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This study focuses on baryons that consists of one heavy quark and two light quarks. This paper explores the mass spectra of radial and excited states for all singly heavy baryons, employing the Hypercentral Constituent Quark Model (hCQM). In this model, we incorporated higher-order corrections, including second-order corrections in mass, specifically considering spin-dependent terms. This methodology enables a more accurate observation of the correct spin splitting order. We have determined important properties, including magnetic moment, transition magnetic moment, radiative decay width and strong decay width. [ABSTRACT FROM AUTHOR]

Diabetic nephropathy (DN) is one of the most common kidney diseases, but its exact pathophysiology remains unknown. Toll-like receptors (TLRs) are innate immune receptors that recognize pathogen- and danger-associated molecular patterns, which can result in an inflammatory response. TLR4, TLR2, TLR5, TLR7, TLR8, TLR9, and TLR11 are essential in the pathogenesis of DN, according to recent evidence collected from both in vivo and in vitro studies. Studies have shown that TLR2 and TLR4 expression is higher in patients with renal failure and nephrotic diabetes. They also play critical roles in podocyte injury and inflammation caused by high glucose. TLR2 and TLR4 may be helpful therapeutic targets to prevent or delay DN in patients with type 2 diabetes mellitus. Additionally, TLR7 may contribute to kidney damage in type 1 diabetes mellitus, whereas downregulation of TLR9 expression inhibits inflammation and apoptosis pathways associated with DN. [ABSTRACT FROM AUTHOR]

In today's world, high variability of body mass index (BMI) is known as a significant global health problem that can lead to many negative impacts on the cardiovascular system, including atrial fibrillation (AF) and coronary heart disease. The current systematic review aims to elucidate the effect of variability in BMI on the risk of cardiovascular outcomes. Four databases, including PubMed, Scopus, MEDLINE, and CENTRAL, were searched. All related articles up to 10 June 2022, were obtained. Titles, abstracts, and full texts were reviewed. After screening abstracts and full texts, four articles were included in our study. In these four cohort studies, 7,038,873 participants from the USA and South Korea were involved. These articles generally considered the BMI and outcomes including cardiovascular disease, AF, and coronary heart disease. All these articles reported an association between the variability of BMI and increased risk of cardiovascular outcomes. Due to the negative impact of the high variability of BMI on the risk of cardiovascular outcomes, health policymakers and practitioners should pay more attention to the significant role of BMI in health problems and physicians might better check the variability of BMI visits to visit. [ABSTRACT FROM AUTHOR]

In this study, singly charm baryons Λ c , Σ c , Ξ c and Ω c have been studied. The known hypercentral Constituent Quark Model (hCQM) has been subjected to an addition of second-order correction term to the mass in spin-dependent term. This has allowed to observe the expected spin-splitting in the correct order and modify the previous findings to a new level. All the other properties have been obtained ranging from magnetic moment to strong decay width along with the linearly observed Regge trajectories. [ABSTRACT FROM AUTHOR]

INTRODUCTION. Subacute thyroiditis (SAT), also known as de Quatrain's thyroiditis or granulomatous thyroiditis, is an inflammatory disease of the thyroid. Most of the time, it manifests in the thirties to fifties and is more common in women. SAT can have either viral or post-viral origin. Some viruses, like influenza, COVID-19, Epstein-Barr virus, cytomegalovirus, hepatitis, coxsackievirus 16, and mumps virus, have been linked to SAT development. The COVID-19 pandemic has affected people's lives all around the world and has changed our attitude toward the treatment of many diseases. It has also made us look deeper into the subject in a way that we would be able to treat this sort of disease with a newer insight. OBJECTIVE. Regarding the importance of this issue, we decided to summarize our extensive searches from online databases, including PubMed, Google Scholar, Medline, Web of Science, and Scopus until February 2023, which we found effective in elucidating the association of subacute thyroiditis and viral diseases. METHOD. Different online databases were searched for narrative review articles, systemic review articles, and original articles, which were published until February 2023. RESULT. According to the included studies, we found that there is a correlation between SAT and several viruses such as Epstein-Barr virus, influenza virus, human immunodeficiency virus, cytomegalovirus, oral and cervical virus, hepatitis, dengue virus, and SARS-COV-2. The effect of each of the viral diseases mentioned in the SAT is given in the text. CONCLUSIONS. According to the results mentioned in the text, because SAT may be challenging for early diagnosis, due to the potential of classic symptoms as well as the interference of similar clinical symptoms between thyrotoxicosis and viral reactions, the correlation between SAT and viral diseases should be considered so that we can avoid misdiagnosis and lateness. [ABSTRACT FROM AUTHOR]

