447 results on '"Guo, G.Y."'
Search Results
152. Core level shifts and density of states at the (100) surface of Cu 3Au
- Author
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Jordan, R.G. and Guo, G.Y.
- Published
- 1998
- Full Text
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153. Relativistic effects on the structural and magnetic properties of iron
- Author
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Guo, G.Y., Ebert, H., Temmerman, W.M., Schwarz, K., and Blaha, P.
- Published
- 1991
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154. Source Analysis and Contamination Assessment of Potentially Toxic Element in Soil of Small Watershed in Mountainous Area of Southern Henan, China.
- Author
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Chen, Hang, Wu, Wei, Cao, Li, Zhou, Xiaode, Guo, Rentai, Nie, Liwei, and Shang, Wenxing
- Published
- 2022
- Full Text
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155. Effect of Mo and Cr on S-Induced Intergranular Fracture in γ-Fe.
- Author
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Liu, Si, Zhang, Yi, Ren, Junyu, Dong, Nan, Zhang, Caili, Ma, Jinyao, Jiang, Zhouhua, Li, Huabing, and Han, Peide
- Subjects
AUSTENITIC stainless steel ,CRYSTAL grain boundaries ,METALLIC bonds ,CORROSION resistance - Abstract
S is a common corrosion medium for austenitic stainless steels. The severe intergranular fracture of austenitic stainless steels occurs in sulfur environments. In this paper, the permeation of S at different atomic positions for three symmetric tilt grain boundary types, i.e., Σ5(210), Σ5(310), and Σ9(114) have been computed using first-principles calculations. S has the strongest segregation tendency in the Σ5(210) grain boundary. A high content of S at the grain boundary indicates harm to the grain boundary. Sulfur segregation in the grain boundaries can weaken the strength of the metallic bond. When Mo and Cr are present at the Σ5(210) grain boundary, the sulfur-induced embrittlement is inhibited. With increased S concentration at the grain boundary, the coexistence of Mo and Cr can suppress the intergranular fracture of S on the grain boundary. The reason why high-Mo stainless steel has excellent sulfur-induced intergranular corrosion resistance is explained at the atomic level. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
156. An Improved Kinect Recognition Method for Identifying Unsafe Behaviors of Metro Passengers.
- Author
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Lu, Ying, Yu, Yifan, Lv, Xifan, and Tao, Tingting
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KINECT (Motion sensor) ,FEATURE selection ,JOINTS (Anatomy) ,PASSENGERS - Abstract
In order to solve the problem of the low action recognition accuracy of passengers' unsafe behaviors caused by redundant joints, this study proposes an efficient recognition method based on a Kinect sensor. The method uses the pelvis as the starting point of the vector and high-frequency bone joints as the end point to construct the recognition feature vector. The joint angle difference between actions is obtained by using the cosine law, and the initial test result is converted into action similarity combined with the DTW similarity algorithm. Considering the combination of 3 angle features and 4 joint feature selection methods, 12 combined recognition models are formed. A comparative experiment was carried out to identify five types of unsafe behaviors of metro passengers—punch, one-armed call for help, arms for help, trip forward and trip backwards. The results show that the overall selection of joints has a poor similarity effect and cannot achieve the purpose of recognition. The overall recognition model effect of the local "pelvis divergence method" is higher than that of the local "adjacent joint method", and the local "pelvis divergence method" has the highest recognition result of the maximum angle difference model, and the recognition results of the five unsafe behaviors are 86.9%, 89.2%, 85.5%, 86.7%, and 88.3%, respectively, and the recognition accuracy of this method is 95.7%, indicating the feasibility of the model. The recognition results are more concentrated and more stable, which significantly improves the recognition rate of metro passengers' unsafe behavior. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
157. Compact 15 mJ Fiber–Solid Hybrid Hundred-Picosecond Laser Source for Laser Ablation on Copper.
- Author
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Wang, Tingting, Wang, Jing, Zhao, Meng, Peng, Hao, Zhou, Jianwei, Qu, Guannan, Tan, Yong, and Cai, Hongxing
- Subjects
LASER ablation ,SOLID-state lasers ,FIBER lasers ,FIBER Bragg gratings ,SINGLE-mode optical fibers ,LASERS - Abstract
We report on a millijoule-level fiber–solid hybrid hundred-picosecond laser system with a stable performance and compact structure. The laser system is based on a master oscillator power amplifier structure containing an all-fiber master oscillator, a quasi-continuous-wave side-pumped Nd:YAG regenerative amplifier, and a double-pass amplifier. By using the filtering effect of fiber Bragg grating and the dispersion characteristics of single-mode fiber stretcher, the spectrum broadening caused by self-phase modulation effect is effectively suppressed. Thus, the gain linewidth of the Yb-doped fiber seed source and Nd:YAG laser amplifiers is accurately matched. The reason for thermally induced depolarization in the solid-state laser amplifier is theoretically analyzed, and a more flexible depolarization compensation structure is adopted in amplifier experiment. Furthermore, the pulse energy of 14.58 mJ and pulse width of 228 ps is achieved at 500 Hz repetition rate. The central wavelength is 1064.1 nm with a 3 dB bandwidth of 0.47 nm. The beam quality factors in the horizontal and vertical directions are 1.49 and 1.51, respectively. This laser system has a simple and compact structure and has a power stability of 1.9%. The high pulse energy and beam quality of this hundred-picosecond laser are confirmed by latter theoretical simulation of copper laser ablation. It is a very practical laser system for material processing and laser-induced damage. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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158. Research on the Deformation and Failure Characteristics and Control Technology of Mining Area Rises under the Influence of Mining Stress.
- Author
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Jiang, Chongyang, Wang, Lianguo, Tang, Furong, Li, Zhaolin, Wang, Shuai, and Ren, Bo
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COAL mining ,DEFORMATIONS (Mechanics) ,ROCK deformation ,MINING engineering ,MATERIAL plasticity - Abstract
Affected by mining stress, roadways surrounding rock face problems such as serious deformation and failure and difficult support. In this study, with the II2 mining area rise in Taoyuan Coal Mine taken as the engineering background, the evolution laws of stress, deformation and plastic zone area of the mining area rises during the advance process of the working face were explored with the aid of FLAC
3D software. The results suggested that the stress, deformation and plastic zone area of the surrounding rock increase significantly when the distance between the working face and the track rise is less than 20 m. Based on this finding, it was further determined that the stopping line of the II82 22 working face should be at least 20 m away from the track rise. Furthermore, in accordance with the deformation and failure characteristics of surrounding rock under the influence of mining stress, this paper conducted a simulation on four support schemes of mining area rises, and quantitatively analyzed the mechanical response of a roadway surrounding rock under these support schemes. The simulation results revealed that the support scheme of "bolt-mesh-spray-cable + grouting bolt" can effectively deal with the influence of mining stress on the working face. Meanwhile, an engineering application was carried out. By monitoring the surface displacement of the surrounding rock, it was found that the deformation of the roadway surrounding rock was effectively controlled, and a remarkable support effect was achieved. In short, the proposed support scheme greatly improved the stability and safety of surrounding rock in the mining area rise under the influence of mining stress. [ABSTRACT FROM AUTHOR]- Published
- 2022
- Full Text
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159. Magneto-Optics Effects: New Trends and Future Prospects for Technological Developments.
- Author
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Rizal, Conrad, Shimizu, Hiromasa, and Mejía-Salazar, Jorge Ricardo
- Subjects
OPTICAL modulation ,INDUSTRIAL capacity ,INDUSTRIAL applications ,DRUGS - Abstract
Magneto-optics (MO) is an effervescent research field, with a wide range of potential industrial applications including sensing, theranostics, pharmaceutics, magnetometry, and spectroscopy, among others. This review discusses the historical development, from the discovery of MO effects up to the most recent application trends. In addition to the consolidated fields of magnetoplasmonic sensing and modulation of optical signals, we describe novel MO materials, phenomena, and applications. We also identified the emerging field of all-dielectric magnetophotonics, which hold promise to overcome dissipation from metallic inclusions in plasmonic nanostructures. Moreover, we identified some challenges, such as the need to merge magneto-chiroptical effects with microfluidics technology, for chiral sensing and enantioseparation of drugs in the pharmaceutical industry. Other potential industrial applications are discussed in light of recent research achievements in the available literature. [ABSTRACT FROM AUTHOR]
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- 2022
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160. Dynamic Changes of Volatile Compounds during the Xinyang Maojian Green Tea Manufacturing at an Industrial Scale.
- Author
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Yin, Peng, Wang, Jing-Jing, Kong, Ya-Shuai, Zhu, Yao, Zhang, Jun-Wei, Liu, Hao, Wang, Xiao, Guo, Gui-Yi, Wang, Guang-Ming, and Liu, Zhong-Hua
- Subjects
FOOD aroma ,GREEN tea ,EPIGALLOCATECHIN gallate ,GAS chromatography/Mass spectrometry (GC-MS) ,MANUFACTURING processes ,HIERARCHICAL clustering (Cluster analysis) - Abstract
Xinyang Maojian (XYMJ) is one of the premium green teas and originates from Xinyang, which is the northernmost green tea production area in China. The special geographic location, environmental conditions, and manufacturing process contribute to the unique flavor and rich nutrition of XYMJ green tea. Aroma is an important quality indicator in XYMJ green tea. In order to illustrate the aroma of XYMJ green tea, the key odorants in XYMJ green tea and their dynamic changes during the manufacturing processes were analyzed by headspace solid-phase microextraction (HS-SPME) combined with gas chromatography-mass spectrometry (GC-MS). A total of 73 volatile compounds of six different chemical classes were identified in the processed XYMJ green tea samples, and the manufacturing processes resulted in the losses of total volatile compounds. Among the identified volatile compounds, twenty-four aroma-active compounds, such as trans-nerolidol, geranylacetone, nonanal, (+)-δ-cadinene, linalool, (Z)-jasmone, cis-3-hexenyl butyrate, cis-3-hexenyl hexanoate, methyl jasmonate, and β-ocimene, were identified as the key odorants of XYMJ green tea based on odor activity value (OAV). The key odorants are mainly volatile terpenes (VTs) and fatty acid-derived volatiles (FADVs). Except for (+)-δ-cadinene, copaene, cis-β-farnesene, (Z,E)-α-farnesene and phytol acetate, the key odorants significantly decreased after fixing. The principal coordinate analysis (PCoA) and the hierarchical cluster analysis (HCA) analyses suggested that fixing was the most important manufacturing process for the aroma formation of XYMJ green tea. These findings of this study provide meaningful information for the manufacturing and quality control of XYMJ green tea. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
161. Nanotubes: Carbon-Based Fibers and Bacterial Nano-Conduits Both Arousing a Global Interest and Conflicting Opinions.
