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1,056 results on '"Celik, S."'

3. Refugee Education in Turkey: Barriers and Suggested Solutions

Author

Celik, S., Kardas Isler, N., and Saka, D.

Abstract

Education is among the areas most affected by immigration. Addressing refugee children's schooling is an important contribution to the refugee crises, which span the world with far-reaching socio-economic effect. This study unpacks the challenges that refugee children, mainly from Syria, face in integrating into primary and secondary public schools in Turkey. It also proposes some tentative resolutions, drawing from the experiences of refugee parents, teachers, and headteachers. Within the current study, data were collected by means of fishbone analysis and semi-structured interviews with the participation of teachers, school headteachers, and refugee parents. The study draws from the theories of refugee education and confirms students' barriers in schooling with regard to psychosocial factors, cultural adaptation, language learning, systemic barriers, and family relations. Some further implications were elicited from the data and are discussed in line with the existing research.

Published
2023
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6. GnRH antagonist protocol with hCG triggering ameliorates fertilization defect caused by failure of cumulus cell pentraxin-3 expression in unilateral endometriomas.

Author

GUNGOR, N. D., CELIK, O., ERSAHIN, A., CELIK, N., KOBANER, M., YARDIM, M., DALKILIC, S., MELIL, S., CIL, K., CELIK, S., and AKKOC, R.

Abstract

OBJECTIVE: The aim of the study was to determine the expression pattern of long pentraxin 3 (PTX3) mRNA in cumulus cells (CCs) isolated from metaphase II oocytes of women with unilateral endometrioma undergoing controlled ovarian stimulation using a gonadotropin-releasing hormone antagonist (GnRHa) protocol. PATIENTS AND METHODS: A total of 60 CC samples, 30 from the affected ovary and 30 from the contralateral ovary, were collected from 12 patients with unilateral endometrioma who underwent flexible GnRHa protocol with recombinant human chorionic gonadotropin (rhCG) trigger. Thirty CC samples collected from the left ovary of 12 women with male factor infertility were used as external controls. Long PTX3 mRNA expression in each group was analyzed by real-time polymerase chain reaction (RT-PCR). Relative gene expression (fold-change) was calculated according to the 2-ΔΔCt equation. Fertilization rates after intracytoplasmic sperm injection (ICSI) were recorded for each group. RESULTS: CC-PTX3 mRNA expression in the unilateral endometrioma group was significantly lower than the mRNA expression of the disease-free ovary (0.90±0.01 vs. 0.25±0.02, p<0.01). CC-PTX3 mRNA expression of MII oocytes of the disease-free ovary was found to be similar to the control group (1.02±0.03 vs. 0.90±0.01, p=0.107). A significant 3.6-fold downregulation was observed in the CC-PTX3 mRNA expression of the endometrioma group compared to the CC-PTX3 mRNA expression in the contralateral ovary. CCPTX3 mRNA expression in the endometrioma group was downregulated 4.08-fold compared to the CC-PTX3 mRNA expression of the control group (1.02±0.03 vs. 0.25±0.02, p<0.001). The cumulus morphologies of the endometrioma group with low CC-PTX3 expression and the groups with normal CC-PTX3 levels were similar. Fertilization rates of the endometrioma group were similar to the contralateral ovary and control groups. CONCLUSIONS: Unilateral endometrioma reduces CC-PTX3 expression but does not affect disease-free ovaries. The GnRHa protocol improved the fertilization rates, suggesting that failed CCPTX3 expression is an in vivo pathology. [ABSTRACT FROM AUTHOR]

Published
2024

8. Cerebral Palsy in Very Preterm Infants: A Nine-Year Prospective Study in a French Population-Based Tertiary Center

Author

Lévêque, C., Simenel, J.-L., Pauthier, S., Levavasseur, C., Pop, I., Grancher, N., Lefebure, A., Vittecoq, C., Dabbagh, D., Machevin, E., Levy, M., Taleb, F., Lahrach, H., Rhali, H., Richet, B., Delaunay, F., Bruel, H., Selim, A., Jaffray, M., Durand-Réville, M., Sarreau, C., Celik, S., Le Digabel, J.-F., Stoller, J., Muszynski, H., Rouha, M., Verspyck, E., Chadi, A., Lardennois, C., Chollat, Clément, Bertrand, Emmanuelle, Petit-Ledo, Alice, de Vansay, Caroline, Voisin, Caroline, Dabaj, Ivana, Gillibert, André, and Marret, Stéphane

Published
2021
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31. Treatment and outcomes of patients with metastatic spinal cord compression: a double-center study.

