25 results on '"Chau, C. K."'
Search Results
2. Microstructures of magnesium oxychloride
- Author
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Chau, C. K. and Li, Zongjin
- Published
- 2008
- Full Text
- View/download PDF
3. Screening interval for diabetic retinopathy: a personalised approach (abridged secondary publication).
- Author
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Lian, J., Lam, C. L. K., Thach, T. Q., McGhee, S., Fung, C. S. C., Kwong, A. S. K., Chau, C. K. V., and Chan, J. C. H.
- Published
- 2023
4. Low-temperature magnetothermal conductivity of pyrolytic graphite
- Author
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Chau, C. K. and Lu, S. Y.
- Published
- 1974
- Full Text
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5. Costs and Benefits of Implementing Green Building Economic Incentives: Case Study of a Gross Floor Area Concession Scheme in Hong Kong.
- Author
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Ke Fan, Chan, Edwin H. W., and Chau, C. K.
- Abstract
Economic incentives are widely used to promote green buildings (GB) and consume social resources. However, few studies evaluate the costs and benefits of implementing economic incentives, including hidden costs and benefits. This paper applies cost–benefits analysis (CBA) and transaction cost (TC) theory to systematically evaluate the costs and benefits of implementing the green building economic incentives, with focused study on the Gross Floor Area (GFA) Concession Scheme in Hong Kong. The data of costs and benefits indicate how the GFA Concession Scheme motivates stakeholders and how much it benefits the built environment, which provides a solid foundation for the improvement of the GFA Concession Scheme. Expert interviews were conducted to verify and compliment the new CBA framework and provide empirical evidence for policy-makers and researchers to better understand the allocation of costs and benefits. The results show that the effectiveness of the GFA Concession Scheme is readily justified even if it has caused a lot of extra transaction costs and actual costs. A 10% GFA concession attracts developers to enter the GB market but discourages them to go for a higher level of GB. It is the right time to differentiate the GFA concession to promote a higher level of GB. [ABSTRACT FROM AUTHOR]
- Published
- 2018
- Full Text
- View/download PDF
6. The effects of neighborhood views containing multiple environmental features on road traffic noise perception at dwellings.
- Author
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Leung, T. M., Xu, J. M., Chau, C. K., Tang, S. K., and Pun-Cheng, L. S. C.
- Subjects
TRAFFIC noise ,NEIGHBORHOODS ,NOISE barriers ,NOISE control ,NOISE pollution - Abstract
The importance of non-acoustical factors including the type of visual environment on human noise perception becomes increasingly recognized. In order to reveal the relationships between long-term noise annoyance and different types of neighborhood views, 2033 questionnaire responses were collected for studying the effect of perceptions of different combinations of views of sea, urban river, greenery, and/or noise barrier on the annoyance responses from residents living in high-rise apartments in Hong Kong. The collected responses were employed to formulate a multivariate model to predict the probability of invoking a high annoyance response from residents. Results showed that views of sea, urban river, or greenery could lower the probability, while views of noise barrier could increase the probability. Views of greenery had a stronger noise moderation capability than views of sea or urban river. The presence of an interaction effect between views of water and views of noise barrier exerted a negative influence on the noise annoyance moderation capability. The probability due to exposure to an environment containing views of noise barriers and urban rivers would be even higher than that due to exposure to an environment containing views of noise barriers alone. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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- View/download PDF
