -P, Pautrat, K, Denet, C, Bridoux, V, Meurette, G, Faucheron, J -L, Loriau, J, Guillon, F, Vicaut, E, Panis, Y, and Benoist, S more...

Published
2018
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22. Revue de presse

Author

Senéjoux, A., de Parades, V., Walter, T., Bouchard, D., Panis, Y., Lièvre, A., Zeitoun, J. D., Denost, Q., and Cotte, E.

Published
2016
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24. Learning curve for robotic‐assisted total mesorectal excision: a multicentre, prospective study.

Author

Arquillière, J., Dubois, A., Rullier, E., Rouanet, P., Denost, Q., Celerier, B., Pezet, D., Passot, G., Aboukassem, A., Colombo, P. E., Mourregot, A., Carrere, S., Vaudoyer, D., Gourgou, S., Gauthier, L., and Cotte, E. more...

Subjects
LYMPHADENECTOMY, RECTAL cancer, RECTAL surgery, SURGICAL margin, ABDOMINAL surgery, LONGITUDINAL method
Abstract

Aim: Robotic‐assisted surgery (RAS) is becoming increasingly important in colorectal surgery. Recognition of the short, safe learning curve (LC) could potentially improve implementation. We evaluated the extent and safety of the LC in robotic resection for rectal cancer. Method: Consecutive rectal cancer resections (January 2018 to February 2021) were prospectively included from three French centres, involving nine surgeons. LC analyses only included surgeons who had performed more than 25 robotic rectal cancer surgeries. The primary endpoint was operating time LC and the secondary endpoint conversion rate LC. Interphase comparisons included demographic and intraoperative data, operating time, conversion rate, pathological specimen features and postoperative morbidity. Results: In 174 patients (69% men; mean age 62.6 years) the mean operating time was 334.5 ± 92.1 min. Operative procedures included low anterior resection (n = 143) and intersphincteric resection (n = 31). For operating time, there were two or three (centre‐dependent) LC phases. After 12–21 cases (learning phase), there was a significant decrease in total operating time (all centres) and an increase in the number of harvested lymph nodes (two centres). For conversion rate, there were two or four LC phases. After 9–14 cases (learning phase), the conversion rate decreased significantly in two centres; in one centre, there was a nonsignificant decrease despite the treatment of significantly more obese patients and patients with previous abdominal surgery. There were no significant differences in interphase comparisons. Conclusion: The LC for RAS in rectal cancer was achieved after 12–21 cases for the operating time and 9–14 cases for the conversion rate. RAS for rectal cancer was safe during this time, with no interphase differences in postoperative complications and circumferential resection margin. [ABSTRACT FROM AUTHOR] more...

Published
2023
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25. Randomized clinical trial of sacral nerve stimulation for refractory constipation

Author

Zerbib, F., Siproudhis, L., Lehur, P.‐A., Germain, C., Mion, F., Leroi, A.‐M., Coffin, B., Le Sidaner, A., Vitton, V., Bouyssou‐Cellier, C., Chene, G., Zerbib, F., Simon, M., Denost, Q., Lepicard, P., Lehur, P.‐A., Meurette, G., Wyart, V., Kubis, C., Mion, F., Roman, S., Damon, H., Barth, X., Leroi, A.‐M., Bridoux, V., Gourcerol, G., Coffin, B., Castel, B., Gorbatchef, C., Sidaner, Anne Le, Mathonnet, M., Vitton, V., Lesavre, N., Orsoni, P., Siproudhis, L., Brochard, C., and Desfourneaux, V. more...

Published
2017
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42. Robotic-assisted right colectomy. Official expert recommendations delivered under the aegis of the French Association of Surgery (AFC).

Author

de'Angelis, N., Micelli Lupinacci, R., Abdalla, S., Genova, P., Beliard, A., Cotte, E., Denost, Q., Goasguen, N., Lakkis, Z., Lelong, B., Manceau, G., Meurette, G., Perrenot, C., Pezet, D., Rouanet, P., Valverde, A., and Pessaux, P. more...

Subjects
COLECTOMY, MINIMALLY invasive procedures, PROGRESSION-free survival, SURGERY, ABDOMINAL surgery, OVERALL survival
Abstract

Twenty-seven experts under the aegis of the French Association of Surgery (AFC) offer this reference system with formalized recommendations concerning the performance of right colectomy by robotic approach (RRC). For RRC, experts suggest patient installation in the so-called "classic" or "suprapubic" setup. For patients undergoing right colectomy for a benign pathology or cancer, RRC provides no significant benefit in terms of intra-operative blood loss, intra-operative complications or conversion rate to laparotomy compared to laparoscopy. At the same time, RRC is associated with significantly longer operating times. Data from the literature are insufficient to define whether the robot facilitates the performance of an intra-abdominal anastomosis, but the robotic approach is more frequently associated with an intra-abdominal anastomosis than the laparoscopic approach. Experts also suggest that RRC offers a benefit in terms of post-operative morbidity compared to right colectomy by laparotomy. No benefit is retained in terms of mortality, duration of hospital stay, histological results, overall survival or disease-free survival in RRC performed for cancer. In addition, RRC should not be performed based on the cost/benefit ratio, since RRC is associated with significantly higher costs than laparoscopy and laparotomy. Future research in the field of RRC should consider the evaluation of patient-targeted parameters such as pain or quality of life and the technical advantages of the robot for complex procedural steps, as well as surgical and oncological results. [ABSTRACT FROM AUTHOR] more...

Published
2022
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43. Low-pressure versus standard pressure laparoscopic colorectal surgery (PAROS trial): a phase III randomized controlled trial.

