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362 results on '"Chaubey, Gyaneshwer"'

13. The matrilineal ancestry of Nepali populations

Author

Basnet, Rajdip, Rai, Niraj, Tamang, Rakesh, Awasthi, Nagendra Prasad, Pradhan, Isha, Parajuli, Pawan, Kashyap, Deepak, Reddy, Alla Govardhan, Chaubey, Gyaneshwer, Das Manandhar, Krishna, Shrestha, Tilak Ram, and Thangaraj, Kumarasamy

Published
2023
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19. Genomic analyses inform on migration events during the peopling of Eurasia

Author

Pagani, Luca, Lawson, Daniel John, Jagoda, Evelyn, Mörseburg, Alexander, Eriksson, Anders, Mitt, Mario, Clemente, Florian, Hudjashov, Georgi, DeGiorgio, Michael, Saag, Lauri, Wall, Jeffrey D, Cardona, Alexia, Mägi, Reedik, Sayres, Melissa A Wilson, Kaewert, Sarah, Inchley, Charlotte, Scheib, Christiana L, Järve, Mari, Karmin, Monika, Jacobs, Guy S, Antao, Tiago, Iliescu, Florin Mircea, Kushniarevich, Alena, Ayub, Qasim, Tyler-Smith, Chris, Xue, Yali, Yunusbayev, Bayazit, Tambets, Kristiina, Mallick, Chandana Basu, Saag, Lehti, Pocheshkhova, Elvira, Andriadze, George, Muller, Craig, Westaway, Michael C, Lambert, David M, Zoraqi, Grigor, Turdikulova, Shahlo, Dalimova, Dilbar, Sabitov, Zhaxylyk, Sultana, Gazi Nurun Nahar, Lachance, Joseph, Tishkoff, Sarah, Momynaliev, Kuvat, Isakova, Jainagul, Damba, Larisa D, Gubina, Marina, Nymadawa, Pagbajabyn, Evseeva, Irina, Atramentova, Lubov, Utevska, Olga, Ricaut, François-Xavier, Brucato, Nicolas, Sudoyo, Herawati, Letellier, Thierry, Cox, Murray P, Barashkov, Nikolay A, Škaro, Vedrana, Mulahasanovic´, Lejla, Primorac, Dragan, Sahakyan, Hovhannes, Mormina, Maru, Eichstaedt, Christina A, Lichman, Daria V, Abdullah, Syafiq, Chaubey, Gyaneshwer, Wee, Joseph TS, Mihailov, Evelin, Karunas, Alexandra, Litvinov, Sergei, Khusainova, Rita, Ekomasova, Natalya, Akhmetova, Vita, Khidiyatova, Irina, Marjanović, Damir, Yepiskoposyan, Levon, Behar, Doron M, Balanovska, Elena, Metspalu, Andres, Derenko, Miroslava, Malyarchuk, Boris, Voevoda, Mikhail, Fedorova, Sardana A, Osipova, Ludmila P, Lahr, Marta Mirazón, Gerbault, Pascale, Leavesley, Matthew, Migliano, Andrea Bamberg, Petraglia, Michael, Balanovsky, Oleg, Khusnutdinova, Elza K, Metspalu, Ene, Thomas, Mark G, Manica, Andrea, Nielsen, Rasmus, Villems, Richard, Willerslev, Eske, Kivisild, Toomas, and Metspalu, Mait

Subjects
Human Genome, Biotechnology, Genetics, Generic health relevance, Africa, Animals, Asia, Datasets as Topic, Estonia, Europe, Fossils, Gene Flow, Genetics, Population, Genome, Human, Genomics, Heterozygote, History, Ancient, Human Migration, Humans, Native Hawaiian or Other Pacific Islander, Neanderthals, New Guinea, Population Dynamics, Racial Groups, General Science & Technology
Abstract

High-coverage whole-genome sequence studies have so far focused on a limited number of geographically restricted populations, or been targeted at specific diseases, such as cancer. Nevertheless, the availability of high-resolution genomic data has led to the development of new methodologies for inferring population history and refuelled the debate on the mutation rate in humans. Here we present the Estonian Biocentre Human Genome Diversity Panel (EGDP), a dataset of 483 high-coverage human genomes from 148 populations worldwide, including 379 new genomes from 125 populations, which we group into diversity and selection sets. We analyse this dataset to refine estimates of continent-wide patterns of heterozygosity, long- and short-distance gene flow, archaic admixture, and changes in effective population size through time as well as for signals of positive or balancing selection. We find a genetic signature in present-day Papuans that suggests that at least 2% of their genome originates from an early and largely extinct expansion of anatomically modern humans (AMHs) out of Africa. Together with evidence from the western Asian fossil record, and admixture between AMHs and Neanderthals predating the main Eurasian expansion, our results contribute to the mounting evidence for the presence of AMHs out of Africa earlier than 75,000 years ago.