7. Potentiometric Study of the Formation of Magnesium Potassium Phosphate Hexahydrate.
- Author
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Chau, C. K., Qiao, Fei, and Li, Zongjin
- Subjects
- *
SCANNING electron microscopes , *TERNARY system , *X-ray diffraction , *POTENTIOMETRY , *MAGNESIUM , *POTASSIUM , *PHOSPHATE minerals - Abstract
The formation process of magnesium potassium phosphate hexahydrate was studied by monitoring the pH development of the MgO-KH2PO4-H2O system. It is found that a typical potentiometric curve goes through several rises and drops, forming two local peaks and two local valleys, before reaching a plateau at pH of approximately 10.5. The characteristic points of the curve are identified and then utilized to distinguish the different reaction stages during the formation of the hexahydrate. By comparing the potentiometric curves of the ternary systems with different molar ratios, and from X-ray diffractometry analysis of the precipitates extracted at different stages, the formation of the hexahydrate most likely proceeds stepwise through two crystalline intermediates, namely MgHPO4·7H2O and Mg2KH(PO4)2·15H2O. The thermal behavior of the formation process of magnesium potassium phosphate hexahydrate, including the formation and transformation among the intermediates and final product, is further verified by thermodynamic calculation. Finally, the morphologies of the different crystalline phases of the ternary system are examined by a scanning electron microscope (SEM). [ABSTRACT FROM AUTHOR]
- Published
- 2012
- Full Text
- View/download PDF
8. Viscoplastic Analysis of Cementitious Extrudates under Squeeze Flow.
- Author
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Chau, C. K., Xiangyu Li, and Zongjin Li
- Subjects
VISCOPLASTICITY ,CEMENT composites ,RHEOLOGY ,MATHEMATICAL optimization ,MATERIAL plasticity - Abstract
A successful extrusion of fiber-reinforced cementitious composites requires a thorough understanding and proper design of the rheological properties of extrudates. The squeeze flow test is regarded as an effective method to evaluate the rheological properties of semi-solid-state fresh extrudates. Based on the strain rates derived from a generalized velocity field, the viscoplastic behavior of cementitious extrudates can be analyzed using the von Mises yield criterion combined with the nonlinear Herschel- Bulkley constitutive relationship. As far as the squeezing force is concerned, the theoretical predictions show good agreement with the experimental measurements. It is found that the bulging phenomenon of a specimen during the squeeze flow process can be depicted by the radial velocity component. Moreover, the velocity field of fresh cementitious extrudates under large plastic deformation is obtained. The present viscoplastic analysis of short fiber-reinforced cementitious extrudates under plastic flow is believed to be a promising mathematical tool toward optimization of formulation for the booming extrusion application. [ABSTRACT FROM AUTHOR]
- Published
- 2009
- Full Text
- View/download PDF
9. Cosorption Processes of Triethylene Glycol in a Packed-Bed Liquid Desiccant Dehumidifier.
- Author
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Chau, C. K. and Worek, W. M.
- Subjects
- *
TOLUENE , *AROMATIC compounds , *ETHYLENE glycol , *MASS transfer , *WATER vapor transport , *ATMOSPHERIC thermodynamics - Abstract
The cosorption characteristics of water and toluene vapors in various concentrations of triethylene glycol (TEG) solution flowing through a packed-bed dehumidifier are investigated in this paper. A multi-component model was constructed using the reported equilibrium relationships of toluene and water vapors in TEG solutions together with the Krishna-Standart multi-component mass transfer correlation. The effects of liquid-to-air ratios, TEG inlet temperatures, air inlet temperatures were reported on the moisture and toluene removal rate as well as the moisture and toluene removal efficiency of the packed dehumidifier. Running the packed dehumidifier in a higher liquid-to-gas flow ratio generally increased the removal rates and efficiencies of both water vapor and toluene vapor from the airstream. Increasing inlet temperatures of the TEG solution led to a decrease in the removal rate of water vapor when running the packed dehumidifier at a high liquid-to-gas flow ratio. However, there was no significant change in the toluene vapor removal rate or toluene removal efficiency when the flow rate of the inlet TEG solution was increased. [ABSTRACT FROM AUTHOR]
- Published
- 2009
- Full Text
- View/download PDF
10. Microstructures of magnesium oxychloride Sorel cement.
- Author
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Chau, C. K. and Li, Z.