Author

Celarier, S., Monziols, S., Célérier, B., Assenat, V., Carles, P., Napolitano, G., Laclau-Lacrouts, M., Rullier, E., Ouattara, A., and Denost, Q.

Subjects
LAPAROSCOPIC surgery, PROCTOLOGY, VISUAL analog scale, COLECTOMY, POSTOPERATIVE pain, ONCOLOGIC surgery
Abstract

Trial design: This is a phase III, double-blind, randomized, controlled trial. Methods: In this trial, patients with laparoscopic colectomy were assigned to either low pressure (LP: 7 mmHg) or standard pressure (SP: 12 mmHg) at a ratio of 1 : 1. The aim of this trial was to assess the impact of low-pressure pneumoperitoneum during laparoscopic colectomy on postoperative recovery. The primary endpoint was the duration of hospital stay. The main secondary endpoints were postoperative pain, consumption of analgesics and postoperative morbidity. Results: Some 138 patients were enrolled, of whom 11 were excluded and 127 were analysed: 62 with LP and 65 with SP. Duration of hospital stay (3 versus 4 days; P=0.010), visual analog scale (0.5 versus 2.0; P=0.008) and analgesic consumption (level II: 73 versus 88 per cent; P=0.032; level III: 10 versus 23 per cent; P=0.042) were lower with LP. Morbidity was not significantly different between the two groups (10 versus 17 per cent; P=0.231). Conclusion: Using low-pressure pneumoperitoneum in laparoscopic colonic resection improves postoperative recovery, shortening the duration of hospitalization and decreasing postoperative pain and analgesic consumption. This suggests that low pressure should become the standard of care for laparoscopic colectomy. [ABSTRACT FROM AUTHOR] more...

Published
2021
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44. Impact of early biochemical diagnosis of anastomotic leakage after rectal cancer surgery: long-term results from GRECCAR 5 trial.

Author

Denost, Q., Rouanet, P., Faucheron, J.-L., Panis, Y., Meunier, B., Cotte, E., Meurette, G., Portier, G., Sabbagh, C., Loriau, J., Benoist, S., Piessen, G., Sielezneff, I., Lelong, B., Mauvais, F., Romain, B., Barussaud, M.-L., Capdepont, M., Laurent, C., and Rullier, E. more...

Subjects
*ONCOLOGIC surgery, *RECTAL cancer, *EARLY diagnosis, *RECTAL surgery, *LEAKAGE
Published
2021
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47. Y a-t-il un intérêt à réaliser une chimiothérapie adjuvante dans la prise en charge des adénocarcinomes du rectum ypT3N0 ayant une stérilisation ganglionnaire après radiochimiothérapie néoadjuvante ?

Author

Allart, K., Manceau, G., Sabbagh, C., Agostini, J., Bachet, J.B., Vaillant, J.C., Karoui, M., Denost, Q., Tekkis, P., Rullier, E., Dumont, F., Goere, D., Brouquet, A., Penna, C., Peschaud, F., Benoist, S., Gracient, A., Vychnevskaia, K., and Regimbeau, J.M. more...

Published
2021
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50. A Reappraisal of Outcome of Elective Surgery After Successful Non-Operative Management of an Intra-Abdominal Abscess Complicating Ileocolonic Crohn's Disease: A Subgroup Analysis of a Nationwide Prospective Cohort.

Author

Collard, M K, Benoist, S, Maggiori, L, Zerbib, P, Lefevre, J H, Denost, Q, Germain, A, Cotte, E, Beyer-Berjot, L, Corté, H, Desfourneaux, V, Rahili, A, Duffas, J P, Pautrat, K, Denet, C, Bridoux, V, Meurette, G, Faucheron, J L, Loriau, J, and Souche, R more...

Abstract

Background and Aims Few prospective data exist on outcomes of surgery in Crohn's disease [CD] complicated by an intra-abdominal abscess after resolution of this abscess by antibiotics optionally combined with drainage. Methods From 2013 to 2015, all patients undergoing elective surgery for CD after successful non-operative management of an intra-abdominal abscess [Abscess-CD group] were selected from a nationwide multicentre prospective cohort. Resolution of the abscess had to be computed tomography/magnetic resonance-proven prior to surgery. Abscess-CD group patients were 1:1 matched to uncomplicated CD [Non-Penetrating-CD group] using a propensity score. Postoperative results and long-term outcomes were compared between the two groups. Results Among 592 patients included in the registry, 63 [11%] fulfilled the inclusion criteria. The abscess measured 37 ± 20 mm and was primarily managed with antibiotics combined with drainage in 14 patients and nutritional support in 45 patients. At surgery, a residual fluid collection was found in 16 patients [25%]. Systemic steroids within 3 months before surgery [ p  = 0.013] and the absence of preoperative enteral support [ p  = 0.001] were identified as the two significant risk factors for the persistence of a fluid collection. After propensity score matching, there was no significant difference between the Abscess-CD and Non-Penetrating-CD groups in the rates of primary anastomosis [84% vs 90% respectively, p  = 0.283], overall [28% vs 15% respectively, p  = 0.077] and severe postoperative morbidity [7% vs 7% respectively, p  = 1.000]. One-year recurrence rates for endoscopic recurrence were 41% in the Abscess-CD and 51% in the Non-Penetrating-CD group [ p  = 0.159]. Conclusions Surgery after successful non-operative management of intra-abdominal abscess complicating CD provides good early and long-term outcomes. [ABSTRACT FROM AUTHOR] more...

Published
2021
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