Author

AYCAN, A., EREN, B., TAS, A., CELIK, S., KARAGOZ GUZEY, F., KUYUMCU, F., AKYOL, M. E., SAGLAM, E., and AYCAN, N.

Abstract

OBJECTIVE: Spinal metastases may only affect the bone tissue and result in spinal instability or may additionally result in epidural compression, leading to neurological deficits. Surgery has emerged as a popular method in treating metastatic epidural spinal cord compression (MESCC) due to the advances in surgical techniques and instrumentation. In this study, we evaluated patients with MESCC regarding neurological status, pain status, and survival rates, and presented our experience managing MESCC. PATIENTS AND METHODS: Clinical and radiographic records of 53 patients diagnosed with MESCC between January 2011 and March 2017 were retrospectively evaluated. The study included patients with a pathological diagnosis of primary cancer, those who complained of spinal metastasis, and those who had indications of MESCC on Magnetic Resonance Imaging (MRI). Bone structure and spinal stability were evaluated using assessed Computed Tomography (CT), and metastatic spread was considered using assessed Positron Emission Tomography (PET) in suitable cases. For each patient, the presence of a tumor compressing the spinal cord, age, gender, preoperative, and postoperative American Spinal Injury Association scores (ASIA), Tokuhashi prognostic score (TPS), affected spinal segment, pathological diagnosis, preoperative, and postoperative Visual Analog Scale (VAS), the status of spinal stability, follow-up period, and complications were evaluated. RESULTS: Forty-five patients (82.2% of them were women) underwent surgery with a mean age of 58.29 ± 15.14 years. The most frequent type of primary tumor was multiple myeloma (33.9%), followed by lung (24.6%), gastric (7.5%), and prostate (5.7%). The most common site of lowed by lumbar (24.5%), multiple (24.5%), and cervical (5.7%). The analysis indicated that a significant difference was found between the survival rates of the TPS categories. CONCLUSIONS: Common symptoms of MESCC include spinal pain and neurological deficit below the level of the injury. Prompt surgical treatment followed by oncological treatment leads to significant neurological recovery, more prolonged survival, pain relief, and improved quality of life in patients with a short survival time. Oncological treatments, including radiotherapy (RT), should be recommended after surgical treatment. [ABSTRACT FROM AUTHOR]

Published
2023

36. Does intestinal obstruction influence hypo-albuminemia: assessment of the physio-pathogenesis of protein-losing enteropathy with literature review.

Author

BAKKALOGLU, O. K., BAVUNOGLU, I., ASLAN, S., ESKAZAN, T., CELIK, S., KEPIL, N., HATEMI, I., ERZIN, Y., and CELIK, A. F.

Abstract

BACKGROUND: Non-steroidal anti-inflammatory drug (NSAID) use may cause diaphragm-like lesions in the bowel. Although NSAID-enteropathy is among the causes of protein-losing enteropathy (PLE), intractable hypoalbuminemia is rare. CASE REPORT: Here, we discuss a case of NSAID-enteropathy with a diaphragm-like disease that presented with Protein Losing Enteropathy (PLE) rather than obstruction. The hypoalbuminemia recovered immediately after resection of the obstructive segment, despite ongoing annular ulcerations in the early postoperative period. Thus, it was not clear whether obstructive mechanisms influenced resistant hypoalbuminemia besides the ulcers. We also reviewed the English-written literature for “diaphragm-type lesion, NSAID-enteropathy, obstruction, and protein-losing enteropathy”. We noted that the role of obstruction in the pathophysiology of PLE was not clear. CONCLUSIONS: As our case and a couple of cases reported in literature, slow-onset obstructive pathology seems to contribute to well-known factors: inflammatory response, exudation, tight-junction dysfunction, and increase in permeability in the physiopathology of NSAID-induced PLE. Factors such as distention-induced low-flow ischemia and reperfusion, cholecystectomy-related continuous bile flow, bacterial overgrowth-related bile deconjugation and concomitant inflammation are among other potential influencers. The possible role of a slow-onset obstructive pathology in the physiopathology of NSAID-induced and other PLE needs to be further elucidated. [ABSTRACT FROM AUTHOR]