- Subjects
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MICROSTRUCTURE , *CEMENT , *CONSTRUCTION materials , *CRYSTALS , *CRYSTALLOGRAPHY - Abstract
The article examines the microstructures of magnesium oxychloride Sorel cement. The variation in strength among Sorel cement with different mixture designs is attributed to the different phase compositions and the corresponding distinct microstructures. Its crystalline phases are needle-shaped crystals, bundled in different forms, with a granular surface of nano-sized grains. The different crystalline phases of the cement's microstructure were identified through elemental composition analysis.
- Published
- 2008
- Full Text
- View/download PDF
11. Reactivity and Function of Magnesium Oxide in Sorel Cement.
- Author
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Li, Zongjin and Chau, C. K.
- Subjects
- *
POWDERS , *OXYCHLORIDES , *CRYSTALS , *CHLORIDES , *X-ray diffraction , *PORTLAND cement - Abstract
The reactivity, or rate of consumption, of magnesium oxide (MgO) powder used in forming magnesium oxychloride (MOC) cement is largely affected by its thermal history and particle size. That, in turn, influences both reaction rate and properties of the reaction products of MOC cement. It is believed that the traditional measurements of properties of MgO powder itself are not able to reflect the actual consumption rate of MgO during chemical reaction, which is the key information needed for the appropriate proportions of starting materials to ensure the formation of Phase 5 crystals for better strength and physical properties. The experimental results show that X-ray diffractograms and phase diagram of a ternary MOC system can be utilized to evaluate the reactivity of MgO, and to optimize the formulation of MOC cement as well. Consequently, the apparent molar ratios of MgO over magnesium chloride (MgCl2) are adopted and recommended. The equivalent weight ratios between MgO and MgCl2 are also given for the convenience of normal applications. [ABSTRACT FROM AUTHOR]
- Published
- 2008
- Full Text
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12. Accelerated Assessment and Fuzzy Evaluation of Concrete Durability.
- Author
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Zongjin Li, Chau, C. K., and Xiangming Zhou
- Subjects
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CONCRETE , *BUILDING material durability , *CONCRETE construction , *FEEDBACK control systems , *PERMEABILITY , *FUZZY sets - Abstract
Accelerated durability assessment is one of the promising ways to provide a sound basis for service life prediction of concrete. To follow the rapid pace of research in modern concrete technology, an effective accelerated assessment system for concrete durability with automatic control and consistent working performance is highly desired. In this paper, the general concepts and ways of implementing computerized feedback control of a multipurpose accelerated concrete durability test system are first presented and applied to frost-resistant (one of the main durability factors of concrete structures in cold regions) assessment of different concretes. The experimental investigations showed that the newly developed automatic feedback controlled system was reliable and had a promising future for the accelerated durability assessment of concretes. Second, based on the premise that the deterioration mechanisms and the surrounding aggressive environment of the concrete under consideration cannot be precisely described by classical logic, it is believed that durability assessment of concrete is indeed a decision-making process and belongs to the fuzzy logic field. Following this line of thought, a general framework of synthetic concrete durability evaluation was developed by combining the principles of various individual accelerated durability tests, such as frost resistance, water permeability, crack width, and carbonation penetration and concepts of fuzzy logic. The working examples showed that the fuzzy synthetic evaluation developed agreed well with the experimental results for concrete durability investigated. [ABSTRACT FROM AUTHOR]
- Published
- 2005
- Full Text
- View/download PDF
13. Effects of the natural polymer-based durability-enhancing admixture on the frost resistance of concrete.
- Author
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Li, Z., Li, F., and Chau, C. K.
- Published
- 2001
- Full Text
- View/download PDF
14. Towards a successful voluntary building environmental assessment scheme.
- Author
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Chau, C. K., Lee, W. L., Yik, F. W. H., and Burnett, J.
