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Your search keyword '"Budäus, L."' showing total 287 results
Start Over Author "Budäus, L." Publication Type Academic Journals
287 results on '"Budäus, L."'

10. O03 - Complete biochemical response below 0.1 ng/ml predicts long-term therapy-free survival of prostate cancer patients treated with salvage lymph node dissection via PSMA-radioguided surgery

Author

Knipper, S., Lischewski, F., Koehler, D., Eiber, M., van Leeuwen, F.W.B., de Barros, H., Berrens, A.C., van Leeuwen, P., van der Poel, H., Ambrosini, F., Falkenbach, F., Budäus, L., Steuber, T., Graefen, M., Tennstedt, P., Gschwend, J.E., Horn, T., Heck, M.M., and Maurer, T.

Published
2023
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26. 1225 - Prostate evaluation for clinically important disease: Sampling using image-guidance or not? (The PRECISION study, NCT02380027)

Author

Kasivisvanathan, V., Rannikko, A.S., Borghi, M., Panebianco, V., Mynderse, L.A., Vaarala, M.H., Briganti, A., Budäus, L., Hellawell, G., Hindley, R.G., Roobol, M.J., Eggener, S., Ghei, M., Villers, A., Bladou, F., Villeirs, G.M., Virdi, J., Boxler, S., Robert, G., Singh, P.B., Venderink, W., Hadaschik, B.A., Ruffion, A., Hu, J., Margolis, D., Crouzet, S., Klotz, L., Taneja, S.S., Pinto, P., Gill, I., Allen, C., Giganti, F., Freeman, A., Morris, S., Punwani, S., Williams, N., Brew-Graves, C., Takwoingi, Y., Emberton, M., and Moore, C.M.

Published
2018
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43. Influence of low-molecular-weight heparin dosage on red blood cell transfusion, lymphocele rate and drainage duration after open radical prostatectomy.

Author

Schmitges, J., Trinh, Q.-D., Jonas, L., Budäus, L., Larbig, R., Schlomm, T., Karakiewicz, P.I., Heinzer, H., Huland, H., Graefen, M., and Steuber, T.

Subjects
RED blood cell transfusion, MOLECULAR weights, PROSTATECTOMY, HEPARIN, COMPARATIVE studies, BODY mass index
Abstract

Abstract: Background: To assess the rates of red blood cell (RBC) transfusions, pelvic lymphoceles, and prolonged drainage duration in patients after radical prostatectomy (RP) receiving perioperative bridging with low-molecular-weight heparin (LMWH). Patients and methods: Between 2006 and 2009, 114 RP patients receiving bridging therapy with 60 mg (n = 63) or ≥80 mg (n = 51) Enoxaparin/d were compared to 1327 consecutive RP patients receiving 40 mg Enoxaparin/d. Logistic regression models were used to test the effect of LMWH dosage on all three outcomes. Covariables included age, body mass index (BMI), Charlson comorbidity index (CCI), prostate volume, pelvic lymph node dissection, and pathological stage. Results: The RBC transfusion rates in patients treated with 40, 60 and ≥80 mg were 4.9, 9.5 and 19.6%, respectively (p < 0.001). The respective lymphocele rates were 6.4, 3.2 and 2.0% (p = 0.26). The respective rates of drainage duration of ≥4 days were 6.7, 4.8 and 16.7% (p = 0.088). After adjusting for confounding factors, patients receiving ≥80 mg were 4.1-fold more likely to be transfused than patients receiving prophylactic LMWH (p = 0.02). Similarly, patients receiving ≥80 mg were 3.2-fold more likely to have a drainage duration of ≥4 days than patients receiving prophylactic LMWH (p = 0.03). Conclusions: Patients with a perioperative bridging with LMWH in RP are more likely to receive a RBC transfusion and to have prolonged drainage duration. Conversely, bridging therapy was not associated with an increased risk of lymphocele formation. [Copyright &y& Elsevier]

Published
2012
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44. Predicting the risk of lymph node invasion during radical prostatectomy using the European association of urology guideline nomogram: A validation study.