- Author
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Alfei, Silvana and Schito, Gian Carlo
- Subjects
CONFLICT of interests ,NANOTUBES ,CARBON nanotubes ,FIBERS ,BACTERIAL communities ,BACTERIAL cells - Abstract
Nanotubes (NTs) are mainly known as materials made from various substances, such as carbon, boron, or silicon, which share a nanosized tube-like structure. Among them, carbon-based NTs (CNTs) are the most researched group. CNTs, due to their nonpareil electrical, mechanical, and optical properties, can provide tremendous achievements in several fields of nanotechnology. Unfortunately, the high costs of production and the lack of unequivocally reliable toxicity data still prohibit their extensive application. In the last decade, a significant number of intriguing nanotubes-like structures were identified in bacteria (BNTs). The majority of experts define BNTs as membranous intercellular bridges that connect neighboring bacterial cell lying in proximity. Despite recent contrasting findings, most evidence suggested that bacteria exploit NTs to realize both antagonistic and cooperative intercellular exchanges of cytoplasmic molecules and nutrients. Among other consequences, it has been proposed that such molecular trade, including even plasmids, can facilitate the emergence of new non-heritable phenotypes and characteristics in multicellular bacterial communities, including resistance to antibiotics, with effects of paramount importance on global health. Here, we provide an enthralling comparison between CNTs, which are synthetically producible and ubiquitously exploitable for improving the quality of human life, and BNTs biosynthetically produced by prokaryotes, whose functions are not still fully clarified, but whose greater knowledge could be crucial to better understand the mechanisms of pathogenesis and combat the phenomenon of resistance. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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162. Double-Resolved Beam Steering by Metagrating-Based Tamm Plasmon Polariton.
- Author
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Bikbaev, Rashid G., Maksimov, Dmitrii N., Chen, Kuo-Ping, and Timofeev, Ivan V.
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POLARITONS ,BEAM steering ,REFRACTIVE index ,PLANE wavefronts - Abstract
We consider Tamm plasmon polariton in a subwavelength grating patterned on top of a Bragg reflector. We demonstrate dynamic control of the phase and amplitude of a plane wave reflected from such metagrating due to resonant coupling with the Tamm plasmon polariton. The tunability of the phase and amplitude of the reflected wave arises from modulation of the refractive index of a transparent conductive oxide layer by applying the bias voltage. The electrical switching of diffracted beams of the ±1st order is shown. The possibility of doubling the angular resolution of beam steering by using asymmetric reflected phase distribution with integer and half-integer periods of the metagrating is demonstrated. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
163. A Study on a Neural Network Risk Simulation Model Construction for Avian Influenza A (H7N9) Outbreaks in Humans in China during 2013–2017.
- Author
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Dong, Wen, Zhang, Peng, Xu, Quan-Li, Ren, Zhong-Da, and Wang, Jie
- Published
- 2022
- Full Text
- View/download PDF
164. Preparation and Application of Graphene and Derived Carbon Materials in Supercapacitors: A Review.
- Author
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Fang, Haiqiu, Yang, Dongfang, Su, Zizhen, Sun, Xinwei, Ren, Jiahui, Li, Liwei, and Wang, Kai
- Subjects
GRAPHENE ,SUPERCAPACITORS ,CAPACITORS ,SUPERCAPACITOR electrodes ,TRANSITION metal oxides ,METALLIC composites ,COMPOSITE materials - Abstract
Graphene has recently attracted a wide range of research interests due to its rigorous two-dimensional structure and extraordinary electrical, thermal and mechanical properties. As a conductive agent, an activated carbon supercapacitor can obtain better performance. This paper summarizes the latest research progress, mainly from two aspects: (1) the preparation of an activated carbon base for a supercapacitor based on waste sugar solution and the relationship between pore structure and activation parameters, and (2) the application of the two-dimensional materials graphene and its composite materials in electric double-layer capacitors, graphene–polymer composite tantalum capacitors, graphene–transition metal oxide composite tantalum capacitors, and asymmetric super capacitors. The studies found that graphene and its composite materials have obvious advantages in improving the cycle efficiency, conversion rate, and energy density of supercapacitors, the overall energy efficiency of mechanical systems, and the chemical properties of nanoelectronics. Therefore, it is urgent to summarize these works in order to promote the next development. Graphene is expected to be effectively and environmentally quantified in the near future, and its application in supercapacitors will be further expanded and matured. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
165. Transcriptomic and Metabolomic Analysis of the Effects of Exogenous Trehalose on Salt Tolerance in Watermelon (Citrullus lanatus).
- Author
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Yuan, Gaopeng, Sun, Dexi, An, Guolin, Li, Weihua, Si, Wenjing, Liu, Junpu, and Zhu, Yingchun
- Subjects
TREHALOSE ,WATERMELONS ,LIQUID chromatography-mass spectrometry ,METABOLOMICS ,TRANSCRIPTOMES ,SALT - Abstract
Trehalose can effectively protect the biomolecular structure, maintain the balance of cell metabolism, and improve the tolerance to various abiotic stresses in plants. However, the molecular mechanism underlying the improvement in salt tolerance by exogenous trehalose in watermelon (Citrullus lanatus) seedlings is still unclear. To understand these molecular mechanisms, in this study, watermelon seedlings under salt stress were treated with various concentrations of exogenous trehalose. An amount of 20 mM exogenous trehalose significantly improved the physiological status; increased the activities of enzymes such as POD, SOD, and CAT; and increased the K
+ /Na+ ratio in watermelon seedlings under salt stress. RNA-seq and metabolomic analysis were performed to identify the specifically expressed genes and metabolites after trehalose treatment. Watermelon seedlings were divided into salt stress (CK2), control (CK1) and trehalose treatment (T) groups as per the treatment. Overall, 421 shared differentially expressed genes (DEGs) were identified in the two comparison groups, namely CK2–CK1 and T–CK2. Functional annotation and enrichment analysis revealed that the DEGs were mainly involved in MAPK signaling pathway for plant hormone signal transduction and phenylpropanoid biosynthesis. Furthermore, 129 shared differential expressed metabolites (DEMs) were identified in the two comparison groups using liquid chromatography–mass spectrometry, which were mainly involved in the metabolic pathway and phenylpropanoid biosynthesis. The combined transcriptomic and metabolomic analyses revealed that genes involved in phenylpropanoid biosynthesis, plant hormone signal transduction, and carbohydrate biosynthesis pathways, especially bHLH family transcription factors, played an important role in improving salt tolerance of watermelon seedlings after exogenous trehalose treatment. [ABSTRACT FROM AUTHOR]- Published
- 2022
- Full Text
- View/download PDF
166. Comparative and Phylogenetic Analysis of Complete Chloroplast Genomes in Leymus (Triticodae, Poaceae).
- Author
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Wu, Zinian, Tian, Chunyu, Yang, Yanting, Li, Yuanheng, Liu, Qian, Li, Zhiyong, and Jin, Ke
- Subjects
CHLOROPLAST DNA ,BIOLOGICAL classification ,WHOLE genome sequencing ,POPULATION genetics ,GRASSES ,TANDEM repeats - Abstract
Leymus is a perennial genus that belongs to the tribe Triticeae (Poaceae) which has an adaptive capacity to ecological conditions and strong resistance to cold, drought, and salinity. Most Leymus species are fine herbs that can be used for agriculture, conservation, and landscaping. Due to confusion taxonomy within genera, the complete chloroplast (cp) genome of 13 Leymus species was sequenced, assembled, and compared with those of three other previously published Leymus species (Leymus condensatus, Leymus angustus, and Leymus mollis) to clarify the issue. Overall, the whole cp genome size ranged between 135,057 (L. condensatus) and 136,906 bp (Leymus coreanus) and showed a typical quadripartite structure. All studied species had 129 genes, including 83 protein-coding genes, 38 transfer RNAs, and 8 ribosomal RNAs. In total, 800 tandem repeats and 707 SSR loci were detected, most of which were distributed in the large single-copy region, followed by the inverted repeat (IR) and small single-copy regions. The sequence identity of all sequences was highly similar, especially concerning the protein-coding and IR regions; in particular, the protein-coding regions were significantly similar to those in the IR regions, regardless of small sequence differences in the whole cp genome. Moreover, the coding regions were more conserved than the non-coding regions. Comparisons of the IR boundaries showed that IR contraction and expansion events were reflected in different locations of rpl22, rps19, ndhH, and psbA genes. The close phylogenetic relationship of Leymus and Psathyrostachys indicated that Psathyrostachys possibly is the donor of the Ns genome sequence identified in Leymus. Altogether, the complete cp genome sequence of Leymus will lay a solid foundation for future population genetics and phylogeography studies, as well as for the analysis of the evolution of economically valuable plants. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