- Subjects
ARCHITECTURAL firms ,BUILDINGS ,ENVIRONMENTAL impact analysis ,VOLUNTEER workers in urban planning ,ECONOMIC development & the environment ,ENVIRONMENTAL protection ,ENVIRONMENTAL monitoring ,ENVIRONMENTAL responsibility ,ENVIRONMENTAL engineering - Abstract
Voluntary building assessment schemes have emerged worldwide to help assess the environmental performance of buildings. As building environmental assessment is a rapidly evolving field, the scope and details of such assessment schemes are continuously undergoing updating and refinement. Substantial efforts have been devoted to the design and improvement of the assessment schemes to make them capable of defining an objective building profile. Although most of the existing schemes are voluntary, many fail to encourage participation of the building investors and designers. In order to widen acceptance, the design of the scheme should be oriented towards the manner in which investors make decisions. This paper provides an overview of the vital elements and changes needed, so as to make a voluntary building environmental assessment scheme more attractive and successful, and will include reforms not only in the scope and the credit weighting philosophy but also in its nature. [ABSTRACT FROM AUTHOR]
- Published
- 2000
- Full Text
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15. A decision support tool for evaluating the air quality and wind comfort induced by different opening configurations for buildings in canyons.
- Author
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Fan M, Chau CK, Chan EHW, and Jia J
- Abstract
This study formulated a new index for evaluating both the air quality and wind comfort induced by building openings at the pedestrian level of street canyons. The air pollutant concentrations and wind velocities induced by building openings were predicted by a series of CFD simulations using ANSYS Fluent software based on standard k-ɛ model. The types of opening configurations investigated inside isolated and non-isolated canyons included separations, voids and permeable elements. It was found that openings with permeability values of 10% were adequate for improving the air quality and wind comfort conditions for pedestrians after considering the reduction in development floor areas. Openings were effective in improving the air quality in isolated canyons and different types of opening configurations were suggested for different street aspect ratios. On the contrary, openings were not always found effective for non-isolated canyons if there were pollutant sources in adjacent street canyons. As such, it would also be recommended introducing openings to adjacent canyons along with openings to the target canyons. The formulated index can help city planners and building designers to strike an optimal balance between air quality and wind comfort for pedestrians when designing and planning buildings inside urban streets and thus promoting urban environmental sustainability., (Copyright © 2016 Elsevier B.V. All rights reserved.)
- Published
- 2017
- Full Text
- View/download PDF
16. Environmental management system vs green specifications: how do they complement each other in the construction industry?
- Author
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Lam PT, Chan EH, Chau CK, Poon CS, and Chun KP
- Subjects
- Resource Allocation, Conservation of Natural Resources, Industry
- Abstract
Environmental Management System (EMS) has been one of the important tools for sustainable construction for around two decades. However, many issues concerning sustainable development have not been properly addressed, and there is a need for the introduction of green specifications to advance green performance in construction through contract management. This paper defines green specifications, identifies the reasons for adopting green specifications and highlights the environmental issues that may not be addressed by solely adopting EMS. It also presents the results of a recent survey of practitioners concerning their opinions towards green specifications and possible impacts arising from their adoption. From the results of the survey, a framework for developing green specifications is deemed valuable for the cities striving for sustainability. Interestingly, the level of acceptable changes brought about by green specifications as perceived by different industry stakeholders is found to be unrelated to whether they were from organizations implementing EMS or not., (Copyright © 2010 Elsevier Ltd. All rights reserved.)
- Published
- 2011
- Full Text
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17. Can surrounding greenery reduce noise annoyance at home?