Published
2023

39. Topic: Inguinal Hernia — Primary inguinal hernia, state of the art in the different socio economic reality

Author

Lubrano, T., Vidotto, C., Falcone, A., Grasso, L., G, F., Morino, M., Techapongsatorn, S., Tansawet, Amarit, Lerdsirisopon, Sopon, Kasetsermwiriya, Wisit, Srimontayamas, Satit, Loapeamthong, Ched-U-Sa, Teawprasert, Piya, Takehara, H., Nishihara, M., Kuniyoshi, F., Miyahira, T., Hanashiro, N., Takushi, Y., Aka, H., Nakagawa, H., Shiraishi, M., Okushima, N., Soler, M., Oyama, R., Chihara, N., Suzuki, H., Watanabe, M., Nakata, R., Uchida, E., Mitura, K., Koziel, S., Pasierbek, M., Maietta, P., Iannace, C., Lee, H., Cho, H., Jovanovic, S., Pejcic, V., Trenkic, M., Filipovic, N., Pavlovic, A., Jovanovc, B., Hemberg, A., Nordin, P., Holmberg, H., De Rosa, A., Meyer, A., Seabra, A. P., Sorge, A., Hack, J., Soares, L. A. N. G., Chalub, S. R. S., Malcher, R., Kingsnorth, A., Dabic, D., Maric, B., Perunicic, V., Kocaay, A. F., Eker, T., Celik, S. U., Akyol, C., Cakmak, A., Contino, E., Molinari, P., Lanza, C., Binda, M., Livraghi, L., Farassino, L., Cocozza, E., Crespi, A., Ambrosoli, A., Zhao, Y., Li, J. W., and Zheng, M. H.

Published
2015
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40. Topic: Abdominal Wall Hernia — Abdominal wall closure

Author

Woeste, G., Juratli, M. A., Habbe, N., Hannes, S., El Youzouri, H., Bechstein, W. O., Trombetta, F., Moscato, R., Ciamporcero, T., Ghiglione, F., Morino, M., Tahir, S., Baldjiev, T., Goshev, G., Pachoov, N., Eftimov, E., Kovachevski, S., Smirnoff, A., Roth, J. S., Wennergren, J., Plymale, M. A., Zachem, A., Davenport, D. L., Mangiante, G., Passeri, V., deManzoni, G., Kaufmann, R., Jairam, A. P., Mulder, I. M., Wu, Z., Verhelst, J., Vennix, S., Giessen, L. J. X., Jeekel, J., Lange, J. F., Di Cerbo, F., Ikhlawi, K., Baladov, M., Agha, A., Iesalnieks, I., Franklin, M., Hernandez, M., Glass, J., Glover, M., Gruber-Blum, S., Fortelny, R., May, C., Glaser, K., Redl, H., Petter-Puchner, A., Grossi, J., Cavazzola, L. T., Tezza, S. L. T., Nery, L. A., Zortea, J., Roll, S., Gorganchian, F., Santa Maria, V., Zuvela, M., Galun, D., Petrovic, J., Micev, M., Palibrk, I., Bidzic, N., Colozzi, S., Clementi, M., Cianca, G., Giuliani, A., Carlei, F., Schietroma, M., Amicucci, G., Chung, M., Cerasani, N., Meyer, J., Bulian, D. R., Heiss, M. M., Kocaay, A. F., Eker, T., Celik, S. U., Akyol, C., and Cakmak, A.

Published
2015
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