The emerging COVID-19 pandemic led to a dramatic increase in global mortality and morbidity rates. As in most infections, fatal complications of coronavirus affliction are triggered by an untrammeled host inflammatory response. Cytokine storms created by high levels of interleukin and other cytokines elucidate the pathology of severe COVID-19. In this respect, repurposing drugs that are already available and might exhibit antiinflammatory effects have received significant attention. With the in vitro and clinical investigation of several studies on the effect of antidepressants on COVID-19 prognosis, previous data suggest that selective serotonin reuptake inhibitors (SSRIs) might be the new hope for the early treatment of severely afflicted patients. SSRIs' low cost and availability make them potentially eligible for COVID-19 repurposing. This review summarizes current achievements and literature about the connection between SSRIs administration and COVID-19 prognosis. [ABSTRACT FROM AUTHOR]

Objective: This in-vitro study aimed to evaluate and compare the Shear bond strength using Admira Fusion Xtra, an alternative bonding adhesive, and conventional bonding adhesive. Materials and Method: Two hundred seventy sound human maxillary premolars were randomly divided into three groups (n=90) Group 1 (Transbond XT), Group 2 (Fusion Flow), and Group 3 (Fusion Xtra) based on adhesives used for bonding the orthodontic metal brackets. All the samples were stored in artificial saliva and subjected to SBS evaluation using a universal testing machine at a cross speed of 0.5 mm2/min. The failure mode was analyzed using Adhesive Remnant Index (ARI). Statistical analysis was done using an unpaired student t-test and one-way and 3-way ANOVA for the shear bond strength and the Kruskal-Wallis test followed by Mann-Whitney was performed for ARI scores (p<0.01). Result: The mean values of shear bond strength of Admira Fusion Xtra showed statistically significant differences between other evaluated groups (p<0.001). The lowest and highest shear bond strength was attributed to each group respectively. Statistically significant differences were noted in the mean ARI scores between Fusion Xtra and another evaluated group (p<0.01). Conclusion: Admira Fusion Xtra enhances the shear bond strength of orthodontic brackets as compared to the Admira Fusion Flow and conventional orthodontic adhesive. [ABSTRACT FROM AUTHOR]

Byline: Mohsen. Adib-Hajbaghery, Akram. Ansari, Ismail. Azizi-Fini Context: Oral care is an essential aspect of critical care nursing. However, no study has been published on oral care practice of Iranian [...]

By applying multivariate statistical analysis, this research aimed to estimate the heritability and find relationships between the vegetative and reproductive characteristics of Prunus scoparia and Prunus elaeagnifolia. Twenty genotypes of each species were selected randomly from cultivated populations and twenty-two traits including the tree, leaf, flower, nut and kernel attributes were measured. Results showed that there were high levels of genotypic and phenotypic variations among the genotypes of both species. Many of the measurements pertaining to the leaf, flower, nut and kernel, showed very high heritability (H² >90%) in both species, whilst some traits such as shoot diameter in P. scoparia and kernel moisture in both species had very lower heritability (H² <50%). Generally, the heritability of measured traits in P. elaeagnifolia were higher than those of P. scoparia, especially for economically important traits including yield (H² = 94 and H² = 54.61, respectively in P. elaeagnifolia and P. scoparia), nut weight (H² = 97.83 and H² = 85.39.61, respectively in P. elaeagnifolia and P. scoparia) and oil percentage (H² = 75.55 and H² = 61.43, respectively in P. elaeagnifolia and P. scoparia). Stepwise regression analysis revealed that the most influential factors on yield of P. scoparia, were the fruit set, flower diameter and leaf length, whilst for the P. elaeagnifolia, the yield was mostly determined by fruit set and leaf area. The high genetic diversity and heritability of the studied traits, indicates high genetic potential of this germplasm to be utilized in future breeding programs. [ABSTRACT FROM AUTHOR]

The importance of English as an international language and language of education has widely been recognized in the almost all parts of the world. In context of Pakistani education where low literacy rate has always been haunting, the quality of education is another issue, the difference between gender and rural, urban divide also put question mark on whole education system. A sample of 120 students was randomly selected from the list of students of Physical Education Departments (PED) belonging to public sector Universities. The data was collected through questionnaire and analyzed qualitatively and quantitatively. Mean standard deviation and Ttest was used to test the hypotheses. It was found that English proficiency of learners living urban areas was better than learners having rural back ground. The role of teachers was dismal; however learners' attitude towards English proficiency was positive as they were cognizant to the importance of English and keen to learn English. Parents' role in urban area was encouraging than the parents in rural areas. Students' access to quality education and other basic facilities was less in rural area as compared to urban areas. Overall position of English proficiency was unsatisfactory keeping in view the standards of English. [ABSTRACT FROM AUTHOR]