- Author
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Li HN, Chau CK, and Tang SK
- Subjects
- Adult, Female, Housing, Humans, Male, Middle Aged, Environmental Restoration and Remediation, Irritable Mood, Noise prevention & control, Perception, Plants
- Abstract
Annoyance has been identified as the most important psychological impact arisen from noise. Besides socioeconomic status, residing neighborhood characteristics such as greenery has been shown to be able to reduce noise annoyance. To study the effects of these potential annoyance modifiers, nine hundred and ninety-two responses were collected through face-to-face interviews via questionnaire surveys. Among them, six-hundred and eighty-eight responses were collected together with adequate dwelling information which enabled a more accurate prediction of home noise levels. All these data were analyzed using an ordered logit model. Results indicate that greenery perception exerts considerable influence on noise annoyance rated at home. Wetland parks and garden parks are shown to be able to reduce noise annoyance to a greater degree than grassy hills. And the effects of the perceived amount of greenery on noise annoyance reduction at home differ according to the setting of greenery to which participant perceived from individual home., (Copyright 2010 Elsevier B.V. All rights reserved.)
- Published
- 2010
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- View/download PDF
18. Factors affecting the implementation of green specifications in construction.
- Author
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Lam PT, Chan EH, Poon CS, Chau CK, and Chun KP
- Subjects
- Cross-Sectional Studies, Data Collection, Hong Kong, Industry standards, Statistics, Nonparametric, Conservation of Natural Resources, Construction Materials
- Abstract
Green specifications constitute one of the important elements in green construction. New sustainability requirements and changing priorities in construction management have spurred the emerging green specifications to a faster pace of development. A cross-sectional survey has been conducted in Hong Kong in 2007 to identify principal factors leading to the success of preparing green specifications. Based on extensive construction management literature, 20 variables concerning sustainable construction were summarized. Using the Mann-Whitney U-test, the subtle differences between stakeholders in specifying construction work have been detected even with the high consistency of the responses among the groups. Moreover, five independent factors for successful specification of green construction have been categorized by factor analysis. They are related to (1) green technology and techniques, (2) reliability and quality of specification, (3) leadership and responsibility, (4) stakeholder involvement, and (5) guide and benchmarking systems. Whilst the first and fourth factors are generally more important, different stakeholder groups have different emphases. The results of the survey have been validated against established principles., (2009 Elsevier Ltd. All rights reserved.)
- Published
- 2010
- Full Text
- View/download PDF
19. Valuing the health benefits of improving indoor air quality in residences.
- Author
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Chau CK, Hui WK, and Tse MS
- Subjects
- Adult, Aged, Air Conditioning, Air Pollution, Indoor prevention & control, Health Status, Hong Kong, Humans, Middle Aged, Models, Theoretical, Air Pollutants analysis, Air Pollution, Indoor analysis, Health Behavior, Housing, Particulate Matter analysis
- Abstract
Unlike commercial premises, the indoor air quality of residences is more dynamic, uncontrolled, and prone to human behavioral changes. In consequence, measuring the health benefit gains derived from improving indoor air quality in residences is more complicated. To overcome this, a human thermal comfort model was first integrated with indoor microenvironment models, and subsequently linked with appropriate concentration-response and economic data for estimating the economic benefit gains derived from improving indoor air quality in residences for an adult and an elderly person. In this study, the development of the model is illustrated by using a typical residential apartment locating at the worst air quality neighborhood in Hong Kong and the daily weather profiles between 2002 and 2006. Three types of personal intervention measures were examined in the study: (i) using air cleaner in residence, (ii) changing time spent in residence, and (iii) relocating to a better air quality neighborhood. Our results revealed that employing air cleaners with windows closed in residence throughout the entire year was the most beneficial measure as it could provide the greatest annual health benefit gains. It would give a maximum of HK$2072 in 5-year cumulative benefit gain for an adult and HK$1700 for an elderly person. Employing air cleaners with windows closed in only cool season (October through March) could give the highest marginal return per dollar spent. The benefit gains would become smaller when windows were opened to a greater extent. By contrast, relocating to a better air quality neighborhood and changing the time spent in residence did not appeal to be beneficial intervention measures.
