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Copyright of Journal of Hainan Medical University is the property of Journal of Hainan Medical College Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Prataculturae Sinica is the property of Acta Prataculturae Sinica Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Yellow River is the property of Editorial Board of Yellow River and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Natural Disasters is the property of Gai Kan Bian Wei Hui and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Advances in Water Science / Shuikexue Jinzhan is the property of Editorial Board of Advances in Water Science and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Pearl River is the property of Pearl River Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To explore the intrinsic relationship between circadian clock and cell cycle in osteoarthritis(OA) chondrocytes, especially the regulation of cell cycle-related genes by the clock gene Bmal1. Methods The chondroid ATDC5 cells induced by insulin-transfering-selenium(ITS) were divided into control group, OA group and LV-Bmal1 group. The cell viability of each group was detected by CCK8 method. The expression of Bmal1, Per1, Wee1, Cdk1, Ccnb1 and Mmp13 mRNA in each group was detected by RT-qPCR. The expression of BMAL1, PER1, WEE1, CDK1, CCNB1 and MMP13 protein in each group was detected by Western blot. The effects of Bmal1 on different stages of cell cycle and apoptosis was analyzed by flow cytometry. The regulation of Bmal1 on Per1, Wee1, Cdk1, Ccnb1 and Mmp13 and their roles in OA were analyzed. Results Compared with the normal group, the cell viability of the OA group was increased, the relative mRNA expression of Bmal1 and Wee1 in the OA group decreased, and the relative mRNA expression of Per1, Cdk1, Ccnb1 and Mmp13 increased significantly. The cell viability of LV-Bmal1 group decreased, the relative expression of Bmal1 and Wee1 mRNA increased, and the relative expression of Per1, Cdk1, Ccnb1 and Mmp13 mRNA decreased(P＜0.05). Correlation analysis showed that Bmal1 was positively correlated with Wee1 and they were negatively correlated with Per1, Cdk1, Ccnb1 or Mmp13. The results of Western blot showed that protein expression in different groups were consistent with the trend of PCR. The results of cell cycle and apoptosis showed that compared with the normal group, the S phase and G2/M phase of the OA group were shortened, the proportion of cells decreased significantly, and the proportion of early and late apoptosis increased. The S phase and G2/M phase of the LV-Bmal1 group were prolonged, the proportion of cells was increased, and the proportion of early and late apoptosis was decreased. Conclusions Circadian clock gene Bmal1 in inflammatory chondrocytes might regulate the expression of cell cycle-related genes. [ABSTRACT FROM AUTHOR]

Copyright of Acta Agronomica Sinica is the property of Crop Science Society of China and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Agronomica Sinica is the property of Crop Science Society of China and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Science & Technology of Food Industry is the property of Science & Technology of Food Industry Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The coupling relationship between land surface processes and atmospheric boundary layer is one of the key links and difficulties in understanding the thermal effect over the Qinghai-Xizang Plateau. Based on the surface and radiosonde observation data of Nagqu Plateau Climate and Environment Observation and Research Station in May, July and October 2019, this paper analyzes the surface energy budget, the daily and seasonal variations of vertical profile of atmospheric temperature and humidity, in Nagqu Area of the Qinghai-Xizang Pla‐ teau, and discusses the evolution law of the atmospheric boundary layer height in different seasons in this region. The results show that the convective boundary layer is 2842 m high in sunny days due to the influence of diurnal net radiation intensity during the observation period in May. It is 1481 m high in cloudy day, which is relatively low, and the strong convective weather may change it into a stable boundary layer. In the meanwhile, the ex‐ change between the sensible heat and the latent heat in the near surface atmosphere provides energy support for the maintenance and development of the atmospheric boundary layer. The vertical profile of potential temperature and specific humidity can correctly reflect the seasonal difference of atmospheric boundary layer height in gqu Area. The height of the convective boundary layer is highest in May, less high in October and the lowest in July while the stable boundary layer is highest in July, less high in May and lowest in October. [ABSTRACT FROM AUTHOR]