167. Ab Initio Phase Diagram of Chromium to 2.5 TPa.
- Author
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Baty, Samuel R., Burakovsky, Leonid, Luscher, Darby J., Sjue, Sky K., and Errandonea, Daniel
- Subjects
PHASE diagrams ,CHROMIUM isotopes ,EQUATIONS of state ,MELTING points ,EARTH'S core ,PHASE transitions ,CHROMIUM - Abstract
Chromium possesses remarkable physical properties such as hardness and corrosion resistance. Chromium is also a very important geophysical material as it is assumed that lighter Cr isotopes were dissolved in the Earth's molten core during the planet's formation, which makes Cr one of the main constituents of the Earth's core. Unfortunately, Cr has remained one of the least studied 3 d transition metals. In a very recent combined experimental and theoretical study (Anzellini et al., Scientific Reports, 2022), the equation of state and melting curve of chromium were studied to 150 GPa, and it was determined that the ambient body-centered cubic (bcc) phase of crystalline Cr remains stable in the whole pressure range considered. However, the importance of the knowledge of the physical properties of Cr, specifically its phase diagram, necessitates further study of Cr to higher pressure. In this work, using a suite of ab initio quantum molecular dynamics (QMD) simulations based on the Z methodology which combines both direct Z method for the simulation of melting curves and inverse Z method for the calculation of solid–solid phase transition boundaries, we obtain the theoretical phase diagram of Cr to 2.5 TPa. We calculate the melting curves of the two solid phases that are present on its phase diagram, namely, the lower-pressure bcc and the higher-pressure hexagonal close-packed (hcp) ones, and obtain the equation for the bcc-hcp solid–solid phase transition boundary. We also obtain the thermal equations of state of both bcc-Cr and hcp-Cr, which are in excellent agreement with both experimental data and QMD simulations. We argue that 2180 K as the value of the ambient melting point of Cr which is offered by several public web resources ("Wikipedia," "WebElements," "It's Elemental," etc.) is most likely incorrect and should be replaced with 2135 K, found in most experimental studies as well as in the present theoretical work. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
168. Responses of Tree Growth and Intrinsic Water Use Efficiency to Environmental Factors in Central and Northern China in the Context of Global Warming.
- Author
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Ren, Meng, Liu, Yu, Li, Qiang, Song, Huiming, Cai, Qiufang, and Sun, Changfeng
- Subjects
WATER efficiency ,TREE growth ,GLOBAL warming ,TREE-rings ,ECOLOGICAL zones ,CARBON isotopes ,STABLE isotopes - Abstract
The Loess Plateau is a fragile ecological zone that is sensitive to climate change. The response, adaptation, and feedback of tree growth in forest ecosystems to global warming and CO
2 enrichment are urgent scientific issues. Intrinsic water use efficiency (iWUE) is an important indicator for understanding forest ecosystem adaptability to climate change and CO2 enrichment. In this study, tree-ring width, tree-ring stable carbon isotope ratio (δ13 C), and iWUE of P. tabulaeformis Carr. were established. Climate response analysis showed that temperature was the main limiting factor affecting radial tree growth and that relative humidity significantly affected the stable carbon isotope fractionation of tree rings. During 1645–2011, the iWUE increased by 27.1%. The responses of iWUE to climate factors and atmospheric CO2 concentrations (Ca ) showed that the long-term variation in iWUE was affected by Ca , which could explain 69% of iWUE variation, and temperature was the main factor causing iWUE interannual variation. The ecosystem of P. tabulaeformis showed a positive response to rising Ca , as its carbon sequestration capacity increased. In response to global warming and CO2 enrichment, rising Ca promoted increases in iWUE but ultimately failed to offset the negative impact of warming on tree growth in the study area. [ABSTRACT FROM AUTHOR]- Published
- 2022
- Full Text
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169. Nanocrystalline (AlTiVCr)N Multi-Component Nitride Thin Films with Superior Mechanical Performance.
- Author
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Feng, Chuangshi, Feng, Xiaobin, Guan, Zhou, Song, Hongquan, Wang, Tianli, Liao, Weibing, Lu, Yang, and Zhang, Fuxiang
- Subjects
THIN films ,DC sputtering ,NITRIDES ,SILICON nitride films ,WEAR resistance ,COMPRESSIVE strength ,MECHANICAL alloying - Abstract
Multi-component nitride thin films usually show high hardness and good wear resistance due to the nanoscale structure and solid-solution strengthening effect. However, the state of N atoms in the thin film and its effects on the compressive strength is still unclear. In this work, (AlTiVCr)N multi-component nitride thin films with a face-centered cubic (FCC) structure prepared by the direct current magnetron sputtering method exhibit a superior strength of ~4.5 GPa and final fracture at a strain of ~5.0%. The excellent mechanical properties are attributed to the synergistic effects of the nanocrystalline structure, covalent bonding between N and metal atoms, and interstitial strengthening. Our results could provide an intensive understanding of the relationship between microstructure and mechanical performances for multi-component nitride thin films, which may promote their applications in micro- and nano-devices. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
170. Efficacy and Safety of Oral Green Tea Preparations in Skin Ailments: A Systematic Review of Clinical Studies.
- Author
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Di Sotto, Antonella, Gullì, Marco, Percaccio, Ester, Vitalone, Annabella, Mazzanti, Gabriela, and Di Giacomo, Silvia
- Abstract
Green-tea-based products and their polyphenols, especially epigallocatechin-3-gallate, have attracted great attention over the years as possible nutraceuticals, due to their promising bioactivities, especially antioxidant and anti-inflammatory, which could be exploited in several diseases, including skin ailments. In this context, the present study aimed at reviewing clinical evidence about the benefits of the oral administration of green tea preparations and its polyphenols to relieve skin disorders, to point out the current knowledge, and to suggest possible novel strategies to effectively exploit the properties of green tea, also managing safety risks. To this end, a systematic review of the existing literature was carried out, using the PRISMA method. Few studies, including five focused on UV-induced erythema and skin alterations, three on photoaging, two on antioxidant skin defenses, and one on acne and genodermatosis, were retrieved. Despite several benefits, clinical evidence only supports the use of oral green tea preparations to protect skin from damage induced by ultraviolet radiation; in other cases, conflicting results and methodological limits of clinical trials do not allow one to clarify their efficacy. Therefore, their application as adjuvant or alternative sunscreen-protective interventions could be encouraged, in compliance with the safety recommendations. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
171. Neutrophils and Neutrophil Extracellular Traps in Cardiovascular Disease: An Overview and Potential Therapeutic Approaches.
- Author
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Shirakawa, Kohsuke and Sano, Motoaki
- Subjects
THERAPEUTICS ,CARDIOVASCULAR diseases ,NEUTROPHILS ,VASCULAR endothelial cells ,VENOUS thrombosis ,ACUTE coronary syndrome - Abstract
Recent advances in pharmacotherapy have markedly improved the prognosis of cardiovascular disease (CVD) but have not completely conquered it. Therapies targeting the NOD-like receptor family pyrin domain containing 3 inflammasome and its downstream cytokines have proven effective in the secondary prevention of cardiovascular events, suggesting that inflammation is a target for treating residual risk in CVD. Neutrophil-induced inflammation has long been recognized as important in the pathogenesis of CVD. Circadian rhythm-related and disease-specific microenvironment changes give rise to neutrophil diversity. Neutrophils are primed by various stimuli, such as chemokines, cytokines, and damage-related molecular patterns, and the activated neutrophils contribute to the inflammatory response in CVD through degranulation, phagocytosis, reactive oxygen species generation, and the release of neutrophil extracellular traps (NETs). In particular, NETs promote immunothrombosis through the interaction with vascular endothelial cells and platelets and are implicated in the development of various types of CVD, such as acute coronary syndrome, deep vein thrombosis, and heart failure. NETs are promising candidates for anti-inflammatory therapy in CVD, and their efficacy has already been demonstrated in various animal models of the disease; however, they have yet to be clinically applied in humans. This narrative review discusses the diversity and complexity of neutrophils in the trajectory of CVD, the therapeutic potential of targeting NETs, and the related clinical issues. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
172. An R2R3-Type Transcription Factor OsMYBAS1 Regulates Seed Germination under Artificial Accelerated Aging in Transgenic Rice (Oryza sativa L.).
- Author
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Wu, Rong, Ding, Yunqian, Li, Chenyong, Wu, Bangkui, Huang, Zhongji, Li, Zhenan, Wang, Xiaomin, and Zhao, Guangwu
- Subjects
TRANSGENIC rice ,GERMINATION ,TRANSCRIPTION factors ,RICE ,RICE seeds ,SUPEROXIDE dismutase - Abstract
MYB-type transcription factors play an essential regulatory role in seed germination and the response to seedling establishment stress. This study isolated a rice R2R3-MYB transcription factor, OsMYBAS1, and functionally characterized its role in seed germination. There was no significant difference in the germination rate of each transgenic line in the standard germination test. However, compared to the germination rate of the wild type (WT) measured in the artificial accelerated aging test, the germination rates of the overexpression lines OE-OsMYBAS1-1 and OE-OsMYBAS1-2 were significantly increased by 25.0% and 21.7%, respectively. In contrast, the germination rates of the knockout mutants osmybas1-1 and osmybas1-2 were decreased by 21.7% and 33.3%, respectively. Additionally, the above data indicated that OsMYBAS1 possibly plays a positive role in rice seed germination. Moreover, the antioxidant enzyme activities of OsMYBAS1-overexpressing plants were enhanced by 38.5% to 151.0% while the superoxide dismutase (SOD) enzyme activity of osmybas1 mutants was decreased by 27.5%, and the malondialdehyde (MDA) content was increased by 24.7% on average. Interestingly, the expression of the antioxidation-related genes OsALDH3, OsAPX3, and OsCATC was enhanced in the OsMYBAS1 overexpression lines, which is consistent with the above results. Furthermore, transcriptome sequencing determined 284 differentially expressed genes (DEGs), which were mainly involved in the carbohydrate metabolic process, glycerolipid metabolism, and glycerophospholipid metabolism. Therefore, these findings provide valuable insight into the breeding of new rice varieties with high seed germination. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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- View/download PDF
