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We performed toxicological evaluation of dental gel ‘Matripin.’ Objective: to assess acute and chronic toxicity of dental gel ‘Matripin’ on mature rats. Animals were kept in standard vivarium conditions. Our findings suggest that ‘Matripin’ is a class 5 drug (virtually non-toxic substance). The assessment of chronic toxicity demonstrated that topical application of ‘Matripin’ does not have any toxic effects on the lungs, heart, spleen, liver, and kidneys, since morphological changes in these organs were similar in the experimental and control groups.

Copyright of Dicle University Journal of Engineering / Dicle Üniversitesi Mühendislik Dergisi is the property of Dicle Universitesi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Experimental Biology (1563-0218) is the property of Al-Farabi Kazakh National University and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Dicle University Journal of Engineering / Dicle Üniversitesi Mühendislik Dergisi is the property of Dicle Universitesi and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Optimal channel switching that provides the highest performance over a set of Gaussian channels with variable utilization costs is investigated in the presence of average power and average cost constraints. First, generic cost functions are considered, and it is shown that the optimal channel switching strategy performs channel switching (time sharing) among at most three different channels and always operates at the average power and average cost limits. Also, for channel switching between two channels, relations between the optimal power levels are obtained depending on the average power limit, and it is proved that the ratio of the optimal power levels is upper bounded by the ratio of the larger noise variance to the smaller one. In addition, for logarithmic cost functions, the convexity properties of the error probability are investigated as a function of power and cost, and the optimal channel switching strategy is shown to employ at most two channels, which can easily be determined based on specific formulas, when the average power limit is larger than a certain threshold. Numerical examples are presented to provide illustrations of the theoretical results. [ABSTRACT FROM PUBLISHER]

In this study, optimal and suboptimal receivers are investigated for code-multiplexed transmitted-reference (CM-TR) ultra-wideband systems. First, a single-user scenario is considered, and a CM-TR system is modeled as a generalized noncoherent pulse-position modulated system. Based on that model, the optimal receiver that minimizes the bit error probability is derived. Then, it is shown that the conventional CM-TR receiver converges to the optimal receiver under certain conditions and achieves close-to-optimal performance in practical cases. Next, multi-user systems are considered, and the conventional receiver, blinking receiver, and chip discriminator are investigated. Also, the linear minimum mean-squared error (MMSE) receiver is derived for the downlink of a multi-user CM-TR system. In addition, the maximum likelihood receiver is obtained as a performance benchmark. The practicality and the computational complexity of the receivers are discussed, and their performance is evaluated via simulations. The linear MMSE receiver is observed to provide the best trade-off between performance and complexity/practicality. Copyright © 2011 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]

In this study, the jointly optimal power control with signal constellation randomization is proposed for the downlink of a multiuser communications system. Unlike a conventional system in which a fixed signal constellation is employed for all the bits of a user (for given channel conditions and noise power), power control with signal constellation randomization involves randomization/time-sharing among different signal constellations for each user. A formulation is obtained for the problem of optimal power control with signal constellation randomization, and it is shown that the optimal solution can be represented by a randomization among (K+1) or fewer distinct signal constellations for each user, where K denotes the number of users. In addition to the original nonconvex formulation, an approximate solution based on convex relaxation is derived. Then, detailed performance analysis is presented when the receivers employ symmetric signaling and sign detectors. Specifically, the maximum asymptotical improvement ratio is shown to be equal to the number of users, and the conditions under which the maximum and minimum asymptotical improvement ratios are achieved are derived. Numerical examples are presented to investigate the theoretical results, and to illustrate performance improvements achieved via the proposed approach. [ABSTRACT FROM PUBLISHER]

Optimal detector randomization is studied for the downlink of a multiuser communications system, in which users can perform time-sharing among multiple detectors. A formulation is provided to obtain optimal signal amplitudes, detectors, and detector randomization factors. It is shown that the solution of this joint optimization problem can be calculated in two steps, resulting in significant reduction in computational complexity. It is proved that the optimal solution is achieved via randomization among at most minK,Nd detector sets, where K is the number of users and \Nd is the number of detectors at each receiver. Lower and upper bounds are derived on the performance of optimal detector randomization, and it is proved that the optimal detector randomization approach can reduce the worst-case average probability of error of the optimal approach that employs a single detector for each user by up to K times. Various sufficient conditions are obtained for the improvability and nonimprovability via detector randomization. In the special case of equal crosscorrelations and noise powers, a simple solution is developed for the optimal detector randomization problem, and necessary and sufficient conditions are presented for the uniqueness of that solution. Numerical examples are provided to illustrate the improvements achieved via detector randomization. [ABSTRACT FROM AUTHOR]

Geochemical and sedimentological analyses and radionuclide ( 210 Pb and 137 Cs) dating of three cores from the Bosporus outlet area of the Black Sea, north of Istanbul, were conducted to assess the sources and history of heavy metal pollution. The sedimentary succession in the shelf core KD12-01 consists mainly of clay (49–80%) and silt (15–41%). Radionuclide dating of the core indicates that it consists of old sediments that are uncontaminated with heavy metals. In contrast, cores KD12-04 and KD12-07 recovered from −350 m and −304 m m in the upper slope area represent sediments consisting of silt and clay that were deposited since at least the last 120 years and 60 years, respectively. The latter core contains two mass-flow units represented by relatively old sedimentary material according to the low 210 Pb activity and relatively low heavy metal contents. The upper 40 and 48 cm of cores KD 12-04 and KD 12-07 represent sediments deposited since 1970s and 1980s that are significantly polluted with Cu, Ni, Zn, Mo, Pb and Cr, Cu, Co, Ni, Mo, Pb, Zn, respectively. However, high Pb and Cr concentrations with high TOC contents date back to early part of the 20th century in core KD 12-04. The geochemical data, together with the high 137 Cs concentrations of the contaminated sediments, strongly suggest that the pollution is mainly delivered to the western and north western Black Sea by the large European rivers, from there transported to the study area by the rim current, and deposited in the sediments under anoxic conditions. [ABSTRACT FROM AUTHOR]