Copyright of Revista Clínica de Ortodontia Dental Press is the property of Dental Press International and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Aims and objectives: The study was undertaken to estimate the availability of literature on PubMed-Medline by Indian orthodontists from 1990 to 2011 by using bibliometric analysis. Materials and methods: Articles available on PubMed-Medline database in time span of 1st January 1990 to 31st December 2011, where authors' affiliation had the words 'Dental' and 'India' were selected. The information collected were: Name of the journal, year of publication, specialty of first author, number of authors, reach of the journal, status of the journal,, state of origin, and type of article. From this data, the performance of specialty of orthodontic was analyzed. Results: Out of total of 242 articles, 189 got published in international journals and 53 in Indian journals. 50 (20.6%) were published in Journal of Clinical Orthodontics followed by 37(15.2%) in American Journal of Orthodontics and Dentofacial Orthopedics. 102 (42.1%) were original research done by authors. 91(37.6%) articles were from institutes in Karnataka, followed by Tamil Nadu (12.8%), Delhi (11.1%) and Maharashtra(9.5%). There seems to be boom in the publication trend since 2006. Conclusion: The results of this study could be used by various professional societies, individual scientists, scholarly institutions and funding organizations to frame essential policies regarding the improvement of the science of orthodontists and to the benefit of common Indians. [ABSTRACT FROM AUTHOR]

The article offers step-by-step instruction for a technique with which bend backs can be given in a lingual instrument with use of light wire pliers.

Diabetes is a widely known disease, which afflicts millions of people annually and is considered one of the leading culprits of mortality and morbidity worldwide. Researchers are making an enormous effort to propose more efficient remedies for the better amelioration of the disease. On the other hand, the public interest in the consumption of herbal medicine for therapeutic purposes is rocketing and the use of these drugs is becoming ubiquitous. Murraya koenigii MK is a tropical tree, originally found in the Indian subcontinent, which is an indispensable piece of the Indian diet and has multipotent medicinal capabilities. The variety of its leaves' hypoglycemic characteristics has been investigated via human, animal, and in vitro studies. This review intends to elaborate on the latest knowledge about the anti-diabetic and hypoglycemic effects of MK in the hope of easing the further application of MK in the alleviation of the diabetes signs and symptoms. [ABSTRACT FROM AUTHOR]

Background: Lipoprotein a (LP(a)), an LDL-like lipoprotein, known as a risk factor for cardiovascular diseases, has a controversial association with diabetic retinopathy in patients with type 2 diabetes-the current systematic review aimed to critically assess the association between LP(a) and diabetic retinopathy., Methods: A systematic review of relevant studies was conducted after a thorough search in PubMed, Scopus, and Google Scholar electronic databases. We used English observational, case-control, and prospective cohort studies published up to August 2022, including type 2 diabetic patients as the population, diabetic retinopathy as the outcome, and LP(a) as the intervention., Result: 17 relevant studies, including 4688 patients with diabetes, were included in this systematic review. While in 13 studies, Lipoprotein(a) was recognized as a risk factor for diabetic retinopathy, only three studies reported no evidence of a relationship between the two. Also, another study showed a mixed outcome of the relationship between LP(a) and diabetic retinopathy., Conclusion: High serum lipoprotein(a) in patients with type 2 diabetes is considered a risk factor for diabetic retinopathy. However, further large-scaled cohort studies are still required to validate this finding., Competing Interests: Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Background: Acute Pulmonary embolism (APE) is considered one of the deadliest cardiovascular diseases. Electrocardiographic (ECG) abnormalities in pulmonary embolism (PE) are increasingly reported. A growing number of studies have recommended that ECG plays a crucial role in the prognostic assessment of PE patients. However, there is scarce data on the prognostic importance of fragmented QRS (fQRS) on outcomes in patients with APE. This study aims to investigate the prognostic value of fQRS in APE patients., Materials and Methods: This is a cross-sectional-analytic study. This study included 280 patients diagnosed with APE admitted to Shahid Madani hospital, Tabriz, Iran. Computed tomography pulmonary angiography (CTPA) was used to diagnose APE. A checklist was prepared for all patients, demographic, clinical characteristics, and Major Adverse Cardiopulmonary events (MACPE), including in-hospital mortality, need for thrombolysis, mechanical ventilation, and surgical embolectomy, were recorded. Patients were divided into two groups: patients who manifested fQRS on their ECG and patients who did not; Then, demographic, clinical characteristics, and MACPE were compared in the two groups, as mentioned earlier. Furthermore, all statistical analyses were carried out using SPSS software., Results: 48 patients (17.14%) had fQRS(+) on their ECG, and 232 patients (82.86%) did not have it on their ECG. In data analysis, 22 patients (8.7%) had in-hospital mortality, 35 patients (13.9%) needed thrombolysis, nine patients (3.9%) required mechanical ventilation, and 13 patients (5.1%) needed surgical embolectomy. fQRS was not significantly associated with in-hospital mortality (P = 0.225), need for thrombolysis (P = 0.684), mechanical ventilation (P = 1.000), and surgical embolectomy (P = 1.000). Demographic and clinical characteristics were also similar in both groups., Conclusions: This study does not support the idea that fQRS on ECG is a valuable predictor of in-hospital mortality, the need for thrombolysis, mechanical ventilation, and surgical embolectomy., Competing Interests: None., (AJCD Copyright © 2023.)