173. Design of Multifunctional Tunable Metasurface Assisted by Elastic Substrate.
- Author
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Li, Jing, Fan, Hongjie, Ye, Han, Wu, Tiesheng, Sun, Yuhang, Wang, Xueyu, and Liu, Yumin
- Subjects
DIELECTRIC resonators ,OPTICAL devices ,RESONATORS ,POLYDIMETHYLSILOXANE ,BEAM splitters - Abstract
Metasurfaces with both multifunctionality and tunability hold great application potential in next-generation optical devices. In this paper, we propose a stretchable metasurface composed of arrays of identical dielectric rectangular resonators embedded in the polydimethylsiloxane (PDMS) substrate. It is shown that the metasurface possesses three functions at the operating wavelength of 532 nm. The switching of functions can be implemented by changing the period Px of the metasurface, induced by stretching the PDMS substrate along the x-direction. When the period Px is less than the operating wavelength of 532 nm, the behavior of metasurface can switch between transmissive window and reflective mirror. When the period Px of the metasurface varies from 532 nm to 700 nm, the metasurface act as a dynamic equal-power beam splitter with conversion efficiency higher than 90%, and the corresponding splitting angle can be adjusted from 90° to around 49.5°. Moreover, we achieve the switching of transmissive window/reflective mirror/split-ratio-variable splitter based on the metasurface consisting of arrays of identical L-shaped resonators embedded in the PDMS substrate. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
174. Parametric Quantile Regression Models for Fitting Double Bounded Response with Application to COVID-19 Mortality Rate Data.
- Author
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Gallardo, Diego I., Bourguignon, Marcelo, Gómez, Yolanda M., Caamaño-Carrillo, Christian, and Venegas, Osvaldo
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QUANTILE regression ,REGRESSION analysis ,DEATH rate ,COVID-19 ,RATE setting - Abstract
In this paper, we develop two fully parametric quantile regression models, based on the power Johnson S B distribution for modeling unit interval response in different quantiles. In particular, the conditional distribution is modeled by the power Johnson S B distribution. The maximum likelihood (ML) estimation method is employed to estimate the model parameters. Simulation studies are conducted to evaluate the performance of the ML estimators in finite samples. Furthermore, we discuss influence diagnostic tools and residuals. The effectiveness of our proposals is illustrated with a data set of the mortality rate of COVID-19 in different countries. The results of our models with this data set show the potential of using the new methodology. Thus, we conclude that the results are favorable to the use of proposed quantile regression models for fitting double bounded data. [ABSTRACT FROM AUTHOR]
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- 2022
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175. Booster Vaccination Decreases 28-Day All-Cause Mortality of the Elderly Hospitalized Due to SARS-CoV-2 Delta Variant.
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Müller, Veronika, Polivka, Lorinc, Valyi-Nagy, Istvan, Nagy, Alexandra, Szekanecz, Zoltan, Bogos, Krisztina, Vago, Hajnalka, Kamondi, Anita, Fekete, Ferenc, Szlavik, Janos, Elek, Jeno, Surján, György, Surján, Orsolya, Nagy, Péter, Schaff, Zsuzsa, Müller, Cecília, Kiss, Zoltan, and Kásler, Miklós
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SARS-CoV-2 Delta variant ,BOOSTER vaccines ,MORTALITY ,OLDER people ,HOSPITAL admission & discharge - Abstract
(1) Background: SARS-CoV-2 infections are associated with an increased risk of hospital admissions especially in the elderly (age ≥ 65 years) and people with multiple comorbid conditions. (2) Methods: We investigated the effect of additional booster vaccinations following the primary vaccination series of mRNA, inactivated whole virus, or vector vaccines on infections with the SARS-CoV-2 delta variant in the total Hungarian elderly population. The infection, hospital admission, and 28-day all-cause mortality of elderly population was assessed. (3) Results: A total of 1,984,176 people fulfilled the criteria of elderly including 299,216 unvaccinated individuals, while 1,037,069 had completed primary vaccination and 587,150 had obtained an additional booster. The primary vaccination series reduced the risk of infection by 48.88%, the risk of hospital admission by 71.55%, and mortality by 79.87%. The booster vaccination had an additional benefit, as the risk of infection, hospital admission, and all-cause mortality were even lower (82.95%; 92.71%; and 94.24%, respectively). Vaccinated patients needing hospitalization suffered significantly more comorbid conditions, indicating a more vulnerable population. (4) Conclusions: Our data confirmed that the primary vaccination series and especially the booster vaccination significantly reduced the risk of the SARS-CoV-2 delta-variant-associated hospital admission and 28-day all-cause mortality in the elderly despite significantly more severe comorbid conditions. [ABSTRACT FROM AUTHOR]
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- 2022
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176. Exogenous Proline Optimizes Osmotic Adjustment Substances and Active Oxygen Metabolism of Maize Embryo under Low-Temperature Stress and Metabolomic Analysis.
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Zuo, Shiyu, Zuo, Yuetao, Gu, Wanrong, Wei, Shi, and Li, Jing
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BETAINE ,STRAINS & stresses (Mechanics) ,PROLINE ,ORGANIC acids ,PENTOSE phosphate pathway ,CORN - Abstract
Maize (Zea mays L.) is more sensitive to low-temperature stress in the early growth period. The study was to explore the response mechanism of proline to low-temperature stress during maize seed germination. Maize varieties Xinxin 2 (low-temperature insensitive) and Damin 3307 (low-temperature sensitive) were chosen as the test materials, setting the normal temperature for germination (22 °C/10 °C, 9d), low-temperature germination (4 °C/4 °C, 5d) and normal temperature recovery (22 °C/10 °C, 4d), combined with proline (15 mmol·L
−1 ) soaking treatment, to study its effects on the osmotic regulation system and antioxidant protection system of maize embryos. Metabolomics analysis was carried out to initially reveal the basis of the metabolic regulation mechanism. The results showed that the activities of superoxide dismutase (SOD), peroxidase (POD), ascorbic acid peroxidase (APX) and glutathione reductase (GR) were induced to some extent under low-temperature stress. The activities of SOD, POD, APX and GR were further enhanced in the soaking seeds with proline. Proline treatment improved the activities of catalase (CAT), monodehydrated ascorbic acid reductase (MDHAR) and dehydroascorbic acid (DHAR), increased the contents of ascorbic acid (AsA) and glutathione (GSH) and decreased the contents of oxidized ascorbic acid (DHA) and reduced glutathione (GSSG) under low-temperature stress. The ratio of AsA/DHA and GSH/GSSG increased. The increase in antioxidant enzyme activity and the content of antioxidants can help to maintain the stability of the AsA-GSH cycle, and effectively reduce the production rate of superoxide anion (O2 • − ), hydrogen peroxide (H2 O2 ) and malondialdehyde (MDA). Based on the UPLC-MS/MS detection platform and self-built database, 589 metabolites were detected in each treated maize embryo; 262 differential metabolites were obtained, including 32 organic acids, 28 amino acids, 20 nucleotides and their derivatives, 26 sugars and alcohols, 46 lipids, 51 alkaloids, 44 phenols and 15 other metabolites. Sixty-eight metabolic pathways involving different metabolites were obtained by KEGG enrichment analysis. The results showed that proline increased the accumulation of sorbitol, planteose, erythritose 4-phosphate, arabinose and other saccharides and alcohols in response to low-temperature stress, increased the content of osmoregulation substances under low-temperature stress. Proline also restored the TCA cycle by increasing the content of α-ketoglutarate and fumaric acid. Proline increased the contents of some amino acids (ornithine, proline, glycine, etc.), alkaloids (cocamidopropyl betaine, vanillylamine, 6-hydroxynicotinic acid, etc.), phenols (phenolic ayapin, chlorogenic acid, etc.) and vitamins (ascorbic acid, etc.) in the embryo under low-temperature stress. Combined with pathway enrichment analysis, proline could enhance the low-temperature stress resistance of germinated maize embryos by enhancing starch and sucrose metabolism, arginine and proline metabolism, biosynthesis of secondary metabolites, flavonoid biosynthesis and pentose phosphate pathway. [ABSTRACT FROM AUTHOR]- Published
- 2022
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177. Clinical Phenotypes and Mortality Biomarkers: A Study Focused on COVID-19 Patients with Neurological Diseases in Intensive Care Units.
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Morales Chacón, Lilia María, Galán García, Lídice, Cruz Hernández, Tania Margarita, Pavón Fuentes, Nancy, Maragoto Rizo, Carlos, Morales Suarez, Ileana, Morales Chacón, Odalys, Abad Molina, Elianne, and Rocha Arrieta, Luisa
- Subjects
COUGH ,NEUROLOGICAL intensive care ,INTENSIVE care units ,COVID-19 ,NEUROLOGICAL disorders ,PARKINSON'S disease - Abstract
Purpose: To identify clinical phenotypes and biomarkers for best mortality prediction considering age, symptoms and comorbidities in COVID-19 patients with chronic neurological diseases in intensive care units (ICUs). Subjects and Methods: Data included 1252 COVID-19 patients admitted to ICUs in Cuba between January and August 2021. A k-means algorithm based on unsupervised learning was used to identify clinical patterns related to symptoms, comorbidities and age. The Stable Sparse Classifiers procedure (SSC) was employed for predicting mortality. The classification performance was assessed using the area under the receiver operating curve (AUC). Results: Six phenotypes using a modified v-fold cross validation for the k-means algorithm were identified: phenotype class 1, mean age 72.3 years (ys)—hypertension and coronary artery disease, alongside typical COVID-19 symptoms; class 2, mean age 63 ys—asthma, cough and fever; class 3, mean age 74.5 ys—hypertension, diabetes and cough; class 4, mean age 67.8 ys—hypertension and no symptoms; class 5, mean age 53 ys—cough and no comorbidities; class 6, mean age 60 ys—without symptoms or comorbidities. The chronic neurological disease (CND) percentage was distributed in the six phenotypes, predominantly in phenotypes of classes 3 (24.72%) and 4 (35,39%); χ² (5) 11.0129 p = 0.051134. The cerebrovascular disease was concentrated in classes 3 and 4; χ² (5) = 36.63, p = 0.000001. The mortality rate totaled 325 (25.79%), of which 56 (17.23%) had chronic neurological diseases. The highest in-hospital mortality rates were found in phenotypes 1 (37.22%) and 3 (33.98%). The SSC revealed that a neurological symptom (ageusia), together with two neurological diseases (cerebrovascular disease and Parkinson's disease), and in addition to ICU days, age and specific symptoms (fever, cough, dyspnea and chilliness) as well as particular comorbidities (hypertension, diabetes and asthma) indicated the best prediction performance (AUC = 0.67). Conclusions: The identification of clinical phenotypes and mortality biomarkers using practical variables and robust statistical methodologies make several noteworthy contributions to basic and experimental investigations for distinguishing the COVID-19 clinical spectrum and predicting mortality. [ABSTRACT FROM AUTHOR]
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- 2022
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178. The Evaluation of the Biological Effects of Melanin by Using Silkworm as a Model Animal.
