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Androgen-secreting adrenal neoplasms have a low incidence, usually secrete multiple hormones, and may present with hirsutism, acne, and alopecia. We report an exceedingly rare case of a purely dehydroepiandrosterone-sulfate (DHEA-S) secreting adrenal neoplasm found incidentally on cross sectional imaging. The clinical, biochemical, and pathologic findings of this neoplasm are described.

Purpose: This investigation explored factors associated with premenstrual syndrome (PMS) in minority women, and compared the response of minority and non-minority women supplemented with omega-3 fatty acids (FA) in the form of fish oil. Methods: This descriptive, correlational, retrospective pilot was a secondary data analysis. Participants consuming 2 g of fish oil/d (n = 15) in the larger study were included. The Moos Menstrual Distress Questionnaire (MMDQ) was assessed monthly for two months to acquire a mean baseline MMDQ score. The total sample was stratified to evaluate racial variations in PMS symptoms (non-minority, n = 7; minority, n = 8). MMDQ score at 5 months was compared to the mean baseline score within each group. Results: Fish oil supplementation significantly reduced PMS symptoms in both groups (non-minority p = 0.002; minority p = 0.046) with a large effect of 1.4 for both groups. Mean MMDQ total scores were not significantly different between groups at 5 months. Conclusions: This pilot evidence of improved PMS symptoms in minority and non-minority groups related to fish oil supplementation supports a universal treatment approach and highlights need for a larger-scale investigation.