Search

The use of traditional and folklore systems of medicine has been an important part of healthcare worldwide, and polyherbal formulations, which are combinations of different herbs, are gaining recognition for their medicinal and therapeutic potential. These formulations can be optimized to have stronger therapeutic effects with lower toxicity. The aim of this study was to review research on the antimicrobial, anti-inflammatory, antioxidant and toxicological properties of polyherbal formulations around the world, with a view to promoting their use and identifying areas where further research is needed. The author analyzed 99 articles published between 2010 and 2022, using scientific search engines such as Elsevier, BioMed Central, ScienceDirect, PubMed, and Scopus, to assess the use of polyherbal formulations in different countries. This article enlists some commercial and non-commercial polyherbal formulations all around the world with India leading in the number of publications on polyherbal formulations, followed by Nigeria, and Pakistan. The various pharmacological studies conducted have shown that polyherbal medicines possess antimicrobial, anti-inflammatory, antioxidant and toxicological properties, hence, validating their traditional use. However, further clinical work is required to fully understand the therapeutic potential of polyherbal formulations. The growing interest in the therapeutic use of non-toxic conventional medicinal plants as low-cost alternatives for disease prevention and treatment has made natural products valuable tools for creating new lead compounds and scaffolds. Plants will continue to play a pivotal role in the discovery of drugs for human diseases, and the development of potent cures derived from plants would represent significant progress in the treatment of diseases. [ABSTRACT FROM AUTHOR]

Copyright of Jordan Journal of Pharmaceutical Sciences is the property of University of Jordan and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The enormous effects of food insecurity have worsened in Nigeria and are further heightened by internal conflicts combined with ongoing climate change impacts such as drought and floods. Moreover, food availability is affected by economic challenges especially a weakening of foreign exchange and fiscal revenues, which has reduced the rate of food importation and increased local prices. Furthermore, the geometric increase in population especially in the last five decades has placed enormous pressure on the limited food resources, making it more challenging for agricultural and food systems to sustainably meet local food needs. Put together, these indices are contributing significantly to undernourishment. The huge local legume resources if properly harnessed can contribute toward addressing food insecurity. However, most of the legumes are included in the United Nations' Food and Agriculture Organization list of underutilized crops. Also, there is an over-reliance on food high in calorie in Nigeria, which is discouraged by nutritionists worldwide. Plant-based protein from legumes is necessary for effective metabolism and human wellbeing. This work highlights the benefits of the sustainable utilization of neglected and underutilized legume resources in Nigeria. The work discusses potential solutions for food insecurity as well as avenues for improving human nutrition and wellbeing. [ABSTRACT FROM AUTHOR]