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Andoh, Vivian, Chen, Liang, Zhu, Feifei, Ge, Qi, Ma, Lin, Wang, Qiang, and Chen, Keping
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MELANINS ,SILKWORMS ,TEXTILE chemicals ,ANIMAL models in research ,TENSILE tests ,CRYSTAL structure ,COCOONS - Abstract
Melanin has been reported to have potential applications in industries such as cosmetics and food due to its anti-UV and antioxidative qualities. However, the corresponding data on its safety evaluation or biological consequences are fairly limited; such data are critical given its widespread use. The effect of different concentrations (1, 2, 3, and 4%) of melanin on growth status (larvae length and weight, cocoon weight, and morphology), the microstructure of the various tissues (fat body, silk gland, and midgut), and silk properties was studied by using the silkworm (bombyx mori) as the model organism. The weight and length of silkworm larvae fed with melanin were lower than the control, indicating that melanin appears to have a negative effect on the growth status of silkworms; however, the histophysiology analysis indicates that the cell morphologies are not changed, the XRD and FTIR spectra indicate that the secondary and crystalline structures of silks are also well preserved, and the thermogravimetric analysis and tensile test indicate that the thermal stability and mechanical properties are well maintained and even improved to some extent. Generally, it indicates that melanin has a certain inhibitory effect on the growth of silkworm larva but causes no harm to the cell microstructures or silk properties; this demonstrates that the safety of melanin as a food addictive should be considered seriously. The increase of thermal stability and mechanical properties shows that melanin may be a good chemical modifier in textile industries. [ABSTRACT FROM AUTHOR]
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- 2022
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179. UBA domain protein SUF1 interacts with NatA‐complex subunit NAA15 to regulate thermotolerance in Arabidopsis.
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Song, Ze‐Ting, Chen, Xiao‐Jie, Luo, Ling, Yu, Feifei, Liu, Jian‐Xiang, and Han, Jia‐Jia
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PROTEIN domains ,ARABIDOPSIS ,HEAT recovery ,HEAT shock proteins ,ACETYLTRANSFERASES - Abstract
Summary: During recovery from heat stress, plants clear away the heat‐stress‐induced misfolded proteins through the ubiquitin‐proteasome system (UPS). In the UPS, the recognition of substrate proteins by E3 ligase can be regulated by the N‐terminal acetyltransferase A (NatA) complex. Here, we determined that Arabidopsis STRESS‐RELATED UBIQUITIN‐ASSOCIATED‐DOMAIN PROTEIN FACTOR 1 (SUF1) interacts with the NatA complex core subunit NAA15 and positively regulates NAA15. The suf1 and naa15 mutants are sensitive to heat stress; the NatA substrate NSNC1 is stabilized in suf1 mutant plants during heat stress recovery. Therefore, SUF1 and its interactor NAA15 play important roles in basal thermotolerance in Arabidopsis. [ABSTRACT FROM AUTHOR]
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- 2022
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180. Importance of Tyrosine Phosphorylation in Hormone-Regulated Plant Growth and Development.
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Song, Weimeng, Hu, Li, Ma, Zhihui, Yang, Lei, and Li, Jianming
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PLANT growth ,PLANT development ,PHOSPHOPROTEIN phosphatases ,TYROSINE ,PROTEIN kinases - Abstract
Protein phosphorylation is the most frequent post-translational modification (PTM) that plays important regulatory roles in a wide range of biological processes. Phosphorylation mainly occurs on serine (Ser), threonine (Thr), and tyrosine (Tyr) residues, with the phosphorylated Tyr sites accounting for ~1–2% of all phosphorylated residues. Tyr phosphorylation was initially believed to be less common in plants compared to animals; however, recent investigation indicates otherwise. Although they lack typical protein Tyr kinases, plants possess many dual-specificity protein kinases that were implicated in diverse cellular processes by phosphorylating Ser, Thr, and Tyr residues. Analyses of sequenced plant genomes also identified protein Tyr phosphatases and dual-specificity protein phosphatases. Recent studies have revealed important regulatory roles of Tyr phosphorylation in many different aspects of plant growth and development and plant interactions with the environment. This short review summarizes studies that implicated the Tyr phosphorylation in biosynthesis and signaling of plant hormones. [ABSTRACT FROM AUTHOR]
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- 2022
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181. Experimental Study of the Plastic Zone and Stress Asymmetric Distribution in Roadway Layered Surrounding Rocks.
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Chen, Jiaren, Wu, Hai, Zhang, Xuan, Gao, Xu, Ling, Tao, and Zhang, Zizheng
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DISTRIBUTION (Probability theory) ,STRESS concentration ,PLASTICS ,ROCK deformation ,ROCK concerts - Abstract
Featured Application: The research in this paper is of great significance for grasping the development pattern of the plastic zone and the stress distribution of the roadway (tunnel) layered surrounding rock. It has an important reference value for the support problem of a roadway (tunnel) and the design of the surrounding rock support scheme. A three-axis experimental simulation model was established for a roadway with layered surrounding rock by a 20 MPa true triaxial analog simulation equipment, and the corresponding layered surrounding rock numerical simulation model was established by discrete element software. The simulation results showed that the deformation of the roadway layered surrounding rock showed asynchronous deformation with time and asymmetric deformation in space. The measured results of the multipoint displacement meter inside the surrounding rock showed that the order of displacement of surrounding rock from the four corners of the roadway to the center of the roadway were upper right, lower left, upper left, and lower right. Under the influence of the surrounding rock bedding, the shape of the plastic zone of the roadway surrounding rock was irregular. In the area where the rock layer and the surface of the roadway were tangent and in the vertical area between the rock layer and the surface of the roadway, the plastic zone had a large development depth. In other regions, the development depth of the plastic zone was smaller. As a result, the stress values obtained at the monitoring points in the surrounding rock at the same distance from the roadway surface were different, and the stress increase value of the monitoring points in the plastic zone was not large (No. 929). With the expansion of the plastic zone, the monitoring point change from outside the plastic zone to inside the plastic zone, its stress first increased and then decreased (No. 2 and No. 872). The experimental results are of great significance for understanding and controlling the development law of the plastic zone of a layered inclined rock roadway and the deformation control of the roadway layered surrounding rock. [ABSTRACT FROM AUTHOR]
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- 2022
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182. Study on the Dip Angle Effect of Asymmetric Deformation and Failure of the Gob-Side Coal–Rock Roadway in Gently Inclined Coal Seam.
- Author
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Gao, Lin, Zhan, Xinyu, Zhang, Pandong, Wen, Zhijie, Ma, Zhenqian, Kong, Dezhong, Kang, Xiangtao, and Han, Sen
- Abstract
In order to reveal the influence law of coal seam dip angle on the stability of the surrounding rock of the gob-side coal–rock roadway in a gently inclined coal seam (GCRGICS), the deformation characteristics of the surrounding rock under four different coal seam dip angles of this kind of roadway were studied by field investigation, theoretical analysis and numerical simulation. The results showed that, with the increase of the coal seam dip angle, the amount of the roadway roof subsidence and the deformation of the upper and lower side arc triangle coal along the coal–rock interface increased, and the maximum deformation was 479 and 950 mm, respectively, and the maximum slip deformation area gradually shifted from the upper side arc triangle coal to the lower side arc triangle coal. The asymmetric deformation characteristics of the surrounding rock became more and more obvious. The asymmetric deformation rate of the GCRGICS showed a V-shaped variation relationship with the coal seam dip angle, when the coal seam dip angle was 10°, the asymmetric deformation rate was the minimum, only 1.1%. The plastic zone of the surrounding rock expanded with the increase of the coal seam dip angle, and the new extension range was mainly located in the roof area of the roadway. [ABSTRACT FROM AUTHOR]
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- 2022
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183. Acute Coronary Syndrome in the COVID-19 Era—Differences and Dilemmas Compared to the Pre-COVID-19 Era.
