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Byline: Marie. Manipadam, Suresh. Bhagat, Ganesh. Gopalakrishnan, Nitin. Kekre, Ninan. Chacko, Samuel. Prasanna Aims: There are few studies on the pathology of warty carcinoma (WC) of the penis and these [...]

Byline: Gaurav. Gupta, Mukha. Paul, Santosh. Kumar, Antony. Devasia, N. Mahendri, Prasanna. Samuel, Nitin. Kekre, Ninan. Chacko Objective: To identify the differences in urinary profile of a stone former and [...]

Byline: Sriram. Krishnamoorthy, Ganesh. Gopalakrishnan, Nitin. Kekre, Ninan. Chacko, Shyam. Keshava, George. John Sir, We appreciate the reader's [sup][1] interest in our article on Transplant Renal Artery Stenosis (TRAS). [sup][2] [...]

Byline: Francis. Katumalla, Antony. Devasia, Ramani. Kumar, Santosh. Kumar, Ninan. Chacko, Nitin. Kekre Aim : To assess the need of a second transurethral resection (TUR) in select T1G3 bladder tumor [...]

Byline: Shanmugasundaram. Rajaian, Santosh. Kumar, Ganesh. Gopalakrishnan, Ninan. Chacko, Antony. Devasia, Nitin. Kekre Purpose : To evaluate the outcome of shock wave lithotripsy (SWL) as monotherapy for solitary renal stones [...]

Byline: Sriram. Krishnamoorthy, Ganesh. Gopalakrishnan, Nitin. Kekre, Ninan. Chacko, Shyam. Keshava, George. John Purpose: To assess the effects of transplant renal artery stenosis (TRAS) on blood pressure, renal function, and [...]

Byline: Gaurav. Gupta, Samiran. Adhikary, Santosh. Kumar, Ninan. Chacko, Nitin. Kekre, Ganesh. Gopalakrishnan Objectives: To study the differences in the clinico-pathological features of incidental and symptomatic T1 renal cell carcinoma [...]

Dear Sir, We have read the comments by Kumar R on our article. We regret missing the communication published in the correspondence section of NMJI titled 'Priapism following oral sildenafil [...]

Aim: To analyze the impact of variation in CITs due to delays caused by staffing problems and theater availability, on graft kidney function. Methods: The authors retrospectively looked at all deceased donor transplants wherein both kidneys from the same donor were transplanted in this institution, with the aim of studying the kidney pair with all donor factors being constant except the cold ischemia time. There were 15 donors and 30 recipients. The only varying donor factor was a difference in Cold Ischemia Times arising out of delays in surgery. The authors considered only transplant done in one institution to remove the possibility of the "center effect" and to keep the intra-pair parameters as similar as possible. The index kidney (K1) was the one with the longer CIT whereas its "mate" with the shorter CIT was K2. Apart from the demographics the authors looked at the causes of ESRD in recipients, the absolute Cold Ischemia Times, the differential Cold ischemia times, differences in urine output during the first 24 hours, episodes of rejection, creatinine trends and the need for dependence among the two groups. Eighty percent of the donors and 73.3% recipients were male. Diabetes Mellitus was the most common known cause of ESRD (n=6). The cause was unknown in 16 patients. While the mean CIT in the index kidneys (K1) was 862 minutes it was 683 mins in the mate (K2). The mean differential CIT was 137 minutes. The mean output in the K1 group was 2770 mls in the first 24 hours as compared to 4084 mls in the mate (K2) kidneys. Rejection episodes were not significantly different in both the groups. The need for dialysis was greater in the K2 group showing recipient factors were more important in determining dialysis dependence in the early transplant period. The mean creatinine at first year was 1.8 and 1.4 in K1 and K2 respectively. There was no significant difference in graft loss or survival between both groups. Conclusion: The authors concluded that though differences in Cold Ischemia time due to above-mentioned reasons did have an impact on the immediate graft function, it did not seem to affect the short-term graft function or patient survival. [ABSTRACT FROM AUTHOR]

Aim: To evaluate the outcome of using potential donor kidneys with asymptomatic calculi detected during screening with specific reference to the pre operative work up and the management of the calculus prior to, during and after transplantation. Materials and Methods: Ten live related donors, detected to have a single incidentally detected calculus, during their routine work up, were accepted for transplantation from 2002 to 2006. There was no biochemical evidence of metabolic abnormality or history of stone disease. Four donor kidneys underwent elective shock wave lithotripsy and in one, nephrolithotomy was carried out under ultrasound control after perfusion. The others were transplanted with the calculus in-situ. Ureteric reimplantation was carried out over a double J stent. Results: One calculus was passed out soon after stent removal. The follow up imaging showed the calculus in only one. In the others, the stone could not be visualized after stent removal. The maximum follow up was 60 months for donor and recipients. The graft function has remained normal in eight and no donor has developed recurrence of calculus. Conclusions: Voluntary kidney donors with a single calculus incidentally detected on routine evaluation, form a unique group and can be accepted for transplantation in highly selected cases. Careful follow-up of the donor and recipient is essential with early intervention if necessary. [ABSTRACT FROM AUTHOR]

A response by Samiran D. Adhikary, M. Sinha and Ninan Chacko to a letter to the editor about their article on sildenafil induced priapism is presented.