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Your search keyword '"Buxton, Jane"' showing total 954 results
Start Over Author "Buxton, Jane" Publication Type Academic Journals
954 results on '"Buxton, Jane"'

1. Management of Amphetamine and Methamphetamine Use Disorders: A Systematic Review and Network Meta-analysis of Randomized Trials

Author

Khalili, Malahat, Sadeghirad, Behnam, Bach, Paxton, Crabtree, Alexis, Javadi, Sara, Sadeghi, Erfan, Moradi, Sara, Mirzayeh Fashami, Fatemeh, Nakhaeizadeh, Mehran, Salehi, Sahar, Sofi-Mahmudi, Ahmad, Nasiri, Naser, Mehmandoost, Soheil, Moallef, Soroush, Langeroodi, Shahryar Moradi Falah, Moe, Jessica, Lysyshyn, Mark, Werb, Dan, Buxton, Jane A., and Karamouzian, Mohammad

Published
2024
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7. An emergency-department-initiated outreach program for patients with opioid use disorder is associated with an increase in agonist therapy and engagement in addictions care: a one-year cohort study

Author

Lakkadghatwala, Rukaiyah, Lane, Daniel, Scheuermeyer, Frank, Hilburt, Jesse, Buxton, Jane, Johnson, Cheyenne, Nolan, Seonaid, Sutherland, Christy, Moe, Jessica, Daoust, Raoul, Dong, Kathryn, Christenson, Jim, Miles, Isabelle, Orkin, Aaron, Whyte, Madelyn, and Kestler, Andrew

Published
2024
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10. The Cannabis-Dependent Relationship Between Methadone Treatment Dose and Illicit Opioid Use in a Community-Based Cohort of People Who Use Drugs.

Author

Lake, Stephanie, Kerr, Thomas, Buxton, Jane, Walsh, Zach, Cooper, Ziva, Socías, M, Fairbairn, Nadia, Hayashi, Kanna, and Milloy, M-J

Subjects
cannabis, cohort study, methadone, opioid agonist treatment, opioid use disorder, opioids, Humans, Adolescent, Methadone, Analgesics, Opioid, Cannabis, Opiate Substitution Treatment, Opioid-Related Disorders, Narcotics, Hallucinogens, Cannabinoid Receptor Agonists, Substance Withdrawal Syndrome, Cannabinoids
Abstract

Background: Methadone maintenance treatment (MMT) is an effective treatment for opioid use disorder. However, subtherapeutic dosing may lead to continued opioid use by failing to suppress opioid withdrawal and craving. Preclinical and pilot experimental research suggests that cannabinoids may reduce opioid withdrawal and craving. We sought to test whether the association between low methadone dose and illicit opioid use differs according to concurrent cannabis use patterns. Methods: Data for this study were derived from two community-recruited cohorts of people (≥18 years old) who use illicit drugs in Vancouver, Canada. We used generalized estimating equations to estimate the adjusted association between lower daily MMT dose (

Published
2023

12. Methadone Dose, Cannabis Use, and Treatment Retention: Findings From a Community-based Sample of People Who Use Unregulated Drugs.

Author

Lake, Stephanie, Buxton, Jane, Walsh, Zach, Cooper, Ziva, Socías, M, Fairbairn, Nadia, Hayashi, Kanna, and Milloy, M-J

Subjects
Humans, Methadone, Cannabis, Analgesics, Opioid, Opiate Substitution Treatment, Prospective Studies, Opioid-Related Disorders
Abstract

OBJECTIVES: Lower daily methadone dose is negatively associated with retention in methadone maintenance treatment (MMT). Cannabis use during MMT is common, with many patients reporting its use for opioid withdrawal mitigation. We sought to test whether the association between lower MMT dose and treatment retention differs by concurrent high-frequency cannabis use in a community sample of people on MMT. METHODS: We obtained data from participants initiating MMT in 2 community-recruited prospective cohorts of people who use drugs in Vancouver, Canada. We built multivariable Cox frailty models to estimate the relationships between MMT dose ( 0.05). Structural factors including homelessness and incarceration were significantly and positively associated with treatment discontinuation. CONCLUSIONS: Although we previously found the magnitude and strength of the relationship between lower MMT dose and high-frequency unregulated opioid use to be tempered during high-frequency cannabis use periods, this effect measure modification does not appear to translate to time retained in treatment. Cannabis-based interventions to promote retention in MMT are unlikely to produce long-term benefit without addressing external factors that place MMT patients at increased risk of treatment discontinuation.

Published
2023

29. Frequency of cannabis and illicit opioid use among people who use drugs and report chronic pain: A longitudinal analysis.