Published
2016

24. A recent bottleneck of Y chromosome diversity coincides with a global change in culture

Author

Karmin, Monika, Saag, Lauri, Vicente, Mário, Sayres, Melissa A Wilson, Järve, Mari, Talas, Ulvi Gerst, Rootsi, Siiri, Ilumäe, Anne-Mai, Mägi, Reedik, Mitt, Mario, Pagani, Luca, Puurand, Tarmo, Faltyskova, Zuzana, Clemente, Florian, Cardona, Alexia, Metspalu, Ene, Sahakyan, Hovhannes, Yunusbayev, Bayazit, Hudjashov, Georgi, DeGiorgio, Michael, Loogväli, Eva-Liis, Eichstaedt, Christina, Eelmets, Mikk, Chaubey, Gyaneshwer, Tambets, Kristiina, Litvinov, Sergei, Mormina, Maru, Xue, Yali, Ayub, Qasim, Zoraqi, Grigor, Korneliussen, Thorfinn Sand, Akhatova, Farida, Lachance, Joseph, Tishkoff, Sarah, Momynaliev, Kuvat, Ricaut, François-Xavier, Kusuma, Pradiptajati, Razafindrazaka, Harilanto, Pierron, Denis, Cox, Murray P, Sultana, Gazi Nurun Nahar, Willerslev, Rane, Muller, Craig, Westaway, Michael, Lambert, David, Skaro, Vedrana, Kovačevic´, Lejla, Turdikulova, Shahlo, Dalimova, Dilbar, Khusainova, Rita, Trofimova, Natalya, Akhmetova, Vita, Khidiyatova, Irina, Lichman, Daria V, Isakova, Jainagul, Pocheshkhova, Elvira, Sabitov, Zhaxylyk, Barashkov, Nikolay A, Nymadawa, Pagbajabyn, Mihailov, Evelin, Seng, Joseph Wee Tien, Evseeva, Irina, Migliano, Andrea Bamberg, Abdullah, Syafiq, Andriadze, George, Primorac, Dragan, Atramentova, Lubov, Utevska, Olga, Yepiskoposyan, Levon, Marjanovic´, Damir, Kushniarevich, Alena, Behar, Doron M, Gilissen, Christian, Vissers, Lisenka, Veltman, Joris A, Balanovska, Elena, Derenko, Miroslava, Malyarchuk, Boris, Metspalu, Andres, Fedorova, Sardana, Eriksson, Anders, Manica, Andrea, Mendez, Fernando L, Karafet, Tatiana M, Veeramah, Krishna R, Bradman, Neil, Hammer, Michael F, Osipova, Ludmila P, Balanovsky, Oleg, Khusnutdinova, Elza K, Johnsen, Knut, Remm, Maido, Thomas, Mark G, Tyler-Smith, Chris, Underhill, Peter A, Willerslev, Eske, Nielsen, Rasmus, Metspalu, Mait, Villems, Richard, and Kivisild, Toomas

Subjects
Biological Sciences, Genetics, Human Genome, Base Sequence, Chromosomes, Human, Y, DNA, Mitochondrial, Evolution, Molecular, Genetic Variation, Genetics, Population, Haplotypes, Humans, Male, Models, Genetic, Phylogeny, Racial Groups, Sequence Analysis, DNA, Medical and Health Sciences, Bioinformatics
Abstract

It is commonly thought that human genetic diversity in non-African populations was shaped primarily by an out-of-Africa dispersal 50-100 thousand yr ago (kya). Here, we present a study of 456 geographically diverse high-coverage Y chromosome sequences, including 299 newly reported samples. Applying ancient DNA calibration, we date the Y-chromosomal most recent common ancestor (MRCA) in Africa at 254 (95% CI 192-307) kya and detect a cluster of major non-African founder haplogroups in a narrow time interval at 47-52 kya, consistent with a rapid initial colonization model of Eurasia and Oceania after the out-of-Africa bottleneck. In contrast to demographic reconstructions based on mtDNA, we infer a second strong bottleneck in Y-chromosome lineages dating to the last 10 ky. We hypothesize that this bottleneck is caused by cultural changes affecting variance of reproductive success among males.