Copyright of Engineering Science Research & Application is the property of Omniscient Pte. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Plateau Meteorology is the property of Plateau Meteorology Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of International Chinese Teaching is the property of Beijing Language & Culture University Press Co. Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Chongqing University of Posts & Telecommunications (Natural Science Edition) is the property of Chongqing University of Posts & Telecommunications and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Plateau Meteorology is the property of Plateau Meteorology Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Prataculturae Sinica is the property of Acta Prataculturae Sinica Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Jilin University (Medicine Edition) is the property of Jilin University Press and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To compare the difference of magnetic resonance apparent diffusion coefficient （ADC）values of endometrial carcinoma between p53 gene mutation group and non-p53 gene mutation group，and to explore the feasibility of using ADC values to predict molecular typing of endometrial cancer （EC）. Methods Preoperative pelvic magnetic resonance imaging （MRI） examination data of 70 endometrial carcinoma（EC） patients were collected，whom were confirmed by surgical pathology and diagnosed by molecular typing. The patients were divided into p53-mutation group（n=40）and non-p53 mutation group（n=30）according to the molecular typing results. ADC values were manually measured on post-processed workstation. The differences of tumoral ADC values between the two groups were compared. The receiver of curve（ROC）and the area under the curve（AUC）for predicting molecular typing of EC was calculated，and the diagnostic performance of predicting p53-mutation status of EC based on ADC measurements was respectively calculated. Results For the p53-mutation group，the ADCmean， ADCmax and ADCmin were （845.9±156.7）×10-6 mm2 /s，（964.9±175.7）×10-6 mm2 /s，and （738.5± 170.7）×10-6 mm2 /s，respectively and （694.3±93.0）×10-6 mm2 /s，（794.0±112.2）×10-6 mm2 /s and （593.5±108.5）×10-6 mm2 /s，respectively for the non-p53 mutation group. The ADCmean value in the p53- mutation group was significantly higher than that in the non-p53 mutation group（P<0.05）. The ROC was 0.787 with a 95% CI of 0.655-0.919. When the ADCmean=820.6×10-6 mm2 /s was taken as the critical value，the accuracy，sensitivity，specificity，positive predictive value and negative predictive value was 74.5%，53.8%，94.4%，93.3% and 58.6%，respectively in determining the p53-mutation status of EC on MRI. Conclusion The ADC value on preoperative MRI could be used as an imaging indicator to predict the molecular subtypes of EC. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Food Safety & Quality is the property of Journal of Food Safety & Quality Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Petroleum Refinery Engineering is the property of Petroleum Refinery Engineering Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Evaluation & Analysis of Drug-Use in Hospitals of China is the property of Evaluation & Analysis of Drug-Use in Hospitals of China Editorial Board and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Pesticide Science / Nongyaoxue Xuebao is the property of Chinese Journal of Pesticide Science and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Medicine & Health is the property of Journal of Modern Medicine & Health and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Applied Entomology is the property of Chinese Journal of Applied Entomology, Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: Multimodal analgesia effectively alleviates pain by additives and synergistic effect various drugs. It can avoid drug dependence and reduce adverse reactions caused by drug overdose. OBJECTIVE: To analyze the analgesic effect of morphine versus cocktail in multimodal analgesia of total knee arthroplasty (TKA). METHODS: Totally 148 patients undergoing primary unilateral TKA were enrolled. The patients were assigned by analgesic modes: group A (n=50) received the epidural injection of 3 mg of morphine before epidural tube removed; group B (n=46) was given the epidural injection of 3 mg of morphine and local injection of cocktail surrounding the knee joint before epidural tube removed; group C (n=52), received the epidural injection of same volume of normal saline and local injection of cocktail surrounding the knee joint. The patients in each group had the osteoarthritis and limited range of movement preoperatively. The postoperative Visual Analogue Scale score, muscle strength, nausea, vomiting, pruritus, and the first urination time were compared among groups. RESULTS AND CONCLUSION: (1) The postoperative Visual Analogue Scale scores at rest and in activity in the group C were significantly higher than those in the groups A and B at 6 and 12 hours (P < 0.05). The q test results showed that the scores showed no significant differences between groups B and C (P > 0.05). The scores at 24 and 36 hours did not differ significantly among groups (P > 0.05). The administration rate of dezocine showed no significant difference among groups (P > 0.05). (2) The muscle strength at postoperative 6 and 12 hours in the group C was significantly higher than that in the groups A and B (P < 0.05), and no significant difference was found between groups A and B through q test (P > 0.05). (3) The incidences of urinary retention, nausea, vomiting and pruritus in the group C were significantly less than those in the groups A and B (P < 0.05), and there was no significant difference between groups A and B (P > 0.05). (4) In summary, in multimodal analgesia of TKA, epidural anesthesia of local injection of cocktail without morphine can significantly improve the early muscle strength, and reduce the complications of urinary retention, nausea, vomiting and pruritus. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Zhengzhou University (Natural Science Edition) is the property of Journal of Zhengzhou University (Natural Science Edition) Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Transactions of the Chinese Society of Agricultural Engineering is the property of Chinese Society of Agricultural Engineering and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Liquid Crystal & Displays is the property of Chinese Journal of Liquid Crystal & Displays and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

肺纤维化是一种慢性进行性的肺间质疾病,其特征是细胞外基质(主要是胶原纤维)在肺间质过度积聚。基质金属蛋白酶(MMPs)和其组织抑制因子(TIMPs)在肺发育、肺损伤和肺纤维化等病理生理过程中发挥重要作用,两者比例失衡是肺纤维化的发病机制之一。 [ABSTRACT FROM AUTHOR]

This experiment for determination of caffeine content was designed in the paper. Firstly, using solvent extract method, caffeine crystal was extracted from tea by ethanol as a solvent. Then the effect of mobile phase in sample separation has been investigated by HPLC. As increasing the concentration of methanol, the retention time of caffeine decreased accordingly. Next, the external standard method was established to detect the caffeine concentrations in high-performance liquid chromatography. The linear equation A = 2.38 C + 33.4 held a good linear fitting in the range of 20-100 μg / mL. and the square of the correlation coefficient was 0.991. Finally, caffeine concentrations in several beverages such as green tea, coke and energy drinks bought from supermarket were detected by HPLC, No interference peaks were observed in the chromatograms. Caffeine was found in all of these beverages, so the public should reduce intake of caffeine containing drinks. [ABSTRACT FROM AUTHOR]