Introduction: Subacute thyroiditis (SAT), also known as de Quatrain's thyroiditis or granulomatous thyroiditis, is an inflammatory disease of the thyroid. Most of the time, it manifests in the thirties to fifties and is more common in women. SAT can have either viral or post-viral origin. Some viruses, like influenza, COVID-19, Epstein-Barr virus, cytomegalovirus, hepatitis, coxsackievirus 16, and mumps virus, have been linked to SAT development. The COVID-19 pandemic has affected people's lives all around the world and has changed our attitude toward the treatment of many diseases. It has also made us look deeper into the subject in a way that we would be able to treat this sort of disease with a newer insight., Objective: Regarding the importance of this issue, we decided to summarize our extensive searches from online databases, including PubMed, Google Scholar, Medline, Web of Science, and Scopus until February 2023, which we found effective in elucidating the association of subacute thyroiditis and viral diseases., Method: Different online databases were searched for narrative review articles, systemic review articles, and original articles, which were published until February 2023., Result: According to the included studies, we found that there is a correlation between SAT and several viruses such as Epstein-Barr virus, influenza virus, human immunodeficiency virus, cytomegalovirus, oral and cervical virus, hepatitis, dengue virus, and SARS-COV-2. The effect of each of the viral diseases mentioned in the SAT is given in the text., Conclusions: According to the results mentioned in the text, because SAT may be challenging for early diagnosis, due to the potential of classic symptoms as well as the interference of similar clinical symptoms between thyrotoxicosis and viral reactions, the correlation between SAT and viral diseases should be considered so that we can avoid misdiagnosis and lateness., Competing Interests: Authors declare no conflict of interest., (National Institute of Public Health NIH – National Research Institute.)

The emerging COVID-19 pandemic led to a dramatic increase in global mortality and morbidity rates. As in most infections, fatal complications of coronavirus affliction are triggered by an untrammeled host inflammatory response. Cytokine storms created by high levels of interleukin and other cytokines elucidate the pathology of severe COVID-19. In this respect, repurposing drugs that are already available and might exhibit anti-inflammatory effects have received significant attention. With the in vitro and clinical investigation of several studies on the effect of antidepressants on COVID-19 prognosis, previous data suggest that selective serotonin reuptake inhibitors (SSRIs) might be the new hope for the early treatment of severely afflicted patients. SSRIs' low cost and availability make them potentially eligible for COVID-19 repurposing. This review summarizes current achievements and literature about the connection between SSRIs administration and COVID-19 prognosis., Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest., (Copyright © 2022 Asadi Anar, Foroughi, Sohrabi, Peiravi, Tavakoli, Kameli Khouzani, Behshood, Shamshiri, Faridzadeh, Keylani, Langari, Ansari, Khalaji, Garousi, Mottahedi, Honari and Deravi.)

Global and regional trends of population aging spotlight major public health concerns. As one of the most common adverse prognostic factors, advanced age is associated with a remarkable incidence risk of many non-communicable diseases, affecting major organ systems of the human body. Age-dependent factors and molecular processes can change the nervous system's normal function and lead to neurodegenerative disorders. Oxidative stress results from of a shift toward reactive oxygen species (ROS) production in the equilibrium between ROS generation and the antioxidant defense system. Oxidative stress and neuroinflammation caused by Amyloid-ß protein deposition in the human brain are the most likely pathogenesis of Alzheimer's disease (AD). Walnut extracts could reduce Amyloid-ß fibrillation and aggregation, indicating their beneficial effects on memory and cognition. Walnut can also improve movement disabilities in Parkinson's disease due to their antioxidant and neuroprotective effect by reducing ROS and nitric oxide (NO) generation and suppressing oxidative stress. It is noteworthy that Walnut compounds have potential antiproliferative effects on Glioblastoma (the most aggressive primary cerebral neoplasm). This effective therapeutic agent can stimulate apoptosis of glioma cells in response to oxidative stress, concurrent with preventing angiogenesis and migration of tumor cells, improving the quality of life and life expectancy of patients with glioblastoma. Antioxidant Phenolic compounds of the Walnut kernel could explain the significant anti-convulsion ability of Walnut to provide good prevention and treatment for epileptic seizures. Moreover, the anti-inflammatory effect of Walnut oil could be beneficial in treating multiple sclerosis. In this study, we review the pharmaceutical properties of Walnut in age-related neurological disorders., Competing Interests: None., (© 2022 The Authors.)