Author

Lake, Stephanie, Walsh, Zach, Kerr, Thomas, Cooper, Ziva D, Buxton, Jane, Wood, Evan, Ware, Mark A, and Milloy, MJ

Subjects
Humans, Cannabis, Pain, Opioid-Related Disorders, Analgesics, Analgesics, Opioid, Longitudinal Studies, Prospective Studies, Marijuana Smoking, Adult, Middle Aged, Canada, Female, Male, Pain Management, Chronic Pain, Medical Marijuana, Opioid, Pain Research, Clinical Research, Drug Abuse, Neurosciences, Substance Abuse, 2.1 Biological and endogenous factors, Medical and Health Sciences, General & Internal Medicine
Abstract

BACKGROUND:Ecological research suggests that increased access to cannabis may facilitate reductions in opioid use and harms, and medical cannabis patients describe the substitution of opioids with cannabis for pain management. However, there is a lack of research using individual-level data to explore this question. We aimed to investigate the longitudinal association between frequency of cannabis use and illicit opioid use among people who use drugs (PWUD) experiencing chronic pain. METHODS AND FINDINGS:This study included data from people in 2 prospective cohorts of PWUD in Vancouver, Canada, who reported major or persistent pain from June 1, 2014, to December 1, 2017 (n = 1,152). We used descriptive statistics to examine reasons for cannabis use and a multivariable generalized linear mixed-effects model to estimate the relationship between daily (once or more per day) cannabis use and daily illicit opioid use. There were 424 (36.8%) women in the study, and the median age at baseline was 49.3 years (IQR 42.3-54.9). In total, 455 (40%) reported daily illicit opioid use, and 410 (36%) reported daily cannabis use during at least one 6-month follow-up period. The most commonly reported therapeutic reasons for cannabis use were pain (36%), sleep (35%), stress (31%), and nausea (30%). After adjusting for demographic characteristics, substance use, and health-related factors, daily cannabis use was associated with significantly lower odds of daily illicit opioid use (adjusted odds ratio 0.50, 95% CI 0.34-0.74, p < 0.001). Limitations of the study included self-reported measures of substance use and chronic pain, and a lack of data for cannabis preparations, dosages, and modes of administration. CONCLUSIONS:We observed an independent negative association between frequent cannabis use and frequent illicit opioid use among PWUD with chronic pain. These findings provide longitudinal observational evidence that cannabis may serve as an adjunct to or substitute for illicit opioid use among PWUD with chronic pain.

Published
2019

30. Undergraduate Students' Perspectives on the Impact of a Prison Health Course

Author

Cameron, Rose B., McLeod, Katherine E., Donnelly, Leeann, Buxton, Jane A., and Elwood Martin, Ruth

Abstract

Objective: The stigmatisation of incarceration has significant negative effects on the health and well-being of individuals and communities. At the University of British Columbia in Canada, an undergraduate course on prison health included instruction by people with lived experience of incarceration as part of a teaching approach aimed to reduce stigma. In this study, we sought to understand the impact of this course as described by students. Design: Qualitative interviews with students who completed the course in 2017 were conducted by another former student of the course. Interviews were transcribed and interpretive descriptive methods were used to elucidate findings. Results: Nine former students participated in the study, eight (89%) were women and the median age was 23 years. Analysis yielded the following themes: (1) learning from people with lived experience, (2) de-mystifying through knowledge and understanding, (3) broadened perspectives and self-reflection, (4) future choices and actions and (5) changing views on incarceration. Conclusion: Findings suggest that approaches to address stigma in teaching prison health in an undergraduate course provided students with a deepened understanding of health inequities and determinants of health; increased feelings of compassion and interest in health equity for populations impacted by incarceration; and fostered opportunities for reflection, critical thinking and broadened perspectives.

Published
2021
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50. "They Give you a bus Ticket and They Kick you Loose": A Qualitative Analysis of Post-Release Experiences among Recently Incarcerated Women Living with HIV in Metro Vancouver, Canada.

Author

Erickson, Margaret, Deering, Kathleen, Ranville, Flo, Bingham, Brittany, Young, Pam, Korchinski, Mo, Buxton, Jane, Elwood Martin, Ruth, Shannon, Kate, and Krüsi, Andrea

Subjects
RISK of violence, SUBSTANCE abuse treatment, INTELLECT, CULTURAL identity, HEALTH attitudes, CORRECTIONAL institutions, INDEPENDENT living, QUALITATIVE research, IMPRISONMENT, CLOTHING & dress, HIV-positive persons, INTERVIEWING, PRISON psychology, HIV infections, DESCRIPTIVE statistics, EMOTIONAL trauma, TRANSPORTATION, CONCEPTUAL structures, RESEARCH methodology, ACTION research, WOMEN'S health, HOMELESSNESS, SOCIAL support, TRANSCULTURAL medical care, SOCIAL stigma, PSYCHOLOGICAL vulnerability
Abstract

To explore the transition from correctional facilities to community among women living with HIV in Vancouver, Canada, we interviewed 19 recently incarcerated women and 6 service providers. Findings highlighted heightened risk of violence at release, a lack of immediate supports, challenges accessing safe housing and addictions treatment, and interruptions in HIV treatment and care. In the face of structural barriers, women blamed themselves for not being able to break the cycle of incarceration. There is a critical need for enhanced pre-release planning with a priority on housing and substance use services, alongside supports that are trauma-and violence-informed and culturally safe. [ABSTRACT FROM AUTHOR]

Published
2024
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