Published
2015

31. Genotype-Phenotype Study of the Middle Gangetic Plain in India Shows Association of rs2470102 with Skin Pigmentation

Author

Mishra, Anshuman, Nizammuddin, Sheikh, Mallick, Chandana Basu, Singh, Sakshi, Prakash, Satya, Siddiqui, Niyamat Ali, Rai, Niraj, Carlus, S. Justin, Sudhakar, Digumarthi V.S., Tripathi, Vishnu P., Möls, Märt, Kim-Howard, Xana, Dewangan, Hemlata, Mishra, Abhishek, Reddy, Alla G., Roy, Biswajit, Pandey, Krishna, Chaubey, Gyaneshwer, Das, Pradeep, Nath, Swapan K., Singh, Lalji, and Thangaraj, Kumarasamy

Published
2017
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35. Reconstructing the demographic history of the Himalayan and adjoining populations

Author

Tamang, Rakesh, Chaubey, Gyaneshwer, Nandan, Amrita, Govindaraj, Periyasamy, Singh, Vipin Kumar, Rai, Niraj, Mallick, Chandana Basu, Sharma, Vishwas, Sharma, Varun Kumar, Shah, Anish M., Lalremruata, Albert, Reddy, Alla G., Rani, Deepa Selvi, Doviah, Pilot, Negi, Neetu, Hadid, Yarin, Pande, Veena, Vishnupriya, Satti, van Driem, George, Behar, Doron M., Sharma, Tikaram, Singh, Lalji, Villems, Richard, and Thangaraj, Kumarasamy

Published
2018
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39. The peopling of Lakshadweep Archipelago

Author

Mustak, Mohammed S., Rai, Niraj, Naveen, Mohan Rao, Prakash, Satya, Carlus, S. Justin, Pasupuleti, Nagarjuna, Srivastava, Anshika, Singh, Prajjval Pratap, Babu, Idrees, Dubey, Pavan Kumar, Chaubey, Gyaneshwer, and Thangaraj, Kumarasamy

Published
2019
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43. Preliminary Status and Distribution of Indian Grey Wolf (Canis lupus pallipes) in the Bhal Region of Gujarat.

Author

DESAI, SHAILESH KUMAR, GOSAI, CHIRAGBALA M., and CHAUBEY, GYANESHWER

Abstract

The Indian grey wolf is a crucial apex predator in India's semi-arid region, but their wide range and elusive behavior make population estimation challenging. Accurate population estimation is essential for effective management and conservation efforts. Our study focused on the bhal region of Gujarat and used local community information validated by ground surveys. Our estimates suggest a population of 64-88 wolves with a density of 0.021-0.029 wolf/km2. However, despite the region's continued distribution, it faces numerous threats. To protect the Indian wolf, compensation schemes, community participation, and protection of traditional breeding areas are necessary. [ABSTRACT FROM AUTHOR]

Published
2023
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45. Tracing Modern Human Origins

Author

Harpending, Henry, Eswaran, Vlnayak, Macaulay, Vincent, Hill, Catherine, Achilli, Alessandro, Rengo, Chiara, Clarke, Douglas, Meehan, William, Blackburn, James, Semino, Ornella, Scozzari, Rosaria, Cruciani, Fulvio, Taha, Adi, Shaari, Norazila Kassim, Raja, Joseph Maripa, Ismail, Patimah, Zainuddin, Zafarina, Goodwin, William, Bulbeck, David, Bandelt, Hans-Jürgen, Oppenheimer, Stephen, Torroni, Antonio, Richards, Martin, Thangaraj, Kumarasamy, Chaubey, Gyaneshwer, Kivisild, Toomas, Reddy, Alla G., Singh, Vijay K., Rasalkar, Avinash A., and Singh, Lalji

Published
2005

47. Signatures of high altitude adaptation in Tibeto‐Burman tribes of the Darjeeling Hill Region.

Author

De, Saptaparni, Rai, Divya, Tamang, Shishir, Sherpa, Rinchen Doma, Subba, Soni, Lepcha, Dup Tshering, Govindaraj, Periyasamy, Thangaraj, Kumarasamy, Chaubey, Gyaneshwer, and Tamang, Rakesh

Subjects
DIASTOLIC blood pressure, SYSTOLIC blood pressure, MULTIVARIATE analysis, BODY mass index, ALTITUDES
Abstract

Objectives: The long‐term isolation, endogamy practices, and environmental adaptations have shaped the enormous human diversity in India. The genetic and morphological variations in mainland Indians are well studied. However, the data on the Indian Himalayan populations are scattered. Thus, the present study attempts to understand variations in the selected parameter among four Tibeto‐Burman speaking ethnic tribal populations from the Darjeeling Hill Region (DHR) in the Eastern Himalaya Biodiversity Hotspot region of India. Methods: A total of 178 healthy male individuals (Lepcha 98, Sherpa 31, Bhutia 27, and Tibetans 22) living at an altitudinal range of 1467–2258 m above the sea level were studied for the 10 parameters namely, weight (kg), height (cm), body mass index (BMI) (kg/m2) systolic and diastolic pressure (mm of Hg), pulse rate (per minute), saturation of peripheral oxygen (SPO2) (%), hemoglobin (g/dl), hematocrit (HCT) (%), and blood glucose (mg/dl). The data was statistically analyzed using analysis of variance and multiple linear regression methods. Results: Our analysis revealed comparatively lower hemoglobin and HCT levels, and higher systolic and diastolic blood pressure in the Sherpas followed by the Tibetans. This may be reflecting the persistence of high‐altitude adaptation signatures even in lowlands. Interestingly, the Tibetans differed significantly from other populations in terms of their higher body weight, height, and BMI. Conclusion: Thus, our study showed the persistence of high altitude signatures in Tibetans and Sherpa inhabited the DHR. Additionally, we also observed significant differences in the anthropometric and physiological parameters among the Tibeto‐Burman populations of the DHR. [ABSTRACT FROM AUTHOR]

