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Your search keyword '"Athanasiou, Stavros"' showing total 333 results
Start Over Author "Athanasiou, Stavros" Publication Type Academic Journals
333 results on '"Athanasiou, Stavros"'

5. Propofol Versus Dexmedetomidine for Conscious Sedation During Vaginal Hysterectomy With Pre-emptive Local Anesthesia: A Prospective Cohort Study.

Author

HADZILIA, SOFIA, GRIGORIADIS, THEMOS, PRODROMIDOU, ANASTASIA, STAMATAKIS, EMMANOUIL, PAPADOPOULOU, DIMITRA, ZACHARAKIS, DIMITRIOS, ATHANASIOU, STAVROS, and VALSAMIDIS, DIMITRIOS

Abstract

Background/Aim: Hysterectomy is the most frequent gynecological surgery. Vaginal hysterectomy (VH) seems to be related to favorable perioperative outcomes compared to abdominal or laparoscopic approaches. As the population ages, anesthesia that is safer for the elderly, such as local anesthesia (LA) with conscious sedation, is gaining popularity and is related to favorable outcomes in patients’ recovery compared to general or regional anesthesia. We aimed to evaluate the efficacy of dexmedetomidine versus propofol for women undergoing VH for uterine prolapse under LA and conscious sedation. Patients and Methods: A prospective study on 40 women with uterine prolapse stage ≥3 who had VH under LA with conscious sedation under either dexmedetomidine (n=20) or propofol (n=20) was performed. A standardized surgical approach with continuous hemodynamic monitoring and sedation assessment using the Ramsay Sedation Scale (RSS) was conducted. The primary endpoint of the study was to determine the percentage of patients receiving intraoperative fentanyl. Results: Analysis of outcomes demonstrated a significant reduction in the proportion of patients requiring intraoperative rescue fentanyl (35% vs. 5%, respectively, p=0.04) and in postoperative pain scores, with more patients achieving an optimal RSS score of 3 in the dexmedetomidine group. Conclusion: Based on the findings of the present study, dexmedetomidine offered superior analgesia and patient comfort compared to propofol, suggesting a favorable anesthetic profile for VH under LA. [ABSTRACT FROM AUTHOR]

Published
2024
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26. CO 2 Laser versus Sham Control for the Management of Genitourinary Syndrome of Menopause: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Author

Prodromidou, Anastasia, Zacharakis, Dimitrios, Athanasiou, Stavros, Kathopoulis, Nikolaos, Varthaliti, Antonia, Douligeris, Athanasios, Michala, Lina, Athanasiou, Veatriki, Salvatore, Stefano, and Grigoriadis, Themos

Subjects
GENITOURINARY diseases, RANDOMIZED controlled trials, CARBON dioxide, LASERS, VAGINAL dryness, LASER therapy
Abstract

In the context of the menopausal transition, genitourinary syndrome of menopause (GSM) refers to a range of genitourinary symptoms, from vaginal dryness to dysuria and urinary urgency. While hormonal treatments are standard, their associated side effects have driven the exploration of alternatives like vaginal CO2 laser. We aimed to evaluate the randomized controlled trials (RCTs) comparing vaginal CO2 laser treatment for GSM to sham controls. This systematic review sourced four electronic databases until June 2023. The analysis incorporated seven RCTs with 407 women. The CO2 laser and sham control were comparable for most parameters, including the female sexual function index (FSFI) and visual analogue scale (VAS) for dyspareunia, vaginal health index, pH, and patient satisfaction. However, the CO2 laser group showed significant improvement in the vaginal assessment scale for GSM symptoms. Sensitivity analyses revealed that parameters like FSFI showed significant differences in favor of CO2 laser group upon the exclusion of specific studies. In conclusion, vaginal CO2 laser therapy emerges as a promising alternative for GSM management, especially for most bothersome GSM symptoms; however, the need for further well-designed RCTs remains to validate its broad safety and efficacy. [ABSTRACT FROM AUTHOR]

Published
2023
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27. Letters to the Editor

Author

Gonzalez, Pablo, Salvatore, Estefano, Athanasiou, Stavros, Borrego, Rafael Sanchez, Leibaschoff, Gustavo, Tserotas, Konstantino, Escribano, Juan, Zerbinati, Nicola, and Awad, David Vasquez

Published
2019
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30. To the Editor

Author

Gonzalez, Pablo, Salvatore, Estefano, Athanasiou, Stavros, Borrego, Rafael Sanchez, Leibaschoff, Gustavo, Tserotas, Konstantino, Escribano, Juan, Zerbinati, Nicola, and Awad, David Vasquez

Published
2019
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35. sFLT1, PlGF, the sFLT1/PlGF Ratio and Their Association with Pre-Eclampsia in Twin Pregnancies—A Review of the Literature.

Author

Sapantzoglou, Ioakeim, Rouvali, Angeliki, Koutras, Antonios, Chatziioannou, Maria Ioanna, Prokopakis, Ioannis, Fasoulakis, Zacharias, Zachariou, Eleftherios, Douligeris, Athanasios, Mortaki, Anastasia, Perros, Paraskevas, Ntounis, Thomas, Pergialiotis, Vasilios, Domali, Ekaterini, Athanasiou, Stavros, Daskalakis, George, Rodolakis, Alexandros, Panagopoulos, Periklis, and Pappa, Kalliopi I.

Subjects
MULTIPLE pregnancy, LITERATURE reviews, FETOFETAL transfusion, PREGNANCY outcomes, PREECLAMPSIA, CINAHL database
Abstract

Twin pregnancies demonstrate a 2–3-fold higher chance of developing PE compared to singletons, and recent evidence has demonstrated that the sFLT1/PIGF ratio is strongly associated with PE, adverse pregnancy outcomes, as well as imminent deliveries due to PE complications. The primary objective of this systematic review was to summarise the available data on the levels of sFLT1, PlGF and their ratios in twin pregnancies and to investigate their association with the development of PE, adverse pregnancy outcomes and the timing of the delivery. A systematic search of Ovid Embase, Web of Science, Science Direct, PubMed, Ovid Medline, Google Scholar and CINAHL was carried out. sFLT1 levels and the sFLT1/PIGF ratio appeared higher in twins compared to singleton pregnancies, especially in the third trimester, while PlGF levels appeared higher up until the third trimester, with their values showing no difference or being even lower than in singletons thereafter. The sFLT1/PIGF ratio has been reported to be an independent marker of adverse outcomes related to pre-eclampsia and is associated with the mean time until delivery in an inverse manner. Further research is required in order to establish the optimal sFLT1/PIGF cut-off values and to stratify the risk of adverse outcomes in twin pregnancies. [ABSTRACT FROM AUTHOR]

Published
2023
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