- Published
- 2008
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- View/download PDF
20. Evaluation of health benefits for improving indoor air quality in workplace.
- Author
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Chau CK, Hui WK, and Tse MS
- Subjects
- Air Pollution, Indoor, Hong Kong epidemiology, Humans, Mortality, Occupational Exposure prevention & control, Patient Admission statistics & numerical data, Air standards, Workplace
- Abstract
In contrast to a majority of reported damage-cost literature being focused on outdoor pollution, this paper describes the development of a protocol that links population exposure data with reported epidemiological concentration-response coefficients. A change in indoor particulate level is expressed as a change in total exposure levels, which is then linked with a corresponding change in ambient particulate concentrations before evaluating the associated health benefits. In this study, the development of protocol is illustrated by using a typical office building environment and daily time activity patterns of office occupants in Hong Kong. Our results indicate that some benefit gains for the owners-employers and the society would be anticipated if certain filter set configurations had been adopted. However, the amount of benefit gains for the owners-employers is shown to be increased with the average salary level of employees and the duration of their stay in offices.
- Published
- 2007
- Full Text
- View/download PDF
21. Assessing the benefit and cost for a voluntary indoor air quality certification scheme in Hong Kong.
- Author
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Tse MS, Chau CK, and Lee WL
- Subjects
- Cost-Benefit Analysis, Hong Kong, Humans, Ownership, Public Policy, Ventilation, Volunteers, Air Pollution, Indoor economics, Air Pollution, Indoor prevention & control, Certification, Guideline Adherence, Public Sector
- Abstract
A voluntary indoor air quality certification scheme has been proposed in Hong Kong for assessing and evaluating the indoor air quality level in a variety of public places like offices, restaurants and pubs. The scheme intends to promote the public well being, however, its technical and financial practicality has led to serious discussions among the government officials, practitioners and premises owners. Accordingly, this study intends to develop a protocol for examining its financial viability by linking the appropriate dose-response and economic data with the results from indoor micro-environment models. The financial viability of the scheme is evaluated by examining the cost and benefit associated with compliance on the different prescribed indoor particulate (PM10) levels. According to our analysis, the indoor action level of 180 microg/m3 as 8-h mean (with the objective of protecting the health of general public) does not require office owners to improve beyond the base setting. Nevertheless, owners should consider altering the base settings in their air conditioning systems so as to secure more benefit on every dollar they spent. On the contrary, the 20 microg/m3 level as 8-h mean (with the objective of providing comfort) is not considered to be financially viable for office owners as they will incur financial loss on compliance. Subsequent sensitivity analysis indicates that the total net benefit derived have a great dependency on the value-of-life estimates used. If conservative health estimates are adopted, the optimum level determined to be beneficial to both owners and the society will be 55 microg/m3, which can be obtained by operating the air conditioning system with a ventilation rate of 10 l/s, primary filters of 80-85% efficiency and secondary filters efficiency of 60-65% arrestance. This information should be extremely valuable for government officials and policy makers in assessing the financial viability of the voluntary indoor assessment scheme.
- Published
- 2004
- Full Text
- View/download PDF
22. Review of children with severe trauma or thermal injury requiring intensive care in a Hong Kong hospital: retrospective study.
- Author
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Ng DK, Cherk SW, Yu WL, Lau MY, Ho JC, and Chau CK
- Subjects
- Accidental Falls statistics & numerical data, Accidents, Traffic statistics & numerical data, Child, Child, Preschool, Female, Hong Kong epidemiology, Humans, Infant, Male, Retrospective Studies, Burns epidemiology, Intensive Care Units, Pediatric statistics & numerical data, Wounds and Injuries epidemiology
- Abstract
Objective: To study the injury pattern of children admitted for management of severe trauma or thermal injury., Design: Retrospective review., Setting: Paediatric intensive care unit of a regional hospital, Hong Kong., Patients: Twenty-eight children were admitted under this category from July 1996 to December 1999., Main Outcome Measures: Mechanisms, severity, and circumstances of injury., Results: Road traffic accident was the most common cause of admission, followed by thermal injury, accidental fall, and non-accidental injury. However, children with non-accidental injury were admitted in a significantly more severe condition, as measured by the paediatric risk of mortality score, than those admitted for the other three reasons. Non-accidental injury was also associated with significantly higher morbidity and mortality than the other causes of admission., Conclusions: During the 42-month study period, trauma and thermal injury accounted for 7% of all admissions to the paediatric intensive care unit. Road traffic accident was the most common reason, while non-accidental injury accounted for the most serious injury. Detailed analysis of these cases identified certain preventable risk factors.