Objective: To evaluate the effects of different adhesion promoters, namely, Enhance LC, Ortho Solo, Assure Universal Bonding Resin and deproteinizing agents such as 5.25% NaOCl, 10% papain gel on the shear bond strength of orthodontic brackets., Materials and Method: The present study was approved by the Ethics Committee of Teerthanker Mahaveer Dental College and Research Centre, affiliated to Teerthanker Mahaveer University, Moradabad, India. Around 150 extracted sound human upper bicuspids were taken and divided into six groups. Group 1 control (37% H 3 PO 4 ), Group 2 (37% H 3 PO 4 + Ortho Solo), Group 3 (37% H 3 PO 4 + Assure Universal Bonding Resin), Group 4 (37% H 3 PO 4 + Enhance LC), Group 5 (5.25% NaOCl + 37% H 3 PO 4 ), and Group 6 (10% papain gel + 37% H 3 PO 4 ). In all the groups ( n = 150) orthodontic metal brackets were bonded with Transbond TM XT and all the samples were subjected for evaluation of shear bond strength using Instron universal testing machine at a cross speed of 0.5 mm/min. The bracket failure mode was examined using Adhesive Remnant Index (ARI). The Kruskal-Wallis test and the Mann-Whitney test were used to compare the shear bond strength. The Chi-square test was used to determine significant differences in the ARI scores among the groups. The significance for all statistical tests was P < 0.05., Results: Mean values of shear bond strength showed statistically significant differences between the evaluated groups ( P < 0.005). The lowest and highest shear bond strength was attributed to Group 1 (control) and Group 2 (Ortho Solo), respectively. No statistically significant difference was noted for the mean ARI scores between control, adhesion promoters, and deproteinized group ( P < 0.05)., Conclusion: It was concluded that adhesion promoters and deproteinizing agents can be used to enhance the shear bond strength of orthodontic brackets. Among all the groups Ortho Solo showed the highest bond strength when used with Transbond TM XT., Competing Interests: There are no conflicts of interest., (Copyright: © 2020 Journal of Orthodontic Science.)

Objectives: To evaluate and compare the effect of different enamel deproteinizing agents on topographic features of enamel and shear bond strength before acid etching., Materials and Method: In total, 120 sound human maxillary premolars were taken and divided into three groups: Group 1 control (37% phosphoric acid (H 3 PO 4 ), Group 2, (5.25% Sodium Hypochlorite (NaOCl)+ 37% H 3 PO 4, and Group 3, (10% Papain gel + 37% H 3 PO 4 ). These groups were further divided into A and B subgroups. In subgroups 1A, 2A, and 3A (n30) topographic features were evaluated using Scanning electron microscope (SEM) at different magnifications. Insub-groups 1B, 2B, and 3B (n90) metal brackets were bonded with Transbond™ XT, and all the samples were subjected for Shear Bond Strength (SBS) evaluation using universal testing machineat a cross speed of 0.5 mm 2 /min. The failure mode was analyzed using adhesive remnant index (ARI). Statistical analysis was done using one-way ANOVA for the shear bond strength, and Kruskal-Wallis test followed by Mann-Whitneywas performed for ARI scores., Results: SEM showed predominance of type 3 etching pattern in control Group (1A) and type 1 and type 2 in deproteinizedGroups (2A and 3A). Mean values of shear bond strength showed statistically significant differences between evaluated groups ( P < 0.005). The lowest and highest shear bond strength was attributed to Group 1B (Control) and 3B (10% papain gel), respectively. Statisticallysignificant differences were noted for the mean ARI scores between control and deproteinized group ( P < 0.05)., Conclusion: 10% papain geland 5.25% NaOCl can be used as deproteinizing agents on enamel surface before acid etchingto enhance the shear bond strength of orthodontic brackets., Competing Interests: There are no conflicts of interest., (Copyright: © 2019 Journal of Orthodontic Science.)