Published
2023
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48. Genetic Diversity and Spatiotemporal Distribution of SARS-CoV-2 Alpha Variant in India.

Author

Parasar, Jahnavi, Pandey, Rudra Kumar, Patel, Yashvant, Singh, Prajjval Pratap, Srivastava, Anshika, Mishra, Rahul Kumar, Kumar, Bhupendra, Rai, Niraj, Mishra, Vijaya Nath, Shrivastava, Pankaj, Kishor, P. B. Kavi, Suravajhala, Prashanth, Tamang, Rakesh, Pathak, Ajai Kumar, and Chaubey, Gyaneshwer

Subjects
GENETIC variation, SARS-CoV-2, PUBLIC health, PHYLOGENY
Abstract

After the spill to humans, in the evolutionary timeline of SARS-CoV-2, several positively selected variants have emerged. A phylogeographic study on these variants can reveal their spatial and temporal distribution. In December 2020, the alpha variant of the severe acute respiratory syndrome coronavirus (SARS-CoV-2), which has been designated as a variant of concern (VOC) by the WHO, was discovered in the south-eastern United Kingdom (UK). Slowly, it expanded across India, with a considerable number of cases, particularly in North India. This study focuses on determining the prevalence and expansion of the Alpha variants in various parts of India mainly by using phylospatial analysis. The genetic diversity estimation has helped us to understand various evolutionary forces that have shaped the spatial distribution of this variant during its peak. Overall, our study paves the way to understanding the evolution and expansion of a virus variant, which may help to mitigate in the case of any future wave. [ABSTRACT FROM AUTHOR]

Published
2023
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49. Origin and spread of human mitochondrial DNA haplogroup U7

Author

Sahakyan, Hovhannes, Hooshiar Kashani, Baharak, Tamang, Rakesh, Kushniarevich, Alena, Francis, Amirtharaj, Costa, Marta D, Pathak, Ajai Kumar, Khachatryan, Zaruhi, Sharma, Indu, van Oven, Mannis, Parik, Jüri, Hovhannisyan, Hrant, Metspalu, Ene, Pennarun, Erwan, Karmin, Monika, Tamm, Erika, Tambets, Kristiina, Bahmanimehr, Ardeshir, Reisberg, Tuuli, Reidla, Maere, Achilli, Alessandro, Olivieri, Anna, Gandini, Francesca, Perego, Ugo A., Al-Zahery, Nadia, Houshmand, Massoud, Sanati, Mohammad Hossein, Soares, Pedro, Rai, Ekta, Šarac, Jelena, Šarić, Tena, Sharma, Varun, Pereira, Luisa, Fernandes, Veronica, Černý, Viktor, Farjadian, Shirin, Singh, Deepankar Pratap, Azakli, Hülya, Üstek, Duran, Ekomasova (Trofimova), Natalia, Kutuev, Ildus, Litvinov, Sergei, Bermisheva, Marina, Khusnutdinova, Elza K., Rai, Niraj, Singh, Manvendra, Singh, Vijay Kumar, Reddy, Alla G., Tolk, Helle-Viivi, Cvjetan, Svjetlana, Lauc, Lovorka Barac, Rudan, Pavao, Michalodimitrakis, Emmanuel N., Anagnou, Nicholas P., Pappa, Kalliopi I., Golubenko, Maria V., Orekhov, Vladimir, Borinskaya, Svetlana A, Kaldma, Katrin, Schauer, Monica A., Simionescu, Maya, Gusar, Vladislava, Grechanina, Elena, Govindaraj, Periyasamy, Voevoda, Mikhail, Damba, Larissa, Sharma, Swarkar, Singh, Lalji, Semino, Ornella, Behar, Doron M., Yepiskoposyan, Levon, Richards, Martin B., Metspalu, Mait, Kivisild, Toomas, Thangaraj, Kumarasamy, Endicott, Phillip, Chaubey, Gyaneshwer, Torroni, Antonio, and Villems, Richard

Published
2017
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