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Lasica, Ratko, Djukanovic, Lazar, Mrdovic, Igor, Savic, Lidija, Ristic, Arsen, Zdravkovic, Marija, Simic, Dragan, Krljanac, Gordana, Popovic, Dejana, Simeunovic, Dejan, Rajic, Dubravka, and Asanin, Milika
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ACUTE coronary syndrome ,COVID-19 ,COVID-19 pandemic ,MYOCARDIAL injury ,CORONARY thrombosis ,MYOCARDIAL infarction - Abstract
The COVID-19 pandemic has led to numerous negative implications for all aspects of society. Although COVID-19 is a predominant lung disease, in 10–30% of cases, it is associated with cardiovascular disease (CVD). The presence of myocardial injury in COVID-19 patients occurs with a frequency between 7–36%. There is growing evidence of the incidence of acute coronary syndrome (ACS) in COVID-19, both due to coronary artery thrombosis and insufficient oxygen supply to the myocardium in conditions of an increased need. The diagnosis and treatment of patients with COVID-19 and acute myocardial infarction (AMI) is a major challenge for physicians. Often the presence of mixed symptoms, due to the combined presence of COVID-19 and ACS, as well as possible other diseases, nonspecific changes in the electrocardiogram (ECG), and often elevated serum troponin (cTn), create dilemmas in diagnosing ACS in COVID-19. Given the often-high ischemic risk, as well as the risk of bleeding, in these patients and analyzing the benefit/risk ratio, the treatment of patients with AMI and COVID-19 is often associated with dilemmas and difficult decisions. Due to delays in the application of the therapeutic regimen, complications of AMI are more common, and the mortality rate is higher. [ABSTRACT FROM AUTHOR]
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- 2022
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184. Structures, Electronic Properties, and Gas Permeability of 3D Pillared Silicon Carbide Nanostructures.
- Author
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Arayawut, Onsuda, Kerdcharoen, Teerakiat, and Wongchoosuk, Chatchawal
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SILICON carbide ,PERMEABILITY ,SEPARATION of gases ,SMALL molecules ,CHEMICAL properties - Abstract
Silicon carbide (SiC) is recognized as excellent material for high power/temperature applications with a wide-band gap semiconductor. With different structures at the nanosize scale, SiC nanomaterials offer outstanding mechanical, physical, and chemical properties leading to a variety of applications. In this work, new 3D pillared SiC nanostructures have been designed and investigated based on self-consistent charge density functional tight-binding (SCC-DFTB) including Van der Waals dispersion corrections. The structural and electronic properties of 3D pillared SiC nanostructures with effects of diameters and pillar lengths have been studied and compared with 3D pillared graphene nanostructures. The permeability of small gas molecules including H
2 O, CO2 , N2 , NO, O2 , and NO2 have been demonstrated with different orientations into the 3D pillared SiC nanostructures. The promising candidate of 3D pillared SiC nanostructures for gas molecule separation application at room temperature is highlighted. [ABSTRACT FROM AUTHOR]- Published
- 2022
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185. Plasma Levels and Renal Handling of Amino Acids Contribute to Determination of Risk of Mortality or Feed of Ventilation in Patients with COVID-19.
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Bánfai, Gábor, Kanizsai, Péter, Csontos, Csaba, Kun, Szilárd, Lakatos, Ágnes, Lajtai, Anikó, Lelovics, Vanessza, Szukits, Sándor, Bogner, Péter, Miseta, Attila, Wittmann, István, and Molnár, Gergő A.
- Subjects
AMINO acids ,AMINO acid analysis ,COVID-19 ,COVID-19 pandemic ,CALCITONIN ,HOSPITAL mortality ,VENTILATION ,TRYPTOPHAN - Abstract
COVID-19 infection may lead to serious complications, e.g., need for mechanical ventilation or death in some cases. A retrospective analysis of patients referred to our COVID Emergency Department, indiscriminately, was performed. A routine lab analysis measured amino acids in plasma and urine of patients. Data of surviving and deceased patients and those requiring or not requiring mechanical ventilation were compared, and logistic regression analyses have been performed. Deceased patients were older, had higher blood glucose, potassium, AST, LDH, troponin, d-dimer, hsCRP, procalcitonin, interleukin-6 levels (p < 0.05 for all). They had lower plasma serine, glycine, threonine, tryptophan levels (p < 0.01), higher tyrosine and phenylalanine levels (p < 0.05), and higher fractional excretion of arginine, methionine, and proline (p < 0.05) than survivors. In a regression model, age, severity score of COVID-pneumonia, plasma levels of threonine and phenylalanine were predictors of in-hospital mortality. There was a difference in ventilated vs. non-ventilated patients in CT-scores, glucose, and renal function (p < 0.001). Using logistic regression, CT-score, troponin, plasma level, and fractional excretion of glycine were predictors of ventilation. Plasma levels and renal excretion of certain amino acids are associated with the outcome of COVID-19 infection beside other parameters such as the CT-score or age. [ABSTRACT FROM AUTHOR]
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- 2022
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186. Active Meta-Device for Dual-Transmission Windows with Tunable Angular Dispersion Characteristics.
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Li, Chenchen, Bai, Hui, Yan, Mingbao, Wang, He, Li, Zhiqiang, Wang, Wenjie, Wang, Jiafu, and Qu, Shaobo
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VARACTORS ,DISPERSION (Chemistry) ,REDSHIFT ,PLASMONICS - Abstract
Tailoring electromagnetic properties by meta-devices has aroused great interest with respect to manipulating light. However, the uncertainty of angular dispersion introduced by the incident waves prevents their further applications. Here, we propose a general paradigm for achieving dual-transmission windows while simultaneously eliminating the corresponding angular dispersions by a dynamic manner. The strategy of loading varactor diodes into a plasmonic meta-atom is used. In this way, the blue shifts of angular dispersion can be dynamically compensated by the red shifts introduced by the varactor diodes when driven by bias voltage. As a proof-of-principle, an active meta-atom with varactor diodes is presented. The varactor diodes embedded can independently regulate dual-transmission windows. The test results are consistent with the simulation ones. The presented meta-device is used for intelligent radome, angle-multiplexed communications, and incident-angle-insensitive equipment while providing tunable angular dispersion properties. [ABSTRACT FROM AUTHOR]
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- 2022
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187. Carbon Nanotori Reinforced Lubricants in Plastic Deformation Processes.
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Taha-Tijerina, Jose Jaime, Martínez, Juan Manuel, Euresti, Daniel, and Arquieta-Guillén, Patsy Yessenia
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MATERIAL plasticity ,METALLIC surfaces ,CARBON ,METALLIC composites - Abstract
This research presents the effects of carbon nanotori structures (CNst) dispersed as reinforcement for metal-working and metal-forming lubricants. Synthetic (SL) and deep drawing (DD) nanolubricants were prepared following a two-step method at 0.01 wt.%, 0.05 wt.%, and 0.10 wt.% filler fractions. Slight increases in viscosity (<6%) for nanolubricants were observed as filler fraction was increased through various measured temperatures. Tribological behavior of nanolubricants displayed superb improvements under antiwear and extreme pressure conditions. The load carrying capacity (p
oz ) increased by 16% and 22% at merely 0.01 wt.% CNst reinforcement and up to 73% and 107% at 0.10 wt.% filler fraction for SL and DD nanolubricants, respectively, compared to conventional materials. Additionally, at 0.10 wt.% wear scar evaluations showed a highest benefit of 16% and 24%, for SL and DD nanolubricants, respectively. This enhancement is attributed to diverse mechanisms such as rolling/sliding and load bearing effects, tribofilm formation, and CNst tribosintering behavior (at high pressures) onto metallic surfaces due to nanostructures size and morphology and their interlayer relationship among conventional lubricants. [ABSTRACT FROM AUTHOR]- Published
- 2022
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188. Effectiveness of Vitamin D Supplements among Patients Hospitalized for COVID-19: Results from a Monocentric Matched-Cohort Study.
- Author
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Fiore, Vito, De Vito, Andrea, Bagella, Paola, Princic, Elija, Mariani, Anna Antonella, Denti, Lucia, Fois, Alessandro Giuseppe, Madeddu, Giordano, Babudieri, Sergio, and Maida, Ivana
- Subjects
COVID-19 ,DIETARY supplements ,CHOLECALCIFEROL ,VITAMIN D ,NONINVASIVE ventilation ,CALCIUM supplements ,PROGNOSIS ,SURVIVAL rate - Abstract
Objectives: Our study aimed to evaluate the usefulness of Vitamin D3 (VitD3) among patients hospitalized for COVID-19. The primary endpoint was to evaluate the difference in survival rates between patients receiving and not VitD3. The secondary endpoints were to evaluate clinical outcomes, such as needing non-invasive ventilation (NIV), ICU transfer, and laboratory findings (inflammatory parameters). Methods: We conducted a retrospective, monocentric matched-cohort study, including patients attending our ward for COVID-19. Patients were divided into two groups depending on VitD3 administration (Group A) or not (Group B) among patients with low VitD levels (defined as blood levels < 30 ng/mL), which depended on physicians' judgment. Our internal protocol provides VitD3 100,000 UI/daily for two days. Findings: 58 patients were included in Group A, and 58 in Group B. Patients were matched for age, sex, comorbidities, COVID-19-related symptoms, PaO2/FiO2 ratio, blood exams, and medical treatments. Regarding the principal endpoint, there was a statistically significant difference between the two groups in survival rates [Group A vs. Group B = 3 vs. 11 (p = 0.042)]. When considering secondary endpoints, Group A patients were less likely to undergo NIV [Group A vs. Group B = 12 vs. 23 (p = 0.026)] and showed an improvement in almost all inflammatory parameters. Conclusions: The link between VitD3 deficiency and the clinical course of COVID-19 during hospitalization suggests that VitD3 level is a useful prognostic marker. Considering the safety of supplementation and the low cost, VitD3 replacement should be considered among SARS-CoV-2 infected patients needing hospitalization. [ABSTRACT FROM AUTHOR]
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- 2022
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189. Investigation of the Bearing Characteristics of Bolts on a Coal–Rock Combined Anchor Body under Different Pull-Out Rates.