- Published
- 2002
23. Estimating the total exposure to air pollutants for different population age groups in Hong Kong.
- Author
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Chau CK, Tu EY, Chan DW, and Burnett J
- Subjects
- Adolescent, Adult, Age Factors, Aged, Child, Child, Preschool, Dust, Female, Forecasting, Hong Kong, Humans, Infant, Infant, Newborn, Male, Middle Aged, Particle Size, Vehicle Emissions, Air Pollutants analysis, Carbon Monoxide analysis, Environmental Exposure, Nitrogen Dioxide analysis
- Abstract
Given that Hong Kong is one of the most densely populated cities in the world, the exposure of the Hong Kong people is one of the interesting research areas. In this study, an indirect approach was used to estimate the exposure to nitrogen dioxide (NO2), respiratory dust (PM10) and carbon monoxide (CO) pollutants experienced by different age groups of people in Hong Kong. The average concentrations of the 20 major microenvironments obtained from our measurement survey data, together with the people activity pattern data obtained from 7-day recall questionnaires, were used to predict frequency distributions to exposure assessment. Our results showed that Hong Kong people spent more than 86% of their time indoors. Homes were shown to be the one of the major exposure sites to NO2, CO and PM10 for all age groups. Our results also indicate that the 24-h NO2 exposure for individuals, irrespective of age, spending more than 2 h in commuting daily, was observed to be exceeding the 24-h NO2 exposure standards. This study was one of the pioneering studies with valuable contribution for modeling the estimates of exposures to NO2, PM10 and CO of different age groups in Hong Kong.
- Published
- 2002
- Full Text
- View/download PDF
24. Improved sensitivity in blue-membrane bacteriorhodopsin films.
- Author
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Millerd JE, Rohrbacher A, Brock NJ, Chau CK, Smith P, and Needleman R
- Abstract
We show that D85N/V49A, a mutant bacteriorhodopsin in which two residues, aspartate (D) at position 85 and valine (V) at position 49, have been replaced with asparagine (N) and alanine (A), respectively, has significantly improved optical properties compared with other forms of blue-membrane Bacteriorhodopsin. Absorption studies of the mutant in gels show that it forms the P(490) state at light levels that are comparable with M-state formation in wild-type films. Theoretical calculations based on Kramers-Kronig transformation of light-induced absorption data predict that the refractive index is three times larger than that of mutant D85N. Holographic measurements performed on gelatin-based films confirm that the sensitivity is improved by a factor of 50 over that of D85N.
- Published
- 1999
- Full Text
- View/download PDF
25. Goosecoid-like sequences and the smallest region of deletion overlap in DiGeorge and velocardiofacial syndromes.
- Author
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Pragliola A, Jurecic V, Chau CK, Philip N, and Baldini A
- Subjects
- Animals, Chromosomes, Human, Pair 22 ultrastructure, Exons genetics, Goosecoid Protein, Humans, In Situ Hybridization, Fluorescence, Mice, Syndrome, Abnormalities, Multiple genetics, Chromosomes, Human, Pair 22 genetics, Cleft Palate genetics, DNA-Binding Proteins genetics, DiGeorge Syndrome genetics, Face abnormalities, Heart Defects, Congenital genetics, Homeodomain Proteins, Repressor Proteins, Sequence Deletion, Transcription Factors
- Published
- 1997
- Full Text
- View/download PDF
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