Author

Schmitges, J., Karakiewicz, P.I., Sun, M., Abdollah, F., Budäus, L., Isbarn, H., Bianchi, M., Trinh, Q.-D., Schlomm, T., Chun, F.K., Graefen, M., and Steuber, T.

Subjects
PROSTATECTOMY, LYMPH node cancer, PROSTATE surgery, PROSTATE cancer, CANCER invasiveness, NOMOGRAPHY (Mathematics), MEDICAL statistics, ILIAC vein
Abstract

Abstract: Background: The 2011 European Association of Urology (EAU) guidelines for prostate cancer recommend a pelvic lymph node dissection (PLND) at radical prostatectomy (RP) in all individuals with a nomogram predicted lymph node invasion (LNI) risk of >7%. Methods: To test the performing characteristics for several thresholds (1–14%) and to examine the overall accuracy and calibration plot of the EAU nomogram at our institution. The study population consisted of 3081 patients treated with RP and PLND limited to the obturator fossa and the external iliac vein between 2008 and 2010 at a single European institution from Germany. More extensive PLNDs were performed at the surgeon’s discretion. Results: Overall, 260 patients (9.2%) had LNI. The 7% threshold would have avoided 30% of PLNDs, at the cost of missing 8% of patients with LNI. The use of 8% and 9% threshold would have allowed the avoidance of respectively 39% and 48% of PLNDs, at the cost of missing respectively 12% and 14% of patients with LNI. The accuracy of the LNI nomogram was 78%, and the unadjusted departure from ideal calibration was 5.3%. Conclusions: We confirmed adequate accuracy and calibration of the LNI nomogram. The 7% cut-off may be overly conservative. Better trade-offs between avoided PLNDs and missed LNI cases may be achieved with a limit of 8 or even 9%. [Copyright &y& Elsevier]

Published
2012
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45. Impact of annual surgical volume on length of stay in patients undergoing minimally invasive prostatectomy: A population-based study.

Author

Budäus, L., Morgan, M., Abdollah, F., Zorn, K.C., Sun, M., Johal, R., Thuret, R., Abdo, A., Schmitges, J., Isbarn, H., Jeldres, C., Perrotte, P., Graefen, M., and Karakiewicz, P.I.

Subjects
PROSTATECTOMY, LENGTH of stay in hospitals, CANCER invasiveness, LOGISTIC regression analysis, PROSTATE surgery, PROSTATE cancer, COMORBIDITY
Abstract

Abstract: Background: On average, patients remain hospitalized no more than 2 days after MIRP. The aim of our study was to examine the temporal trends in length of stay ≥3 days and to test the relationship between annual surgical volume (ASV) and annual hospital volume (AHV) and length of stay ≥3 days in patients undergoing MIRP. Material and methods: Within the Florida Hospital Inpatient Datafile, 2439 men who were treated with MIRP for prostate cancer between 2005 and 2008 were identified. Temporal trends were assessed and uni and multi-variable logistic regression models tested the relationship between ASV, AHV and length of stay ≥3 days. Results: The average length of stay decreased from 2.4 in 2005 to 1.7 days in 2008. Length of stay ≥3 days was recorded in 13.6% of patients and the proportion of patients staying more than ≥3 days decreased over time (25.5–12.2%; Chi Square trend p < 0.001). After stratification into low (<1–15 MIRPs) vs. intermediate (16–63 MIRPs) vs. high ASV tertiles (≥64 MIRPs) the proportion of patients with length of stay ≥3 days were 29.1; 13.2 and 11.1%. In multivariable logistic regression models predicting length of stay ≥3 days, ASV, year of surgery and comorbidities achieved independent predictor status and MIRP patients operated by highest ASV tertile surgeons were 71% (p < 0.001) less likely to be hospitalized for more than 3 days. Conclusion: The length of stay after MIRP decreased between 2005 and 2008. Surgical expertise represented one of the main determinants of shorter length of stay. [Copyright &y& Elsevier]

Published
2011
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