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Zhang, Pandong, Gao, Lin, Zhan, Xinyu, Liu, Pengze, Kang, Xiangtao, Ma, Zhenqian, Wang, Yongyin, Liu, Ping, and Han, Sen
- Subjects
ROCK bolts ,DYNAMIC loads ,ANCHORS ,MECHANICAL failures ,DEBONDING ,COAL mining - Abstract
In order to reveal the influence of the pull-out rate on the load-bearing properties of the coal–rock combined anchor body, the mechanical properties and failure characteristics of a coal–rock combined anchor body under different pull-out rates (10, 20, 30, 40, 50 mm/min) were studied using the pull-out test and theoretical analysis. The results show that the bearing capacity of the bolt on the coal–rock combined anchor body improves under a dynamic load, but the load-bearing properties of the coal–rock combined anchor body are different from those of the full rock (coal) anchor body. With the increase in the pull-out rate, the maximum pull-out load of the bolt on the coal–rock combined anchor body increases first, then decreases, and finally tends to be stable. Under the condition of a low drawing rate, the bearing capacity of the coal–rock combined anchor system can be greatly improved, but when the pull-out rate exceeds 20 mm/min, the bearing capacity of the anchor system is reduced. The debonding process of the anchoring section of the coal–rock combined anchor body gradually expands from the beginning section of the anchor to the bottom of the borehole. The coal–rock combined anchor body undergoes time differential development of cracks, and the failure of the coal and rock mass occurs at different times. Its failure process can be divided into three stages: (1) the coal anchor and rock anchor act together; (2) the rock anchor acts alone; and (3) the coal anchor and rock anchor have residual action. [ABSTRACT FROM AUTHOR]
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- 2022
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190. Multi-Dimensional Evaluation Framework for the Sustainable Development of Forest Health Bases and Site Selection for Application in China.
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Fan, Chenjing, Zhou, Lingling, Gai, Zhenyu, Shen, Shiguang, Liu, Chu, and Li, Shiqi
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FOREST health ,SUSTAINABLE development ,FOREST management ,REGIONAL development ,SUSTAINABILITY ,MEDICAL tourism ,MULTIDIMENSIONAL databases - Abstract
In the context of global aging, people's awareness of health is deepening, and the rapid economic development has drawn widespread attention to the health tourism industry. As a way of experiencing health, forest health tourism is becoming increasingly favored, and the site selection and construction of forest health bases (FHBs) have also developed accordingly. To ensure sustainability in the process of the site selection and construction of FHBs, the suitability of regional development and the relative coordination of the market, environment, and resource levels should be considered. Although there have been numerous studies on sustainable forestry management, a comprehensive sustainability assessment framework based on development suitability and coordination in three dimensions is needed to guide the site selection and the construction of FHBs. The following tasks were carried out in this study: (1) based on market sustainability goals, environmental optimization goals, and ecological resource sustainability goals, a comprehensive sustainability evaluation framework for development suitability indicators and coordination indicators in three dimensions was established; (2) via the use of this framework, the construction potential of FHBs in 41,636 towns in China was evaluated; the evaluation results show that the towns in Anhui, Jiangxi, Guangdong, Guangxi, Fujian, Zhejiang, Hunan, Hubei, Guizhou, and other provinces of China generally have superior conditions for the development of FHBs; (3) a multi-dimensional comprehensive analysis of FHB site selection sustainability based on development suitability and coordination was carried out for four batches of approved pilots. The comprehensive analysis results demonstrate the worsening evaluation results of the four batches. The proposed framework can provide a reference for FHB development policies for countries worldwide. [ABSTRACT FROM AUTHOR]
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- 2022
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191. First-Principles Study on Possible Half-Metallic Ferrimagnetism in Double Perovskites Pb 2 XX′O 6 (X = Ti, Zr, Hf, V, Nb and Ta, X′ = Tc, Ru, Os and Rh).
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Chen, Bo-Yu, Lee, Po-Han, and Wang, Yin-Kuo
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PEROVSKITE ,PLATINUM group ,FERRIMAGNETISM ,STRUCTURAL optimization ,BAND gaps ,DENSITY of states - Abstract
Pb-based double perovskite compounds with chemical formula Phey have abundant physical properties in the spintronic field. Among all the features, the spin interaction of half-metallic (HM) is regarded as an important performance measure because of its high potential in spintronic devices. In this research study, we calculate density of state (DOS) to investigate possible half-metal candidates by executing structural optimization based on the method of generalized gradient approximation (GGA) and strong correlation effect (GGA + U). Furthermore, following the earlier methods by calculating and comparing energy difference of various compounds with the four initial magnetic states: ferromagnetic, ferrimagnetic, antiferromagnetic and nonmagnetic, we can determine which magnetic state is more stable. Results indicate that there are 13 possible ferrimagnetic HM candidates in these combinations, including Pb
2 NbTcO6 , Pb2 TaTcO6 , Pb2 TiRuO6 , Pb2 ZrRuO6 , Pb2 HfRuO6 , Pb2 VRuO6 , Pb2 NbRuO6 , Pb2 TadRuO6 , Pb2 ZrOsO6 , Pb2 HfOsO6 , Pb2 VOsO6 , Pb2 ZrRhO6 and Pb2 HfRhO6 under GGA and GGA + U schemes. The stability of analysis by analyzing the energy gap illustrates that all 13 possible candidates are half metals and ferrimagnetic states, so our studies could provide guidelines for scientists to fabricate new double perovskites in future. [ABSTRACT FROM AUTHOR]- Published
- 2022
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192. Evaluating the fermentation quality and bacterial community of high‐moisture whole‐plant quinoa silage ensiled with different additives.
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Fang, Di, Dong, Zhihao, Wang, Deling, Li, Bin, Shi, Pibiao, Yan, Jun, Zhuang, Dongying, Shao, Tao, Wang, Weiyi, and Gu, Minfeng
- Subjects
LACTIC acid fermentation ,BACTERIAL communities ,SILAGE ,FERMENTATION ,QUINOA ,SILAGE fermentation - Abstract
Aim: To explore the potential of whole‐plant quinoa (WPQ) as a high‐protein source for livestock feed, this study evaluated the effects of additives on the fermentation quality and bacterial community of high‐moisture WPQ silage. Methods and Results: High‐moisture WPQ was ensiled with one of the following additives: untreated control (C), fibrolytic enzyme (E), molasses (M), LAB inoculant (L), a combination of fibrolytic enzyme and LAB inoculant (EL) and a combination of molasses and LAB inoculant (ML). The fermentation quality and bacterial community after 60 days of ensiling were analysed. Naturally fermented WPQ exhibited acetic acid‐type fermentation dominated by enterobacteria, with low lactic acid content (37.0 g/kg DM), and high pH value (5.65), acetic acid (70.8 g/kg DM) and NH3‐N production (229 g/kg TN). Adding molasses alone or combined with LAB inoculant shifted the fermentation pattern towards increased intensity of lactic acid fermentation, lowering the pH value (<4.56), contents of acetic acid (<46.7 g/kg DM) and NH3‐N (<140 g/kg TN) and total abundance of enterobacteria (<16.0%), and increasing the lactic acid content (>60.5 g/kg DM), lactic/acetic acid ratio (>1.40) and the relative abundance of Lactobacillus (>83.0%). Conclusions: The results suggested that the lack of fermentable sugar could be the main factor of restricting extensive lactic acid fermentation in WPQ silage. Supplementing fermentable sugar or co‐ensiling with materials with high WSC content and low moisture content are expected to be beneficial strategies for producing high‐quality WPQ silage. Significance and Impact of Study: High biomass production and high protein content make WPQ to be an ideal forage source for livestock feed. Results of this study revealed the restricting factor for extensive lactic acid fermentation in WPQ silage, which could be helpful in producing high‐quality WPQ silage. [ABSTRACT FROM AUTHOR]
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- 2022
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193. Heterogeneity and Risk of Bias in Studies Examining Risk Factors for Severe Illness and Death in COVID-19: A Systematic Review and Meta-Analysis.
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Degarege, Abraham, Naveed, Zaeema, Kabayundo, Josiane, and Brett-Major, David
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HETEROGENEITY ,COVID-19 ,META-analysis ,PUBLICATION bias ,CINAHL database ,AGE factors in disease ,OLDER patients - Abstract
This systematic review and meta-analysis synthesized the evidence on the impacts of demographics and comorbidities on the clinical outcomes of COVID-19, as well as the sources of the heterogeneity and publication bias of the relevant studies. Two authors independently searched the literature from PubMed, Embase, Cochrane library, and CINAHL on 18 May 2021; removed duplicates; screened the titles, abstracts, and full texts by using criteria; and extracted data from the eligible articles. The variations among the studies were examined by using Cochrane, Q.; I
2 , and meta-regression. Out of 11,975 articles that were obtained from the databases and screened, 559 studies were abstracted, and then, where appropriate, were analyzed by meta-analysis (n = 542). COVID-19-related severe illness, admission to the ICU, and death were significantly correlated with comorbidities, male sex, and an age older than 60 or 65 years, although high heterogeneity was present in the pooled estimates. The study design, the study country, the sample size, and the year of publication contributed to this. There was publication bias among the studies that compared the odds of COVID-19-related deaths, severe illness, and admission to the ICU on the basis of the comorbidity status. While an older age and chronic diseases were shown to increase the risk of developing severe illness, admission to the ICU, and death among the COVID-19 patients in our analysis, a marked heterogeneity was present when linking the specific risks with the outcomes. [ABSTRACT FROM AUTHOR]- Published
- 2022
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194. Influence of Symmetry from Crystal Structure and Chemical Environments of Magnetic Ions on the Fully Compensated Ferrimagnetism of Full Heusler Cr 2 YZ and Mn 2 YZ Alloys.
