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Abstract Objective: To determine the level of serotonin in patients of vasovagal syncope and postural tachycardia syndrome after head-up tilt test. Method: The cross-sectional analytical study was conducted at the Islamic International Medical College and the Department of Electrophysiology, Armed Forces Institute of Cardiology, Rawalpindi, from April 2017 to March 2018. Group A comprised cases of vasovagal syncope, group B had patients of postural tachycardia syndrome, and group C had healthy controls. Cases were chosen on the basis of history, episodes of syncope and findings of head-up tilt test. After the test, blood samples were taken for hormonal analysis of serotonin using enzyme-linked immunosorbent assay. Data was analysed using SPSS 21. Results: Of the 80 subjects, 35(43.8%) were in group A, 35(43.8%) in group B and 10(12.4%) in group C. Mean serotonin value in group A was 918.39±380.16nM, in group B it was 1188.70±449.55nM., while in control group C the mean value was 771.40±376.14nM (p

Objective: This study aimed to determine the association of premature ventricular contractions burden of less than 20% with NT-pro BNP levels in patients with preserved left ventricular function. Study Design: Case control analytical study. Place and Duration of Study: It was conducted in physiology department of Islamic International Medical College (IIMC) in collaboration with Armed Forces Institute of Cardiology (AFIC) during the period of 18 April 2016 to 20 March 2018. Materials and Methods: The study comprised a total of fifty participants which included 40 diagnosed patients of premature ventricular contractions (PVCs) and 10 healthy subjects (with no PVCs). PVCs burden was calculated by Holter monitoring report and echocardiography was done to determine left ventricular ejection fraction. Patients with burden>20% and Ejection fraction