Search

Your search keyword '"Delzenne N"' showing total 227 results
Start Over Author "Delzenne N" Publication Type Academic Journals
227 results on '"Delzenne N"'

27. The biochemistry of oligofructose, a nondigestible fiber: an approach to calculate its caloric value

Author

Roberfroid, M., Gibson, G.R., and Delzenne, N.

Subjects
Fiber in human nutrition -- Physiological aspects, Food/cooking/nutrition
Abstract

Oligofructose, a product of inulin, occurs naturally in a variety of foods. The mean daily consumption of oligofructose and inulin by North Americans is between 2-8 g per person per day. The caloric value of a fructosyl unit of oligofructose is 25-35% of a digested molecule of hexose, or approximately one kca/g.

Published
1993

32. The FiberTAG project: Tagging dietary fibre intake by measuring biomarkers related to the gut microbiota and their interest for health.

Author

Neyrinck, A. M., Rodriguez, J., Vinoy, S., Maquet, V., Walter, J., Bischoff, S. C., Laville, M., and Delzenne, N. M.

Subjects
BIOMARKERS, BLOOD-brain barrier, FERMENTATION, DIETARY fiber, GLUCANS, INGESTION, METABOLIC disorders, NUTRITIONAL requirements, GUT microbiome, PREBIOTICS
Abstract

The scientific rationale for dietary fibre intake recommendations comes from the recognition of their benefits for health based on studies first published many years ago. It remains unclear which are the key physiological effects generated by dietary fibre in view of the diversity of the food components considered as dietary fibre, of the relevance of their classification (soluble and insoluble) and from the recent discoveries putting forward their interactions with the gut microbiota. The project FiberTAG (Joint Programming Initiative 'A Healthy Diet for a Healthy Life' 2017–2020 www.fibertag.eu/) aims to establish a set of biomarkers (markers of gut barrier function and bacterial co‐metabolites including volatile compounds and lipid derivatives), measured in different biological compartments (faeces, blood or breath) linking dietary fibre intake and gut microbiota‐related health effects. The FiberTAG consortium brings together academic and industrial partners from Belgium, France, Germany and Canada to share data and samples obtained from existing as well as new intervention studies in order to evaluate the relevance of such biomarkers. The FiberTAG consortium is currently working on five existing cohorts (prospective observational or nutritional interventions in healthy or obese patients), and a number of new intervention studies to analyse the effect of insoluble dietary fibre (wheat bran and chitin‐glucan, provided by the industrial partners) in healthy individuals or in obese patients at high cardiometabolic risk. [ABSTRACT FROM AUTHOR]

Published
2020
Full Text
View/download PDF

36. Contribution of the gut microbiota to the regulation of host metabolism and energy balance: a focus on the gut-liver axis.

Author

Delzenne, N. M., Knudsen, C., Beaumont, M., Rodriguez, J., Neyrinck, A. M., and Bindels, L. B.

Subjects
LIVER physiology, ENERGY metabolism, BIOLOGICAL models, RESEARCH, PREBIOTICS, LIVER, FATTY liver, ANIMAL experimentation, INFLAMMATION, RESEARCH methodology, EVALUATION research, MEDICAL cooperation, PROBIOTICS, COMPARATIVE studies, MICE
Abstract

This review presents mechanistic studies performed in vitro and in animal models, as well as data obtained in patients that contribute to a better understanding of the impact of nutrients interacting with the gut microbiota on metabolic and behavioural alterations linked to obesity. The gut microbiota composition and function are altered in several pathological conditions including obesity and related diseases i.e. non-alcoholic fatty liver diseases (NAFLD). The gut-liver axis is clearly influenced by alterations of the gut barrier that drives inflammation. In addition, recent papers propose that specific metabolites issued from the metabolic cooperation between the gut microbes and host enzymes, modulate inflammation and gene expression in the liver. This review illustrates how dietary intervention with prebiotics or probiotics influences host energy metabolism and inflammation. Indeed, intervention studies are currently underway in obese and NAFLD patients to unravel the relevance of the changes in gut microbiota composition in the management of metabolic and behavioural disorders by nutrients interacting with the gut microbiota. In conclusion, diet is among the main triggers of NAFLD and the gut microbiota is modified accordingly, underlining the importance of the concomitant study of the nutrients and microbial impact on liver health and metabolism, in order to propose innovative, clinically relevant, therapeutic approaches. [ABSTRACT FROM AUTHOR]

Published
2019
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results