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Wu, Zhigang, Zhang, Yajiu, Liu, Zhuhong, and Ma, Xingqiao
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HEUSLER alloys ,MAGNETIC ions ,CRYSTAL symmetry ,CHEMICAL structure ,FERRIMAGNETISM ,CRYSTAL structure - Abstract
Fully compensated ferrimagnets do not create any magnetic stray field and allow for a completely polarized current of charges. As a result, these alloys show promising prospects for applications as spintronic devices. In this paper, we investigated the phase stability, the site preference, the tetragonal distortion and the influence of symmetry from the crystal structure and chemical environments of magnetic ions on the magnetic properties of Cr
2 YZ and Mn2 YZ (Y = void, Ni, Cu, and Zn; Z = Ga, Ge, and As) full Heusler alloys by first-principles calculations. We found that the selected Cr2 -based alloys, except for Cr2 NiGa and Cr2 NiGe, prefer to crystallize in the centrosymmetric L21 -type structure, while the selected Mn2 -based alloys, except for Mn2 CuAs, Mn2 ZnGe and Mn2 ZnAs, tend to crystallize in the non-centrosymmetric XA-type structure. Due to the symmetry, the antiferromagnetism of the selected L21 -type alloys is very stable, and no spin-polarized density of states could be generated. In contrast, the magnetic moment of the selected XA-type alloys depends heavily on the number of valence electrons and tetragonal distortion, and spin-polarized density of states is generated. Therefore, the selected alloys with L21 -type structures and their tetragonal-distorted structure are potential candidates for conventional antiferromagnets, while those with XA-type structure and their tetragonal-distorted structure are promising candidates for (fully) compensated ferrimagnets. [ABSTRACT FROM AUTHOR]- Published
- 2022
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195. Structural Stability and Electronic Properties of Boron Phosphide Nanotubes: A Density Functional Theory Perspective.
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García-Toral, Dolores, Mendoza-Báez, Raúl, Chigo-Anota, Ernesto, Flores-Riveros, Antonio, Vázquez-Báez, Víctor M., Cocoletzi, Gregorio Hernández, and Rivas-Silva, Juan Francisco
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DENSITY functional theory ,STRUCTURAL stability ,PHASE transitions ,NANOTUBES ,BAND gaps - Abstract
Based on the Density Functional Theory (DFT) calculations, we analyze the structural and electronic properties of boron phosphide nanotubes (BPNTs) as functions of chirality. The DFT calculations are performed using the M06-2X method in conjunction with the 6-31G(d) divided valence basis set. All nanostructures, (n,0) BPNT (n = 5–8, 10, 12, 14) and (n,n) BPNT (n = 3–11), were optimized minimizing the total energy, assuming a non-magnetic nature and a total charge neutrality. Results show that the BPNT diameter size increases linearly with the chiral index "n" for both chiralities. According to the global molecular descriptors, the (3,3) BPNT is the most stable structure provided that it shows the largest global hardness value. The low chirality (5,0) BPNT has a strong electrophilic character, and it is the most conductive system due to the small |HOMO-LUMO| energy gap. The chemical potential and electrophilicity index in the zigzag-type BPNTs show remarkable chirality-dependent behavior. The increase in diameter/chirality causes a gradual decrease in the |HOMO-LUMO| energy gap for the zigzag BPNTs; however, in the armchair-type BPNTs, a phase transition is generated from a semiconductor to a conductor system. Therefore, the nanostructures investigated in this work may be suggested for both electrical and biophysical applications. [ABSTRACT FROM AUTHOR]
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- 2022
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196. A Review on the Development of XRD in Ferrite Nanoparticles.
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Jain, Richa
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BOND angles ,CRYSTAL lattices ,NANOPARTICLES ,CRYSTAL structure ,CHEMICAL bond lengths ,FERRITES - Abstract
In the present study, an overview of the aspects of X-ray diffraction (XRD) in ferrite has been explored. Ferrite nanoparticles have a wide range of applications in various fields. XRD data could be used to measure the phases, crystal structure, and related parameters of ferrites. It can also determine the effect of doping and substitution on the crystal structure of the ferrite and the strain on the crystal lattice due to these variations. Cation distribution, bond length, interionic distances, bond angles, and hopping length can be calculated using XRD for the fruitful discussion of various properties of ferrite. From this study, it can be revealed that XRD is the ideal technique to elucidate not only the crystal structure but also the magnetic, electrical, optical, elastic behavior which could be explained by analyzing the XRD data systematically. [ABSTRACT FROM AUTHOR]
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- 2022
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197. Frequency Down-Conversion of Optical Pulse to the Far Infrared and THz Frequency Ranges Due to the Cascading Process in a Medium with a Quadratic Nonlinear Response.
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Trofimov, Vyacheslav A., Kharitonov, Dmitry M., Fedotov, Mikhail V., and Yang, Yongqiang
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SUBMILLIMETER waves ,FEMTOSECOND pulses ,SYSTEM identification ,COMPUTER simulation ,RADIATION - Abstract
Difference-frequency generation is a well-known method of obtaining IR and THz radiation. It has many practical applications, such as sensing, optical metrology, diagnostics, detection and identification of substances, etc. One of the generation methods is based on the three-wave interaction in a medium with second-order nonlinear susceptibility. In this study, we investigated a special case of the frequency down-conversion into IR and THz ranges of the frequencies: the frequencies of interacting waves were multiple. We analyzed theoretically two cases of three-wave interactions: amplification of the infrared (or THz) radiation (incident weak intensity of a wave at this frequency) and a wave generation with the difference-frequency (incident zero-value intensity at this frequency). The amplification efficiency could achieve 75% and the maximal frequency conversion efficiency is about 25%. The computer simulation results made for the femtosecond pulse interaction in a crystal with the wavelength 4, 10, and 24 μm demonstrates applicability of such a scheme for the frequency down-conversion. This scheme of the THz radiation generation is a perspective tool for its application in the screening system for the detection and identification of substances. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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198. Widely Targeted Metabolomics Analysis Reveals the Differences of Nonvolatile Compounds in Oolong Tea in Different Production Areas.
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Wang, Zhihui, Gan, Shuang, Sun, Weijiang, and Chen, Zhidan
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TEA growing ,TEA ,METABOLOMICS ,FARM produce ,FLAVOR ,QUALITY control ,COMPLEX compounds - Abstract
The flavor differences in Oolong tea from different producing areas are caused by its complex differential compounds. In this study, representative samples of Oolong tea from four countries were collected, and their differential nonvolatile compounds were analyzed by a combination of widely targeted metabolomics, chemometrics, and quantitative taste evaluation. A total of 801 nonvolatile compounds were detected, which could be divided into 16 categories. We found that the difference in these compounds' content among Oolong teas from three producing areas in China was the largest. There were 370 differential compounds related to the producing areas of Oolong tea, which were mainly distributed in 67 Kyoto Encyclopedia of Genes and Genomes (KEGG) metabolic pathways. In total, 81 differential nonvolatile compounds made important contributions to the taste differences in Oolong tea from different producing areas, among which the number of flavonoids was the largest. Finally, the characteristic compounds of Oolong tea in six producing areas were screened. This study comprehensively identifies the nonvolatile compounds of Oolong tea in different producing areas for the first time, which provides a basis for the analysis of flavor characteristics, quality directional control, and the identification and protection of geographical landmark agricultural products of Oolong tea from different producing areas. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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199. Application of Stubble and Root Cutting in Artificial Cultivation of Non-Timber Forest Products (NTFPs): A Study Case of Aralia elata (Miq.) Seem.
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Zhang, Ting, Yu, Lizhong, Man, Yuan, Yan, Qiaoling, and Zhang, Jinxin
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NON-timber forest products ,PLANT size ,UNDERSTORY plants ,PLANT cuttings ,MEDICINAL plants ,GERMINATION ,ROOT growth - Abstract
The increased demand for non-timber forest products (NTFPs) has led to the over-exploitation and disordered utilization of wild NTFP resources. Thus, it is important to determine how to sustainably utilize and cultivate NTFPs. Stubble and root cutting are two important methods for artificial cultivation, but little is known about their effects on the artificial cultivation of NTFP species with strong sprouting ability. Aralia elata is an important understory economic plant with high medicinal and edible values, and its wild resources are decreasing rapidly due to increasing demand. Therefore, A. elata, with its strong sprouting ability, was taken as an example to explore the effects of stubble (plant size × stubble height) and root cutting (root-cutting distance × root-cutting ratio) on its growth and sprouting ability for three years. The results showed that both stubble and root-cutting treatments could effectively facilitate the root sprouting ability of A. elata. The short stubble height treatment (6–15 cm) was the optimum stubble method for large A. elata (the mean height and basal diameter of plants were 256.65 cm and 4 cm, respectively). For small A. elata (plant basal diameter ranged from 1.5 cm to 3.4 cm), the optimal root-cutting method was 100% root-cutting ratio at a root-cutting distance of 0.25 m. However, the effects of stubble and root cutting on the growth and sprouting ability of A. elata were time-dependent, and repetitive treatment might be applied at an interval of two years to maintain its continuous growth and sprouting. [ABSTRACT FROM AUTHOR]
- Published
- 2022
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200. Advances in Nanostructures for Antimicrobial Therapy.
- Author
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Jampilek, Josef and Kralova, Katarina
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PHOTOTHERMAL effect ,NANOSTRUCTURES ,METALLIC oxides ,ANTIMICROBIAL peptides ,ORGANIC conductors ,ANTIMICROBIAL polymers - Abstract
Microbial infections caused by a variety of drug-resistant microorganisms are more common, but there are fewer and fewer approved new antimicrobial chemotherapeutics for systemic administration capable of acting against these resistant infectious pathogens. Formulation innovations of existing drugs are gaining prominence, while the application of nanotechnologies is a useful alternative for improving/increasing the effect of existing antimicrobial drugs. Nanomaterials represent one of the possible strategies to address this unfortunate situation. This review aims to summarize the most current results of nanoformulations of antibiotics and antibacterial active nanomaterials. Nanoformulations of antimicrobial peptides, synergistic combinations of antimicrobial-active agents with nitric oxide donors or combinations of small organic molecules or polymers with metals, metal oxides or metalloids are discussed as well. The mechanisms of actions of selected nanoformulations, including systems with magnetic, photothermal or photodynamic effects, are briefly described. [ABSTRACT FROM AUTHOR]
- Published
- 2022
- Full Text
- View/download PDF
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